• 한국지능시스템학회논문지
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• 제10권6호
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• pp.542-547
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• 2000

진화프로그래밍(Evolutionary Programming : EP)은 최적화 문제에 있어서 매우 유용한 기법으로 자연선택의 원리를 모방한 탐색알고리즘이다. EP는 기존의 최적화 알고리즘에 비하여 여러해를 동시에 탐색하는 전역탐색(global search)방법이므로 국부수렴(local convergence)의 가능성이 줄어들고, 최적화 파라메터 영역의 연속성과 미분치의 존재성과 같은 조건이 필요 없는 장점을 갖는다. 이러한 장점에도 불구하고, EP의 탐색영역이 초기조건 및 최적화 파라메터들의 랜덤 생성 그리고 최적화에 필요한 전략적 파라메터들에 의하여 탐색 영역이 결정되고, 수렴성이 느린 단점을 갖는다. 이러한 문제를 해결하기 위하여, 본 연구에서는 빠른 수렴성과 다양성을 갖는 개선된 EP을 제안하고, 제안된 방향성 벡터를 갖는 개선된 EP를 함수 최적화 문제에 적용하여 그 성능의 유용성을 보이고자 한다.

• 한국양식학회지
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• 제18권2호
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• pp.98-106
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• 2005

본 연구는 지질과 단백질 함량이 다른 두 종류 부상사료의 적정 공급횟수와 공급율을 조사하기 위해 평균 체중 55.1 g의 넙치를 각 수조마다 20마리씩 3반복으로 수용하여 58일 동안 사육하였다. 사료공급휫수는 1일 3회, 1일 2회 및 1일 1회로 설정하였으며 사료 공급량은 만복 및 만복의 80%로 각각 설정하였다. 생존율은 모든 실험 구에서 82% 이상이였으며, 평균 증중량은 EP1의 1일 2회 만복 공급구가 가장 높은 증중량을 보였으며, EP1의 1일 2회 및 3회 제한 공급구와 EP2의 1일 2회 제한 공급구가 가장 낮았다. 일일사료섭취율은 EP1의 1일 2회와 1일 3회 만복 공급구가 가장 높았고, EP2의 1일 3회 만복 공급구와 유의한 차이가 없었다(P>0.05). 사료효율과 단백질효율은 사료 조성, 공급횟수 및 공급을 모두 영향을 받지 않았다(P>0.05). 사육실험 종료시, 근육의 수분 함량은 동일한 사료와 공급휫수에서 제한 공급구가 만복 공급구에 비해 높았다. 이상의 결과들로 보아 평균체중 $55{\sim}90g$인 넙치의 성장을 위해 EP1과 EP2를 1일 2회 만복으로 공급하는 것이 적합할 것으로 판단된다.

• Neonatal Medicine
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• 제18권2호
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• pp.387-390
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• 2011

식도천공은 신생아에서 드문 질환이다. 그러나 영양관 삽관으로 인한 의인성 식도천공은 미숙아에서는 특히 드물지 않게 나타난다. 의인성 식도천공은 기흉같은 심한 합병증을 유발하며 사망을 일으킬 수 있다. 일반적으로 식도천공의 결과로 기흉이 발생하는 것으로 알려져있다. 반면에, 저자들은 기흉이 먼저 병발하고 이 후 의인성으로 발생한 식도천공을 경험하였다. 증례의 식도천공은 환아에게 기흉이 발생한 채로 영양관을 삽관하여 야기되었다. 기흉이 있는 상태에서 영양관 삽관을 고려할 때는 더 심사숙고 하여야 할 것이다.

• 수산해양교육연구
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• 제25권6호
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• pp.1315-1323
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• 2013

The purpose of this research is to evaluate the effects of a commercial mixed extruded pellet(EP) and raw fish moist pellet(MP) diet on diseases prevalence and serological constituents and HSI of korean rockfish, Sebastes schlegeli grown in two commercial-scale aquaculture farms from June to December in 2009. The growth of MP-fed rockfish was slightly faster than EP-fed rockfish during experimental period, but did not show significant differences. The levels of TCHO, TG, Glucose and TP in the MP-fed rockfish group were higher than those of EP-fed group, whereas there was no significant difference in other biochemical factors of blood between two groups. In addition, bacteria and virus were not detected in both MP- and EP-fed rockfish groups, and the infection rates of gill fluke between two groups did not show clear difference. In conclusion, there was no comparable difference in growth and the health extents of one year rockfish by administration of the commercial mixed extruded pellet(EP) and raw fish moist pellet(MP) diets.

• Asian-Australasian Journal of Animal Sciences
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• 제17권5호
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• pp.617-620
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• 2004

The present study compares development of rabbit embryos generated using different oocyte activation protocols and reconstructed with embryonic or cumulus cells as nuclear donor. In vivo matured oocytes were collected from New Zealand White rabbits at 16 h after ovulation treatment and were activated at18 h of post-ovulation treatment. The following schemes of oocytes activation were tested: 1) single electric pulse (EP, 3.2 kV/cm, 3${\times}$20 $\mu$s, 0.3 M mannitol)+5 min culture in the presence of 5 mM Ionomycin, 2) single electric pulse (EP, 3.2 kV/cm, (${\times}$20 $\mu$s, 0.3 M mannitol)+1 h culture in the presence of 2 mM 6-DMAP, and 3) three electric pulses 30 min apart. Cleavage rate, percentage of expanded and hatched blastocysts as well as total cell number of blastomeres of parthenogenetic embryos were significantly higher using either EP+6-DMAP or 3${\times}$EP schemes, comparing with EP+Ionomycin. Development rate up to hatched blastocyst stage of cloned rabbit embryos using the EP+6-DMAP for activation of nuclei were 19% for embryonic cell nuclei and 36% for cumulus cell nuclei. The best activation protocol optimalized in this study was the combined treatment "P+6-DMAP" which may be potentially used for nuclear transfer protocol.

• 한국수산과학회지
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• 제47권6호
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• pp.785-789
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• 2014

An experiment was conducted to investigate the effects of feeding by different feed types (powder, crumble and pellet) of two different feed formulations with simple dried (D) or extruded (E) conditions on growth and body composition of juvenile sea cucumber Apostichopus japonicus. Triplicate groups of sea cucumber averaging $1.2{\pm}0.05g$ were fed each of the D1, D2, EP1 or EP2 diets for 12 weeks. Survival of sea cucumber fed D2-crumble was higher than that fed EP2-crumble diet (P<0.05). Weight gain of sea cucumber fed EP1-powder was higher than that fed EP1-crumble and EP2-crumble diets (P<0.05). These findings indicated that simple dried feed could use independently feed type for sea cucumber culture and powder type of extruded feed is also good for sea cucumber culture.

• KIEAE Journal
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• 제16권2호
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• pp.11-16
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• 2016

Purpose: International efforts to save Earth's environment against global warming and environmental pollution have been made in many countries. Energy consumption of buildings has been continuously increasing, and it has been over 40% of total energy consumption in the world. Energy consumption of buildings in Korea reaches 24% of total energy consumption. So, Korea government has executed building energy rating systems to control energy consumption of buildings. Method: This study was carried out to evaluate the energy performance of apartment unit plans according to converting balconies into living areas. For the study, six types of input models were made. Two input models(SP1 and SP 2) were the standard units that balcony areas were not converted into living areas, and four ones(EP 1, EP 2, EP 3 and EP 4) were the extended unit plans that balcony areas were turned into living areas. All of them were simulated with ECO2 software to assess building energy efficiency. Result: According to the results, the energy performance of the EP 2 and EP 4 models were 21. 8% higher than SP 1 model and 9.2% higher than SP 2 model.

• Advanced Composite Materials
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• 제18권3호
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• pp.221-232
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• 2009

The allylamine plasma treatment is used to modify the surface properties of vapor grown carbon fibers (VGCF). It is to improve the interfacial bonding between the VGCF and epoxy matrix. The allylamine plasma process was performed by batch process in a vacuum chamber, using gas injection followed by plasma discharge for the durations of 20, 40 and 60 min. The interdependence of mechanical properties on the VGCF contents, treatment time and interfacial bonding between VGCF/ep was investigated. The interfacial bonding between VGCF and epoxy matrix was observed by scanning electron microscopy (SEM) micrographs of nanocomposites fracture surfaces. The changes in the mechanical properties of VGCF/ep, such as the tensile modulus and strength were discussed. The mechanical properties of allylamine plasma treated (AAPT) VGCF/ep were compared with those of raw VGCF/ep. The tensile strength and modulus of allyamine plasma treated VGCF40 (40 min treatment)/ep demonstrated a higher value than those of other samples. The mechanical properties were increased with the allyamine plasma treatment due to the improved adhesion at VGCF/ep interface. The modification of the carbon nanofibers surface was observed by transmission electron microscopy (TEM). SEM micrographs showed an excellent dispersion of VGCF in epoxy matrix by ultrasonic method.

• Molecules and Cells
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• 제37권10호
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• pp.742-746
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• 2014

The epithelial cell adhesion molecule (EpCAM, also known as CD326) is a transmembrane glycoprotein that is specifically detected in most adenocarcinomas and cancer stem cells. In this study, we performed a Cell systematic evolution of ligands by exponential enrichment (SELEX) experiment to isolate the aptamers against EpCAM. After seven round of Cell SELEX, we identified several aptamer candidates. Among the selected aptamers, EP166 specifically binds to cells expressing EpCAM with an equilibrium dissociation constant (Kd) in a micromolar range. On the other hand, it did not bind to negative control cells. Moreover, EP166 binds to J1ES cells, a mouse embryonic stem cell line. Therefore, the isolated aptamers against EpCAM could be used as a stem cell marker or in other applications in both stem cell and cancer studies.

• 미생물학회지
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• 제36권1호
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• pp.64-68
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• 2000

Agrocybe cylindracea으로부터 분리 배양한 균사체 배양액을 이용하여 균사체내 다당류(IP)와 균사체외 다당류(EP)를 분리하고, 동물실험을 통한 각 다당류의 면역증강활성에 관해 실험을 실시하였다. 탐식능에 대한 실험결과, IP와 EP 모두는 복강 침출 세포(PEC)에서 대조군에 비해 6.6-50%, 말초 임파구(ML)에서 67-167%, 비장(SP)에서 16-90%의 전반적으로 높은 탐식능을 나타냈다. 또한 항체 생성능 측정을 위한 plaque forming cell(PFC)와 rosette forming cell(RFC)의 실험결과에서 볼 때, PFC형성능은 대조군에 비해 EP투여 II군에서 46-50%, IP투여 I군에서 49-70%의 활성증가를 나타내었다. 또한 RFC형성능은 대조군에 비해 IP투여 I군에서 91%의 증가를, EP투여 I군에서 33%, EP투여 II군에서 43%의 활성증가를 나타내어 높은 항체생성이 기대되었다. Mitogen 활성은 농도 의존적으로 세포 증식능을 보였으며, IP와 EP를 비교할 때, EP는 IP에 비해 약2.5배의 세포증식 활성을 보였다.