• Development and Reproduction
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• v.6 no.2
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• pp.105-110
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• 2002

Numerous hormones are involved in the regulation of reproduction. Among them, estrogen and progesterone are the most important ovarian steroid hormones regulating female fertility. On the other hand, diverse stressors impede female receptivity and fertility. Since norepinephrine(NE) and epinephrine(E) are released from the adrenal during stress, it might play a role in stress-induced disruptions of fEmale reproductive parameters. The present study was performed to analyze the changes in adrenal catecholaminergic activities in cycling rats. The tissue content and secretion level of catecholamines were determined by high performance liquid chromatography coupled with electrochemical detector(HPLC-ECD). Adrenomedullary content of norepinephrine(NE) was increased on proestrus stage (59.47 $\pm$ 6.86 ug/gland), peaked on diestrus I stage(65.22 $\pm$ 5.99 ug/gland), and was nadir on diestrus II stage(41.63 $\pm$ 1.33 ug/gland). The highest E content was observed on proestrus stage(361.86 $\pm$ 15.58 ug/gland) while the lowest level was on diestrus II stage(285.58 $\pm$ 12.25 ug/gland). In addition to these observations, a significant reduction of the NE : E ratio was observed (1 : 4.81 on diestrus I vs 1 : 6.13～7.02 on other stages). In vitro secretion of adrenal NE and E was increased on proestrus stage, peaked on estrus stage, and decreased on diestrus II stage. Interestingly, the NE : E ratio in conditioned media was significantly increased on estrus stage (1 : 3.32 vs 1 : 2.34～2.65 on other stages. The biosynthesis of NE and E is mediated by tyrosine hydroxylase(TH) and phenylethanolamine-N-methyltransferase(PNMT) which acts conversion of tyrosine into DOPA and NE into E, respectively. These finding demonstrated that sex steroids, during setrous cycle, seem to be able to modify the adrenal catecholamines biosynthesis and secretion with stage-specific manner by modulation of the enzyme activities.

• Proceedings of the Korean Society of Organic Agriculture Conference
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• 2004.12a
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• pp.1-16
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• 2004

This study was conducted to investigate effects of different ratios of sawdust to poultry manure as an earthworm feed on the change of physico-chemical characteristics and earthworm viability during composting, and further to provide the basic information for an efficient vermicomposting using the manure of livestock. Experimental earthworm used in this study was Eisenia foetida and the ratio of sawdust and poultry was determined to 100:0(A), 80:20(B), 70:30(C), 60:40(D) and 50:50(E) on the basis of volume. The results are summarized as follows. Earthworm appeared after 6 wk of aging period, and it was possible for the earthworm to survive in treatments of C. D and E including 30 $^{\sim}$ 50% of sawdust. C/N ratio was significantly higher (P<0.05) in treatments of sawdust mixture (B, C, D, and E) than poultry manure alone (A treatment).Appropriate C/N ratio for earthworm survival was the range of 16.9 to20.7. During period of aging, pH value and electrolyticconductivity (EC) were the highest in the treatment of poultry manure alone. However, as the inclusion of sawdust was increased, pH showed decreasing tendency. Appropriate pH and EC for earthworm survival were 7.69 to 7.79, and 2.77 to 2.87mS/cm, respectively. The results from this study indicated that the mixing of poultry manure with sawdust more improved physico-chemical environment for earthworm growth in comparison with poultry manure alone, and sawdust showed the sufficient possibilityas a bulking agent for an efficient vermicomposting of poultry manure.

• Transactions of Materials Processing
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• v.18 no.5
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• pp.410-415
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• 2009

Experimental and numerical studies were performed to examine the effect of material temperature and reduction ratio on friction coefficient during hot flat rolling. We carried out a single pass pilot hot flat rolling test at the temperatures range of $900{\sim}1200^{\circ}C$ and measured the spread of deformed material while reduction ratio varied from 20% to 40%. Materials used in this study were a high carbon steel and two alloy steels. The dimension of specimen used in hot rolling experiment was $50mm{\times}50mm{\times}300mm$. We performed a series of finite element simulation of the hot rolling process to compute the friction coefficient change in terms of steel grade and reduction ratio. Results showed that temperature dependency of friction coefficient is not noteworthy but the effect of reduction ratio on friction coefficient is quite large. For high carbon steel, friction coefficient at reduction ratio of 30% is lower than that at that of 20%. Meanwhile friction coefficient at reduction ratio of 40% was one and half times large compared with that at that of 20%. The effect of steel grade on friction coefficient was significant when reduction ration was large, e.g., 40%.

• Journal of Gastric Cancer
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• v.15 no.4
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• pp.238-245
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• 2015

Purpose: This study aimed to identify time-dependent prognostic factors and demonstrate the time-dependent effects of important prognostic factors in patients with advanced gastric cancer (AGC). Materials and Methods: We retrospectively evaluated 3,653 patients with AGC who underwent curative standard gastrectomy between 1991 and 2005 at the Korea Cancer Center Hospital. Multivariate survival analysis with Cox proportional hazards regression was used in the analysis. A non-proportionality test based on the Schoenfeld residuals (also known as partial residuals) was performed, and scaled Schoenfeld residuals were plotted over time for each covariate. Results: The multivariate analysis revealed that sex, depth of invasion, metastatic lymph node (LN) ratio, tumor size, and chemotherapy were time-dependent covariates violating the proportional hazards assumption. The prognostic effects (i.e., log of hazard ratio [LHR]) of the time-dependent covariates changed over time during follow-up, and the effects generally diminished with low slope (e.g., depth of invasion and tumor size), with gentle slope (e.g., metastatic LN ratio), or with steep slope (e.g., chemotherapy). Meanwhile, the LHR functions of some covariates (e.g., sex) crossed the zero reference line from positive (i.e., bad prognosis) to negative (i.e., good prognosis). Conclusions: The time-dependent effects of the prognostic factors of AGC are clearly demonstrated in this study. We can suggest that time-dependent effects are not an uncommon phenomenon among prognostic factors of AGC.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.6
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• pp.999-1012
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• 2017

Theoretical, empirical and numerical methods are used to evaluate the rock load due to tunnelling. Theoretical and empirical methods do not consider ground conditions, tunnel shape, and construction conditions. However, through numerical analysis, it is possible to analyze the displacement and stresses around tunnel due to its excavation, and evaluate the rock load considering ground and construction conditions. The stress transfer ratio(e) which is defined as a ratio of the difference between the major and minor principal stresses to major principal stress is used in order to understand the stress transfer effect around the tunnel excavation using numerical analysis results. The loosend area around tunnel periphery was found based on this approach. The difference of rock load from stress transfer effect was found according to the ground grade. From comparison, rock load obtained from stress transfer effect (e = 10%) were somewhat larger than the results obtained from the critical strain method, but smaller than those obtained from theoretical and empirical methods. The stress transfer effect approach considers the ground condition, tunnel shape; therefore, it can be applied to evaluate the rock load in concrete lining design.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.10
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• pp.1411-1416
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• 2014

Gender selection is important in livestock industries; for example, female calves are required in the dairy industry. Sex-sorted semen is commonly used for the production of calves of the desired gender. However, assessment of the sex ratio of the sorted semen is tedious and expensive. In this study, a rapid, cost effective and reliable method for determining the sex ratio was developed using a multiplex real-time polymerase chain reaction (PCR) assay. In this assay, the X and Y chromosome-specific markers, i.e., bovine proteolipid protein (PLP) gene and sex-determining region Y (SRY) were simultaneously quantified in a single tube. The multiplex real-time PCR assay was shown to have high amplification efficiencies (97% to 99%) comparable to the separated-tube simplex real-time PCR assay. The results obtained from both assays were not significantly different (p>0.05). The multiplex assay was validated using reference DNA of known X ratio (10%, 50%, and 90%) as templates. The measured %X in semen samples were the same within 95% confidence intervals as the expected values, i.e., >90% in X-sorted semen, <10% in Y-sorted semen and close to 50% in the unsorted semen. The multiplex real-time PCR assay as shown in this study can thus be used to assess purity of sex-sorted semen.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.6 s.177
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• pp.1557-1564
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• 2000

When the half infinite crack in the orthotropic material strip with a large anisotropic ratio(E11>>E22) propagates with constant velocity, dynamic stress component $\sigma$y occurre d along the $\chi$ axis is derived by using the Fourier transformation and Wiener-Hopf technique, and the dynamic stress intensity factor is derived. The dynamic stress intensity factor depends on a crack velocity, mechanical properties and specimen hight. The normalized dynamic stress intensity factors approach the maximum values when normalized time(=Cs/a) is about 2. They have the constant values when the normalized time is greater than or equal to about 2, and decrease with increasing a/h(h: specimen hight, a: crack length) and the normalized crack propagation velocity( = c/Cs, Cs: shear wave velocity, c: crack propagation velocity).

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.7
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• pp.946-951
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• 2011

The study was conducted to evaluate enzose (corn dextrose), a corn milling byproduct, as substitute for corn grain as energy in growing lambs. Five iso-caloric and iso-nitrogenous diets were formulated. The control diet (E0) had no enzose whereas enzose replaced 20, 40, 60 and 80% corn grain in E20, E40, E60 and E80 diets on the basis of energy supply, respectively. Fifty growing lambs were divided into 5 groups, 10 animals in each, in a randomized complete block design. Nutrients (dry matter, crude protein, neutral detergent fiber and acid detergent fibre) intake and digestibilities increased with gradual replacement of corn grain by enzose. Lambs fed E80 diet also retained higher nitrogen (N) than those fed E0 diet. Plasma glucose, $T_3$ and $T_4$ increased while urea N decreased in lambs receiving higher enzose content. Maximum weight gain was recorded in lambs fed diets containing maximum concentration of E as a replacement for corn grains. A better feed conversion ratio was recorded in lambs fed E80 compared with those fed E0 diet. The study suggests that enzose can be used as an economical feed ingredient to replace corn grain upto 80%, without any adverse effects on growth performance of growing lambs.

• Journal of Korea Society of Industrial Information Systems
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• v.7 no.5
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• pp.183-189
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• 2002

In this paper, we propose an algorithm to extract the E-mail address in calling card images. Firstly, text regions are separated from background. in the image. To do this, the properties of e-mail addresses and the texture features in the image is used. And then, each text region is explored to find the candidates of e-mail region. Finally, each candidate is divided into characters to find at-symbol(@), that is, e-mail region. The experimental results show hit-ratio over 93.3％ for the various kind of calling cards containing different fonts, background images, caricatures.

• KSBB Journal
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• v.23 no.6
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• pp.509-512
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• 2008

The hydrolysis reaction of soybean oil was conducted experimentally by various source enzymes. The analytical result of hydrolysate of soybean oil showed that the compositions were linoleic acid, olic acid, palmitic acid, and stearic acid in order. The enzymes CR-E and CC-E from Candida rufosa and Candida cylindracea had two hold or more hydrolysis conversions than those of Lipase 16, Novozyme 871, and Lipolase-100L under the same conditions. Therefore CR-E and CC-E were selected for further experiments. These two enzymes had similar ranges of optimun conditions as follows: pH 3-6, $35-45^{\circ}C$, and water to soybean oil ratio of 3.3 or above. They finally got conversions 95% above.