• Title/Summary/Keyword: ER effect

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Electrorheological Properties of Anhydrous ER Suspensions Based on Phosphated Cellulose (인산처리 셀룰로오스를 첨가한 비수계 ER 유체의 전기유변학적 특성)

  • 안병길;최웅수;권오관;문탁진
    • Tribology and Lubricants
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    • v.14 no.2
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    • pp.1-9
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    • 1998
  • The electrorheological (ER) behavior of suspensions in silicone oil of phosphated cellulose particles (average particle size 17.77 ${\mu}{\textrm}{m}$) was investigated at room temperature with electric fields up to 2.5 KV/mm. In this paper, for development of anhydrous ER suspensions using at wide temperature range, we would like to know fundamental understandings on the ER activity. As a first step, the anhydrous ER suspensions dispersed the phosphated cellulose particles were measured, and not only the electrical characteristics such as dielectric constant, current density and electrical conductivity but also the rheological properties on strength of electric field and quantity of dispersed phase were studied. From the experimental results, the anhydrous ER suspensions dispersed phosphated cellulose particles showed a stable current density and very high performance of ER effect $(\tau/\tau_0=1030)$ on the 2.5 KV/mm and the dynamic yield stress $(\tau_y)$ was in exponential proportion to the strength of electric fields.

Investigation of Mechanical Characteristics of ER Fluids for Application in Hydraulic Valve (유압밸브 적용을 위한 ER 유체의 역학적 특성 고찰)

  • 김옥삼;이현창;박우철
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.10 no.4
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    • pp.84-90
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    • 2001
  • The electro-reheoligical(ER) effect refers to the abrupt change in viscosity in certain suspensions on application of an electric field. This paper presents experimental results on material properties of an ER fluids subjected to electrical fatigues. As a first step, two types of EF fluids are made of arabic gum and methyl cellulose(MC) choosing 25% of parti-cle weight-concentration. Following the construction of test mechanism for electrical durability of ER fluid, the dynamic yield shear stress and current density of the ER fluids are experimentally distilled as a function of electric field. The yield shear stress of operated ER fluids are distilled and compared with those of unused ER fluids.

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Regulation of Estrogen Receptor Under Hypoxia in Breast Cancer Cells

  • Lee, Young-Joo
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2008.04a
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    • pp.55-74
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    • 2008
  • Previously, we have shown that hypoxia, through HIF-1, induces ligand-independent $ER{\alpha}$ activation and the physical interaction of HIF-1 and $ER{\alpha}$. However, the effect of hypoxia on the transactivation of $ER{\beta}$ is not yet known. In the present study, we found that hypoxia activated the $ER{\beta}$-mediated transcriptional response in the HEK 293 cell line, as determined by the transient expression of$ER{\beta}$ and ER-responsive reporter plasmids. The hypoxia-induced estrogen response element-mediated transcriptional response was dependent on $ER{\beta}$ expression and was inhibited by the ER antagonist ICI 182,780. Transactivation of $ER{\beta}$ was induced by the expression of HIF-$1{\alpha}$ under normoxic conditions, as determined by the expression of oxygen-independent stable GFP-HIF-$1{\alpha}$. HIF-$1{\alpha}$-induced $ER{\beta}$ transactivation was abolished by the inhibition of HIF-$1{\alpha}$ activation. This was determined by using chemical inhibitors for the MAPK pathway. In addition, HIF-$1{\alpha}$ interacted with $ER{\beta}$ in a mammalian-two hybrid assay. We conclude that hypoxia activates $ER{\beta}$ in a ligand-independent manner, possibly through the interaction of HIF-$1{\alpha}$ and $ER{\beta}$.

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Evaluation of Apparent Viscosity Properties for Electro-Rheological Fluid (ER유체의 겉보기 점도특성 평가에 관한 연구)

  • ;Morishita, Shin
    • Tribology and Lubricants
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    • v.14 no.2
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    • pp.42-48
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    • 1998
  • Electro-Rheological (ER) fluid is a class of functional fluid whose apparent viscosity can be varied by the applied electric field strength. The ER fluid is classified into two types; one is a dispersive fluid and the other is a homogeneous. Dispersive ER fluid is a colloidal suspension of fine semiconducting particles in a dielectric liquid and liquid crystal (LC) is classed as homogeneous type ER fluid. LC has been originally developed for some electronic display devices. Various mechanical components applying ER fluid have been developed, and the their performance typically depends on the characteristics of ER fluid which have generally been evaluated by a rotational viscometer. However, the ER fluid introduced into various mechanical components undergoes not only simple shear flow but press flow or oscillating flow. For the evaluation of ER fluid, the authors developed an reciprocating type viscometer. The amplitude is controlled on 5 mm at the frequency from 50 to 1000 Hz. In the present paper, the performance of several types of ER fluid is evaluated by the reciprocating type viscometer and compared with those evaluated by a rotational viscometer.

Separating nanocluster Si formation and Er activation in nanocluster-Si sensitized Er luminescence

  • Kim, In-Yong;Sin, Jung-Hun;Kim, Gyeong-Jung
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.109-109
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    • 2010
  • $Er^{3+}$ ion shows a stable and efficient luminescence at 1.54mm due to its $^4I_{13/2}\;{\rightarrow}\;^4I_{15/2}$ intra-4f transition. As this corresponds to the low-loss window of silica-based optical fibers, Er-based light sources have become a mainstay of the long-distance telecom. In most telecom applications, $Er^{3+}$ ions are excited via resonant optical pumping. However, if nanocluster-Si (nc-Si) are co-doped with $Er^{3+}$, $Er^{3+}$ can be excited via energy transfer from excited electrical carriers in the nc-Si as well. This combines the broad, strong absorption band of nc-Si with narrow, stable emission spectra of $Er^{3+}$ to allow top-pumping with off-resonant, low-cost broadband light sources as well as electrical pumping. A widely used method to achieve nc-Si sensitization of $Er^{3+}$ is high-temperature annealing of Er-doped, non-stoichiometric amorphous thin film with excess Si (e.g.,silicon-rich silicon oxide(SRSO)) to precipitate nc-Si and optically activate $Er^{3+}$ at the same time. Unfortunately, such precipitation and growth of nc-Si into Er-doped oxide matrix can lead to $Er^{3+}$ clustering away from nc-Si at anneal temperatures much lower than ${\sim}1000^{\circ}C$ that is necessary for full optical activation of $Er^{3+}$ in $SiO_2$. Recently, silicon-rich silicon nitride (SRSN) was reported to be a promising alternative to SRSO that can overcome this problem of Er clustering. But as nc-Si formation and optical activation $Er^{3+}$ remain linked in Er-doped SRSN, it is not clear which mechanism is responsible for the observed improvement. In this paper, we report on investigating the effect of separating the nc-Si formation and $Er^{3+}$ activation by using hetero-multilayers that consist of nm-thin SRSO or SRSN sensitizing layers with Er-doped $SiO_2$ or $Si_3N_4$ luminescing layers.

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Comparison of Phenol Removal between Electrochemical Reaction and Plasma Reaction

  • Kim, Dong-Seog;Park, Young-Seek
    • Journal of Environmental Science International
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    • v.25 no.7
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    • pp.905-916
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    • 2016
  • The characteristics of phenol removal and $UV_{254}$ matters variance were investigated and compared by the variation of operating factors (NaCl concentration, air flow rate, initial phenol concentration) in electrochemical reaction (ER) and dielectric barrier discharge plasma reaction (DBDPR), respectively. The phenol removal rate was shown as $1^{st}$ order both in ER and DBDPR. Also, the absorbance of $UV_{254}$ matters which means aromatic intermediates was analyzed to investigate the complete phenol degradation process. In ER, the phenol degradation and aromatic intermediates production rates increased by the increase of NaCl concentration. However, in DBDPR, the variation of NaCl concentration had no effect on the degradation of phenol and $UV_{254}$ matters. Air flow rate had a little effect on the removal of phenol and the variation of $UV_{254}$ matters in ER. The phenol removal rate in ER was a little higher than that in DBDPR. The produced $H_2O_2$ and $O_3$ amounts in ER were 2 times and 10 times higher than those in DBDPR. The chlorine intermediates ($ClO_2$ and free chlorine) were produced in ER, however, they were not produced in DBDPR.

Experimental Investigation on the Flow Characteristics of ER Fluids II (2nd Report, Viscosity-Temperature Characteristics of Dispersive ER Fluids) (ER 유체의 유동특성에 관한 실험적 연구 II (분산계 ER 유체의 점도-온도 특성))

  • 김도태
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 1999.10a
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    • pp.393-398
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    • 1999
  • The temperature dependence of the viscosity was determined for an electrorheological(ER) fluid consisting of 35 weight% zeolite particles in hydraulic oil 46cSt. Thermal activation analysis were performed by changing the ER fluid's temperature from -1$0^{\circ}C$ to 5$0^{\circ}C$ at fixed electric field. According to the analysis, the activation energy for flow was about 79.64kJ/mole at E=0kV/mm. Generally, the hydraulic oil 46cSt will be operated at the temperature of about 4$0^{\circ}C$, the ER fluid's electric field dependence of viscosities were investigated at this temperature. also, the influence of adding the dispersant(Carbopl 940) on electrorheological effect of the ER fluid was discussed.

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ANTICANCER EFFECT OF TAMOXIFEN IN ORAL CANCER CELL (구강암세포주에서의 Tamoxifen의 항암효과)

  • Jung, Jae-Hwa;Yun, Pil-Young;Myoung, Hoon;Shin, Jae-Il;Lee, Jong-Ho;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.29 no.6
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    • pp.365-373
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    • 2003
  • Tamoxifen is an selective estrogen receptor antagonist widely used in the management of patients with breast cancer for more than 30 years. It was thought to act primarily through occupying the estrogen receptor sites in ER positive breast cancer cells and directly on cancer cell proper. These inhibitory effects, which have been shown to be independent of the ER, highlight new mechanism of therapeutic action of tamoxifen. The purposes of this study were to identify ER in oral carcinoma cell lines and to evaluate ER independent cytotoxic effect of tamoxifen. KB(SCC), HSC-3(SCC) and A253(ACC) cell line were used and capacity of cell proliferation, apoptosis, in vitro invasion and gelatin zymography were tested. ER expression of each cell line were detected by RT-PCR and immunocytochemistry. Dose dependent inhibition of cell proliferation and inhibition of gelatinolytic activity were observed in all oral carcinoma cell lines and significant difference of apoptotic index were observed in A253 and KB. Tamoxifen inhibited in vitro invasion in all experimental groups. ER expression was detected in KB and A253. These data suggest that tamoxifen may play a role in management of oral carcinoma by independent cytotoxic effect and more advanced research must processed confirming ER-dependent cytotoxicity.

Effect of Additive Composition on Mechanical Properties of Silicon Carbide Sintered with Aluminum Nitride and Erbium Oxide

  • Lee, Sung-Hee;Kim, Young-Wook
    • Journal of the Korean Ceramic Society
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    • v.42 no.1
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    • pp.16-21
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    • 2005
  • The effect of additive composition, using AlN and $Er_{2}O_{3}$ as sintering additives, on the mechanical properties of liquid-phase-sintered, and subsequently annealed SiC ceramics was investigated. The microstructures developed were quantitatively analyzed by image analysis. The average thickness of SiC grains increased with increasing the $Er_{2}O_{3}/(AlN + Er_{2}O_{3})$ ratio in the additives whereas the aspect ratio decreased with increasing the ratio. The mechanical properties versus $Er_{2}O_{3}/(AlN + Er_{2}O_{3})$ ratio curve had a maximum; i.e., there was a small composition range at which optimum mechanical properties were realized. The best results were obtained when the ratio ranged from 0.4 to 0.6. The flexural strength and fracture toughness of the SiC ceramics were $550\~650\;MPa$ and $5.5\~6.5$ MPa${\cdot}m^{1/2}$, respectively.

Vibration Control of Rotor Systems Using ER Effect (ER 효과를 이용한 회전축계의 진동제어)

  • Lim, Seung-Chul;Park, Sang-Min;Chae, Jeong-Jae
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2000.06a
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    • pp.1119-1126
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    • 2000
  • This paper is concerned with the design and application of an Electro-Rheological(ER) fluid damper to suppress the vibration of a rotor system. The system is flexible with a slender shaft and a thin disk, being supported by two ball bearings. In addition, to investigate the system performances also in the high speed range, the driving torque is made transmit through a speed increasing gear train. Along with the experiments, to predict and compare the ER damper effect, the rotor system is simulated as to its free and forced vibration characteristics by means of a finite element method code, which is assembled with the mathematical model of the designed ER damper.

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