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A Study on the Estimation of Limits to Life Expectancy (한국인 기대여명의 한계추정에 관한 연구)

  • 천성수;김정근
    • Korea journal of population studies
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    • v.16 no.2
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    • pp.65-83
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    • 1993
  • The purpose of this study is estimate limits of Korean life expectancy at birth by 'Gompertz growth curse Model', 'Cause-Elimination Model' and Multidimensional models of Senescencee and Mortality'. Data used in Gompertz curve were obtained from all life tables published from 1905 to 1990 in Korea, and life expectancies at birth of eighteen groups were selected at five-year interval in consideration of time-series changes. Data used in Cause-Elimination Model are 'Cause of Death statistics in 1991' published in 1992 by National Bureau of Statistics of Korea and 'life table of 1989' published in 1990 by National Bureau of Statistics, Economic Planning Board of Korea. The materials are all classifiable death data, 119, 253 cases of male and 82, 420 cases of female, which is from 1991 Causes of Death statistics. The cases of death analyzed belong to one of 8 categories; i.e., Infectious and Parasitic Diseases(001-139; with notation of Infectious Diseases), Malignant Neoplasms(140-208), Hypertensive Diseases(401-405), Ischemic Heart Dieases and Diseases of Pulmonary Circulation and Other Forms of Heart Diseases(410-429;with notation of Heart Disease), Cerebrovascular Diseases(430-438), Chronic Liver Diseases and Cirrhosis(571; with notation of Liver Diseases), Injury and Poisoning(800-999) and all other disease. Data used in 'Multidimensional models of senescence and mortality' were life table of 1989 published by National Bureau of statistics, Economic Planning Board of Korea and life table of 1970, 1978-79, 1983, 1985 and 1987. The major findings may be summarised as follows: 1. Estimate equations of Gompertz growth curve using life expectancy at birth during the 1905-1990 period are as the following. Male : y = 88.047697 $\times$ $0.199690^{0.903381x}$ Female : y = 95.632828 $\times$ $0.199690^{0.903381x}$ Limits of life expectancy at birth, which were estimated by Gompertz growth curve, are 88.05 for male and 95.63 for female. 2. The effect on life expectancy at birth eliminationg all causes death is 14.04 years(for male) and 10.86 years(for female). Astonishingly, eliminating the malignant neoplasms increase life expectancy at birth by 2.85 years for male 2.03 years for female in 1991. In table 8 we show the effect on life expectancy at birth of separately eliminating each of the 8 categorical causes of death. The theoretical limit to life expectancy by Cause-Elimination Model is 80.96 for male and 85.82 for female. 3. If the same rate of delay [0.376 year(male), 0.435 year(femable) per calendar year] continued, then life expectancy at birth would reach 74.82(male) years and 84, 10(female) years in 2010. With 14.04-years(male) and 10.86-years(female) effect attributable in 2010 would be 88.86 years(male) and 94.96(femable) years. 4. 'Multidimensional models of senescence and death' permits calculations of the value of the attribution coefficient (B), percent of loss per year of physiologic function. The results of Ro and B during the 1970-1989 period are listed in table 9. Estimate of limit to Korean life expectancy at birth by 'Multidimensional models of senescence and death' is 99.47 years for male and 104.74 years for female in 1989.

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Surface Sterilization Effect of Electrolyzed Acid-water on Vegetable (전해 산화수의 채소류 표면 살균 효과)

  • Jung, Sung-Won;Park, Kee-Jai;Park, Kyung-Jo;Park, Byoung-In;Kim, Young-Ho
    • Korean Journal of Food Science and Technology
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    • v.28 no.6
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    • pp.1045-1051
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    • 1996
  • The influence of electrolyzed acid-water (oxidation-reduction potential (ORP): above 1,150 mV, pH : 2.5) on the survival of some microorganisms was investigated. It was observed that the ORP of electrolyzed acid-water was kept at the level of above 1,000 mV for 15 days at room temperature. Escherichia coli. Salmonella typhi, Staphylococcus aureus and Saccharomyces cerevisiae were not detected after 10 to 40 min in electrolyzed acid-water. However, Bacillus cereus showed higher tolerance to electrolyzed acid-water than other test microorganisms. After 60 min of inoculation, only 0.4% of initial population remained. The investigation of surface sterilization effect on some vegetables was carried out too. Total count of cabbage, Chinese cabbage and kale were reduced to below 3% of initial count, and no coliform was detected after 20 to 60 min of immersion in 5 volumes of electrolyzed acid-water. In the lettuce, total and coliform counts were reduced to 90% and 2% of initial population. This study shows that the electrolyzed acid-water has a potential for the sterilization of food products such as vegetables and fruits which cannot be thermally sterilized.

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A Survey to Improve the Green Building Certifications Responding to Climate Change: Focused on the External Environment of Housing (기후변화에 대응한 녹색건축인증기준 개선을 위한 조사연구: 공동주택 외부환경을 중심으로)

  • Kwon, Hyuck-Sam;Kim, Ji-Hyeon;Kim, Jung-Gon
    • Land and Housing Review
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    • v.4 no.4
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    • pp.435-447
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    • 2013
  • This study aims to propose basic data for improvements that can actively respond to climate change in the Green Building Certifications that came into effect in March 2013, including the analysis of evaluation criteria and applications. In response to climate change, Green Building Certifications in developed countries such as BREEAM(UK), LEED(USA), DGNB(Germany), and CASBEE(Japan), have been extended to the neighborhood unit or city levels, i.e., BREEAM Communities, LEED Neighborhood Development, DGNB Stadtquartiere, CASBEE Urban Development. On the other hand, for the Green Building Certifications in Korea, some criteria such as indoor environment and energy have been given more emphasis than others such as external environment(land use, traffic, ecological environment). In addition, results from the analysis of the evaluation scores on the external environment of 79 housing complexes show that the score on the indoor environment and energy determines the evaluation grade, whereas the score on the external environment is less weighted and has less impact. Therefore, the new evaluation system for the Green Building Certifications responding to climate change should be extended from building level to urban district levels.

Analysis of Beach Gravels, the Weaver Peninsula, King George Island, Antarctica (남극 킹 죠지섬의 위버 반도 해빈자갈에 관한 연구)

  • 박용안;최문영;고영이
    • The Korean Journal of Quaternary Research
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    • v.5 no.1
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    • pp.47-61
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    • 1991
  • Textural analysis of gravels of raised beach (old beach) in the Weaver Peninsula, King George Island, Antarctica has been carried out as a first part study among 20 other sites surveyed in the Weaver Peninsula and Barton Peninsula, King George Island. The raised beach described as WP-5 in this paper is 3.95 m higher than the present beach in elevation. And it is described as old beach. The beach shows typical subenvironment, that is, beach berm and beach face. Mean size, mean roundness and mean sphericity of gravels from beach berm are -4.10ø, 0.44 and 0.66 respectively. However, mean size, mean roundness and mean sphericity from beach face are -4.23ø, 0.41 and 0.67 respectively. In particular, it seems to be worthy to note the differences of textural parameters between Antarctic glacio-marine beach gravels and temperate and normal marine beach gravels. Under such conception the present study wishes to show only textural parameters, i.e., size, roundness, sphericity and shape obtained from the analysis of Antarctic glacio-marine beach gravels.

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The Taxonomic Consideration of Leaf Epidermal Microsturcture in Glechoma L. (Nepetinae, Lamiaceae) (긴병꽃풀속(Glechoma L., 꿀풀과)의 잎표피 미세구조에 대한 분류학적 검토)

  • Jang, Tae-Soo;Hong, Suk-Pyo
    • Korean Journal of Plant Taxonomy
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    • v.37 no.3
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    • pp.239-254
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    • 2007
  • A comparative micromorphological study was examined on the leaves of the genus Glechoma and related genera (Nepetinae, Lamiaceae) by scanning electron microscopy (SEM) in order to evaluate their significance in the taxonomy. The leaves of taxa Marmoritis, Nepeta sect. Glechomanthe, G. hederacea var. longituba (Korea) are revealed amphistomatic type, while the remnants of taxa had hypostomatic type. The size range of the guard cells is $12.50-28.75{\times}9.17-21.25{\mu}m$: the smallest one was found in M. pharicus ($12.50-15.83{\times}9.17-11.25{\mu}m$), while the largest one was measured to G. hederacea var. longituba (Korea: $28.75-28.88{\times}21.25-21.38{\mu}m$). The stomatal type of genera Agastache, Dracocephalum was mostly diacytic, however for the rest rarely together with anisocytic and anomocytic, except G. hederaca var. longituba (Korea), Meehania urticifolia by having combined with diacytic and anomocytic. The shapes of epidermal cells are differ from in abaxial and adaxial side, and dived with two types (e.g., platelet, stripe pattern). Five types (three glandular, two non-glandular hairs) of trichomes are distributed in leaves. Among trichomes, long and stalk capitates glandular trichome, subsessile glands are different from studied taxa so that leaf micromorphological characters are significance features in the taxonomy.

The effect of artemisinin on the rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice (개똥쑥에서 분리(分離)된 artemisinin이 가토(家兎) IgG에 의해 유발(誘發)된 생쥐의 현독성(賢毒性) 혈청사구체현염(血淸絲球體賢炎)에 미치는 영향(影響))

  • Zhu, Quan
    • Journal of Haehwa Medicine
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    • v.4 no.2
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    • pp.335-336
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    • 1996
  • Artemisinin, a new antimalarial to treat patients infected with strains of Plasmodium jalciparum, derived from the plant Artemisia annua Linn, has immunopharmacologic actions such as enhence the PHA -induced lymphocyte transformation rate, increased the weight of spleen but reduced the weight of thymus, reduced phagocytic function of peritoneal macrophage, remarkably reduced the level of serum IgG and hemolysin fonning capacity (sentitized with SRBC), inhibited the activity of Ts cells of donor mice by supraoptimal immunuization(SOI), but enhenced activity of Ts cells of recipient mice by SOI. These results suggested that Ts cells may be the target cells of artemisinin. To the serum complement C3 level of plasmodium berghei-infeted mice, artemisinin (i. m,) could remarkly increase it. The artemisinin also obviously reduced the prostaglandin E(PGE) in the mouse hind paw swelling induced by carrageenin. Numerous studies have demonstrated that pharmacologic doses of PGE attenuate the development of immunocomplex nephritis. Some autologous immune mechanisms may be invoolved In the pathogensis of some types of glomurulonephritis. Glomerular abnormalities can be induced in animals by variety of immunological manipulations. The resulting disorder has many clinical and pathogical similarities to the disease in human. Our purpose was therefore to test the ability of the artemisinin to lessen the severity of rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice model. Mice which had treated with rabbit IgG and NTS, administrated with saline, showed Significant inceases of urinary protein, cholesterol level, and decrease of serum albumin in NS group. On the contrary, By i.g. adminstration of artemisinin at dose of 12.5, 25 and 50 mg/kg for 14 days after NTS injection, shown that artemisinin inhibited the nephritic changes in some parameters by means of urinary protein(p<0.05, p<0.01) and serum choleterol(p<0.05, p<0.01) and albumin (p<0.05, p<0.01), blood urea nitrogen (p<0.05, p<0.01), serum albumin(p<0.05, p<0.01); Cyclophosphamide(i.p. 10mg/kg for 14d) had almost same effect as the artemisinin had. Morphological studies shown that The picture of kidney from the mouse with NTS-nephritis accerated with rabbit IgG, treated with i.g. saline as the control, the mesangiocapillary were enlarged and proliferated; There were inflammatory cells infiltrating around the glomeruli; The ethelial cell were proliferated in the wall of Bowman's capsule. Histopatholological picture of kidney from the NTS-nephritis accerated with rabbit IgG mouse treated with i.p. 10mg/kg cyclophosphamide as the positive control. No siginicant histopathological evidence were found. Treaded with i.p. 12.5mg/kg artemisinine, the picture shown that mesangiocapillary were lightly proliferated; There were inflammatory cells infiltrating around the glomeruli; Treaded with i.p. 25mg/kg artemisinine, The picture shown that the mesangiocapillary were lightly proliferated; Treaded with i.p. 50mg/kg artemisinine, The picture shown that both the mesangiocapillary proliferated and the inflammatory cells infiltrating around the glomeruli are less than treated with saline, 12.5 and 25 mg/kg artemisinine. On the basis of these studies we conclude that the artemisinin can relieve pathological change caused by NTS-nephritis aacerated with rabbit IgG.

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Anti-oxidant and Anti-inflammatory Effects of Acanthopanacia Cortex Hot Aqueous Extract on Lipopolysaccharide(LPS) Simulated Macrophages

  • Jo, Na Young;Roh, Jeong Du
    • Journal of Acupuncture Research
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    • v.31 no.1
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    • pp.131-137
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    • 2014
  • Objectives : This study is to investigate the effects of Acanthopanacis Cortex hot aqueous extract on nitric oxide(NO), prostaglandin E2(PGE2) production and DPPH(1,1-diphenyl-2-picryl hydrazyl) radical scavenging activity in macrophages. Methods : Acanthopanacis Cortex(200 g) was heated at $100^{\circ}C$ with distilled water(2 L) for 4hrs. The extract was filtered and concentrated to 100 ml using a rotary evaporator and was frozen at $-80^{\circ}C$, then was freeze-dried. The RAW 264.7 macrophages were subcultured. In order to evaluate cytotoxicity, MTT assay was performed. Experimental groups were divided into five(control, AC 25, 50, 100 and 200 ${\mu}g/ml$) and we measured cytotoxicity. The concentrations of NO were preprocessed by Griess assay. The RAW 264.7 macrophages was pretreated by 10 ${\mu}g/ml$ LPS and experimental groups were divided into five and we measured NO production. The concentrations of $PGE_2$ were measured by enzyme immunoassay. The RAW 264.7 macrophages was pretreated by 10 ${\mu}g/ml$ LPS. Experimental groups were divided into five and we measured $PGE_2$ production. Antioxidant activity was measured by the DPPH method. experimental groups were divided into four(AC 25, 50, 100 and 200 ${\mu}g/ml$) and we measured DPPH radical scavenging activity. Results : 1. Viability of RAW 264.7 macrophages did not significantly decrease in 25, 50 and 100 ${\mu}g/ml$ Acanthopanacis Cortex hot aqueous extract compared to control group. 2. NO production in LPS-stimulated RAW 264.7 macrophages significantly inhibited in 100, 200 ${\mu}g/ml$ Acanthopanacis Cortex hot aqueous extract compared to control group. 3. $PGE_2$ production in LPS-stimulated RAW 264.7 macrophages significantly inhibited in 100, 200 ${\mu}g/ml$ Acanthopanacis Cortex hot aqueous extract compared to control group. 4. DPPH radical scavenging capability of Acanthopanacis Cortex hot aqueous extract in RAW 264.7 macrophages had the high level in 100, 200 ${\mu}g/ml$. Conclusion : According to the results, Acanthopanacis Cortexx hot aqueous extract has ability to suppress NO, $PGE_2$ production and improve DPPH free radical scavenging activity. So Acanthopanacis Cortex hot aqueous extract may have an anti-inflammation effect and antioxidant activity.

DISTRIBUTION CHARACTERISTICS OF NUTRIENTS IN CHINESE BOHAI SEA

  • Li, Zhengyan;Gao, Huiwang;Bai, Jie;Shi, Jinhui
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2001.11a
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    • pp.19-29
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    • 2001
  • Nutrients are key environmental factors in marine ecosystem. They limit algal growth when at low concentrations and cause algal bloom when at high contents. They also control the growth and succession of many other biota including bacteria and zooplankton, either directly or indirectly. Nutrient contents therefore affect both the structure and functions of marine ecosystem. To study the contents and distribution of nutrients in Chinese Bohai Sea, two cruise surveys were undertaken in August 2000 (summer) and January 2001 (winter), respectively. A total of 595 water samples were collected from 91 sites. After collection the samples were transported to the laboratory and five nutrients, i.e., nitrate, nitrite, ammonia, phosphate and silicate, were analyzed. The results showed that tile average concentration of total inorganic nitrogen (TIN) in Bohai Sea in winter (6.5293.717 ${\mu}$mol$.$l$\^$-1/) was significantly higher than that in summer (3.717 ${\mu}$mol$.$l$\^$-1/). The phosphorus concentration in winter (0.660 ${\mu}$mol$.$l$\^$-1/) was also significantly higher than that in summer (0.329 ${\mu}$mol$.$l$\^$-1/). Mean silicate concentration in winter (7.858 ${\mu}$mol$.$l$\^$-1/) was not significantly different from that in summer (7.200 ${\mu}$mol$.$l$\^$-1/). Nutrients also varied considerable among different areas within Bohai Sea. TIN concentration in Laizhou Bay (4.444 ${\mu}$mol$.$l$\^$-1/), for example, was significantly higher than those in Bohai Bay (2.270 ${\mu}$mol$.$l$\^$-1/) and Bohai Straight (2.431 ${\mu}$mol$.$l$\^$-1/), which probably reflects tile discharge of large amounts of nitrogen into Laizhou Bay via Yellow River. The nutrients also showed vertical distribution pattern. In summer, nutrients in bottom layer were generally higher than those in surface and medium layers. In winter, however. nutrients in different layers were not significantly different Compared with historic data, TIN contents increased continuously since early 1980s, phosphorus arid silicone contents, nevertheless, fell down to some degree. Based on atomic ratios of different nutrients, nitrogen is still the main limiting factor for algal growth in Bohai Sea.

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The Effect of composite Graft of allogenic DFDB and Calcium Sulfate with and without Calcium Sulfate barrier in Periodontal 1 wall intrabony defects in Dogs (성견 1면 골내낭에서 탈회 냉동 건조골과 calcium sulfate 혼합 이식 및 calcium sulfate 차단막 사용이 치주조직 치유에 미치는 영향)

  • Moon, Hee-Il;Cho, Kyoo-Sung;Chai, Jung-Kiu;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.28 no.2
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    • pp.219-237
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    • 1998
  • Numerous bone graft materials have been used in Periodontics, in an attempt to reach the main goal of periodontal therapy, i.e. the regeneration of periodontal tissue lost due to destructive periodontal diseases. The present study investigates the effect of composite graft of DFDB and Calcium sulfate with and without Calcium sulfate barrier in Periodontal 1-wall intrabony defects in dogs. Following the initiation of general anesthesia by I.V. administration of 40mg/Kg of Pentobabital, second premolar was extracted and full thickness flap elevated. The crown portion of premolars was removed. Exposed root canals were sealed with Caviton and covered completely with flap. After the healing period of 8 weeks, the surgical sites were re-opened and 1-wall intrabony defects were created, and treated with flap operation alone(control group), with composit graft of 80% DFDB and 20% Calcium sulfate(Experimental group 1), with composite graft of DFDB and calcium sulfate with calcium sulfate membrane( Experimental group 2). Healing response was histologically observed after 8 weeks and the results were as follows : 1. New bone formation was 70 % in the control group, 93 % in the Experimental group I, 89 % in the Experimental group II. There was a no differences between Experimental groups. 2. New cementum formation was not significantly different between control and two Experimental groups. 3. The length of connective tissue adhesion was 30 % in the control, 7% in the Experimental group I and 11 % in the Experimental group II. 4. After 8weeks, calcium sulfate was completely resorbed, while DFDB particle remained. These results suggest that the use of composite graft of allogenic DFDB and Calcium sulfate with and without Calcium sulfate barrier in periodontal 1 wall intrabony defects have little effect on connective tissue adhesion, but has beneficial effect on new alveolar bone and new cementum formation, and prevent downgrowth of epithelium and connective tissue effectively.

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Analyzing Korean Pre-service Biology Teachers' Understanding of the Concept of Natural Selection in Comparison with Chinese, American, and German Biology Majors (중국, 미국, 독일의 생물전공자와 비교한 한국 생물예비교사의 자연선택개념 이해 수준 분석)

  • Ha, Minsu
    • Journal of The Korean Association For Science Education
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    • v.36 no.5
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    • pp.729-737
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    • 2016
  • Natural selection is the core idea of evolution that pre-service biology teachers need to understand to solve diverse biological problem. This study aims to investigate the level of Korean pre-service biology teachers' understanding of natural selection by comparing their knowledge with their Chinese, American, and German biology major undergraduate counterparts. In particular, this study focuses on two conceptual components of natural selection (i.e., ecology and genetics). This study used a total 1226 pre-service biology teachers and biology majors' data. The instrument measuring the understanding of natural selection concepts was Conceptual Inventory of Natural Selection, which consists of ten ecology concept items and ten genetics concept items. The Rasch model analysis, multivariate analysis of variance, and univariate analysis of variance were used for the statistical tests. The result reveals that the level of Korean pre-service biology teachers' understanding of natural selection were similar with Chinese undergraduates' understanding and significantly lower than American and German undergraduates.' In the first year student data, the level of genetics concept of Korean pre-service biology teachers were significantly lower than Chinese and German students. In the fourth year student data, the level of ecology concept of Korean pre-service biology teachers were significantly lower than American and German students. Based on these results, the ecology concept education and balanced natural selection concept education are discussed.