• Natural Product Sciences
• /
• v.21 no.1
• /
• pp.25-29
• /
• 2015

In a continuation of our studies to discover bioactive secondary metabolites from marine sources, we further investigated samples from a tryptamine and phenyl-alkane producing sponge, which resulted in the isolation of four uncommon small molecules and five nucleosides. Their structures were determined to be 7,8-dihydroimidazo[1,5-c]pyrimidin-5(6H)-one (1), 5-chlorocavernicolin (2), maleimide-5-oxime (3), 3-methylmaleimide-5-oxime (4), uridine (5), 2'-deoxyuridine (6), thymidine (7), adenine (8), and adenosine (9) by spectroscopic analyses. The isolated compounds were evaluated for inhibitory activity against soluble epoxide hydrolase (sEH) as well as the Wnt/${\beta}$-catenine signaling pathway.

• Proceedings of the Korean Society for Applied Microbiology Conference
• /
• 1986.12a
• /
• pp.514.3-515
• /
• 1986

λP$_{L}$ promoter와 Infiuenza virus의 NS1 Structural gene이 있는 pASl EH801 plasmid를 E. coli host N5' 과 AR120에 각각 transformation하여 온도와 nalidixic acid로 각각 induction 하여 보았다 N5151의 경우, O.D.600 1.2에서 42$^{\circ}C$로 induction하였을 때 maximum productivity를 보였으며 AR120의 경우는 O. D. 600 1.2, 37$^{\circ}C$, 40$\mu\textrm{g}$ nalidixic acid/$m\ell$ induction 하였을 때 maximum yield를 보여주었다. 이때 pH, DO, temperature, $O_2$%, $CO_2$%를 A/D converter통해 computer에 연결시켜 data acquision을 한 결과, 접종 후 ON-line induction이 가능함을 알 수 있었다.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.28 no.6
• /
• pp.1239-1243
• /
• 1999

The optimal medium composition for the production of carotenoid pigment from Haloarcular sp. EH 1 as a dietary for fishes were 1.0% sucrose, 1.0% yeast extract, 25% sodium chloride, 0.3% sodium citrate, 0.2% potassium chloride, 2.0% magnesium sulphate, 0.002% ferric sulphate(pH 7.0). The incubation temperate, aeration rate and agitation speed were 40oC, 100ml medium/500ml vol. shaking flask, and 180 rpm/min. The carotenoid pigment production was highest after 5 days of incubation with the light.

• Journal of environmental and Sanitary engineering
• /
• v.15 no.4
• /
• pp.91-97
• /
• 2000

The objective of this study was to evaluate the possiblity of Foodwaste and co-treatment with other waste for vermistabilization. The value of oxidation-reduction potential(Eh) of the dewaterized foodwaste by a plant of subatmospheric evaporation was a possitive(+) value indicating, but the values of pH, salinity was idicating an unfavorable condition for earthworm life. The paper mill mixing waste properties by ripening for 20days were changed into the favorable range for earthworm. The growth of earthworms in foodwaste and mixing waste of paper mill 30% was found to be 68%, 84% for the survival rate, 227%, 275% for the liveweight increasing rate, respectively. The ingestion rate of foodwaste and mixing waste of paper mill 30% indicate 0.72g/g·d, 0.81g/g·d, respectively. About 62∼75% of ingestion amount produce cast and characteristics of cast indicate pH 6.1∼6.5 organic component 34∼42%, salinity 0.35∼0.4, CEC 73∼94 me/100g, N, P, K concentration 0.8∼1.2%, 0.4∼1.6%, 0.43∼0.5% respectively. Therefore it can be evaluated that the casts are good soil condition and organic fertilizer.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.7 no.3
• /
• pp.171-180
• /
• 2002

The temporal and spatial distributions of phosphorus have been investigated in the Gomso Bay, Korea. TP, PIP, TOP and DIP in sediment were found 548.8mg P kg$^{-1}$ , 426.1mg P kg$^{-1}$ , 122.6mg P kg$^{-1}$ , and 0.217mg P kg$^{-1}$ , respectively with a decreasing order of PIP>TOP>DIP. Any temporal or spatial trend has not been found on the distribution of TP in the sediment, except the high TP values near the mouth of Julpo-chun. We found seasonal patterns high TOP(28.90% of TP) and low TIP(71.10% of TP) in August, but low TOP(15.63% of TP) and high TIP(84.38% of TP) in November. There were three times higher DIP concentration in August than in November. Such case is probably not only due to the enhanced supply of DIP directly from the decomposition of organic matter from overlying water in summer, but also the released phosphate from the adsorbed particulate matter such as PIP under the low pH and Eh conditions at the subsurface layers of the sediment induced by the active microbial respiration of increased organic materials in summer. Primarily, the source of phosphorous from municipal sewage strongly influenced the early stage of the distribution of all the phosphorous in the Gomso tidal flat. Notwithstanding, through the processes of diagenesis in sediment, water temperature and organic contents probably functioned as the key parameters to control the temporal distributions of TOP, TIP and DIP in the Gomso tidal flat.

• Economic and Environmental Geology
• /
• v.41 no.1
• /
• pp.47-56
• /
• 2008

pH and Eh were measured at 25 points in the abandoned Dalcheon mine. And, major ion components $(Na^+,\;K^+,\;Ca^{2+},\;Mg^{2+},\;Cl^-,\;SO_4^{2-},\;CO_3^{2-},\;HCO_3^-)$ were analyzed through groundwater sampling at 41 points. pH and Eh were measured the highest concentration in serpentinite area. And, pH was between weak alkaline and intermediate values in study area. Groundwater in study area was dominated oxidation-reduction environment caused by reaction with carbonate rock. Because sulfur components contained in carbonate, serpentinite, arsenopyrite and pyrite was dissolved by groundwater, $SO_4^{2-}$ component was high in study area. And $Ca^{2+},\;Mg^{2+}$ of cations were high. Correlation coefficients of ion components in tailing dumps were 0.95 between $Ca^{2+}\;and\;SO_4^{2-}$, 0.86 between $Ca^{2+}\;and\;Mg^{2+}$, 0.85 between $Mg^{2+}\;and\;SO_4^{2-}$. Correlation coefficients of ion components in bedrock were 0.86 between $Mg^{2+}\;and\;SO_4^{2-}$, 0.68 between $Ca^{2+}\;and\;SO_4^{2-}$. Concentration range of $Ca^{2+}$ in tailing dumps was $6.85{\sim}323.58mg/L,\;and\;3.18{\sim}207.20mg/L$ in bedrock. Concentration range of $SO_4^{2-}$ in tailing dumps was $21.54{\sim}1673.17mg/L,\;and\;2.04{\sim}1024.64mg/L$ in bedrock. By the result of Piper diagram analysis with aquifer material, groundwater in tailing dumps was $Ca-SO_4$ type. Groundwater quality types with bedrock material were Mg-$SO_4$ and Mg-$HCO_3$ types in serpentinite area, Ca-$HCO_3$ type in carbonate area, Na-K and $CO_3+HCO_3$ types in hornfels, respectively. As a result of this study, groundwater in tailing dumps were dissolved $Ca^{2+},\;Mg^{2+}\;and\;SO_4^{2-}$ components with high concentration. Also, these ion components were transported into bedrock aquifer.

• Korean Journal of Food Science and Technology
• /
• v.33 no.5
• /
• pp.619-625
• /
• 2001

We determined whether the supplementation of Polygonatum Odoratum (Mill) Druce (POD) extract had a good effect on insulin resistance in peripheral tissues of 90% pancreatectomized (Px) and sham-operated (Sham) male Sprague Dawley rats. Px and Sham rats were divided into two groups; one group daily consumed 0.3 g of POD extracts per 1 ㎏ body weight for two months, and the other group had a placebo. All rats freely consumed a 40% fat diet. At the end of the experiment, a euglycemic hyperinsulinemic (EH) clamp was performed in a fasting, awake, and unstressed state to determine insulin resistance. At EH clamp, body weights were higher in Sham rats than Px rats, and serum glucose levels of baseline were affected by diabetic status and POD administration. Serum insulin concentrations were higher in Sham rats than Px rats, and POD administration decreased them in Sham rats compared to P. Glucose disposal rates in peripheral tissues increased with POD in both Px (n=10) and Sham (n=10) rats. But glycogen deposits in soleus muscle increased with POD administration in Px and Sham rats, and total glycogen synthase activity and fraction velocity were higher in POD groups. Triglyceride contents in quadriceps muscles decreased with POD in Px rats. In conclusions, POD improves insulin resistance by enhancing glucose utilization with increasing glycogen deposit and decreasing triglyceride contents in muscles.

• The Journal of Fisheries Business Administration
• /
• v.47 no.4
• /
• pp.1-13
• /
• 2016

Fish mortality is the most important success factor in aquaculture management. To analyze the effect of mortality considering biological and economic condition is a important problem in land-based aquaculture. This study is aimed to analyze the effect of mortality for duration of cultivation in land-based aquaculture. This study builds the mathematical model that finds the value of decision variable to minimize cost that sums up the water pool usage cost, sorting cost, fingerling cost and feeding cost under critical standing corp constraint. The proposed mathematical model involves many aspects, both biological and economical: (1) number of fingerlings (2) timing and number of batch splitting event, based on (3) fish growth rate, (4) mortality, and (5) several farming expense. Numerical simulation model presented here in. The objective of numerical simulation is to provide for decision makers to analyse and comprehend the proposed model. When extensive biological and cost data become available, the proposed model can be widely applied to yield more accurate results.

• Asia pacific journal of information systems
• /
• v.12 no.1
• /
• pp.1-16
• /
• 2002

Most of searching systems used by shopping-mall provide too much information for user requirements or fail to provide appropriate items reflecting customer's preference. This paper aims to design and implement the product searching systems based on customer preference which will enable efficient product selection in the internet shopping-mall. The proposed system consists of user/provider interface, searching and model agent, data management system, and model management system. Especially, we construct the searching pattern database to support fast search using association mining method. And this system includes the customer-oriented decision model which shows the highly preferred products. Input weight value per attribute and preference level should be needed to compute priority grade of preference.

• The Journal of Fisheries Business Administration
• /
• v.46 no.3
• /
• pp.129-141
• /
• 2015

Because land based aquaculture is restricted by high investment per rearing volume and control cost, good management planning is important in Land-based aquaculture system case. In this paper master production planning was made to decide the number of rearing, production schedule and efficient allocation of water resources considering biological and economic condition. The purpose of this article is to build the mathematical decision making model that finds the value of decision variable to maximize profit under the constraints. Stocking and harvesting decisions that are made by master production planning are affected by the price system, feed cost, labour cost, power cost and investment cost. To solve the proposed mathematical model, heuristic search algorithm is proposed. The model Input variables are (1) the fish price (2) the fish growth rate (3) critical standing corp (4) labour cost (5) power cost (6) feed coefficient (7) fixed cost. The model outputs are (1) number of rearing fish (2) sales price (3) efficient allocation of water pool.