• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.2
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• pp.141-149
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• 2002

Although the finite element method has become an indispensible tool for the dynamic analysis of structures, difficulty remains to quantify the errors associated with discretization. To improve the modeling accuracy, this paper proposes a method to make a combined use of finite elements and exact dynamic elements. Exact interpolation functions for the Timoshenko beam element are derived using the exact dynamic element modeling (EDEM) and compared with interpolation functions of the finite element method (FEM). The exact interpolation functions are tested with the Laplace variable varied. A combined use of finite element method and exact interpolation functions is presented to gain more accurate mode shape functions. This paper also presents a combined use of finite elements and exact dynamic elements in design/reanalysis problems. Timoshenko flames with tapered sections are tested to demonstrate the design procedure with the proposed method. The numerical study shows that the combined use of finite element model and exact dynamic element model is very useful.

• Korean Journal of Agricultural Science
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• v.50 no.3
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• pp.457-468
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• 2023

The purpose of this study is to develop a high-speed combine harvester. The performance was evaluated by composing a dynamic simulation model of a threshing cylinder and analyzing the amount of threshed rice grain during threshing operations. The rotational speed of the threshing cylinder was set at 10 rpm intervals from 500 rpm until 540 rpm, based on the rated rotational speed of 507 rpm. The rice stem model was developed using the EDEM software using measured rice stem properties. Multibody dynamics software was utilized to model the threshing cylinder and tank comprising five sections below the threshing cylinder, and the threshing performance was evaluated by weighing the grain collected in the threshing tank during threshing simulations. The simulation results showed that section 1 and 2 threshed more grains compared to section 3 and 4. It was also found that when the threshing speed was higher, the larger number of grains were threshed. Only simulation was conducted in this study. Therefore, the validation of the simulation model is required. A comparative analysis to validate the simulation model by field experiment will be conducted in the future.

• Journal of the Korean Geosynthetics Society
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• v.17 no.1
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• pp.119-126
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• 2018

The ground cavity occurring in the downtown area is on the increase. However, when ground subsidence is occurred or a cavity that causes it to occur is found, time and economic difficulties are follwed in recovery. In advance, this study conducted to develop filling system for reinforcement material which is consist of polymer pouch and admixture as a new filler material. We developed a polymer pouch that is water soluble in the precedent study. Since the filling system is trenchless method and don't need any plant, it has time and economic benefits. This system uses air pressure to filling out cavity in a short time. We estimate this system with respect to filling speed and filling ratio by model experiment. In addition, we could confirm various filling condition using DEM Analysis. So, we could develop filling system and analysis it.

• Journal of Microbiology
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• v.43 no.6
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• pp.529-536
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• 2005

Viral infection causes stress to the endoplasmic reticulum (ER). The response to endoplasmic reticulum stress, known as the unfolded protein response (UPR), is designed to eliminate misfolded proteins and allow the cell to recover. The role of hepatitis C virus (HCV) non-structural protein NS4B, a component of the HCV replicons that induce UPR, is incompletely understood. We demonstrate that HCV NS4B could induce activating transcription factor (ATF6) and inositol-requiring enzyme 1 (IRE1), to favor the HCV subreplicon and HCV viral replication. HCV NS4B activated the IRE1 pathway, as indicated by splicing of X box-binding protein (Xbp-1) mRNA. However, transcriptional activation of the XBP-1 target gene, EDEM (ER degradation-enhancing $\alpha-mannosidase-like$ protein, a protein degradation factor), was inhibited. These results imply that NS4B might induce UPR through ATF6 and IRE1-XBP1 pathways, but might also modify the outcome to benefit HCV or HCV subreplicon replication.

• The Journal of Dong Guk Oriental Medicine
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• v.2 no.1
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• pp.107-125
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• 1993

This study was performed to investigate the effects of Gwaluzisiltang and Gwaluzisiltanggami on the intravascular coagulation. The experimental group divided two groups : one group was the intravascular coagulation induced by endotoxin in rats, another group was the formation of paw edema by contusion in rats, and then these rats were treated with liquid extract of Gwaluzisiltang(Sample I) and Gwaluzisiltanggami(Sample II), which were administered orally. Then the numbers of platelets, concentration of fibrinogen, Prothrombin time and FDP(fibrin-fibrinogen degradation Products)were measured. The results were as follows : 1. The effects of the Intravascular coagulation 1) Platelet was increased significantly in the sample I compared with control group. 2) Fibrinogen was increased significantly in the sample I compared with control group. 3) Prothrombin time was shortened significantly in the sample I and more shortened in the sample II compared with control group. 4) FDP was decreased significantly in the sample I and more decreased in the samplem II compared with control group. 2. The effect of the formation of paw edema by contusion in rats. 1) The rate of paw edem was decreased significantly after five hours in the sample I 2) Platelet was increased significantly in the sample I compared with control group. 3) Fibrinogen was decreased in the sample I and sample II compared with control group, but it is not significant 4) Prothrombin time was shortened significantly in the sample II compared with control group. According to the above results, it is considered that the Gwaluzisiltang and Gwaluzisiltanggami seem to be applicable disease related to thrombosis, because they obtained significant effects on the experimental method which are based on the oriental medical theory-the principle of phlegm and blood stasis have the same source and disease (痰瘀同源, 痰瘀同病).

• Nuclear Engineering and Technology
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• v.53 no.7
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• pp.2174-2183
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• 2021

Helium cooled solid breeder blanket as an important blanket candidate of the Tokamak fusion reactor uses ceramic pebble bed for tritium breeding. Considering the poor effective thermal conductivity of the ceramic breeder pebble bed, thin structure of tritium breeder pebble bed is usually adopted in the blanket design. The container wall has a great influence on the thin pebble bed packing structure, especially for the assembly of mono-sized particles, and thin pebble bed will appear anisotropic effective thermal conductivity phenomenon. In this paper, thin ceramic pebble beds composed of 1 mm diameter Li₄SiO₄ particles are generated by the EDEM 2.7. The effective thermal conductivity of different thickness pebble beds in the three-dimensional directions are analyzed by three-dimensional thermal network method. It is observed that thin Li₄SiO₄ pebble bed showing anisotropic effective thermal conductivity under the practical design size. Normally, the effective thermal conductivity along the bed vertical direction is higher than the horizontal direction due to the gravity effect. As the thickness increases from 10 mm to 40 mm, the effective thermal conductivity of the pebble bed gradually increases.