• Bulletin of the Korean Chemical Society
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• v.27 no.9
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• pp.1401-1404
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• 2006

Eight structurally different acetylcholinesterase reactivators derived from currently commercially available oximes were tested for their potency to reactivate acetylcholinesterase inhibited by pesticide paraoxon (P) and DFP (D). Housefly AChE (F) and bovine red blood cell AChE (B) were used as the source of the cholinesterases. Ellman's method was taken to examine cholinesterases activity. The results show that four AChE reactivators are potent AChE reactivators, able to reach reactivation potency of more than 30% in all cases - PF, PB, DF and DB. Their reactivation potency was comparable with that of pralidoxime and even higher compared with that of HI-6, standard AChE reactivators currently available on the market.

• The Journal of Korean Society for School & Community Health Education
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• v.23 no.2
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• pp.65-76
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• 2022

Objectives: The purpose of this study is to investigate the factors that affect the smoking type among those who have used regular cigarettes, liquid or cigarette-type e-cigarettes. Methods: The subjects of analysis were 6,081 people who had smoked regular cigarettes or e-cigarettes. For data analysis, SPSS ver.25.0 statistical package program was used. Multinomial logistic regression analysis was performed to find out the factors affecting smoking type. Results: Factors affecting the experience of using e-cigarettes compared to regular cigarette smoking are gender and class. Academic performance, living with family members, drinking experience, and secondhand smoke in school. The factors influencing dual use compared to regular cigarette smoking were gender, class, academic performance, economic status, living with family, drinking experience, and experience of secondhand smoke in school. Smoking cessation attempts had an effect on dual use compared to regular cigarette smoking. Conclusion: Smoking cessation experience had a greater effect on e-cigarette use than regular cigarette smoking.

• Journal of Food Hygiene and Safety
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• v.24 no.4
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• pp.307-311
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• 2009

The objectives of this study were to compare the biochemical profiles with biogroups for the identification of Cronobacter spp. (formally known as Enterobacter sakazakii) isolates using biochemical identification kits. A total of 38 Cronobacter spp. contained 5 clinical, 31 food, and 2 environmental isolates were used. All isolates were identified as Cronobacter spp. with the Vitek II system and ID 32E kit. The API 20E kit identified all isolates as Cronobacter spp. but the percentage identification was 51.1% for 16 of 38 isolates. These strains were contained to Biogroup 2, 9, 10, and 11. The utilization of inositol is a factor determining the percentage identification of Cronobacter spp. with the API 20E kit.

• Journal of Information Processing Systems
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• v.15 no.2
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• pp.239-250
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• 2019

An individual's health data is very sensitive and private. Such data are usually stored on a private or community owned cloud, where access is not restricted to the owners of that cloud. Anyone within the cloud can access this data. This data may not be read only and multiple parties can make to it. Thus, any unauthorized modification of health-related data will lead to incorrect diagnosis and mistreatment. However, we cannot restrict semipublic access to this data. Existing security mechanisms in e-health systems are competent in dealing with the issues associated with these systems but only up to a certain extent. The indigenous technologies need to be complemented with current and future technologies. We have put forward a method to complement such technologies by incorporating the concept of blockchain to ensure the integrity of data as well as its provenance.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.10
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• pp.979-985
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• 2010

This study was performed to detect enterococci strain as an indicator of faecal contamination, to identify of 16S rDNA sequence and vancomycin resistance by MIC (Minimum Inhibitory Concentration) test from drinking spring-water samples in Seoul. The detection frequency of enterococci was 42 (19.8%) among 212 samples, and its concentration was ranged from 0 to 110 CFU/100 mL. These results were confirmed the possibility as an indicator microorganisms that similar to the frequency of E. coli detection (t test p-value 0.268, significant level 0.05). Isolated 56 enterococci samples were identified by 16S rDNA sequence data and their NCBI BLAST searching. They were identified to Enterococcus faecalis of 24 samples, E. faecium (10), E. casseliflavus (10), E. gallinarum (3), E. hirae (2), E. durans (2), E. sanguinicola (1). E. faecalis was dominant species that clinical case report of a domestic was similar. Vancomycin resistant enterococci (VRE) of 53 samples showed that vanB and vanC1/C2 type with 2 and 12 case, respectively. These results indicated that the drinking spring-water quarantined to fecal pollution for block out outbreak of gastrointestinal symptom with using such as disinfection process.

• Journal of the Korea Convergence Society
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• v.10 no.8
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• pp.171-179
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• 2019

This study was to develop the health education program model of young children based on e-book using QR code to prevent and manage fine dust. We developed program to prevent and manage fine dust for young children' health through in-depth discussions with 2 young children's health experts and 3 young children education experts, and developed the e-book using QR code. The program model for fine dust's prevention education based on e-book using QR code was verified for suitability as a field adaptation and teaching medium for 5-year old. The results of this study are as follows: First, the program model for fine dust's prevention education based on e-book using QR code was developed through 3 stages of appreciation activity-central activity-finishing activity. Second, the e-book using QR code is a useful teaching medium applicable to fine dust's prevention education program. In conclusion, the e-book-based fine dust's prevention education program using QR code will be used as an appropriate education method for fine dust's prevention and health management activities in the field of education for young children.

• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.325-334
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• 2023

Edema disease (ED) in pigs is enterotoxemia caused by Shiga toxin type 2e (Stx2e)-producing Escherichia coli (STEC) and frequently occurs in young piglets. Therefore, ED causes enormous economic losses in pig farms. In this study, a modified Stx2e (mStx2e) antigen was expressed and purified using commercial E. coli expression system. Monoclonal antibody was serviced by Ynto Ab Inc., using Phage Display Technique. Anti-Stx2e antibodies in piglets were measured by indirect ELISA using mStx2e antigens. Naive Stx2e in piglets were detected by Sandwich ELISA using Stx2e-monoclonal antibodies and commercial Stx2e-polyclonal antibodies. Among 3,480 piglets, anti-Stx2e antibodies were observed in 2,573 piglets. The 49.4% among 830 piglet serum samples possessed 0.625 ㎍/mL or more of Stx2e proteins. The 18.3% of 830 sera had 0.313 ㎍/mL of Stx2e proteins. The 32.3% of 830 samples held 0.156 ㎍/mL or less of Stx2e proteins. These results show that indirect ELISA using mStx2e antigen and Sandwich ELISA using Stx2e-monoclonal and polyclonal antibodies can be useful to detect ED in piglets.

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.130.1-130.1
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• 2000

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2619-2627
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• 2015

There are several studies that relate oxidative damage as possible mechanism for many cancers. Many studies have also shown that anti-oxidants like selenium and vitamin E decrease the risk for prostate cancer. The main objective of the Selenium and Vitamin E Cancer Prevention Trial (SELECT) study was to look for the benefits of selenium and vitamin E supplementation on prostate cancer. The study had a large sample size, stringent experimental conditions, very long duration, standardized laboratories for biochemical analyses and other factors that contribute to high external validity. The SELECT study failed to show any significant risk reduction for prostate cancers ascribable to selenium and vitamin E supplementations. Because of these conflicting results, many researchers argue about the methods used, supplementations administered (selenium and vitamin E) and indicators used for assessing levels of supplementations. We reviewed many epidemiological studies, clinical trials, and pre-clinical studies. With corroborative evidences we justify that SELECT study has a sound methodology and rationale. In lieu of the contrary results of the select study, researchers should focus on the probable mechanisms for these contrary findings and continue their search for newer and effective agents for prevention of prostate cancer.

• Journal of Preventive Medicine and Public Health
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• v.36 no.1
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• pp.77-84
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• 2003

Objectives : Two related cases of Hemolytic-Uremic Syndrome (HUS) were reported to the Korea National Institute of Health in May, 2001. Shiga toxin 2 genes were detected in both stool samples. We suspected an enterohemorrhagic Escherichia coli (EHEC) infection as the cause of the HUS, and conducted an investigation to find the source of the infection and its route of transmission. Methods : We peformed case investigations on these two related HUS cases, and obtained interviews and rectal swabs form the family members and other close contacts. Additionally, we peformed rectal swabs on the cattle raised by the household of the index patient. Results : We found a 20 month old index patient and a 6 year-old cousin had developed HUS, where there had been a 2 day history of contact with the index, and bacteriological examinations for these two patients revealed, indistinguishably, the same E. coli O171. The grandmother of the index patient was found to be asymptomatic, but E. coli O26 was isolated. We also found a probable case in the mother of the cousin. She reported a history of contact with the index, and developed bloody diarrhea of 3 days duration. The test results for the cattle revealed E. coli O26 in one cow, and E. coli O26 and O55 in another. E. coli O26, which was isolated in both cows and the grandmother of the index, were indistinguishably the same. Conclusions : We found that the E. coli O26 in the grandmother had originated from the cows, and that the E. coli O171 found in the index patient had been transmitted to the cousin through person-to-person contact.