• Korean Journal of Geomatics
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• v.3 no.1
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• pp.59-65
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• 2003

The merging of different scales or multi-sensor image data is becoming a widely used procedure of the complementary nature of various data sets. Ideally, the merging method should not distort the characteristics of the high-spatial and high-spectral resolution data used. To present an effective merging method for survey of reclaimed land using the high-resolution (6.6 m) Electro-Optical Camera (EOC) panchromatic image of the first Korea Multi-Purpose Satellite 1 (KOMPSA T-l) and the multispectral Moderate Resolution Imaging Spectroradiometer (MODIS) image data, this paper compares the results of Intensity Hue Saturation (IHS) and Principal Component Analysis (PCA) methods. The comparison is made by statistical and visual evaluation of three-color combination images of IHS and PCA results based on spatial and spectral characteristics. The use of MODIS bands 1, 2, and 3 with a contrast stretched EOC panchromatic image as a substitute for intensity was found to be particularly effective in this study.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9479-9485
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• 2014

Background: Cancer initiation and progression are controlled by genetic and epigenetic events. One epigenetic process which is widely known is DNA methylation, a cause of gene silencing. If a gene is silenced the protein which it encodes will not expressed. Objectives: 1. Identify the methylation status of BRCA1 in patients with epithelial ovarian cancer (EOC)and assess BRCA1 protein expression in tumor tissue. 2. Examine whether BRCA1 gene methylation and BRCA1 protein are associated with survival of epithelial ovarian cancer patients. Methods: The study design was a prospective-cohort study, conducted at Sardjito hospital, Yogyakarta, Indonesia. Results: A total of 69 cases were analyzed in this study. The data showed that the methylation status of BRCA1 in EOC was positive in 89.9%, with clear protein expression of BRCA1 in 31.9%. Methylation status and expression of BRCA1 were not prognosticators of EOC patients. Menarche, CA125 level, clinical stage and residual tumor were independent factors for prognosis.

• BMB Reports
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• v.42 no.6
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• pp.380-386
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• 2009

In neurodegenerative diseases, such as Alzheimer' and Parkinson', microglial cell activation is thought to contribute to CNS injury by producing neurotoxic compounds. Prothrombin and kringle-2 increase levels of NO and the mRNA expression of iNOS, IL-1$\beta$, and TNF-$\alpha$ in microglial cells. In contrast, the human prothrombin kringle-2 derived peptide NSA9 inhibits NO release and the production of pro-inflammatory cytokines such as IL-1$\beta$, TNF-$\alpha$, and IL-6 in LPS-activated EOC2 microglia. In this study, we investigated the anti-inflammatory effects of NSA9 in human prothrombin- and kringle-2-stimulated EOC2 microglia. Treatment with 20-100 ${\mu}M$ of NSA9 attenuated both prothrombin- and kringle-2-induced microglial activation. NO production induced by MAPKs and NF-$\kappa$B was similarly reduced by inhibitors of ERK (PD98059), p38 (SB203580), NF-$\kappa$B (N-acetylcysteine), and NSA9. These results suggest that NSA9 acts independently as an inhibitor of microglial activation and that its effects in EOC2 microglia are not influenced by the presence of kringle-2.

• Journal of Astronomy and Space Sciences
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• v.28 no.3
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• pp.225-232
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• 2011

We have designed and manufactured the Earth observation camera (EOC) of multi-purpose infrared imaging system (MIRIS). MIRIS is a main payload of the STSAT-3, which will be launched in late 2012. The main objective of the EOC is to test the operation of Korean IR technology in space, so we have designed the optical and mechanical system of the EOC to fit the IR detector system. We have assembled the flight model (FM) of EOC and performed environment tests successfully. The EOC is now ready to be integrated into the satellite system waiting for operation in space, as planned.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.101-105
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• 2014

Background and Purpose: Human epididymis protein 4 (HE4) has been suggested to be a novel biomarker of epithelial ovarian cancer (EOC). The present study aimed to evaluate and compare HE4 with the commonly used marker, carbohydrate antigen 125 (CA125), in prediction and therapy-monitoring of EOC. Patients and Methods: Serum HE4 concentrations from 123 ovarian cancer patients and 174 controls were measured by Roche electrochemiluminescent immunoassay (ECLIA). Risk of ovarian malignancy algorithm (ROMA) values were calculated and assessed. In addition, the prospects of HE4 detection for therapy-monitoring were evaluated in EOC patients. Results: The ROMA score could classify patients into high- and low-risk groups with malignancy. Indeed, lower serum HE4 was significantly associated with successful surgical therapy. Specifically, 38 patients with EOC exhibited a greater decline of HE4 compared with CA125. In contrast, elevation of HE4 better predicted recurrence (of 46, 11 patients developed recurrence, and with it increased HE4 serum concentrations) and a poor prognosis than CA125. Conclusions: This study suggests that serum HE4 levels are closely associated with outcome of surgical therapy and disease prognosis in Chinese EOC patients.

• BMB Reports
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• v.47 no.1
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• pp.33-38
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• 2014

The chemokine receptor 4 (CXCR4) plays an important role in the growth, angiogenesis and metastasis of various cancers, including epithelial ovarian cancer (EOC). However, the correlation between CXCR4 and the clinical response of EOC patients to chemotherapy remains unknown. 124 EOC patients were recruited to assess the relationship between CXCR4 and the response to cisplatin-based chemotherapy. The results showed that patients with a higher CXCR4 expression had a significantly lower chemosensitivity, a poorer progression-free survival and a lower overall survival than those with lower CXCR4 expression. In addition, knockdown of CXCR4 by small interfering RNA suppressed cell proliferation and resulted in G1/S arrest, increased apoptosis and chemosensitivity in both cisplatin-sensitive A2780 cells and cisplatin-resistant cell A2780/cis in vitro. Our data suggest that CXCR4 is one of the key molecules in cisplatin-based chemotherapy for EOC patients and that CXCR4 inhibition is a potential strategy to address the chemoresistance of EOC.

• Spatial Information Research
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• v.10 no.2
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• pp.331-343
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• 2002

Recently, as various fields of applications using space-borne imagery have been emphasized, interests on integrated analysis or fusion using multi-sources are also increasing. In this study, to investigate applicability of multiple imageries for further regional-scaled application, DN value analysis and multi-resolution classification by using KOMPSAT EOC imagery and Landsat 7 ETM+image data in the Namyangju-city area were performed, and then this classified results were compared to land-use thematic data at the same area. In case of classified results by using muff-resolution image data, it is shown that linear-type features can be easily extracted. furthermore, it is expected that multi-resolution classified image can be effectively utilized to urban environment analysis, according to results of similar pattern by comparative study based on multi-buffered zone analysis or so-called distance analysis along main road features in the study area.

• Elastomers and Composites
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• v.46 no.3
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• pp.251-256
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• 2011

Effect of poly(propylene-co-octene) as a compatibilizer in toughened polypropylene/ poly(ethylene-co-octene) (EOC) was investigated. The EOCs used were metallocene catalyzed commercial linear low density polyethylene and they are elastomeric materials. The poly(propylene-co-octene) was synthesized by metallocene catalyst in our laboratory to be used as a compatibilizer in PP/EOC blends. PP/EOC blends without compatibilizer shows very low mechanical properties in specimens with weldlines while incorporation of a compatibilizer significantly increases the mechanical properties of specimens with weldlines. However, compatibilized PP/EOC blends does not show increased impact property in a weldline free specimen and it is attributed to low molecular weight of the poly(propylene-co-octene) synthesized in present study. It is expected that the poly(propylene-co-octene) having increased molecular weight provides very good performance as an effective compatibilizer in toughened polypropylene/EOC blends.

• Korean Journal of Ecology and Environment
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• v.34 no.1 s.93
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• pp.20-29
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• 2001

The amount, chemical composition and optical property of extracellular dissolved organic carbon (EOC) by phytoplankton were examined using axenic cultures of Microcystis aeruginosa, Anabaena flos-aquae, and Oscillatoria agardhii. The extracellular organic matter was categorized into five fractions (hydrophobic acids; AHSs, hydrophobic neutrals; HoNs, hydrophilic acids; HiAs, hydrophilic bases; HiBs, and hydrophilic neutrals; HiNs) using three adsorbent resins(XAD-8, cation, and anion). The release pattern and chemical composition of EOC varied with algal species and their growth phases. Percentage of extracellular release increased with age in all cultures. HiAs were the dominant component of EOC in all cultures, whereas the proportion of HiAs decreased with age in all cultures. In contrast, the proportions of HiBs and HiNs increased as cultures aged. In particular, the HiN fraction increased from 0% to 44% of EOC in M. aeruginosa and from 3.0% to 28% in A. flos-aquae, respectively. The proportion of AHSs was higher in the cultures of A. flos-aquae(7.5${\sim}$16%) and O. agardhii (8.7${\sim}$16%) than M. aeruginosa(0.2${\sim}$2.5%). The proportions of AHSs increased with culture age in M. aeruginosa and O. agardhii, but decreased in A. flos-aquae. The specific UV absorbance also varied among species; 1.9 Abs${\cdot}$cm$^{-1}$/mgC${\cdot}$L$^{-1}$ for M. aeruginosa, 3.7 Abs${\cdot}$cm$^{-1}$/mgC${\cdot}$L$^{-1}$ for A. flos-aquae, and 13.0 Abs${\cdot}$cm$^{-1}$/mgC${\cdot}$L^{-1}$ for O. agardhii. The results of this study indicates that DOC excreted by three blue-green algae differed with species and the growth phase.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2004.04a
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• pp.251-257
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• 2004

The Electro-Optical Camera(EOC) image of the first Korea Multi-Purpose Satellitel(KOMPSAT-1) has both high resolution and convenient acquisition of research data, but on the other hand it has a defect of one band image. Fortunately, the multispectral Moderate Resolution Imaging Spectroradiometer (MODIS) image data are receiving every day at the Korea Aerospace Research Institute (KARI). Therefore, this paper performed an effective merging for survey of reclaimed land using the high-resolution (6.6m) KOMPSAT-1 EOC image and the multispectral MODIS image data. According this paper prepared map of reclaimed lands in Western Coast of North Korea as quantitative(position and form) survey of reclaimed lands of North Korea using merged image. The use of KOPSAT-1 EOC image and MODIS images was found to be economical such using of large scale areas as reclaimed land or according easy to collect information and such north korea as inaccessible areas like as receiving every day.