• 한국자동차공학회논문집
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• 제22권3호
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• pp.250-256
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• 2014

EV(Electric Vehicle) has many benefits such as prevention of global warming and so on. But due to driving source changing from combustion engine to battery and e-motor, new R&D difficulties have arisen which changing of desired vehicle performance and multidisciplinary design constraints by means of strong coupled multi-physics domain problems. Additionally, dynamics performances of EV becomes more important due to increasing customer's demands and expectations for EV in compare with internal combustion engine vehicle. In this paper suggests model based development platform of EV through integrated simulation environment for improving analyse & design accuracy in order to solve multi-physics problem. This simulation environment is integrated by three following specialized simulation tools IPG CarMaker, AVL Cruise, DYMOLA that adapted to each purpose. Furthermore, control algorithm of TV(Torque Vectoring) system is developed using independent driven e-motor at rear wheels for improving handling performance of EV. TV control algorithm and its improved vehicle performances are evaluated by numerical simulation from standard test methods.

• Advances in aircraft and spacecraft science
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• 제9권3호
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• pp.169-193
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• 2022

By the present paper, both experimental and analytical models have been proposed to study the vibration behavior of partially bio-sourced sandwich panel with orthogonally stiffened core. For a variable mass fraction of Alfa fibers from 5% to 15%, impregnated in a Medapoxy STR resin, this panel were manufactured by molding the orthogonally stiffened core then attached it with both skins. Using simply supported boundary conditions, a free vibration test was carried out using an impact hammer for predicting the natural frequencies, the mode shapes and the damping coefficient versus the fibers content. In addition, an analytical model based on the Higher order Shear Deformation Theory (HSDT) was developed to predict natural frequencies and the mode shapes according to Navier's solution. From the experimental test, we have found that the frequency increases with the increase in the mass fraction of the fibers until 10%. Beyond this fraction, the frequencies give relatively lower values. For the analytical model, variation of the natural frequencies increased considerably with side-to-thickness ratio (a/H) and equivalent thickness of the core to thickness of the face (h_s/h). We concluded that, the vibration behavior was significantly influenced by geometrical and mechanical properties of the partially bio-sourced sandwich panel.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제18권1호
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• pp.89-104
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• 2024

Cloud-based e-learning (CBEL) represents a promising technological frontier. Existing literature has presented a diverse array of findings regarding the determinants that influence the adoption of CBEL. The primary objective of this study is to conduct an exhaustive examination of the available literature, aiming to determine the key predictors of CBEL utilization by employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. A comprehensive review of 35 articles was undertaken, shedding light on the status of CBEL as an evolving field. Notably, there has been a discernible downturn in related research output during the COVID-19 pandemic, underscoring the temporal dynamics of this subject. It is noteworthy that a significant portion of this research has emanated from the Asian continent. Furthermore, the dominance of the technology acceptance model (TAM) in research frameworks is affirmed by our findings. Through a rigorous thematic analysis, our study identified five overarching themes, each encompassing a diverse range of sub-themes. These themes encompass 1) technological factors, 2) individual factors, 3) organizational factors, 4) environmental factors, and 5) security factors. This categorization provides a structured framework for understanding the multifaceted nature of CBEL adoption determinants. Our study serves as a compass, guiding future research endeavours in this domain. It underscores the imperative for further investigations utilizing diverse theoretical frameworks, contextual settings, research methodologies, and variables. This call for diversity and expansion in research efforts reflects the dynamic nature of CBEL and the evolving landscape of e-learning technologies.

• 공업화학
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• 제28권4호
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• pp.448-453
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• 2017

테일러 반응기에서 일어나는 유동의 변화를 전산유체역학을 이용하여 3차원 유동해석을 수행하였다. 테일러 유동은 레이놀즈 수의 증가에 따라 5개의 영역(순환 쿠에트 유동(CCF), 테일러 와류 유동(TVF), 물결 와류 유동(WVF), 변조 물결 와류 유동(MWVF), 난류 테일러 와류 유동(TTVF))으로 나뉘어지며, 각각의 영역에서의 유동 특성을 알아보았다. 각각의 영역에서 와류의 형상, 개수, 길이 등에 차이를 나타나며 바이패스 흐름에도 영향을 줌을 확인하였다. 그 결과 TVF, WVF, MWVF, TTVF 영역에서 테일러 와류가 발생하였다. 테일러 와류의 개수는 TVF 영역에서 가장 많으며 TTVF 영역에서 가장 적게 관찰되었다. 수치해석모델의 검증을 위하여 실험결과와 비교하였고, 실험결과 대비 해석결과가 잘 일치함을 나타내었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3817-3825
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• 2015

Background: The human protein methyl-transferase DOT1L catalyzes the methylation of histone H3 on lysine 79 (H3K79) at homeobox genes and is also involved in a number of significant processes ranging from gene expression to DNA-damage response and cell cycle progression. Inhibition of DOT1L activity by shRNA or small-molecule inhibitors has been established to prevent proliferation of various MLL-rearranged leukemia cells in vitro, establishing DOT1L an attractive therapeutic target for mixed lineage leukemia (MLL). Most of the drugs currently in use for the MLL treatment are reported to have low efficacy, hence this study focused on various natural compounds which exhibit minimal toxic effects and high efficacy for the target receptor. Materials and Methods: Structures of human protein methyl-transferase DOT1L and natural compound databases were downloaded from various sources. Virtual screening, molecular docking, dynamics simulation and drug likeness studies were performed for those natural compounds to evaluate and analyze their anti-cancer activity. Results: The top five screened compounds possessing good binding affinity were identified as potential high affinity inhibitors against DOT1L's active site. The top ranking molecule amongst the screened ligands had a Glide g-score of -10.940 kcal/mol and Glide e-model score of -86.011 with 5 hydrogen bonds and 12 hydrophobic contacts. This ligand's behaviour also showed consistency during the simulation of protein-ligand complex for 20000 ps, which is indicative of its stability in the receptor pocket. Conclusions: The ligand obtained out of this screening study can be considered as a potential inhibitor for DOT1L and further can be treated as a lead for the drug designing pipeline.

• 천문학회지
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• 제49권5호
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• pp.193-198
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• 2016

Early-type galaxies (ETGs) are supposed to follow the virial relation $M=k_e{\sigma}^2R_e/G$, with M being the mass, σ_* being the stellar velocity dispersion, R_e being the effective radius, G being Newton's constant, and k_e being the virial factor, a geometry factor of order unity. Applying this relation to (a) the ATLAS^3D sample of Cappellari et al. (2013) and (b) the sample of Saglia et al. (2016) gives ensemble-averaged factors 〈k_e〉 = 5.15 ± 0.09 and 〈k_e〉 = 4.01 ± 0.18, respectively, with the difference arising from different definitions of effective velocity dispersions. The two datasets reveal a statistically significant tilt of the empirical relation relative to the theoretical virial relation such that $M{\propto}({\sigma}^2_*R_e)^{0.92}$. This tilt disappears when replacing R_e with the semi-major axis of the projected half-light ellipse, a. All best-fit scaling relations show zero intrinsic scatter, implying that the mass plane of ETGs is fully determined by the virial relation. Whenever a comparison is possible, my results are consistent with, and confirm, the results by Cappellari et al. (2013). The difference between the relations using either a or R_e arises from a known lack of highly elliptical high-mass galaxies; this leads to a scaling (1 - ϵ ) ∝ M^0.12, with ϵ being the ellipticity and $R_e=a\sqrt[]{1-{\epsilon}}$. Accordingly, a, not R_e, is the correct proxy for the scale radius of ETGs. By geometry, this implies that early-type galaxies are axisymmetric and oblate in general, in agreement with published results from modeling based on kinematics and light distributions.

• 한국세라믹학회지
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• 제38권8호
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• pp.698-704
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• 2001

Doped ceria의 전기전도도는 도핑 원소의 종류와 양에 큰 의존성을 가지고 특정 조성에서 최대 전도도 값을 가지며 높은 dopant 농도에서는 전기전도도는 감소한다. 이런 현상은 dopant와 산소 빈자리 사이의 회합 형성과 관련이 있다고 알려져 있다. 그러나 Gd 이온이 도핑된 ceria의 경우 주된 회합종이 (2G $d_{Ce}$ $V_{o}$ )인지 (G $e_{Ce}$ $V_{o}$ ) 인지는 명확하게 알려져 있지 않다. 본 연구에서는 회합분포가 전기전도도에 미치는 영향을 연구하기 위해 결함의 회합종과 분포가 다른 3가지 경우에 대해서 시뮬레이션을 행하였다. 분자동력학법을 이용하여 다양한 온도와 다른 회합분포의 경우에 대해 산소 확산계수가 계산되어졌으며, 계산된 산소 확산계수는 실험적으로 결정된 bulk 전도도로부터 얻어진 산소 확산계수와 비교되어졌다. 그 결과 (2G $d_{Ce}$ $V_{o}$ )와 (G $e_{Ce}$ $V_{o}$ ) 회합이 공존하며 이들이 통계학적으로 이항 분포를 가지는 경우가 실험적으로 보고된 값과 가장 일치하는 결과를 얻을 수 있었다.

• 한국수소및신에너지학회논문집
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• 제11권3호
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• pp.127-136
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• 2000

Molecular dynamics simulations have been carried out to investigate the scattering and penetration properties of hydrogen ions with the normal incident angle to Ni (100) surface. The initial kinetic energies of hydrogen ions range from 100 to 1,600 eV. The simulation results are used to assess the applicabilities of theoretical predictions based on the binary collision approximation, and, in the high kinetic regime, theoretical results for scattering energies were shown to he a good agreement with molecular simulations. The angle dependencies on both scattering and penetration distributions were found in the longitudinal direction, but not in the azimuthal direction except for the high kinetic energy of 1,600 eV.

• 한국수소및신에너지학회논문집
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• 제12권3호
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• pp.191-199
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• 2001

In this paper molecular dynamics simulations have been carried out to investigate energy and momentum transfer of hydrogen ions impacted on the Ni (100) surface with $45^{\circ}$ and $90^{\circ}$ incident angles. The initial kinetic energies of the hydrogen ion were ranged from 100 eV to 1,600 eV to study the layer-by-layer energy variation as a dependence of incident energies and angles. At low incident energies, the scattering energy transfer is dominated by the normal motion of surface layers due to thermal vibrations and multiple collision effects. For higher incident energies, the scattering energy transfer in a normal direction is greater than that in a parallel direction. In the case of penetration, the amount of transferred energies do not affect much on Ni layers at low incident energy. It was found channeling effects through Ni layers with increasing incident energies.

• Environmental Engineering Research
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• 제17권2호
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• pp.69-75
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• 2012

Composting of water hyacinth, mixed with cattle manure, rice husk and sawdust in four different proportions, was performed in a pilot scale rotary drum composter. The physico-chemical characteristics, i.e., temperature, moisture content, pH, electrical conductivity, total organic matter (OM), nitrogen dynamics and nutrients were evaluated during the 20 days composting process. The stabilities of the composts were also investigated with respirometric analysis, i.e., $CO_2$ evolution rates and oxygen uptake rate (OUR). Among all trials, trial 1 (6 water hyacinth, 3 cattle manure, 1 rice husk) indicated the best composting mix, as shown by the highest temperature profile and OM loss, and lowest $CO_2$ evolution rate and OUR.