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Intraoperative Neurophysiologic Monitoring and Functional Outcome in Cerebellopontine Angle Tumor Surgery (소뇌-교각종양 수술시 수술 중 전기생리학적 신경감시에 따른 수술 후 기능적 결과)

  • Lee, Sang Koo;Park, Kwan;Park, Ik Seong;Seo, Dae Won;Uhm, Dong Ok;Nam, Do-Hyun;Lee, Jung-Il;Kim, Jong Soo;Hong, Seung Chyul;Shin, Hyung Jin;Eoh, Whan;Kim, Jong Hyun
    • Journal of Korean Neurosurgical Society
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    • v.29 no.6
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    • pp.778-785
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    • 2000
  • Objectives : Intraoperative neurophysiologic monitoring(INM) is a well known useful method to reduce intraoperative neurological complications during neurosurgical procedures. Furthermore, INM is required in most cerebellopontine angle(CPA) surgery because cranial nerves or brain stem injuries can result in serious complications. Object of this study is to the correlation between the changes of intraoperative monitoring modalities during cerebellopontine angle tumor surgery and post-operative functional outcomes in auditory and facial functions. Material and Methods : Fifty-seven patients who underwent intraoperative neurophysiologic monitoring during CPA tumor surgery were retrospectively reviewed. Their lesions were as follows ; vestibular schwannomas in 42, other cranial nerve schwannomas in seven, meningiomas in five and cysts in three cases. Pre- and postoperative audiologic examinations and facial nerve function tests were performed in all patients. Intraoperative neurophysiologic monitoring modalities includes brainstem auditory evoked potentials(BAEP) and facial electromyographies(EMG). We compared the events of INM during CPA tumor surgeries with the outcomes of auditory and facial nerve functions. Results : The subjects who had abnormal changes during CPA tumor surgery were twenty cases with BAEP changes and facial EMG changes in twenty one cases. The changes of intraoperative neurophysiologic monitoring did not always result in poor functional outcomes. However, most predictable intraoperative monitoring changes were wave III-V complex losses in BAEP and continuous neurotonic activities in facial EMG. Conclusion : These results indicate that intraoperative neurophysiologic monitoring in CPA tumor surgery usually provide predictive value for postoperative functional outcomes.

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The Effects of Interrelationship after Wearing between Respirators and Glasses Simultaneously (안면부 여과식 방진 마스크와 안경 동시 착용 시 상호 영향)

  • Eoh, Won Souk;Shin, Chang Sub
    • Journal of the Korean Society of Safety
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    • v.33 no.1
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    • pp.47-53
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    • 2018
  • This study compares the interrelation of fit factor(FF) and visual acuity test by the order of wearing preference between Particulate filtering face piece respirators(PFFR) and glasses for 54 participants. Glasses fitting factors is Optical Center Height(OH), Vertex Distance(VD) and Pantoscopic Angle(PA) or Visual acuity. We measured those factors and expressed by the ratio of standard point and change point. Quantitative fit factor was measured by Portacount Pro+ 8038 and compared the result of preference of wearing order between respirators and glasses. Also, we selected to 6 exercises among 8 exercises OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The pass/ fail criterion of FF was set at 100. Visual acuity test chart is developed by Chunsuk Han was used, Descriptive statistics was performed. Descriptive statistics(SAS ver 9.2), it is used geometric means, Wilcoxon analysis, peason correlation(P=0.05) Fit factor was increased when the respirator was worn before wearing the glasses(p=0.000) and decreased for visual acuity(p=0.000) The negative correlation was showed between OH and Overall fit factor(r=-0.409, p=0.002). Among 54 participants, 11 participants(20.3%) were worn respirator before wearing glasses and 1 participant(1.9%) was worn glasses before wearing respirator. The overall fit test showed the higher level was investigated for the group of participants wearing respirator before wearing glasses in 6 exercises. Also, overall fit factor were increased when participants wore glasses prior to respirator(16.6) to respirator prior to glasses(36.6). Visual acuity were increased when participants wore respirator prior to glasses(93.8) to glasses prior to respirator(106.0). Finally, comparison result of overall fit factor and visual acuity were glasses first choice from mask first choice. The results showed that higher overall fit factor was investigate when the participants wore the respirator prior to glassess at all. The results implied that it is important to maintain the overall fit factor and visual acuity according to the consideration of OH for glasses fitting when worker wore respirator and glasses at the same time.

Mutational Analyses of Translation Initiation Factor eIF1A in Saccharomyces cerevisiae (Saccharomyces cerevisiae에서 번역 개시 인자 eIF1A 돌연변이에 대한 분석)

  • Kwon, Sung-Hun;Kim, Jun-Ho;Choi, Bo-Kyung;Kim, Na-Yeon;Choi, Do-Hee;Park, Kyoung-Jun;Eoh, Jung-Hyun;Bae, Sung-Ho
    • Korean Journal of Microbiology
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    • v.45 no.3
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    • pp.239-245
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    • 2009
  • Translation initiation factor eIF1A performs essential functions in various initiation steps including 43S preinitiation complex formation in eukaryotes, and contains a highly conserved oligonucleotide-binding (OB) fold. In our previous study, we discovered that eIF1A possesses RNA annealing activity and forms a stable complex with double-stranded RNA. In this study, we initiated site-directed mutations in eIF1A to find the active sites for these biochemical activities and to investigate whether they are essential functions for yeast cell growth. A truncated protein, eIF1A($\Delta$T), devoid of both N- and C-terminal domains but containing an intact OB-fold exhibited RNA annealing activity. In contrast, all point mutations in OB-fold domain, except R57D, impaired both RNA annealing and dsRNA binding activities, indicating that the intact OB-fold domain is required for both activities. Viabilities of the mutant yeast cells were not correlated with RNA annealing activity but with the in vivo protein stabilities in the case of R57D and K94D.

Effect of 8 Weeks Complex Exercise Program on The Height, Body Composition, Physical Fitness in Elementary School Children (8주간의 복합운동프로그램이 초등학생의 신장, 체성분, 체력에 미치는 효과)

  • Kwon, Se-Jin;Kim, Seul-Hee;Kim, Won-Ju;Eoh, Ji-Ye;Lee, Mi-Ae;Yu, Byong-Kyu
    • The Journal of Korean Academy of Sensory Integration
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    • v.11 no.1
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    • pp.29-37
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    • 2013
  • Objective : The purpose of this study was to investigate the effect of 8 weeks complex exercise program on height, body composition, and physical fitness in elementary school children. Method : The experimental group had 11 children (male=6, female=5) who belong to Seong-Nam Community Welfare Center in Gyeonggi-Do. All children received 50 minutes of complex exercise program 2 times a week for total of 8 weeks. In-body 520 were measured initially to serve as baseline data for height, and body composition. To determine the impact on physical fitness, Primus RS Power Track II commander Sit-up Trunk forward flexion measurement was also done. Repeat measurements of In-body520 Primus RS Power Track II Commander Sit-up Trunk forward flexion were done after 8 weeks. Results : There was significant increase in height, skeletal muscle mass, body fat percentage, lower limbs strength, and muscular endurance after the complex exercise program. There was, however, no significant difference in upper limbs strength, and flexibility after the program. Conclusions : These results indicate that the complex exercise program used in this study was very effective in producing significant benefits in height, body composition, and physical fitness in elementary school children. There would be better objective results if the control group and various environmental factors are considered in the future research.

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Design and Integrity Evaluation of High-temperature Piping Systems in the STELLA-2 Sodium Test Facility (STELLA-2 소듐 시험 시설 고온 배관 계통의 설계 및 건전성 평가)

  • Son, Seok-Kwon;Lee, Hyeong-Yeon;Ju, Yong-Sun;Eoh, JaeHyuk;Kim, Jong-Bum;Jeong, Ji-Young
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.9
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    • pp.775-782
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    • 2016
  • In this study, elevated temperature design and integrity evaluation have been conducted using two different piping design codes for the high-temperature piping systems of sodium integral effect test loop for safety simulation and assessment(STELLA-2) being developed by KAERI(Korea Atomic Energy Research Institute). The design code of ASME B31.1 for power piping and French nuclear grade piping design guideline, RCC-MRx RD-3600 were applied, and conservatism of those codes was quantified based on the piping integrity evaluation results. The piping system of Model DHRS, Model IHTS and PSLS are to be installed in STELLA-2. The integrity evaluation results for the three piping systems according to the two design codes showed that integrity of the piping system was confirmed. As a code comparison result, ASME B31.1 was shown to be more conservative for sustained loads while RD-3600 was more conservative for thermal loads compared to B31.1.

Aspergillosis of Central Nervous System (중추신경계의 Aspergillosis)

  • You, Seung-Hoon;Lee, Jung-Il;Nam, Do-Hyun;Kim, Jong-Soo;Hong, Seung-Chyul;Shin, Hyung-Jin;Park, Kwan;Eoh, Whan;Kim, Jong-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.30 no.7
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    • pp.896-902
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    • 2001
  • Objectives : Aspergillosis of central nervous system(CNS) is a rare pathologic condition and it has been known to be difficult to diagnose and treat. We analyzed seven cases of central nervous system aspergillosis. The clinical characteristics, and the problems in diagnosis and treatment are discussed with review of previous literatures. Material and Methods : We reviewed the clinical records, radiological findings, and pathologic reports of 7 patients with aspergillosis which involved CNS. Results : Five patients were immunocompetent, and infection was related with previous operation in 4 of them. Two patients were immunocompromised and had no history of operation. Five patients had intracranial lesions and two had spinal lesions. Mean duration from the onset of initial symptom to pathologic diagnosis was 2.4 months. Mean duration from the previous operation to the onset of symptom was 9.3 months, and from the onset of symptom to diagnosis was 2.9 months in the patients who had histories of operation. All of them were treated with surgical procedures and intravenous and oral antifungal agents, resulting in cure in 6 cases. Mean duration of the treatment was 4.9 months. Conclusion : Because aspergillosis of CNS is a rare disease and is difficult to be differentiated from the pyogenic abscess or recurrent tumor, the pathologic diagnosis is very important for adequate treatment. Although the prognosis of aspergillosis of CNS has been known to be poor, adequate surgery for both diagnosis and treatment and antifungal chemotherapy resulted in good outcome.

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Microsurgical Anatomy in Transoral Odontoidectomy (경구강 치상돌기제거술의 수술해부학)

  • Park, Kwan;Lee, Sang Koo;Cho, Tae Goo;Nam, Do-Hyun;Lee, Jung-Il;Kim, Jong-Soo;Hong, Seung-Chyul;Shin, Hyung-Jin;Eoh, Whan;Kim, Jong-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.29 no.3
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    • pp.309-316
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    • 2000
  • Objective :The transoral approach allows direct view of the ventral craniovertebral junction and provides useful management of the various lesions of this area. We present a step by step guide to the performance of the transoral excision of the odontoid process in the cadaveric model. Methods : Ten cadaver heads were used in fixed or unfixed state. We describe the relevant surgical anatomy in the cadaveric dissection and surgical technique of transoral transpharyngeal odontoidectomy. Results : The surgical procedure of transoral odontoidectomy was categorized by six steps;soft palate, posterior pharyngeal wall, muscular structures, osseous structures, odontoid process and ligaments, cruciate ligament and dura. Conclusion : With anatomical knowledge of these regions neurosurgeons can deal with wide variety of lesions in the ventral craniovertebral junction.

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Comparison of Recognition and Fit Factors according to Education Actual Condition and Employment Type of Small and Medium Enterprises (중소규모 사업장의 교육 환경과 고용형태에 따른 호흡보호구 인식도 및 밀착계수 비교)

  • Eoh, Won Souk;Choi, Youngbo;Shin, Chang Sub
    • Journal of the Korean Society of Safety
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    • v.33 no.6
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    • pp.28-36
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    • 2018
  • There was a difference in recognition of respirators according to the educational performance environment. they were showed higher recognition of respirators of group by internal and external mix trainer, less than 6 months, over 1hour, more than 5 times, variety of education. To identify the relationship between types of job classification(typical and atypical)and the levels of recognition of respirators, a total of 153 workers in a business workplace. mainly, typical workers showed higher recognition of respirators than atypical workers. Training of correct wearing showed high demands both typical and atypical workers. Descriptive statistics(SAS ver 9.2)was performed. the results of recognition of respirators were analyzed the mean and standard deviation by t-test, and anova, fit factor is used geometric means(geometric standard deviation), paired t-test, Wilcoxon analysis(P=0.05). Particulate filtering facepiece respirators (PFFR) is one of the most widely used items of personal protective equipments, and a tight fit of the respirators on the wearers is critical for the protection effectiveness. In order to effectively protect the workers through the respirators, it is important to find and evaluate the ways that can be readily applicable at the workplace to improve the fit of the respirators. This study was designed to evaluate effects of mask style (cup or foldable type) and donning training on fit factors (FF) of the respirators, since these are available at various workplace, especially at small business workplace. A total of 40 study subjects, comprised of employment type workers in metalworking industries, were enrolled in this study. The FF were quantitatively measured before and after training related to the proper donning and use of cup or foldable-type respirators. The pass/fail criterion of FF was set at 100. After the donning training for the cup-type mask, fit test were increased by 769%. but foldable-type mask was also increased after the donning training, the GM of FF for the foldable-type mask and it's increase rate were smaller as compared to the cup-type mask. Furthermore, the differences of the increase rates of the GM of FF in employment type of the subjects were not significantly for the foldable-type mask. These results imply that the raining on the donning and use of PFFR can enhance the protection effectiveness of cup or foldable-type mask, and that the training effects for the foldable-type mask is less significant than that for the cup-type mask. Therefore, it is recommended that the donning training and fit tests should be conducted before the use of the PFFR, and listening to workers opinion regularly.

Comparison of Participation and Satisfaction after a Change of a Teaching Method in Safety and Health Training Courses (안전보건교육과정별 참여도 및 교수방법 변경 후 만족도 비교)

  • Eoh, Won Souk;Lee, Sang Min;Cho, In Ok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.1
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    • pp.60-72
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    • 2021
  • Objectives: This study was performed to investigate the level of participation in and satisfaction with training courses at job training institutions and to improve participation and satisfaction through changes in the training method for industrial ventilation subjects. Methods: The results were analyzed for the mean and standard deviation by t-test and ANOVA, (p=0.05). Participation rates were examined for three courses: specialization, job training, and supervisory. The participation inthe education was 428 people, and the result of satisfaction with the change of education method was 878 people. Satisfaction was investigated for the specialized curriculum and job training curriculum,but not the supervisor curriculum. The satisfaction results for six items(contents, quality, skill, level, degree of understanding, degree of practical) were analyzed according to the change in the training medium and the method among people in one occupational ventilation subject. Results: The participation rate was similar in the job training and specialized training courses, but the lowest rate was in supervisory courses(p=0.05). In general, there was the lowest participation on the first day of education, and the participation rate improved after the second day. Satisfaction with the course was high for the specialized education course with a number of practical education assignments(p=0.278). The satisfaction level for the teaching method in the industrial ventilation subjects was high in a mixed group which combined lecture and practice. The industrial ventilation course in the basic job training course showed a difference between lecture and mixed education(p=0.111), but there was no significant difference. However, the industrial ventilation course in the advance job training course showed a clear difference between lecture and the mixed education(p=0.036). Conclusions: Therefore, the first day of training should start in the afternoon so that more trainees can participate, and it is recommended to assign important subjects after two days. In addition, it is suggested that job competency-enhancing education utilize various educational methods and media.

Effects of Personal Protective Equipment Practice Education on the Effectiveness of Repeated Learning and Satisfaction (개인보호구 실습교육의 반복학습 효과와 만족도에 미치는 영향)

  • Dae Jin Jo;Won Souk Eoh
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.33 no.2
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    • pp.156-170
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    • 2023
  • Objectives: This study conducted practical training to improve the proper usage of personal protective equipment(PPE), which greatly impacts workplace safety and health management. Personal protective equipment education was conducted through active participation, without theoretical modules, and aimed to identify the effects of repeated practical education and determine ways to increase participant satisfaction. Methods: Study data were analyzed using the IBM SPSS Statistics ver.29 software. First, participants' general characteristics were analyzed with frequency analysis. Second, the normality and equality of variances (Leven's test) were tested for the dependent variables prior to statistical analyses to determine the use of parametric tests. In general, normality is assumed when the sample size is 30 or more per the central limit theorem (Park et al., 2014). As our sample size of health management workers was 43, normality can be assumed. However, to ensure rigor of the study, we examined skewness and kurtosis. The results confirmed that the data were normally distributed. Third, the effects of repeated PPE training were analyzed using paired t-tests. Fourth, differences in satisfaction with PPE training according to the safety and health job position and safety and health certification were analyzed with t-test and Welch's t-test. For parameters that did not meet the assumption of equal variances, the Welch's t-test was performed. Results: Repeated PPE training improved the educational outcomes, and the improvements were significant in the 1st and 2nd respiratory PPE and safety and hygiene PPE training evaluations (p<.001). In terms of safety and health job position, repeated training led to improvements in educational outcomes, with significant improvements observed among supervisors and specialized health management institution workers in the 1st and 2nd training evaluations (p<.005). In terms of safety certification, repeated training led to improvements in educational outcomes, with significant improvements observed among both certified and non-certified individuals (p<.005). Regarding satisfaction with PPE training according to safety and health job positions, specialized health management institution workers showed greater satisfaction than supervisors, with significant differences in the satisfaction for expertise of lecture, work relevance, and lecturer's attitude (p<.001). Regarding satisfaction with PPE training according to safety and health certification, satisfaction was higher among certified individuals, with significant differences in satisfaction for work relevance and lecture attitude (p<.05) Conclusions: PPE education should be recommended to be provided as practical training. Repeated training can enhance educational outcomes for individuals with inadequate knowledge and understanding of PPE prior to education. For individuals with high levels of pre-existing knowledge and understanding of PPE, the results show that various training experiences should be provided to enhance their satisfaction. Therefore, it suggests that the workplace should actively seek educational media and methods to acquire expertise and skills in wearing personal protective equipment and improve the ability to use