• Title/Summary/Keyword: EOC

Search Result 197, Processing Time 0.026 seconds

Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer

  • Innao, Pedrada;Pothisuwan, Methasinee;Pengsa, Prasit
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.9
    • /
    • pp.4483-4486
    • /
    • 2016
  • Background: Despite the fact that ovarian cancer is the seventh most common cancer in women worldwide and the fifth leading cause of cancer death, It is the most common cause of death due to reproductive cancers in Thailand where epithelial ovarian cancer (EOC) is commonly found. According to a Thai statistical analysis in 2010 by the Department of Medical Services, epithelial ovarian cancer was the sixth most common cancer in Thailand from 2001to 2003.The incidence of 5.1 per 100,000 women per year. Human epididymis protein 4 (HE4) is a novo diagnostic tumor marker for EOC. The combination of HE4 and carcinoma antigen 125 (CA 125) is a tool for detecting epithelial ovarian cancer (EOC) better than using CA 125 alone. Therefore, the researcher is interested in HE4 does have a role to predict recurrent epithelial ovarian cancer. Materials and Methods: The patients who had complete response after diagnosed with epithelial ovarian cancer by pathology, FIGO stage 3 or more had been treated through surgery and chemotherapy at the Sunpasitthiprasong Hospital from June 2014 until March 2016. The patients were followed up every three months, using tumor marker (CA 125, HE4,Carcinoma antigen 19-9) together with other checkup methods, such as rectovaginal examination, CXR every year and other imaging as indication. Afterwards, the data was analyzed for the ability of HE4 to detect recurrence of epithelial ovarian cancer. Results: In 47 patients in this study follow-up for 22 months after complete response treatment from surgery and chemotherapy in epithelial ovarian cancer, 23 had recurrent disease and HE4 titer rising. The patients with recurrent epithelial ovarian cancer demonstrated high levels of both HE4 and CA125 with sensitivity of 91.3% and 52.7% respectively, specificity of 87.5% and 95.6% and positive predictive values of 87.5% and 85.7%. HE4 can predict recurrent epithelial ovarian cancer (p-value=0.02242). Comparing HE4 and CA125 in predicting recurrent epithelial ovarian cancer HE4 had more potential than CA125 (p-value =0.8314). Conclusions: The present study showed HE4 to have a role in predicting recurrent epithelial ovarian cancer and HE4 is potentially better than CA125 as a marker for this purpose.

An ELISA-on-a-Chip Biosensor System for Early Screening of Listeria monocytogenes in Contaminated Food Products

  • Seo, Sung-Min;Cho, Il-Hoon;Kim, Joo-Ho;Jeon, Jin-Woo;Oh, Eun-Gyoung;Yu, Hong-Sik;Shin, Soon-Bum;Lee, Hee-Jung;Paek, Se-Hwan
    • Bulletin of the Korean Chemical Society
    • /
    • v.30 no.12
    • /
    • pp.2993-2998
    • /
    • 2009
  • An enzyme-linked immunosorbent assay (ELISA)-on-a-chip (EOC) biosensor combined with cell concentration technology based on immuno-magnetic separation (IMS) was investigated for use as a potential tool for early screening of Listeria monocytogenes (L. monocytogenes) in food products. The target analyte is a well-known pathogenic foodborne microorganism and outbreaks of the food poisoning typically occur due to contamination of normal food products. Thus, the aim of this study was to develop a rapid and reliable sensor that could be utilized on a daily basis to test food products for the presence of this pathogenic microorganism. The sensor was optimized to provide a high detection capability (e.g., 5.9 ${\times}\;10^3$ cells/mL) and, to eventually minimize cultivation time. The cell density was condensed using IMS prior to analysis. Since the concentration rate of IMS was greater than 100-fold, this combination resulted in a detection limit of 54 cells/mL. The EOC-IMS coupled analytical system was then applied to a real sample test of fish intestines. The system was able to detect L. monocytogenes at a concentration of 2.4 CFU/g after pre-enrichment for 6 h from the onset of cell cultivation. This may allow us to monitor the target analyte at a concentration less than 1 CFU/g within a 9 h-cultivation provided a doubling time of 40 min is typically maintained. Based on this estimation, the EOC-IMS system can screen and detect the presence of this microorganism in food products almost within working hours.

A Study on the selection and noise test of elelctronic sensor for Vacuum Circuit Breaker (진공차단기용 전자식 센서의 선정 및 노이즈 시험에 관한 연구)

  • Lee, Ki Seon;Park, Jung Cheul;Chu, Soon Nam
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.18 no.10
    • /
    • pp.2503-2508
    • /
    • 2014
  • This study is about the selection and noise test of electronic sensor which is preceded by electric Operating Cell(EOC) development using electronic sensor technology to solve the structural weakness of Mechanism Operated Cell(MOC) in VCB, and has a final target in product development minimizing contact malfunction of the chattering or rebounce states caused by existing MOC. In this test results, when opening and closing VCB, rising velocity of surge voltage in opening time was measured 4.2 times faster than closing time and noise decibel value was measured respectively 120dB and 110dB. When supplying 60kV power frequency overvoltage, we found that sensor output graph in VCB opening and closing times operated stably without distortion. When supplying 150kV $1.2{\times}50{\mu}s$ impulse frequency voltage, we found that voltage graph of output contact in sensor opening and closing sides maintained a normal condition without distortion, and when supplying 2500A current, we found that tested result of electric field noise operated stably without distortion.

인공위성영상 전처리시스템의 RPC(Rational Polynomial Coefficients) 기하보정모듈 생성

  • Seo, Doo-Chun;Lee, Dong-Han
    • Aerospace Engineering and Technology
    • /
    • v.4 no.1
    • /
    • pp.229-238
    • /
    • 2005
  • The main objective of this study is to develop RPC geometric correction module for the pre-processing systems of the satellite image. For this purpose, the Terrain-Independent Ⅰ, Terrain-Independent Ⅱ and Terrain-Dependent Ⅲ have been applied in tests with KOMPSAT-1 EOC and SPOT PAN images.

  • PDF

Development of the Ku band Antenna Subsystem for the CBS Payload System (Ku 대역 통신방송위성(CBS) 탑재체 안테나 개발)

  • 윤소현;김영철;이점훈;박종흥;이성팔;우형제
    • Proceedings of the IEEK Conference
    • /
    • 2003.07a
    • /
    • pp.258-261
    • /
    • 2003
  • 한반도와 그 주변 지역에 멀티미디어 서비스를 제공하기 위해 통신방송위성(CBS: Communications and Broadcastings Satellite) 탑재체의 Ku 대역 안테나가 개발되었다. Ku 대역 안테나는 성능 요구 조건을 만족하도록 설계 되었으며 일련의 시험을 통해 성능 검증이 이루어졌다. 일련의 시험은 초기 성능 시험(IFPT: Initial Functional Performance Test), 환경 시험, 최종 성능 시험(FFPT: Final Functional Performance Test)으로 구성되며 이를 통해 반사 손실, EOC(Edge Of Coverage) 이득, 사이드로브 레벨, 교차 편파 분리도등의 전기적 성능과 발사 및 우주 환경에서 강건함이 확인되었다.

  • PDF

Three-Dimensional Modeling Using KOMPSAT-1 Strip Images (KOMPSAT-1 스트립영상의 3차원 모델링)

  • Yoo, Hwan-Hee;Kim, Uk-Nam;Kim, Dong-Kyoo;Jeong, Ju-Kwon
    • 한국지형공간정보학회:학술대회논문집
    • /
    • 2002.03a
    • /
    • pp.137-144
    • /
    • 2002
  • 본 연구에서는 KOMPSAT-1호 EOC 위성영상으로 구성한 스트립영상과 영상의 헤더 정보를 이용하여 3차원 위치결정 모델링을 수행하여 그 정확도를 평가하였다. 스트립영상은 동일한 패스를 촬영한 단영상들을 연속적으로 접합시켜 구성하였다. 이 방법은 접근가능지역에서 기준점으로 오차보정을 실시한 후 비접근지역으로 연결되는 스트립영상을 기준점 필요 없이 위치결정을 할 수 있는 방법으로 비접근지역에 대한 지형정보 취득에 효과적인 방법으로 판단하였다.

  • PDF

Study on Practical MTF Budget of Satellite Electro-Optical Imaging System (위성 전자광학 결상계의 실용적 MTF 성능 지표)

  • 조영민
    • Proceedings of the Optical Society of Korea Conference
    • /
    • 2001.02a
    • /
    • pp.80-81
    • /
    • 2001
  • 우주에서 작동이 검증되었고 영상 품질이 잘 알려진 기존 위성 전자광학 결상계들의 MTF 특성을 분석하여 위성 전자광학 결상계 설계에서 실제로 적용될 수 있는 최적화된 MTF 성능 지표를 구하는 방법을 제시하였다. KOMPSAT-1 EOC와 IKONOS에 대해 이론적 한계가 잘 알려진 MTF 성분들인 광학회절한계 MTF와 Spatial 및 Temporal Sampling MTF를 분석하여 실용적인 MTF 성능 지표를 구하였고, 이 지표를 이용하여 몇 가지 광학계의 최소 구경을 추정하여 지표의 실용성을 검토하였다. (중략)

  • PDF

기하보정 방법에 따른 광학영상자료의 지형효과 분석

  • 이성순;지광훈
    • Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
    • /
    • 2004.03a
    • /
    • pp.251-254
    • /
    • 2004
  • 최근 인공위성 영상자료의 해상도가 높아짐에 따라 영상을 통해 얻을 있는 정보의 양이 증가하고 있다. 영상의 식별력이 증가함으로써 영상에서 얻을 수 있는 정보량이 증가하지만 그와 함께 정보의 질이 향상되었다고 판단하기는 어렵기 때문에 지형과 영상의 정밀보정은 매우 중요하다 특히, 광학센서 기반의 인공위성 자료는 영상자료의 공간해상도 뿐만 아니라 촬영시기, 지형형태 둥 많은 내ㆍ외부 조건에 따른 특성을 가지고 있다. 이러한 특성은 표고가 높은 지형에서 더욱 크게 영향 받는다. 이에 본 연구에서는 Kompsat EOC 및 Spot-5 등 다양한 광학위성 센서에 대한 지형효과 특성을 위성의 기하정보 등록방법에 따라 분석함으로써 자료 이용의 효용성 제고에 기여하고자 한다.

  • PDF

Generation of High Resolution DEM of Jeju Island

  • Lee, Chang-Won;Kim, Duk-Jin;Moon, Wooil M.
    • Proceedings of the KSRS Conference
    • /
    • 2003.11a
    • /
    • pp.831-833
    • /
    • 2003
  • We have evaluated the accuracy of digital elevation models of Jeju island generated with three different sensors, NASA JPL TOPSAR, JERS-1 SAR, KOMPSAT-1 EOC using Interferometric SAR and stereo photogrammetry. Characteristics and limitations of each method are described.

  • PDF

Comparative Study of GDPA and Hough Transformation for Automatic Linear Feature Extraction

  • Ryu, Hee-Young;Lee, Ki-Won;Kwon, Byung-Doo
    • Proceedings of the KSRS Conference
    • /
    • 2003.11a
    • /
    • pp.238-240
    • /
    • 2003
  • As remote sensing is weighty in GIS updating, it is indispensable to get spatial information quickly and exactly. In this study, we have designed and implemented the program by two algorithms of GDPA (Gradient Direction Profile Analysis) and Hough transformation to extract linear features automatically from high-resolution imagery. We applied the software to embody both algorithms to KOMPSAT-EOC, IKONOS, and Landsat-ETM and made a comparative study of results.

  • PDF