• Journal of Information Technology Applications and Management
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• 제28권1호
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• pp.1-12
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• 2021

The purpose of this study is to analyze the medical ecosystem in the post-corona era. In addition, this study introduces a new medical CRM model that allows primary-level hospitals to overcome the economic difficulties and to occupy a competitive advantage in the post-corona era. The medical environment in the post-corona era is expected to be changed by non-face-to-face treatment, reinforcement of public medical care, the transformation of a medical system centered on the primary-level hospitals, and the use of AI and big data technologies. The medical CRM model presented in this study emphasizes the establishment of mutual customer relationships through close information exchange between patients, primary-level hospital, and the government. In the post-corona era, primary-level hospitals should not simply be approached as private hospital pursuing profitability. These should be reestablished as the hospitals that can provide public health care services while ensuring stable profitability.

• 한국철학논집
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• 제43호
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• pp.171-202
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• 2014

본 연구는 해방 이후 현대 교육의 이상적 인간상을 살펴보기 위하여 우선 해방 이후에서 90년대에 이르는 시기를 광복 이후 분단까지의 '전환기'와, 경제성장을 통한 현대 국가 발전의 기반이 된 '산업화 시기', 그리고 다양한 계층의 사람들이 정치?경제?사회 참여를 요구하는 '민주화 시기'의 세 시기로 구분하고, 각 시기의 특성에 대해 정치 경제 사회 문화 등 다양한 측면에서의 접근을 시도하였다. 특히, 교육적 인간상의 추출을 위하여 이들 각 시기의 주요 가치를 탐색함으로써 이와 관련한 각 시기별 인간상을 고찰하였다. 시기별로 나타나는 주요가치와 인재상은 다음과 같다. 전환기의 주요가치로는 예의와 규범을 제시할 수 있으며, 추구하는 인재상은 무실역행(務實力行)하는 자세가 강조되는 실천적 지식이었다. 산업화 시기의 주요가치로는 성실, 근면, 자조, 협동을 제시할 수 있으며, 추구하는 인재상은 경제발전에 필수적이고 강력한 직업능력을 갖춘 기능인이었다. 민주화의 주요가치로는 참여, 평등, 공존을 제시할 수 있으며, 추구하는 인재상은 경제성장의 둔화라는 위기감 속에서 국가의 생존과 번영을 위하여 이바지하는 우수한 과학인재상이었다. 각 시기별 인재상은 실용적이면서도 실천적인 유형의 인간상이 드러나고 있으며 공동체적 덕성을 중시하고 있는데, 이는 전통적인 가치관의 연속선상에서 시기별 특징을 보여주고 있는 대목이기도 하다.

• 한국가구학회지
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• 제23권2호
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• pp.122-129
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• 2012

This article was intended as fundamental materials to recognize the current status of furniture hard ware in Korean market and to fix the identity of Korean furniture, by investigating and comparing the furniture hard ware used in the Joseon era and in modern times by type, function, shape and material. The analysis of furniture hard ware of the Joseon era and modern times from the view of functional aspects was oriented to the hard ware necessary to open and close the door & drawer on one side, and to that being attached to the main body of furniture not to scratch the wood by another wood on the other side, and from this the following conclusion was drawn. First of all, "Gwangdoojung" - a kind of spike- and metal decoration on the edge of the furniture disappeared, while the function-oriented hard wares have been diversified in modern times, from the perspective of the change of kinds. Second, the functional aspect of the furniture hard ware was emphasized in modern times than the Joseon era. In other words, the hard wares of the Joseon era came into view due to their strong appeal to decoration, whereas those of modern times were mostly hidden or moderated, keeping the function substantially. Third, the hard wares from the Joseon era were shown in concrete and detailed shape motivated by natural objects and furthermore even gloriously, but the modern hard wares are simple & basic geometry, from a formative point of view. Fourth, the material aspects present that the Joseon era's hard ware was mainly cast iron, whereas that of modern times shows the diversification from metal to even plastic. Finally, the recent trend in naming of the hard wares is the words of foreign origin. This resulted from that the foreign names of hard wares are valid also after import process in Korean market, so the domestic development of hard ware as the essential factor for the furniture design is urgently necessary to establish the identity of Korean modern furniture.

• 대한간호학회지
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• 제45권1호
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• pp.14-24
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• 2015

Purpose: The purpose of this study was to measure the level of expectations regarding aging (ERA) and identify relationship between ERA and physical activity of middle aged adults. Methods: Participants were middle aged adults who resided in the community in three cities in Korea. Data were collected using questionnaires that contained items on individual characteristic, International Physical Activity Questionnaires (IPAQ), and behavior-specific cognitive factors including ERA-12. Hierarchical multiple regression was conducted to examine whether ERA would predict physical activity by controlling other factors. Results: The mean age of the participants was $51.1{\pm}6.9$ years. The mean score for ERA (possible range=0 to 100) was $40.04{\pm}14.31$. More than half of the participants (62.6%) were not engaged in health promoting physical activity. Gender, employment status and exercise confidence were associated with level of physical activity (F=7.14, p<.001, $R^2=.36$). After controlling for individual factors and behavior-specific cognitive factors, ERA was independently related to physical activity (F=7.19, p<.001, $R^2=.38$). Conclusion: The results demonstrate that individuals' belief about aging has effects on physical activity in Korean middle aged adults. Thus, nursing interventions which focused on ERA could help enhance physical activity in middle aged adults.

• Journal of Microbiology and Biotechnology
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• 제33권8호
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• pp.1091-1100
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• 2023

Human papillomavirus (HPV) types 16 and 18 are the major causes of cervical lesions and are associated with 71% of cervical cancer cases globally. However, public health infrastructures to support cervical cancer screening may be unavailable to women in low-resource areas. Therefore, sensitive, convenient, and cost-efficient diagnostic methods are required for the detection of HPV16/18. Here, we designed two novel methods, real-time ERA and ERA-LFD, based on enzymatic recombinase amplification (ERA) for quick point-of-care identification of the HPV E6/E7 genes. The entire detection process could be completed within 25 min at a constant low temperature (35-43℃), and the results of the combined methods could be present as the amplification curves or the bands presented on dipsticks and directly interpreted with the naked eye. The ERA assays evaluated using standard plasmids carrying the E6/E7 genes and clinical samples exhibited excellent specificity, as no cross-reaction with other common HPV types was observed. The detection limits of our ERA assays were 10⁰ and 10¹ copies/µl for HPV16 and 18 respectively, which were comparable to those of the real-time PCR assay. Assessment of the clinical performance of the ERA assays using 114 cervical tissue samples demonstrated that they are highly consistent with real-time PCR, the gold standard for HPV detection. This study demonstrated that ERA-based assays possess excellent sensitivity, specificity, and repeatability for HPV16 and HPV18 detection with great potential to become robust diagnostic tools in local hospitals and field studies.

• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2003년도 가을학술발표대회
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• pp.34-35
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• 2003

• 한국지구과학회지
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• 제41권2호
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• pp.95-110
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• 2020

본 연구에서는 고해상도 ERA5 재분석자료 중 우리나라 지상 온도 자료의 신뢰성을 검증할 목적으로 종관기상관측소(ASOS) 관측자료와 비교를 수행하였다. 새롭게 생산되어 배포 중인 ERA5 재분석자료는 높은 시·공간적 해상도를 가져 여러 분야에 활용성이 매우 높다. 자료의 분석 기간은 ASOS 61개 관측소가 1999년 이후로 결측률이 매우 낮으며 시간평균 자료를 제공한다는 점을 고려하여 1999-2018년 기간으로 설정하였다. ERA5 격자 자료는 격자 내 90-m 수치표고모델(DEM) 분포로부터 내륙, 해안, 산악 지역에 해당하는 지형학적인 특성에 따라 분류하여 ASOS 지점 자료와 비교되었다. 분석 기간 전체에 대한 평균 지상 온도는 ASOS와 ERA5 모두 공간 분포의 패턴과 값은 큰 차이없이 유사하였다. ASOS와 ERA5의 산점도 비교를 통해 전체 기간, 특히 여름, 겨울 기간에 대해 계절 변동성을 가진다는 특성을 확인할 수 있었으며, 이는 달별 두 자료 사이의 매시간 차이 확률밀도함수(PDF)의 시계열을 통해서도 확인되었다. 두 자료 사이의 차이를 통계지수인 NMB, RMSE를 계산하여 정량화시켰을 때, 각 값에서 지역적인 특성을 보였으나 모든 지수에서 큰 차이가 없다고 판단할 수 있었으며, 상관성을 보기 위해 R과 IOA를 통해 구한 값은 모두 0.99에 근접하였다. 특히 일평균 산출에 있어 1-시간-평균 값 24개를 이용한 일평균의 경우가 최고와 최저온도의 평균을 이용하는 일평균에 비해 오차가 작게 나타났고, 두 자료 사이의 상관성도 높게 나타남을 확인하였다. 두 자료의 차이가 나타나는 원인으로 ERA5 격자 내 지형 효과가 가장 클 것으로 판단하여 수치표고모델을 활용하여 각 지역별 PDF를 이용해 첨도 및 왜도를 구하고, 이를 온도 차이 파워 스펙트럼의 1년 주기 변동 크기와 비교하였다. 그 결과, 양의 상관성을 가졌음을 확인하였다. 이는 지형 효과가 두 자료 차이의 원인이라고 설명하는 결과이다.

• 한국자원식물학회지
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• 제31권2호
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• pp.102-108
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• 2018

본 연구는 꼭두서니의 뿌리인 천초근의 물 추출물과 에탄올 추출물을 이용하여 대장암 세포에 대한 암세포 성장 억제 및 사멸효과가 있는지 알아보고자 수행하였다. ERA(천초근 에탄올 추출물)은 폴리페놀($45.77{\pm}2.03mg/g$)과 플라보노이드($22.82{\pm}1.33mg/g$)를 함유하고 있었으며, $H_2O_2$에 의해 증가된 ROS(reactive oxygen species)를 억제하는 효과를 나타냈지만 WRA(천초근 물 추출물)은 효과가 없었다. 또한 ERA는 $500{\mu}g/m{\ell}$의 농도로 대장암 세포주(HCT-116)에 처리했을 때 세포사멸을 유도할 뿐만 아니라 caspase-3 단백질 활성화, DNA fragmentation 및 apoptotic cell death를 일으키는 것으로 확인되었다. 이는 ERA가 HCT-116 세포주에 대해 apoptosis(세포자멸사)를 통해 항암효과를 나타내는 것으로 생각되지만 다른 연구결과들과 비교하였을 때 농도 대비 효능이 미미하다. 따라서 천초근 에탄올 추출물에 대장암 세포의 성장을 억제하는 유효성분을 분석하여 그 효능을 탐색하는 추가실험이 필요할 것으로 생각된다.

• Structural Engineering and Mechanics
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• 제63권6호
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• pp.743-750
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• 2017

Modal parameter identification plays a key role in the structural health monitoring (SHM) for civil engineering. Eigensystem realization algorithm (ERA) is one of the most popular identification methods. However, the complex environment around civil structures can introduce the noises into the measurement from SHM system. The spurious modes would be generated due to the noises during ERA process, which are usually ignored and be recognized as physical modes. This paper proposes an improved stabilization diagram method in ERA to distinguish the spurious modes. First, it is proved that the ERA can be performed by any two Hankel matrices with one time step shift. The effect of noises on the eigenvalues of structure is illustrated when the choice of two Hankel matrices with one time step shift is different. Then, a moving data diagram is proposed to combine the traditional stabilization diagram to form the improved stabilization diagram method. The moving data diagram shows the mode variation along the different choice of Hankel matrices, which indicates whether the mode is spurious or not. The traditional stabilization diagram helps to determine the concerned truncated order before moving data diagram is implemented. Finally, the proposed method is proved through a numerical example. The results show that the proposed method can distinguish the spurious modes.

• 동력기계공학회지
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• 제20권4호
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• pp.44-51
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• 2016

An investigation on reliability of reanalysis wind data was conducted using the met mast wind data at four coastal regions, Jeju Island. Shinchang, Handong, Udo and Gangjeong sites were chosen for the met mast sites, and ERA-Interim and MERRA reanalysis data at two points on the sea around Jeju Island were analyzed for creating Wind Statistics of WindPRO software. Reliability of reanalysis wind data was assessed by comparing the statistics from the met mast wind data with those from Wind Statistics of WindPRO software. The relative error was calculated for annual average wind speed, wind power density and annual energy production. In addition, Weibull wind speed distribution and monthly energy production were analyzed in detail. As a result, ERA-Interim reanalysis data was more suitable for wind resource assessment than MERRA reanalysis data.