• Journal of Preventive Medicine and Public Health
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• 제50권2호
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• pp.127-132
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• 2017

Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A ${\beta}-hemolytic$ streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status. Methods: Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin. Results: The carriage of ${\beta}-hemolytic$ streptococci was detected in 18.1% of participants, with Streptococcus pyogenes in 18 participants followed by S. dysgalactiae ssp. equisimilis in 5. The highest proportion of GAS was found in 8 to 10-year-old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolide-resistant phenotypes (11.1%) were observed. Resistance to penicillin, cefotaxime, or chloramphenicol was not expressed in any streptococcal isolate. Conclusions: The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need for continuous surveillance of GAS and non-GAS carriage as well as of antimicrobial resistance in highly susceptible populations, such as school-aged rural children. An extended surveillance program including school-aged children from different cities should be considered to estimate the prevalence of GAS carriage in Argentina.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7929-7933
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• 2015

Background: The incidence of breast cancer in India is on the rise and is rapidly becoming the number one cancer in females, pushing the cervical cancer to the second position. Most of the predisposition to hereditary breast and ovarian cancer has been attributed to inherited defects in two tumor suppressor genes BRCA1 and BRCA2. Alterations in these genes have been reported in different populations, some of which are population-specific mutations showing founder effects. Two specific mutations in the BRCA1 (185delAG) and BRCA2 (6174delT) genes have been reported to be of high prevalence in different populations. The aim of this study was to estimate the carrier frequency of 185delAG and 6174delT mutations in eastern Indian breast cancer patients. Materials and Methods: We selected 231 histologically confirmed breast cancer patients from our tertiary cancer care center in eastern India. Family history was obtained by interview or a self-reported questionnaire. The presence of the mutation was investigated by allele specific duplex/multiplex-PCR on genomic DNA extracted from peripheral blood. Results: A total of 231 patients (age range: 26-77 years), 130 with a family history and 101 without were screened. The two founder mutations 185delAG in BRCA1 and 6174delT in BRCA2 were not found in any of the subjects. This was confirmed by molecular analysis. Conclusions: Our findings suggest that these BRCA mutations may not have a strong recurrent effect on breast cancer among the eastern Indian population. The contribution of these founder mutations to breast cancer incidence is probably low and could be limited to specific subgroups. This may be particularly useful in establishing further pre-screening strategies.

• Journal of Preventive Medicine and Public Health
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• 제33권1호
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• pp.31-35
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• 2000

Objectives : This study aimed to estimate the completeness of cancer registration with Capture-recapture method. Methods : The study was conducted in the population based cancer registry of Kwangju, Korea, for which there are three main sources of notification: reports by Korean Central Cancer Registry, reports by pathology data, and the others reports by radiology data, death certificates, etc. The defined cases in three sources were matched by 13 digits Resident Register Number. To derive an estimates, log-linear models were applicated. Results : Overall completeness was estimated to be around 93%. There was some variation with age(consistently high levels below age group 60-74 years, a minimum of 88.6% above 75 years). Among the most common cancer sites, estimates of completeness were highest for thyroid cancer(97.1%), while lower estimates of completeness were derived for stomach cancer(92.3%), liver cancer(92.6%). Conclusions : Careful application of Capture-recapture method may provide an alternative to traditional approaches for estimating the completeness of cancer registration in Kwangju city.

• 한국분무공학회지
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• 제23권2호
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• pp.81-89
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• 2018

The objective of this study is to estimate the level of exposure of traffic-related air pollutants (TRAPs) on the pedestrians in Seoul area. The road network's link-based pollutant emission was calculated by using a set of mobile source emission factor package and associated activity information. The population information, which is the number of pedestrian, was analyzed in conjunction with the link-based traffic emissions in order to quantify exposure level by selected 23 spots. We proposed the Exposure Intensity, which is defined by the amount of traffic emission and the population, to quantify the probability of exposure of pedestrian. Link-based traffic NOx and PM emissions vary by up to four times depending on the location of each spot. The Hot-spots is estimated to be around 1.8 times higher Exposure Intensity than the average of the 23 selected spots. The information of Exposure Intensity of each spot allows us to develop localized policies for air quality and health. Even in the same area, the Exposure Intensity over time also shows a large fluctuation, which gives suggestions for establishing site-specific counter-measures.

• 한국인구학
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• 제5권1호
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• pp.133-144
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• 1982

One of the primary objectives of Korean family planning program is to assist parents in having the number of children they want, both by providing fertility-en-hancing services to infecund and subfecund women and by providing fertility-limitation services to fecund women. As far as fertility-enhancing services to infecund and subfecund women is concerned, there has been little effort from the national family planning program, So far, there is no any basic data on infertility prevalence rate among the Korean women. Therefore, an attempt has been made to review data of 1976 and 1978 fertility and family planning surveys in order to estimate the level of infertility rate among the Korean women. In the 1978 survey 3. 7 percent of the current married women responded that they were physically infertile while in the 1976 survey physically infer-tile women was calculated as 3 percent of the total ever married women which is similar level of 1978 data of 3.7 percent. Mean age at first marriage of Korean women is 23 and most of the women are married in the high fecund age. Only 0.3 percent of the respondents married age 30. in addition, the rate of women with no children among the ever married women whose married duration is more than 5 year is very low;2. 5 percent among 5-9 years, 1. 4 percent among 10- 14 years; 1.8 precent among 15-19 years; 1.0 percent among 20-24 years; and 0. 7 percent among 25 or more years of marriage duration. If we consider those data shown above, it is manifest that infertility rate of Korean women is less than 5 percent level which is much lower than the 10 percent level of infertility rate in the United States of America. However, this kind of estimation is still not able to show definite data on fertility rate. Therefore, a nationwide planned survey should be carried out as early as possible to figure out the real situation of infertility rate in Korea.

• 한국작물학회지
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• 제45권5호
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• pp.347-351
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• 2000

Rye has been a major winter forage crop in Korea. Varietal improvement of rye has been practiced either by hybrid or population breeding systems. Hybrid breeding offers important advantages over population breeding since it is normally a cross-pollinated crop. The hybrid breeding in rye has been possible since cytoplasmically inherited forms of male sterility (CMS) and corresponding nuclear restorer genes were found. The objectives of this research were to develop the maintainer and restorer lines of Korean inbred lines and to estimate the effect of 'Pampa' type of CMS cytoplasm on yield and its related characteristics. For easy discrimination of male-sterile status of plants, anther scoring and the restore index system in which seed-setting and pollen quantity of viability were taken into account were established. High significant correlation between pollen quantity and pollen viability was found. For "Pampa" cytoplasm, four of 14 Korean inbred lines tested turned out to be a maintainer but no restorer was found. But for "235b" CMS cytoplasm, seven inbred lines acted as complete restorers. The Korean inbred rye lines acted mainly as maintainers in "Pampa" cytoplasm but acted mainly as restorer in "235b" cytoplasm. The 'Pampa' cytoplasm inducing male sterility reduced cohn length and plant height and increased the number of tiller, so forage yield and grain yield were enhanced. However, heading date was slightly delayed compared to the normal cytoplasm.elayed compared to the normal cytoplasm.

• Journal of Preventive Medicine and Public Health
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• 제52권2호
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• pp.101-108
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• 2019

Objectives: To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer. Methods: A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines. Results: Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations. Conclusions: Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.

• 대한토목학회논문집
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• 제28권5D호
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• pp.705-712
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• 2008

본 연구는 Fuzzy AHP기법을 의사결정의 방법론으로 이용하여 대형할인점의 입지선정을 위한 구조적이고 활용가능한 의사결정과정을 제시하고자 하였다. 이를 위해서 본 연구의 수행절차는 대형할인점의 입지선정을 위한 평가기준을 선정하여 평가기준간의 상대적인 가중치를 도출한 후, 사례대상지를 선정하고 입지를 실제로 평가하여 최적의 입지를 선정하는 두 단계로 구성된다. 평가기준간의 가중치에 있어서는 1차 상권인구가 가장 높은 가중치를 보였으며, 그 다음으로 경쟁업체수, 인접도로폭, 총인구수, 부지면적, 부지매입비의 순으로 가중치가 큰 것으로 나타났다. 또한 사례대상지인 대형할인점 부지 6개소의 입지현황을 파악하고 입지를 평가하여 최적의 입지를 도출함으로써 본 연구가 제시한 의사결정과정이 실제사례에 적용가능함을 입증하였다.

• 한국콘텐츠학회논문지
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• 제12권8호
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• pp.388-398
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• 2012

본 연구에서는 도시 하수관거시스템의 침수위험순위 평가를 위하여 엔트로피(Entropy) 기법 및 다기준 의사결정기법의 하나인 프로메티(Preference Ranking Organization METHod for Enrichment Evaluations, PROMETHEE)를 적용하였다. 엔트로피와 프로메티를 이용한 침수위험순위 산정에 있어서 평가 대상이 되는 항목들은 두 가지의 접근방식으로 선정되었다. 먼저 침수발생 및 피해 규모에 영향을 미치는 인자로 지형 환경적 요인으로써 유역의 평균고도, 평균경사, 유역폭, 인구수 및 관밀도를 선정하였다. 또한 각 시스템별 침수가 가장 크게 발생하는 초과강우사상을 선정 및 적용하여 시스템내 월류발생량 및 발생지점 두 가지를 이용한 치수안전성 지수를 추가적으로 고려하였다. 본 논문에서 적용된 엔트로피기법과 프로메티에 의한 도시 하수관거시스템 침수위험순위 평가는 추후 하수관거 정비사업의 계획 및 추진에 있어서 각 시스템별 위험도에 따른 개량우선순위 결정 및 평가지표로서 활용될 수 있을 것이다.

• Journal of Preventive Medicine and Public Health
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• 제34권3호
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• pp.183-190
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• 2001

Objective : To estimate the annual economic costs attributable to cigarette smoking in Korea. Methods : The costs were classified as being direct medical and non-medical costs, indirect costs and others. We focused on those costs related that are incurred in the treatment of selected diseases (cardiovascular diseases, respiratory diseases, and cancers), which have been proven to be caused by smoking. In addition to the basic costs of treatment, the additional amount of costs occurred due to smoking was obtained by computing the population attributable risk (PAR%) caused by smoking. To compute the PAR%, relative risks of smoking to the number of outpatient visits, hospitalizations, and the death were estimated using the Cox proportional hazard model, respectively. Our major data source was the 'Korea Medical Insurance Corporation (KMIC) cohort study,' which was composed of a total of 115,682 male and 67,932 female beneficiaries who had complete records of their smoking histories in the year of 1992. Results : The annual costs that could be attributable to smoking were estimated to be in the range of 2,847,500 million Won to 3,959,100 million Won. The maximum estimate of 3,959,100 million Won includes 233,100 million Won for medical costs, 5,100 million Won for transportation costs, 27,600 million Won for care giver's economic costs, 69,100 million Won in productivity loss, 3,435,000 million Won lost because of premature death, 172,100 million Won in costs resulting from passive smoke inhalation and 17,100 million Won for costs that resulted from fires that were caused by careless smoking. Conclusion : Our study confirms that the magnitude of the economic burden of smoking to Korean society is substantial. Therefore, this study provides strong evidence that there is a strong need for a national policy of tobacco control in Korea.