• Journal of Trauma and Injury
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• 제32권4호
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• pp.226-237
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• 2019

Purpose: This study investigated the characteristics of adult patients who had fallen from a height and presented to an emergency room (ER) according to gender and intentionality, with the goal of reducing the harm caused by these injuries. Methods: A retrospective analysis was conducted of fall-from-height patients aged ≥19 years from the in-depth surveillance study of injured patients visiting ERs conducted under the supervision of the Korea Centers for Disease Control and Prevention from 2011 to 2016. Patterns were analyzed according to gender and intentionality. Results: There were 29,838 men (68.5%) and 13,734 women (31.5%), with mean ages of 50.3±15.7 years and 57.2±19.9 years, respectively. The most common height of the fall was ≥1 m to 4 m in men (n=15,863; 53.2%) and <1 m in women (n=7,293; 53.1%). The most common location where the fall occurred was the workplace for men (n=10,500 male; 35.2%) and residential facilities for women (n=7,755; 56.5%). Most falls from height were unintentional (n=41,765; 97.1% vs. n=1,264; 2.9% for intentional falls). Suicide was the most frequent reason for intentional falls, and the age group of 19-30 years predominated in this category (n=377; 29.9%). For intentional falls, the most common interval before presentation to the ER was 0-6 hours (n=370; 29.3%) and the most common height was ≥4 m (n=872; 69.0%). Conclusions: Among men, falls from height most often occurred from ≥1 m to 4 m, at the workplace, and during the course of paid work, whereas among women, they were most common from <1 m, in residential facilities, and during daily activities. Intentional falls most often occurred with the purpose of suicide, in the age group of 19-30 years, with an interval of 0-6 hours until treatment, from ≥4 m, and in residential facilities. Alcohol consumption was more common in intentional falls.

• Clinical and Experimental Pediatrics
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• 제54권2호
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• pp.64-68
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• 2011

Purpose: The normal values for lung resistance and lung capacity of children, as determined by impulse oscillometry (IOS), are different for children of different ethnicities. However, reference values there is no available reference value for Korean preschool children have yet to be determined. The aim of the present study was to determine the normal ranges of IOS parameters in Korean preschool children. Methods: A total of 133 healthy Korean preschool children were selected from 639 children (aged 3 to 6 years) who attended kindergarten in Seongnam, Gyeonggi province, Korea. Healthy children were defined according to the European Respiratory Society (ERS) criteria. All subjects underwent lung function tests using IOS. The relationships between IOS value (respiratory resistance (Rrs) and reactance (Xrs) at 5 and 10 Hz and resonance frequency (RF)) and age, height, and weight were analyzed by simple linear and multiple linear regression analyses. Results: The IOS success rate was 89.5%, yielding data on 119 children. Linear regression identified height as the best predictor of Rrs and Xrs. Using stepwise multiple linear regressions based on age, height, and weight, we determined regression equations and coefficients of determination ($R^2$) for boys ($Rrs_5=1.934-0.009{\times}Height$, $R^2$=12.1%; $Xrs_5=0.774+0.006{\times}Height-0.002{\times}Age$, $R^2$=20.2% and for girls $(Rrs_5=2.201-0.012{\times}Height$, $R^2$=18.2%; $Xrs_5=-0.674+0.004{\times}Height$, $R^2$=10.5%). Conclusion: This study provides reference values for IOS measurements of normal Korean preschool children. These provide a basis for the diagnosis and monitoring of preschool children with a variety of respiratory diseases.

• 한국발생생물학회지:발생과생식
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• 제21권2호
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• pp.121-130
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• 2017

4-Nonylphenol (NP) is a surfactant that is a well-known and widespread estrogenic endocrine disrupting chemical (EDC). Although it has been known that the affinity of NP to ERs is low, it has been suggested that low-dose NP has toxicity. In the present study, the endocrine disrupting effects on reproduction, and the weight of gonads, epididymis, and uterus were evaluated with the chronic lower-dose NP exposing. This study was designed by following the OECD test guideline 443 and subjected to a complete necropsy. In male, NP had an effect on the weight of the testis and epididymis in both $F_0$ and $F_1$. In females, NP decreased the weight of ovary and uterus in $F_0$ but not in pre-pubertal $F_1$ pubs. Fertility of male and female in $F_0$ or $F_1$ was no related with NP administration. The number of caudal-epididymal sperm by body weight (BW) was not different between groups in both $F_0$ and $F_1$. Besides, the difference of the sperm number between generations was not detected. The number of ovulated oocytes was similar between groups in $F_0$, but significantly decreased in NP 50 group of $F_1$. The litter size and sex ratios of offspring in $F_1$ and $F_2$ were not different. The accumulated mating rate and gestation period were not affected by the NP administration. Those results shows that chronic lower-dose NP administration has an effect of endocrine disruptor on the weight of gonads and epididymis of $F_0$ and $F_1$ but not in reproduction. Based on the results, it is suggested that chronic lower-dose NP exposing causes endocrine disruption in the weight of gonad and epididymis but not in the reproductive ability of next generations.

• 한국환경농학회지
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• 제33권2호
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• pp.111-120
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• 2014

인천시내에 유통되는 오렌지, 키위 등 215건의 과일에 대하여 분석대상 농약 259종에 대한 잔류농약 모니터링을 실시하였다. 전체 수거 과일의 56.3%에서 기준이내 농약이 검출되었으며, 이중 수입과일은 60.8%, 국내산 과일은 45.1%의 검출률을 나타내었으나 농약잔류허용기준을 초과한 품목은 없었다. 그 중 감귤류의 농약 검출률은 83.9%로 상당히 높은 수준으로 나타났다. 농약성분별 검출빈도는 carbendazim(13.1%), imazalil(11.7%), thiabendazole(10.7%), fludioxonil(9.8%) 순으로, 검출된 농약의 위해성 평가결과 해당 농산물섭취에 따른 인체 유입 농약의 일일섭취추정량 ADI%는 0.00011~0.98795% 수준으로 위해성은 낮은 것으로 추정된다. 또한, 감귤류와 같은 과피를 제거 하고 섭취하는 과일은 과피 제거로 91.6%의 잔류농약 경감 효과를 나타내었으며, 세척 후 섭취하는 형태인 포도나 체리 등은 수돗물 침지 후 세척법에 의해서 평균 43.1%의 잔류농약 감소를 보여, 과일섭취에 따른 위해성 역시 상당부분 감소할 것으로 보인다.

• 한국수산과학회지
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• 제28권3호
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• pp.338-346
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• 1995

난태생 어류인 조피볼락(Sebastes schlegeli)의 성숙과 안정적인 출산을 위한 기초 정보를 얻고자, 간중량지수의 월별 변화와 간세포의 활성이 생식소의 발달과 어떤 관계에 있는지 조사하고, 아울러 생식소 발달에 따른 간 및 근육조직내의 단백질과 총 RNA 함량변화도 조사하였다. 암컷의 HSI는 9월부터 높아지기 시작하여 2월에 최대 값(2.58)에 달한 뒤, 3월(성숙기) 부터 5월(출산기) 사이에는 낮아졌다 수컷에서는 10월(성숙기)부터 높아지기 시작하여 4월(회복기)에 최대 값(3.20)에 달했다. 암컷의 난황형성기에 간세포내 글리코겐과 지방적의 양이 점차 감소되나, 총 RNA의 함량은 증가하였다. 그러나 수컷에서는 다량의 지방적들이 소모되지 않고 성숙기에도 세포질내에 잔존하고 있었다. 생식소의 발달과 함께 간 세포질에는 잘 발달된 조면소포체 가 증가하였는데, 이 들은 단백질 합성과 난황 전구물질의 형성에 중요한 역할을 하는 것으로 간주된다. 암컷의 간과 근육조직의 단백질 및 총 RNA 함량은 1월(성장기)부터 점차 증가되기 시작하여 4월 초순(성숙기)에 최대 값을 나타낸 다음, 4월 하순(임신기)에 감소되는 경향을 보였다. 수컷에서는 초기 성숙기인 10월부터 점차 증가하여 성숙 및 교미기인 12월에 최대 값을 보인 다음, 퇴화기인 1월에 다시 감소하였다.

• 복식
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• 제20권
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• pp.151-167
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• 1993

The purpose of this study is to systematize the theory of the Fashion Marketing and merchandi-sing system as well as the strategy for the Mar-keting based on the related variable. Furthermore, this study deals with development of the mark-eting strategy to the relation between consumers and industry. The content conclusion on the research can be outlined as follows : 1. In order to inverstigate how the life-style of consumers affects their sense of fashion, awa-reness of brand, and decision making process of purchase, the life-style of women consumers is classified into 15 types. (1) Acording to the different life-style types, and important difference is found in the consum-ers' sense of clothes, a unique image of outfit and its own favorite image of womanliness. (2) The consumer's awareness of a particular brand has a reasonable relationship with their brand preference and possession of the brands. (3) Their is an important discrimination acco-rding to the life-style types in their brand awar-eness and preference and possesion of brands. (4) The consumers of each life-style type show noticeable difference in the decision making pro-cess of purchase including he motive of purchase, the source of information, the cause of purchase intention, price, the frequency of purchase and the degree of satisfaction of purchased goods. 2. The merchandising system and the market positioning among the fashion industry are compared and analyzed in the following terms ; (1-1) For the purpose of establishing the target market strategy, the industry uses unreasenalbe methods to analyze the life-style of the target customers and the real customers(36%) and the aging phenomenon of brands is remarkable : as much as 37% of brands show over 5 years-old age gap. (1-2) The price setting process depends highly on the cost-plus approach. (1-3) In color planning, too many colors are used in every season(the average number is 22.3) and the investigation of the consumers' favorite color is neglected. (1-4) The manufacturers of successful brands are much likely to employ the textile designer and allow them to develop the various fabrication. (1-5) The regular rate of sales in each season is extremely low(56.04%) : the rate of the succ-essful brands is relatively high at 65%, but that of the unsuccessful as low as 51%. (1-6) 47% of brands reveal the designer-orie-nted fashion merchandising system. The successful brands, on the other hand, show a high rate of merchandiser oriented system. (2) Since the brand positioning is highly cen-tered on each brand image, styles and target age, the new data are presented in this study for the new market development. (3) To set up the target market, the mapping of images between the differentiated market and the consumers is suggersted according to the market positioning of industry and 15 types of the life-styles of consumers.

• 한국균학회지
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• 제23권2호통권73호
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• pp.153-160
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• 1995

담자균류의 하나인 잔나비걸상 자실체로부터 얻은 수성엑스의 항세균 시험과 항진균 시험을 액체배지 희석법으로 실시하고 naringenin과의 병용시험을 checkerboard assay 법으로 평가하였다. 항세균 시험결과 전반적으로 그람음성균보다 그람양성균에 대해 비교적 양호한 항균력을 나타내었으나 사용된 균주중 그람음성균인 Proteus vulgaris 78615는 MIC가 1.125 mg/ml로 가장 양호한 항균효과를 나타내었다. 11종의 균주에 대해 실시된 항진균 시험결과 Candida albicans, Fusarium spp. 그리고 Trichophyton mentagraphytes의 MIC가 7.5 mg/ml로 다른 균주에 대한 항진균 효과보다 두배 더 강한 효과를 나타내었다. naringenin과의 병용시험에서 Staphylococcus aureus ATCC 25923에 대하여 부분적 상승효과를 나타내었고, Klebsiella pneumoniae ATCC 10031과 Salmonella typhi ATCC 6229 두 균주에서 상가효과가 관찰되었다. 그리고 Bacillus subtilis ATCC 6633을 비롯한 7종의 균주에서 무관효과를 나타내었으며 길항효과는 관찰되지 않았다.

• 한국발생생물학회지:발생과생식
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• 제13권4호
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• pp.249-256
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• 2009

구조적으로 estrogen 수용체(estrogen receptor, ER)와 유사한 estrogen receptor-related receptor(ERR)는 포유동물에서 배발생 후기에 외배엽 형성과 관련되어 있다고 알려진 고아핵수용체(orphan nuclear receptor)이다. ERR은 ER과 DNA binding domain의 보존성은 유사하지만, ligand 결합 및 전사 활성은 다르다. 포유동물의 ERR에 관한 연구에 비하여 해양 무척추동물의 ERR에 대한 기능 연구는 매우 부족하다. 본 연구에서는 우리나라 동해안에 주로 서식하는 둥근성게(Strongylocentrotus nudus) ERR의 초기 발생기 유전자 발현 변화와 전사 활성 기능을 조사하기 위해 먼저 polymerase chain reaction(PCR)을 이용하여 cDNA를 동정하였다. 둥근성게 ERR은 S. purpuratus와 91%의 높은 상동성을 보였으며, 계통수 분석을 통해 무척추동물 ERR의 clade에 포함되는 것을 알았다. 둥근성게 배발생 시기에 ERR 유전자 발현을 알아보기 위하여 real-time PCR을 실시한 결과, 4~64세포기와 유생기에 mRNA level이 높은 경향을 나타내었다. 또한 호르몬 및 co-regulator에 의한 둥근성게 ERR의 전사 활성을 조사한 결과, 호르몬에 의한 특이성은 확인되지 않았지만, peroxisome proliferator activated receptor-(PPAR) $\gamma$ coactivator $1\alpha$(PGC-$1\alpha$)가 둥근성게 ERR의 coactivator임을 입증할 수 있었다. 이 연구 결과는 향후 새로운 ligand 발굴과 coregulator와 의 상호작용 연구에 도움이 될 것으로 사료된다.

• 한국환경농학회지
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• 제35권1호
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• pp.6-14
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• 2016

BACKGROUND: Residual organochlorine pesticides (OCPs) are chemical substances that persist in the environment, bioaccumulate through the food web, and pose a risk of causing adverse effect to human health and the environment. They were designated as persistent organic pollutants (POPs) by Stockholm Convention. Greenhouse strawberry is economic crop in agriculture, and its cultivation area and yield has been increased. Therefore, we tried to investigate the POPs residue in greenhouse soil and strawberry.METHODS AND RESULTS: Extraction and clean-up method for the quantitative analysis of OCPs was developed and validated by gas chromatography (GC) with electron capture detector (ECD). The clean-up method was established using the modified quick, easy, cheap, effective, rugged, and safe(QuEChERS) method for OCPs in soil and strawberry. Limit of quantitation (LOQ) and recovery rates of OCPs in greenhouse soil and strawberry were 0.9-6.0 and 0.6-0.9 μg/kg, 74.4-115.6 and 75.6-88.4%, respectively. The precision was reliable sincerelative standard deviation (RSD) percentage (0.5-3.7 and 2.9-5.2%) was below 20, which was the normal percent value. The residue of OCPs in greenhouse soil was analyzed by the developed method, and dieldrin, β-endosulfan and endosulfan sulfate were detected at 1.6-23, 2.2-28.4 and 1.8-118.6 μg/kg, respectively. Those in strawberry were not detected in all samples.CONCLUSION: Dieldrin, β-endosulfan and endosulfan sulfate in a part of investigated greenhouse soil were detected. But those were not detected in investigated greenhouse strawberry. These results showed that the residue in greenhouse soil were lower level than bioaccumulation occurring.

• 농약과학회지
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• 제16권2호
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• pp.151-162
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• 2012

본 연구에서는 분석대상 농약의 선정, 분석대상 식품의 선정, 분석대상 식품의 수집, 추출방법의 최적화를 통해 잔류농약 섭취 수준 평가를 위한 한국형 총식이섭취조사(Total Diet Study, TDS) 모델을 확립하였다. 또한 총식이섭취조사 모델 확립을 위해 필요한 각각의 항목에, 기준을 설정하여 확립된 모델에 의한 잔류농약 수준을 모니터링 하였다. 모니터링은 1단계에서는 총 102종의 대표식품, 2단계에서는 총 70종의 대표식품, 3단계에서는 12종의 대표식단과 109종의 대표식품을 대상으로 98종 농약에 대해 $GC-{\mu}ECD$, GC-MSD, 그리고 LC-MS/MS를 이용하여 분석을 실시하였다. 그 결과 검출된 농약들은 모두 잔류허용기준(Maximum Residue Limit, MRL) 이하의 잔류량을 보였으나 검출된 잔류농약이 해당 작물에 대해 잔류허용기준이 설정되어 있지 않은 경우도 있었다. 한국형 총식이섭취조사 모델을 확립함은 소비자들에게 안전한 먹거리 제공, 농산물의 안전성 확보 및 농산물 생산자들의 농약 사용에 대한 지속적인 정보 제공의 역할을 할 수 있는 자료를 제공하게 될 것이다.