• The Journal of Information Systems
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• v.33 no.1
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• pp.91-114
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• 2024

Purpose The purpose of this study is to empirically investigate the factors that influence users' continuous intention to use ChatGPT based on the Expectation Confirmation Model(ECM). Drawing from the literature, this study identifies anthropomorphism and trust as key characteristics of generative AI and ChatGPT. Design/methodology/approach The research model was developed based on ECM and literature research to investigate the impacts of anthropomorphism and trust on continuous intention of using ChatGPT. In order to test the hypothese, a total of 193 questionnaires were collected and analyzed for the structural equation modeling with SmartPLS 4.0. Findings The study's findings show that all proposed hypotheses were supported, suggesting that the ECM is a valid framework for examining continuous intention of using ChatGPT. Moreover, the study stressed the crucial role of anthropomorphism in the model, showing the positive impact on expectation confirmation, perceived usefulness, and trust in ChatGPT. Also, trust positively affects perceived usefulness. These findings provide valuable insights for enhancing user satisfaction and continuous usage intention, serving as a foundation for development strategies for ChatGPT and similar AI-based systems.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.11 no.1
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• pp.105-129
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• 2007

Objectives: The purpose of this research is to obtain basic data about the effects of Constitution-Acupuncture (CA) based on Eight-Constitution Medicine (ECM) by the expert CA Oriental Medical Doctors. Methods: The resources were collected from the internet survey method. 35 samples were collected. The SPSS 13.0 for windows and Answer Tree 3.0 was used for statistical analysis. Results: The results from this research are as follow. 1. The motivation that apply ECM to clinic are 'Because ECM is effective for diagnosis, treatment and prevention against disease' 48.6% and 'Because CA therapy is effective' 25.7%. 2. The advantage that CA therapy compare to the other acupuncture therapy are 'Management and prevention against disease are available by ECM theory to a person who exact constitution is confirmed' 82.9%, 'CA therapy is superior in treatment of hard symptoms to treat by the other acupuncture therapy' 80%, 'Treatment effect is good' 77.1%, 'Needle manipulation of CA is simple comparatively' 57.1%, 'It is definite whether treatment effect is good or not' 54.3% and CA therapy is superior all in diseases of twelve category. 3. When the effects of CA is good, patients expressed much 'Eyesight lightened', 'Took deep sleep at night', 'Fatigue decreased', 'Body is light', 'Feelings became refreshing' as well as 'Symptoms were improved' and also physicians confirmed as those reactions whether treatment is effective. Conclusions: The research suggest that CA is effective therapy in clinic, and so further study is needed for CA therapy.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.33 no.4
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• pp.245-249
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• 2007

The alternation of extracellular matrix (ECM) protein in aging process is associated with symptoms such as wrinkling and loss of elasticity in skin. Now, the major target proteins for anti-aging have been metalloproteases and the structural proteins such as collagen and elastin. Recently, the interaction of cell and ECM proteins (collagen, fibrillin, and fibronectin) is reported to have an important role in survival, proliferation and tissue reconstruction. Fibronectin is a matrix adhesion protein which binds to collagen and integrin and degraded by serine proteases. It has been reported that fragments of fibronectin (Fn-fr's) were involved in matrix metalloproteases (MMPs) expression in osteoblast. But, the role of Fn-fr's in human skin and in skin cells has not been reported yet. Therefore, we investigated the differences of fibronectin fragmentation pattern between young and aged human skin, and demonstrated that the fragmentation of fibronectins is significantly increased in aged human skin. Also, treatment of Fn-fr's (70, 45 kDa) increased MMP-1 expression and MMP-2 activity in human dermal fibroblasts. Our results suggest that Fn-fr's as a potential new factor to accelerate skin aging.

• Molecules and Cells
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• v.41 no.12
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• pp.1016-1023
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• 2018

Regenerative orthopedics needs significant devices to transplant human stem cells into damaged tissue and encourage automatic growth into replacements suitable for the human skeleton. Soft biomaterials have similarities in mechanical, structural and architectural properties to natural extracellular matrix (ECM), but often lack essential ECM molecules and signals. Here we engineer mineralized polysaccharide beads to transform MSCs into osteogenic cells and osteoid tissue for transplantation. Bone morphogenic proteins (BMP-2) and indispensable ECM proteins both directed differentiation inside alginate beads. Laminin and collagen IV basement membrane matrix proteins fixed and organized MSCs onto the alginate matrix, and BMP-2 drove differentiation, osteoid tissue self-assembly, and small-scale mineralization. Augmentation of alginate is necessary, and we showed that a few rationally selected small proteins from the basement membrane (BM) compartment of the ECM were sufficient to up-regulate cell expression of Runx-2 and osteocalcin for osteoid formation, resulting in Alizarin red-positive mineral nodules. More significantly, nested BMP-2 and BM beads added to a non-union skull defect, self-generated osteoid expressing osteopontin (OPN) and osteocalcin (OCN) in a chain along the defect, at only four weeks, establishing a framework for complete regeneration expected in 6 and 12 weeks. Alginate beads are beneficial surgical devices for transplanting therapeutic cells in programmed (by the ECM components and alginate-chitosan properties) reaction environments ideal for promoting bone tissue.

• Communications of the Korean Institute of Information Scientists and Engineers
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• v.25 no.8 s.219
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• pp.32-35
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• 2007

• Journal of the Korean Institute of Telematics and Electronics A
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• v.32A no.11
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• pp.1-7
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• 1995

The problem of amplitude-and frequency-modulated waveforms is analyzed when a linearly polarized electromagnetic wave is scattered by a slowly rotating rotor with metal plates. ECM in conjunction with a quasi-stationary method is used to analyze the modulated waveforms. The modulated waveforms depend on the orientation and dimension of the object. its rotation speed, and very strongly on the incident and scattering directions. The modulate waveforms of a rotating non-skewed metal plate and a rotor with two blades are functions of twice the rotating frequency of those. Similar results are discussed for a rotating skewed metal plate, but the modulated waveforms is a function of the rotating frequency. Numerical results based on our ECM are presented and compared with those of Sikta's and PO solution.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2003.10a
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• pp.145-146
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• 2003

Overproduction of transforming growth factor (TGF)-$\beta$l has been implicated in the pathogenesis of fibrotic diseases. TGF-$\beta$l plays a crucial role in the accumulation of extracellular matrix (ECM) in human and experimental glomerular diseases. However, it remains unclear whether inhibition of TGF- $\beta$l overproduction would suppress TGF- $\beta$l induced ECM accumulation. To inhibit the overproduction of TGF- $\beta$l in experimental glomerulonephritis induced by anti-Thy 1.1 antibody, we introduced antisense oligodeoxynucleotides (ODN) fur TGF- $\beta$l into the nephritic kidney by the HVJ-liposome-mediated gene transfer method. (omitted)

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.1960_1961
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• 2009

본 논문에서는 PID, PWM, HSC, 컴퓨터와의 호스트 통신, 외부 DAC 인터페이스를 FPGA만을 이용하여 하나의 Chip에 구현하고 DC 서보 모터의 속도를 설정한 제어 상태로 안정화시킬 수 있는 시스템을 구현하고자 한다. 컴퓨터에서 설정한 설정치(SV)와 P, I, D의 이득 값을 호스트 통신으로 데이터 블록은 해당 블록으로 전달하며 DC 서보 모터의 엔코더에서 나오는 $90^{\circ}$ 위상차가 있는 2채널의 펄스는 HSC 블록을 거쳐 프로세스치(PV)를 생성 고 이로부터 얻어진 SV와 PV의 편차(E)를 산출한 후 PID 제어 동작을 수행한다. 그 결과인 조작치(MV)를 PWM 블록에 제공하여 실질적으로 DC 서보 모터를 구동하는 H-bridge 회로를 구동한다. 또한 FPGA 내부의 SV, PV, E, MV를 오실로스코프로 계측하기 위해 DAC 인터페이스 블록을 첨가 하여 외부 디지털 아날로그 변환기(DAC)를 제어 하였다.

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.1937_1938
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• 2009

이 논문에서는 1차원 혼돈맵들 중의 하나인 톱니맵을 8비트의 유한정밀도로 이산화시켜 설계하였고, 이 이산화된 톱니맵을 사용한 혼돈 2진 순서 발생기의 회로도도 제시하였다. 설계된 혼돈맵의 실제 구현은 이산화된 진리표로부터 얻어진 출력변수의 간략화된 부울함수에 따른 입력선과 출력선들의 정확한 연결만에 의해 실현하였다. 최대길이를 발생시키는 선형궤환시프트레지스터(mLFSR)에 의해 발생되는 난수성 2진 출력 순서들을 이산화된 톱니맵의 입력순서로 사용함으로써 결과적으로 최소 8배 더 긴 주기를 갖는 혼돈 2진 순서들을 발생시켰다.

• Journal of Animal Reproduction and Biotechnology
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• v.35 no.2
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• pp.113-118
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• 2020

Hepatic stellate cells (HSCs) play essential roles in normal and pathophysiological function in liver. In steady state, HSCs contribute to retinoid storage, immune tolerance, and extracellular matrix (ECM) homeostasis. Upon liver injury, they become activated and lead to morphological and functional changes. Studies have demonstrated that activation of HSCs by various stimuli such as toxins, microbial infection, or metabolic overload can promote the fibrotic changes in liver by production of ECM. Herein, we provide current knowledge about the basic characteristics of HSCs and the mechanism by which they are activated.