• Title/Summary/Keyword: EC Strategy

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Tumor Markers for Diagnosis, Monitoring of Recurrence and Prognosis in Patients with Upper Gastrointestinal Tract Cancer

  • Jing, Jie-Xian;Wang, Yan;Xu, Xiao-Qin;Sun, Ting;Tian, Bao-Guo;Du, Li-Li;Zhao, Xian-Wen;Han, Cun-Zhi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10267-10272
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    • 2015
  • To evaluate the value of combined detection of serum CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS for the clinical diagnosis of upper gastrointestinal tract (GIT) cancer and to analyze the efficacy of these tumor markers (TMs) in evaluating curative effects and prognosis. A total of 573 patients with upper GIT cancer between January 2004 and December 2007 were enrolled in this study. Serum levels of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were examined preoperatively and every 3 months postoperatively by ELISA. The sensitivity of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were 26.8%, 36.2%, 42.9%, 2.84%, 25.4%, 34.6%, 34.2% and 30.9%, respectively. The combined detection of CEA+CA199+CA242+CA724 had higher sensitivity and specificity in gastric cancer (GC) and cardiac cancer, while CEA+CA199+CA242+SCC was the best combination of diagnosis for esophageal cancer (EC). Elevation of preoperative CEA, CA19-9 and CA24-2, SCC and CA72-4 was significantly associated with pathological types (p<0.05) and TNM staging (p<0.05). Correlation analysis showed that CA24-2 was significantly correlated with CA19-9 (r=0.810, p<0.001). The levels of CEA, CA19-9, CA24-2, CA72-4 and SCC decreased obviously 3 months after operations. When metastasis and recurrence occurred, the levels of TMs significantly increased. On multivariate analysis, high preoperative CA72-4, CA24-2 and SCC served as prognostic factors for cardiac carcinoma, GC and EC, respectively. combined detection of CEA+CA199+CA242+SCC proved to be the most economic and practical strategy in diagnosis of EC; CEA+CA199+CA242+CA724 proved to be a better evaluation indicator for cardiac cancer and GC. CEA and CA19-9, CA24-2, CA72-4 and SCC, examined postoperatively during follow-up, were useful to find early tumor recurrence and metastasis, and evaluate prognosis. AFP, TPA and TPS have no significant value in diagnosis of patients with upper GIT cancer.

Sensitivity of Botrytis cinerea Isolated from Infected Leaves of Ginseng to Tolyfluanid (Tolyfluanid에 대한 인삼 잿빛곰팡이병균의 감수성)

  • Kim, Joo-Hyung;Kim, Ga-Hye;Kim, Heung-Tae
    • The Korean Journal of Pesticide Science
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    • v.15 no.2
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    • pp.188-193
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    • 2011
  • Resistance monitoring for tolyfluanid was conducted over 2 years from 2005 to 2006 with 218 isolates of Botrytis cinerea obtained from infected plants of ginseng. All isolates of B. cinerea were divided into 3 groups such as highly sensitive (HS) group, sensitive (S) group and less sensitive (LS) group to tolyfluanid. HS group was defined as one showing $EC_{50}$ value less than $2.0\;{\mu}g\;mL^{-1}$. $EC_{50}$ value of S group ranged between $2.0\;{\mu}g\;mL^{-1}$ and $18.0\;{\mu}g\;mL^{-1}$, while that of LS group was more than $18.0\;{\mu}g\;mL^{-1}$ Among B. cinerea isolates tested in this study, 174 isolates were included into S group, while 22 isolates were done into HS group. The other isolates belonged to LS group. Botrytis cinerea isolates showed the high correlation of $EC_{50}$ value of mycelial growth with that of spore germination to tolyfluanid. This results could be used for the determination of fungicide resistance and the establishment of strategy for fungicide resistance management.

A study of distribution characteristics of unidentified particulate components in an urban area (도시환경의 총부유먼지 중 미지성분의 분포 특성에 대한 연구)

  • Kim, Yong-Hyun;Kim, Ki-Hyun;Park, Chan-Koo;Shon, Zang-Ho;Song, Sang-Keun
    • Analytical Science and Technology
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    • v.25 no.2
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    • pp.133-145
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    • 2012
  • The quantitative composition of total suspended particulates (TSP) in the atmosphere is identified to consist mainly of ions, organic carbon (OC), element carbon (EC), and metals. In terms of environmental analysis, the rest of the TSP composition may be defined as unknown fraction (${\Sigma}X$) which is yet difficult to analyze both quantitatively and qualitatively. In this study, the major components of TSP were measured at an urban residential area (Gang Seo) in Seoul, Korea from February to December 2009. These TSP data were analyzed in various respects to explain the relationship between known and unknown constituents. During this study period, TSP was comprised mainly of unknown compounds (48.6%) followed by ions, OC, EC, and metals. The results of this study indicate that the distribution of ${\Sigma}X$ exhibits a strong similarity with ${\Sigma}Anions$, as they both increase with increasing TSP levels. However, if the concentrations of ${\Sigma}X$ and ${\Sigma}Anion$ are normalized against TSP, they exhibit a strong inverse correlation with each other due probably to larges differences in solubility. To establish a better strategy for air quality control in urban atmosphere, more efforts are needed to characterize unidentified proportion of particulate matters.

The Rationalization of PDM in Pusan Port for the Period of Round Pacific Area (환태평양 시대의 부산항 물류산업 합리화)

  • Park, S. Y.;Park, C. S.
    • Journal of Korean Port Research
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    • v.6 no.1
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    • pp.93-110
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    • 1992
  • The most change in this century is supposed to be declination of ideology, and block of world economy. Addition to down full of cold war atmosphere around Northeast Asia, not only economic and social mood in this region is dramatically changed, but also it gave birth to the block of Northeast economy that accerlated new hub of world economy. According to dramatic change of economic surroundings the dynamic potential of growth in this region will be guided to enlarge inter-regional trade and increase volume of trade, thus suggests to grow steadily transportation. cargos in this region will have to arrange the system of delivery and inner transportation, accessary facilities, inter-regional harbors if North America and EC has connected easily. As have accerlated GATT and UR represented multilateralism and regionalism, it has regulated to increase trades of region due to relief of the trade barrier through specific areas has agreed with separately. The flow of regionalism of world economy has appeared to realize EC and NAFTA centered U.S.A, and also has presented to free trade region or one-size market agreement in Asia as APEC, EAEG in Malaysia, and etc. In defense to this block and internationalism of world economy, Pusan has to come forward to the hub of Northeast others has proposed a project to dominate the Northeast, Economy Association Agreement as Far East comprehensive development project in USSR, Hunchun development project in NK, and East Sea development project in PRC, Niigate regional development in Japan, Duman River development project in NK, and East Sea development project in Korea. As this exercise has proceed, Pusan also have arranged development strategy definitely and prepared provisions systematically. Engaging to participate center of delivery system is meant to be completed complex functions, namely the transfer storage processing & assembly function of international commodity. Pusan has ability to be terminal point of TSR. it had been connected to EC as the biggest economy block and TKR as complex transportation root to Far East, it would be the center of inground and seabase delivery terminal to Rotterdom as the biggest container pier and major piers to North-East and South East Asia. In order to provide a Role of 21 century's internationalization, Pusan has appealed to participate in management information research and development connected to Pohang-Ulsan-Changwon-Masan, and has utilized efficiently the resources such as man, material, money and information.

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Establishing the Education Strategy in strengthening Construction Management's ability in Large-scaled Construction Company (대형시공사의 사업관리 역량 강화를 위한 교육 전략 수립에 관한 연구)

  • Kim, Sang-Chul;Park, Chan-Jeong;Lee, Sang-Youb;Son, Jae-Ho
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.5
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    • pp.109-118
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    • 2007
  • It is related to launch the CM market and to increase the profit and entire ability in company that is enforcing the ability of construction management in large-scaled construction company. According to the CM market in U.S, CM market is increased with competing to the companies, that is E&C, general contractor, design firm, specialized CM firm. Also domestic market is similar to US market. In this situation, large-scaled construction companies are filled with construction management ability for competing with foreign companies and domestic CM firms. This paper suggests how to enforce the construction management ability through education, and shows the detailed education strategy considered the fields, divisions and positions.

Development of Continuous Monitoring Method of Root-zone Electrical Conductivity using FDR Sensor in Greenhouse Hydroponics Cultivation (시설 수경재배에서 FDR 센서를 활용한 근권 내 농도의 연속적 모니터링 방법)

  • Lee, Jae Seong;Shin, Jong Hwa
    • Journal of Bio-Environment Control
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    • v.31 no.4
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    • pp.409-415
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    • 2022
  • Plant growth and development are also affected by root-zone environment. Therefore, it is important to consider the variables of the root-zone environment when establishing an irrigation strategy. The purpose of this study is to analyze the relationship between the volumetric moisture content (VWC), Bulk EC (ECb), and Pore EC (ECp) used by plant roots using FDR sensors in two types of rockwool media with different water transmission characteristics, using the method above this was used to establish a method for collecting and correcting available root-zone environmental data. For the experiment, two types of rockwool medium (RW1, RW2) with different physical characteristics were used. The moisture content (MC) and ECb were measured using an FDR sensor, ECp was measured after extracting the residual nutrient solution from the medium using a disposable syringe in the center of the medium at a volumetric moisture content (VWC) of 10-100%. Then, ECb and ECp are measured by supplying nutrient solution having different concentration (distilled water, 0.5-5.0) to two types of media (RW1, RW2) in each volume water content range (0 to 100%). The relationship between ECb and ECp in RW1 and RW2 media is best suited for cubic polynomial. The relationship between ECb and ECp according to volume moisture content (VWC) range showed a large error rate in the low volume moisture content (VWC) range of 10-60%. The correlation between the sensor measured value (ECb) and the ECp used by plant roots according to the volumetric water content (VWC) range was the most suitable for the Paraboloid equation in both media (RW1, RW2). The coefficient of determination the calibration equation for RW1 and RW2 media were 0.936, 0.947, respectively.

Source Identification and Estimation of Source Apportionment for Ambient PM10 in Seoul, Korea

  • Yi, Seung-Muk;Hwang, InJo
    • Asian Journal of Atmospheric Environment
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    • v.8 no.3
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    • pp.115-125
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    • 2014
  • In this study, particle composition data for $PM_{10}$ samples were collected every 3 days at Seoul, Korea from August 2006 to November 2007, and were analyzed to provide source identification and apportionment. A total of 164 samples were collected and 21 species (15 inorganic species, 4 ionic species, OC, and EC) were analyzed by particle-induced x-ray emission, ion chromatography, and thermal optical transmittance methods. Positive matrix factorization (PMF) was used to develop source profiles and to estimate their mass contributions. The PMF modeling identified nine sources and the average mass was apportioned to secondary nitrate (9.3%), motor vehicle (16.6%), road salt (5.8%), industry (4.9%), airborne soil (17.2 %), aged sea salt (6.2%), field burning (6.0%), secondary sulfate (16.2%), and road dust (17.7%), respectively. The nonparametric regression (NPR) analysis was used to help identify local source in the vicinity of the sampling area. These results suggest the possible strategy to maintain and manage the ambient air quality of Seoul.

Logistics Strategy of Promotion for the B2B EC (기업간 전자상거래 활성화를 위한 물류혁신전략)

  • Lee, Kwang-Beom
    • International Commerce and Information Review
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    • v.3 no.1
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    • pp.197-223
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    • 2001
  • 최근 B2B 전자상거래 확산에 따른 물류문제를 해결하고 오프라인 물류와의 차별화롤 시도하기 위한 목적으로 다양한 물류측면의 대안이 제시되고 있다. 먼저 물류산업 자체의 e-business화를 추진함으로 기존 물류체계에서의 고비용 문제, 책임 소재가 불분명한 서비스 문제를 해결하고 운송정보의 실시간 제공을 통한 발주자, 화주자 간의 긴밀한 커뮤니케이션 형성과 해외시장을 겨냥한 글로벌 물류체계를 구축해야 한다. 다음으로 물류업종의 지나친 세분화, 기존 물류업체의 영세성과 혁신마인드의 부족, 그에 따른 제조 유통업체의 경쟁적 자가물류 확충의 악순환으로 제3자 물류시장 성장기반이 제한되어 오는 등 구조적인 문제점을 극복하기 위하여 주요 운송업체가 영세한 화주나 창고관리 위탁업무까지 대행하여 주는 지금까지의 제3자 물류 체제에서 대기업이 물류시장에 새롭게 진출하면서 사이버 물류시스템을 기반으로 기존 주요 운송업계와 VAN 사업자가 장악하고 있는 물류정보 서비스를 주도하는 제4자 물류체제로의 전환이 요구된다. 왜냐하면, SCM과 전자상거래 환경 하에서는 공급 망 내의 물류를 최적화하여 기업의 경쟁력을 강화하기 위해서 기능적 아웃소싱의 단계를 거쳐 물류기능의 통합과 운영의 자율권이 증대, 전체적인 공급연쇄 솔루션을 제공하는 서비스 제공자와 함께 기업의 경영자원, 능력, 기술을 관리하고 결합하는 공급연쇄 통합자로서 제4자 물류가 필요하기 때문이다. 이와 같은 제4자 물류체제가 본격 형성될 경우 물류정보와 인프라가 복잡하게 업혀있는 기존 물류산업이 재편되고, 특화된 물류솔루션을 바탕으로 한 산업별 물류체제 구축이 가속화될 것으로 예견되며, 일반기업 입장에서 물류부문의 아웃소싱이 촉진되어 물류산업기반이 확충될 수 있을 것이다.

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Operation Strategy for Electronic Commerce Promotion Base on Common Mechanic Industry (ASP기반으로 한 기계산업체간의 성공적 전자상거래 구축을 위한 전략연구)

  • Jeong, Sei-Hyun
    • Journal of Information Technology Services
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    • v.1 no.1
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    • pp.81-117
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    • 2002
  • The generalization of Internet use has been spreaded all over the world and impacted company to introduce intranet and extranet for their operation which dealt with electronic commerce. For these reason, endeavor of implementation of web site system is promotioned and enhanced the possibility of adaptation range for the view of company. Dramatic competition which company faced with the use of internet and request from all over the world made company brought company to various and different type of level. It is necessary to develop website system with experty knowledge to satisfy customer needs. To deal with this situation, works from the level of government should proposed to spread whole country business which propelled through kyungnam mechanic industry information promotion center. With strategic proposal concerning district characteristics to adapt electronic commerce successfully, information promotion should performed. Support of government is needed continuously to realize infra of ASP composed of 4,877 mechanic industry company. It might be possible to deal with international rapid change with cooperation of company and government related department.

Invulnerability analysis of nuclear accidents emergency response organization network based on complex network

  • Wen Chen;Shuliang Zou;Changjun Qiu;Jianyong Dai;Meirong Zhang
    • Nuclear Engineering and Technology
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    • v.56 no.8
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    • pp.2923-2936
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    • 2024
  • Modern risk management philosophy emphasizes the invulnerability of human beings to cope with all kinds of emergencies. The Nuclear Accidents Emergency Response Organization (NAERO) of Nuclear Power Plant (NPP) is the primary body responsible for nuclear accidents emergency response. The invulnerability of the organization to disturbance or attack from internal and external sources is crucial in the completion of its response missions, reduction of severity of accidents, and assurance of public and environmental safety. This paper focused on the NAERO of a certain NPP in China, and applied the complex network theory to construct the network model of the organization. The topological characteristics of the network were analyzed. Four importance evaluation indexes of network nodes including Degree Centrality (DC), Betweeness Centrality (BC), Closeness Centrality (CC) and Eigenvector Centrality (EC), along with Pearson coefficient correlation among the indexes were calculated and analyzed. Size of the Largest Connected Component (LCC) and Network Efficiency were used as measures regarding the invulnerability of the network. Simulation experiments were conducted to assess the invulnerability of network against various attack strategies. These experiments were conducted both in the absence of node protection measures and under protection measures with different node protection rates. This study evaluated the invulnerability of the NAERO network, and provided significant decision-making basis for the enhancement of the network's invulnerability.