• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.125-126
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• 1998

Pulse conduction velocity is determined by areterial compliance, which is changed by lateral pressure of arterial wall. Hydrostatic pressure of the limb vessel is changed by body position, especially in elevated arm. The arterial pulse in the finger causes the blood volume to change, changing the optical density of the blood. Photoplethysmograph of index finger was obtained by LED and phototransistor. Pulse transmission time(PTT) was measured by the interval between the peak of ECG R wave and the peak of the finger plethysmogram. PTT was increased by upward position of arm, and decreased by downward position of the arm compared to horizontal position. This result suggests that relationship between finger plethysmography and postural change could be applied to evaluate clinical cardiovascular status.

• 대한의용생체공학회:의공학회지
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• 제18권1호
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• pp.17-24
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• 1997

We have developed a patient monitoring system including module-based bedside monitors, interbed network, central stations, clinical workstations, and DB servers. A bedside monitor with a color LCD can accommodate up to 3 module cases and 21 different modules. Six different physiological parameters of ECG, respiration, invasive blood pressure, noninvasive blood pressure, body temperature, and arterial pulse oximetry with plethysmoyaph are provided as parameter modules. In a single bedside monitor, modules and a module controller communicate with IMbps data rate through an intrabed network based on RS-485 and HDU protocol. At the same time, it communicates with other bedside monitors and central stations through interbed network based on 1 OMbps Ethernet and TCP/IP protocol. Central stations using 20" color CRT monitors can be connected with many bedside monitors and they display 18 channels of waveforms simultaneously. Clinical workstations are used mainly for the review of patient datE In order to accommodate more advanced data management capabilities such as 24-hour full disclosure, we have developed a relational database server dedicated to the patient monitoring system. Software for bedside monitor, central station, and clinical workstation fully utilizes graphical user interface techniques and all functions are controlled by a rotate/push button on the bedside monitor arid a mouse on the central station and clinical workstation. The entire system satisfies the requirements of AAMI and ANSI standards in terms of electrical safety and performances.nces.

• 대한치과마취과학회지
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• 제7권2호
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• pp.120-125
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• 2007

Background: Propofol has been used extensively for short-acting intravenous sedative agent during monitored anesthesia care (MAC). This study was designed to evaluate the safety and availability of MAC using propofol in implant surgery of the one-day admission patients. Methods: In this study, subjects were divided into two groups according to ASA physical status. The heart rate, blood pressure, peripheral oxygen saturation and ECG of a patient were estimated under MAC by an anesthesiologist and the vital signs were recorded in recovery room periodically afterwards. The subjective satisfaction with regard to outpatient ambulatory surgery under MAC procedure was evaluated the next day. Results: Systolic and diastolic blood pressure were significantly decreased during MAC in ASA I group, but other remarkable changes in vital sign were not observed. There was no significant difference in pain and anxiety level between ASA I and ASA II, III group. Satisfaction rate was high in both groups. Conclusion: Monitored-Anesthesia Care using propofol during implant surgery of the one-day admission patients might be safe and available procedure because heart rate, blood pressure and oxygen saturation are stable before and during surgery, and adequate control of pain and anxiety is supported.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 추계종합학술대회 B
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• pp.312-315
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• 2008

최근 유비쿼터스, RFID 및 근거리 무선통신 기술의 발전에 힘입어 의료분야에서도 이러한 기술을 이용하여 원격지에서 환자의 생체 신호와 각종 의료데이터를 무선으로 측정할 수 있는 시스템에 대한 많은 연구가 이루어지고 있다. 본 논문에서는 심전도(ECG), 혈압, 맥박 등의 생체신호 측정센서를 이용한 센서네트워크를 구축하여 u-Healthcare 시스템을 설계하고 구현하였다. 센서노드에서 게이트웨이를 경유한 생체신호는 헬스케어센터로 전송되며, 헬스케어센터에서 분석한 결과에 따라 환자에게 운동요법, 식이요법 등의 정보를 피드백하여 건강관리를 할 수 있게 하였다.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권8호
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• pp.443-451
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• 2003

Many attempts have been made for the health and lives of patients at a remote site. but little attention has been given to emergency system using wireless or other intelligent networks. In this paper, shown is a remote emergency system which can be used in an ambulance. It possibly gives a great help to the patients who may lose their lives, in other words, gives pre-hospital cure to them being sent to the hospital. Doctors or specialists are able to give a quick help which may give a new life to patients. This system deal with very important patient's data-ECG, SpO$_2$, blood pressure, biomedical signal data etc. - as other emergency system. A good performance better than other system is many but shortly spoken as follows. First, this system is user friendly system activated in windows 2000 environment. Second, MPEG4 and ECG data sent to the other station for specilists can give a pre-hospital cure to patients in advance. Third, there exist effective algorithms to operate this system. Fourth, this system has been made with software mostly, so this system can be easily embedded in IBM compatible computer. In addition to this performance, for the better and reliable system, various tests were proceeded and recursively tested. Tests were made in EV-DO wireless network and Local Area Network. This mobile-fixed remote emergency system using wireless network like EV-DO network will give a great usage to needed area.

• 대한약침학회지
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• 제19권3호
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• pp.197-206
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• 2016

Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery's pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written informed consent will be obtained from all participants. The participants will receive acupuncture once at ST36 on both sides. The radial arterial pulse waves will be measured on the left arm of the subjects by using an applicable pulse tonometric device (KIOM-PAS). On the right arm (appearing twice), electrocardiogram (ECG), photoplethysmogram (PPG), respiration and cardiac output (CO) signals, will be measured using a physiological data acquisition system (Biopac module), while the velocity of blood flow, and the diameter and the depth of the blood vessel will be measured using an ultrasonogram machine on the right arm (appearing twice). All measurements will be conducted before, during, and after acupuncture. The primary outcome will be the spectral energy at high frequencies above 10 Hz ($SE_{10-30Hz}$) calculated from the KIOM-PAS device signal. Secondary outcomes will be various variables obtained from the KIOM-PAS device, ECG, PPG, impedance cardiography modules, and an ultrasonogram machine. Discussion: The results of this trial will provide information regarding the physiological and the hemodynamic mechanisms underlying acupuncture stimulation and clinical evidence for the influence of acupuncture on the pressure pulse wave in the radial artery. Ethics and dissemination: This study was approved by the Institutional Review Board (IRB) of Kyung Hee University's Oriental Medical Center, Seoul, Korea (KOMCIRB-150818-HR-030). The study findings will be published in peer-reviewed journals and presented at national and international conferences. Trial registration number: This trial was registered with the Clinical Research Information Service (CRIS) at the Korea National Institute of Health (NIH), Republic of Korea (KCT0001663), which is a registry in the World Health Organization's (WHO's) Registry Network.

• 대한약리학회지
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• 제22권2호
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• pp.105-114
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• 1986

본 실험실에서는 민간요법으로 말라리아와 성병등의 치료제로 사용되어온 회양목(Buxus microphylla var. koreana Nakai)에서 steroid성 alkaloid인 cyclobuxine D와 nonalkaloid인 buxuletin을 분리하였다. Buxuletin의 가토에 있어서 이뇨작용에 대해서는 본 실험실에서 보고한바 있으며 cyclobuxine D의 약리작용에 대한 보고는 지금까지 전무한 상태이다. 본 실험에서는 새로운 항부정맥 약물의 밭견의 일환으로 cyclobuxine D의 적출 개구리 심장에 대한 작용과 마취시킨 흰쥐의 ECG와 심박동수에 대한 작용을 관찰하였다. Cyclobuxine D는 적출 개구리 심장에 대해 용량의존적 심근 수축력 감소를 나타냈으며 흰쥐에 있어서 현저한 심박동수 감소를 나타냈다. Cyclobuxine D는 흰쥐의 ECG에 있어서 PR interval과 P ${\alpha}T$ interval을 연장시키며, QRS complex와 PR interval의 심박동수에 대한 보상치인 PRc에 대해서는 고용량에서는 연장시키나 그 작용이 현저하지 않다. 이 결과로 보아 cyclobuxine D는 흰쥐의 ECG에서 A-V conduction과 ventricular depolarization에 주로 관여하는 것으로 사료 되며 이는 기존의 antiarrhythmic drugs과 비교해 볼 때 quinidine sulfate와 유사성이 있다고 추정된다.

• The Korean Journal of Physiology
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• 제18권1호
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• pp.67-79
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• 1984

고등학교(高等學校) 운동선수(運動選手)의 심폐기능(心肺機能)과 근전도(筋電圖) 혈액성분(血液成分)의 특성(特性)을 구명(究明)하고자 $16{\sim}19$세(歲)의 고등학생(高等學生) 선수군(選手群) 19명(名)과 비선수군(非選手群) 20명(名)을 대상(對象)으로 하여 실시(實施)한 본연구(本硏究)의 결과(結果)를 요약(要約)하면 다음과 같다. 1) 심전도시간간격(心電圖時間間隔)은 선수군(選手群)이 길었으며 특(特)히 R-R, Q-T 및 T-P간격(間隔)이 유의(有意)하게 길었다. 안정시(安靜時) 선수군(選手群)의 심박수(心搏數)는 비선수군(非選手群)에 비(比)해 서맥(徐脈)을 나타내었다. 심전도파고(心電圖波高)도 선수군(選手群)이 $Rv_5$파고(波高)와 $Tv_5$파고(波高)에서 유의(有意)하게 높았다. 2) 폐기능중(肺機能中)에 노력성호기량지수(努力性呼氣量指數)는 선수군(選手群)이 높았으며, 특(特)히 FEV 0.5초치(秒値)가 유의(有意)하게 높았고, 노력성폐류속(努力性肺流速)에서도 선수군(選手群)이 높았으며 특(特)히 PEF, FEF 25%, PIF 및 FEF $200{\sim}1200\;ml$ 치(値)가 유의(有意)하게 높았다. 3) 심변수(心辯數), 혈압(血壓) 및 호흡수(呼吸數)는 운동후(運動後) 유의(有意)하게 증가(增加)하였으며, 이중(中)에 심박수(心博數) 및 호흡수(呼吸數)는 비선수군(非選手群)이 더 증가(增加)하였는데 비(比)해 혈압(血壓)은 선수군(選手群)이 더 증가(增加)하였다. 4) 정귀혈(靜歸血)의 산소분압(酸素分壓)$(Pvo_2)$은 운동후(運動後) 감소(減少)하였고 탄산(炭酸)가스분압(分壓)$(Pvco_2)$는 증가(增加)하였으며, 양군(兩群)사이에는 별(別) 차이(差異)가 없었다. 5) 혈중(血中) glucose농도(濃度) 및 유산농도(乳酸濃度)는 운동후증가(運動後增加)하였고 특(特)히 혈중유산농도(血中乳酸濃度)가 유의(有意)하게 증가(增加)하였으며, 비선수군(非選手群)이 선수군(選手群)에 비(比)해 그 배가(培加)가 더 컸다. 6) 체전도파고(締電圖波高)가 운동부하(運動負荷)의 배(培)에 따라 계속증가(繼續增加)되었으며 이 중(中) 선수군(選手群)의 진폭(振幅)의 증가(增加)가 비선수군(非選手群)에 비(比)해 더 컸다.

• 한국정보기술응용학회:학술대회논문집
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• 한국정보기술응용학회 2005년도 6th 2005 International Conference on Computers, Communications and System
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• pp.335-338
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• 2005

In this paper, we propose a downlink power control scheme to apply in the unequal error protection multi-code CDMA mobile medicine system. The mobile medicine system contains (i) blood pressure and body temperature measurement value, (ii) ECG medical signals measured by the electrocardiogram device, (iii) mobile patient's history, (iv) G.729 audio signal, MPEG-4 CCD sensor video signal, and JPEG2000 medical image. By the help of the multi-code CDMA spread spectrum communication system with downlink power control scheme and unequal error protection strategy, it is possible to transmit mobile medicine media and meet the quality of service. Numerical analysis and simulation results show that the system is a well transmission platform in mobile medicine.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1994년도 춘계학술대회
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• pp.57-59
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• 1994

In this paper, we present the software part of the intelligent data processing unit (IDPU), which plays an important role in SiMACS. The software system processes ECG, EEG, EMG, blood pressure, respiration, temperature signals, and extracts some information about patient conditions. It displays the patient condition information and the signal data synchronously, and manages them together with other patient personal data in a network-based client/server environment. The software system is designed in an object-oriented paradigm, and implemented in C++ as a window-based application program.