• The Journal of the Korea Contents Association
• /
• v.17 no.7
• /
• pp.648-663
• /
• 2017

To verify the association between GSTM1/GSTT1 gene polymorphisms and susceptibility to autoimmune diseases in Asian population. 18 published reports cited in EMBASE, Google, KISS, MEDLINE and PubMed up to December 2015 were collected for a meta-analysis. The GSTM1/GSTT1 polymorphism for null and present type were analysed separately. The significant association was found between the GST polymorphism and autoimmune diseases in an overall population (GSTM1, OR=1.334, 95% CI=1.137-1.567, p=0.000; GSTT1, OR=1.212, 95% CI=1.012-1.452, p=0.037). Asian population showed the significant association of GSTM1 in the autoimmune diseases, especially vitiligo and atopic dermatitis but non-significant association of GSTT1 in RA and SLE. The GSTM1 null and the GSTT1 present type showed the association with autoimmune diseases in Asian population. The null type frequency of the combination of GSTM1-GSTT1 polymorphism in autoimmune diseases in Asian population was higher than that of the control group. This result indicated that null type of GSTM1-GSTT1 combination can be a risk factor of autoimmune diseases in Asian population.

• The Journal of the Korea Contents Association
• /
• v.14 no.6
• /
• pp.219-228
• /
• 2014

The purpose of this study was to determine the trends of research on the effects of psychosocial intervention related to children with epilepsy. 454 articles were retrieved from databases (Ovid-MEDLINE, EMBASE, PubMed, CINAHL, The Cochrane library, KMbase, and Koreamed), and 7 articles met our criterias. Interventions were classified into four categories: education; counseling; cognitive-behavioral therapy; and physical activity. The target outcomes of the interventions were quite diverse. Each intervention showed some benefits for epilepsy-related health outcomes, but each study had methodological weaknesses, including incomplete information, poorly defined or validated outcome measures, small sample sizes, and design limitations.

• Journal of the Korea Convergence Society
• /
• v.12 no.9
• /
• pp.373-385
• /
• 2021

The purpose of this paper is to systematically evaluate the relationship between cancer health literacy and cancer screening behaviors using global data. Following the preferred reporting items for systematic reviews and meta-analyses review guidelines, full-text articles published on PubMed, CINAHL, Embase, and Cochrane Library were reviewed until 31 January 2021. The reference lists of all selected studies have been also included. The cancer health literacy and cancer-screening behaviors of the participants aged ≥18 years were assessed. Seventeen studies that met the inclusion criteria were included. The cancer screening behaviors included mammograms, clinical breast cancer examination, Papanicolaou test, colonoscopy, and PSA screening. Eleven studies revealed a statistically meaningful relationship between the cancer health literacy and cancer screening behaviors. Further research should focus on developing effective interventions and guidelines on cancer health knowledge. The research scope of all areas of cancer health literacy and cancer screening behaviors should be extended to improve the cancer screening rates and public health.

• Therapeutic Science for Rehabilitation
• /
• v.10 no.2
• /
• pp.53-74
• /
• 2021

Objective : The purpose of this study was to examine foreign literature on the evaluation and interventions for motor functions in children. Methods : Studies in this review were identified by searching the PubMed, Cochrane Library (Embase) databases from those published form January 2010 to March 2020 using the following keywords: "motor function test" or "motor function measure" or "movement assessment" or "motor proficiency test" or "motor scale" or "motor skill" and children. Results : Of the total 37 identified studies, 14 analyzed evaluations, 23 analyzed interventions, all of which were randomized control trials. Studies on evaluations were increasingly more common, in contrast to studies on interventions for motor functions. The most frequent field of research was rehabilitation. The studies on evaluations included the AIMS and MABC-II, and GMFM was the most frequently used intervention. Interventions were most commonly used in task-oriented training (six studies). Conclusion : This study aimed to provide a basis for therapists to choose effective motor function evaluation and interventions for clinical trials by analyzing studies related to interventions for and evaluation of motor function in children.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.32 no.3
• /
• pp.102-115
• /
• 2019

Objectives: The purpose of this study is to confirm the effectiveness and safety of acupuncture for treating breast cancer-related lymphedema (BCRL), thus providing a clinical basis for acupuncture treatment and helping to develop clinical practice guideline through consideration of used meridians and acupoints. Methods: Clinical studies applying acupuncture on breast cancer-related lymphedema were searched through 7 databases such as The Cochrane Library Central, Embase, Pubmed and CAJ. Interventions and results of the selected clinical studies were analyzed. Results: 8 Clinical studies were finally included according to inclusion and exclusion criteria. There were 6 randomized controlled studies and 2 single-arm pilot studies. All of those studies were searched in The Cochrane Library Central, Embase, Pubmed and CAJ and written in English and Chinese. Treatment group applied acupuncture as a Korean medicine intervention. Interventions of control group were made with non-treatment, upper limb exercise, and oral administration of capillary stabilizer or diuretics. Outcome measurements varied from paper to paper but every study measured reduction in arm circumference. Among 8 studies, 6 studies reported statistically significant reduction in arm circumference in treatment group and there were no serious adverse effects. Conclusions: This study suggested that acupuncture has few side effects as well as statistically significant effects on many aspects in treating breast cancer-related lymphedema. However the results should be taken cautiously as more clinical studies are needed.

• The Journal of Korean Academy of Sensory Integration
• /
• v.18 no.3
• /
• pp.39-52
• /
• 2020

Objective : The purpose of this study was to investigate the effect of parent education on feeding problems in children with autism spectrum disorder. Method : Articles published between 2000 and May 2019 were identified through a database search of Cochrane Library, Embase, Ovid-Medline, and PubMed as well as through additional manual searches. A total of six articles were selected and qualitatively analyzed according to the level of evidence of the study and arranged according to PICO (Patient, Intervention, Comparison, Outcome). Results : Six articles were used for the data analysis; four articles were at evidence level 1 and two articles were at evidence level 3. Behavioral therapy was the most common interventional approach to parent education, and all of the articles based on behavioral therapy had evidence level 1. Conclusion : This study examines the various ways of parenting to help families with autism spectrum children with feeding problems in order to find directions for parent education that can be applied in clinical practice.

• Journal of Digital Convergence
• /
• v.19 no.3
• /
• pp.195-202
• /
• 2021

This study is a systematic review study to confirm the characteristics, effects, and application strategies of domestic and foreign virtual reality programs provided by dementia education. This study is based on the literature published up to July 2020, CINAHL, Cochrane, EMBASE, and Pubmed electronic databases were used overseas, and RISS, KISS, and DBpia were searched in Korea. Based on the selection criteria and exclusion criteria, the final six papers were used for analysis. As a result of the analysis, the subjects of the selected literature were two informal caregivers (33.3%), one general (16.7%), and three students (50.0%) including nursing students and medical and pharmacy students. The virtual reality program was effective in a total of five areas(empathy ability, dementia attitude including knowledge and comfort of dementia, trust in own abilities, dyadic relationship scale), of which 75% of the studies measured empathy ability had significant effects. The results of this study confirm that virtual reality technology can be used for human-centered nursing based on empathy.

• Biomedical Science Letters
• /
• v.27 no.4
• /
• pp.298-309
• /
• 2021

Rheumatoid arthritis refers to acute and chronic arthritis due to unexplained autoantibody attack. Rheumatoid arthritis should be accompanied by difficulty in mobility and severe distress due to the progression of systemic arthritis. Therefore, this study early diagnoses the effects of Rheumatoid factor (RF), C-reactive protein (CRP), and Anti-cyclic citrullinated peptide (Anti-CCP), which are typical serum markers for rheumatoid arthritis by meta-analysis. Pubmed and EMBASE, were used as PICO criteria, and two independent researchers selected papers according to the criteria set in this study. The selection criteria was a study of patients with rheumatoid arthritis who developed early onset, and the paper was evaluated using the NCS. Forest plot and Funnel plot graphs for each serum marker were calculated using Revman 5.4. After finding 193 papers on Pubmed and 184 papers on EMBASE and selecting according to the criteria, a total of 41 papers were used for the analysis. The magnitude of the effect that appears in the Forest plot of RF with the Mean differnce value is 134.34, CRP is 21.42 and Anti-CCP is 270.41. The magnitude of the effect of Anti-CCP in meta-analysis was analyzed to be larger than that of RF and CRP, and it is considered that the development of early-diagnosis serum markers using Anti-CCP and additional retrospective studies are highly effective. The combination of RF, CRP, and Anti-CCP as a panel marker is expected to be very efficient.

• The Journal of the Korea Contents Association
• /
• v.22 no.10
• /
• pp.475-487
• /
• 2022

The purpose of this study is to comprehensively examine the facilitators and barriers to social participation of older adults in the society through systematic review of qualitative research. Through PubMed, Embase, Cochrane, data from 2012 to 2022 were collected. The main search keywords were 'elderly', 'older adults', social participation', 'engagement', 'motiv^*', 'barrier', 'facilitat^*'. 7 articles that satisfy the inclusion criteria were selected for analysis. Facilitators and barriers of older adults' social participation were analyzed. The analyzed factors were assorted into 'personal/ internal factors', 'environmental factors', 'social network factors'. The results of this study emphasize not only logistical factors, but also motivation, desire, social context of older adults' as factors to social participation. To prevent older adults' social isolation, a broad understanding of what promotes and inhibits the participation of the older adults is needed.

• Journal of Industrial Convergence
• /
• v.20 no.9
• /
• pp.71-79
• /
• 2022

This study comprised a systematic review and meta-analysis to determine how digital health care to relieve depression of the elderly. The CINAHL, Embase, Medline, DBpia, KERIS, KISS and RISS were used. As a result of the systematic search, a total of 4,071 studies were assessed and six studies were ultimately selected based on the inclusion and exclusion criteria. Of these, a total of five studies were available for meta-analysis; the effect size was calculated. The effect size of digital health care was statistically significant in reducing depression(SMD=-4.73, 95% CI -7.44 to -2.01, Z=3.41, p=.0007). Since only web-based programs are included in the analysis among types of digital health care, we suggest that we consider ways to reduce depression in the elderly by applying various digital health care in the future.