• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1998년도 춘계학술발표회논문집(2)
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• pp.336-343
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• 1998

An iteration method has been developed for determining crack growth and fracture resistance cure (J-R curve) from the load versus load-line displacement record only. In this method, the hardening curve, the load versus displacement curve at a given crack length, is assumed to be a power-law function, where the exponent varies with the crack length. The exponent is determined by an iterative calculation method with the assumption that the exponent varies linearly with the load-line displacement. The proposed method was applied to the static J-R tests using compact tension(CT) specimens, a three-point bend (TPB) specimen, and a cracked round bar (CRB) specimen as well as it was applied to the quasi-dynamic J-R tests using CT specimens. The J-R curves determined by the proposed method were compared with those obtained by the conventional testing methodologies. The results showed that the J-R curves could be determined directly by the proposed iteration method with sufficient accuracy in the specimens from SA508, SA533, and SA516 pressure vessel steels and SA312 Type 347 stainless steel.

• Nuclear Engineering and Technology
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• 제38권4호
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• pp.327-342
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• 2006

Radiation therapy is an important part of cancer treatment in which cancer patients are treated using high-energy radiation such as x-rays, gamma rays, electrons, protons, and neutrons. Currently, about half of all cancer patients receive radiation treatment during their whole cancer care process. The goal of radiation therapy is to deliver the necessary radiation dose to cancer cells while minimizing dose to surrounding normal tissues. Success of radiation therapy highly relies on how accurately 1) identifies the target and 2) aim radiation beam to the target. Both tasks are strongly dependent of imaging technology and many imaging modalities have been applied for radiation therapy such as CT (Computed Tomography), MRI (Magnetic Resonant Image), and PET (Positron Emission Tomogaphy). Recently, many researchers have given significant amount of effort to develop and improve imaging techniques for radiation therapy to enhance the overall quality of patient care. For example, advances in medical imaging technology have initiated the development of the state of the art radiation therapy techniques such as intensity modulated radiation therapy (IMRT), gated radiation therapy, tomotherapy, and image guided radiation therapy (IGRT). Capability of determining the local tumor volume and location of the tumor has been significantly improved by applying single or multi-modality imaging fur static or dynamic target. The use of multi-modality imaging provides a more reliable tumor volume, eventually leading to a better definitive local control. Image registration technique is essential to fuse two different image modalities and has been In significant improvement. Imaging equipments and their common applications that are in active use and/or under development in radiation therapy are reviewed.

• 통합자연과학논문집
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• 제1권2호
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• pp.79-83
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• 2008

As a new standard for performance measurement, NEMA NU2-2001 was presented recently. In this study, I investigated the spatial resolution, sensitivity, scatter fraction, and noise equivalent count ratio (NECR) in order to know the information of physical characteristics and system performance of GE discovery ST using this new standard. Bismuth germinate crystals ($6{\times}6$ array, $6.3mm{\times}6.3mm{\times}30mm$) were used in discovery ST (energy window:375-650 keV, coincidence window:11.7 nsec). To measure the sensitivity, five aluminum sleeves (Data Spectrum Corp., Chapel Hill, NC., USA, thickness:1.25 mm)-NEMA sensitivity phantom- filled with F-18 solution were used. Successive measurements in 2D and 3D acquisition mode were made with a line source at the center of transaxial field of view and 10 cm off from the center until the count was over 500,000. Spatial resolution was estimated using a point source (F-18, 0.1 mCi) at different locations in the FOV. Scatter fraction and NECR was tested using a NEMA scatter phantom. Dynamic data were acquired for 7 half-lives using F-18 solution. And true to background ratio was averaged at last three frames when the random rate was as small as ignorable for the calculation of scatter fraction. We anticipate this overall evaluated results could be used for the quality assurance and optimized image acquisition for clinical research.

• Investigative Magnetic Resonance Imaging
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• 제20권4호
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• pp.259-263
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• 2016

Primary diffuse large B-cell lymphoma of the seminal vesicle is an extremely rare disorder, with only two cases reported in the English literature. Here, we present imaging findings of a case of primary diffuse large B-cell lymphoma of the seminal vesicle. On transrectal ultrasonography, the mass presented as a 3.0-cm-sized heterogeneous, hypoechoic lesion in the right seminal vesicle. Computed tomography (CT) revealed a mass with rim-like enhancement in the right seminal vesicle. On magnetic resonance imaging (MRI), the tumor showed iso-signal intensity on T1-weighted images and heterogeneously intermediate-high signal intensity on T2-weighted images. The tumor showed rim-like and progressive enhancement with non-enhancing portion on dynamic scanning. Diffusion restriction was observed in the mass. On fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging, a high standardized uptake value (maxSUV, 23.5) by the tumor was noted exclusively in the right seminal vesicle.

• 대한기계학회논문집B
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• 제37권10호
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• pp.953-959
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• 2013

본 연구에서는 가상 생체외 사체실험을 수행할 수 있는 경추 다관절 동역학 모델을 개발하였다. 평균크기 한국인 의료영상과 관절 및 연부조직의 물성 정보를 기반으로 하여 경추 동역학 모델을 개발하였다. 개발된 모델의 검증을 위하여 경추 단분절 및 다분절 모멘트-각도 관계, 인대 하중 및 후관절 접촉력 등을 문헌의 사체실험 결과와 비교한 결과 매우 유사한 경향을 확인하였다. 본 연구에서 개발된 경추 동역학 모델은 앞으로 경추 사체실험 연구 뿐만 아니라 자동차 충돌시 경추 상해 분석 등의 다양한 경추 생체역학 연구 연구에 활용될 수 있을 것이다.

• The Korean Journal of Ecology
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• 제28권4호
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• pp.181-188
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• 2005

Methods used to study carbon sequestration by soil aggregates have often excluded the concentric spatial variability and other dynamic processes that contribute to resource accessibility and solute transport within aggregates. We investigated the spatial gradients of carbon (C) and nitrogen (N) from the exterior to interior layers within macroaggregates, $6.3\sim9.5$ mm, sampled from conventional tillage (CT) and no tillage (NT) sites of a Hoytville silt clay loam. Spatial gradients in C accumulation within macroaggregates were related to the differences in C dynamics by determining the sizes and the turnover rates of fast C and slow C pools in the concentric layers of aggregates. Aggregate exteriors contained more labile C and were characterized by greater C mineralization rates than their interiors in both management systems. In contrast, C in the interior layers of aggregates was more resistant in both systems. These results indicated the spatial differentiation of C dynamics within macroaggregates, i.e., exterior layers as a reactive site and interior layers as a protective site. Greater total C distribution in the exterior layers of NT aggregates indicated more influx of C from the macropores in interaggregate space than C. mineralization (net gain of C), whereas lower C distribution within the exterior layers of CT aggregates indicated net loss of C by greater C mineralization than C influx. We found total C increased approximately 1.6-fold by the conversion of CT soils to NT management systems for a period of 36 years. Differences in total accumulation and the spatial distribution of C within aggregates affected by management were attributed to the differences in aggregate stability and pore networks controlling the spatial heterogeneities of resource availability and microbial activity within aggregates.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.468-470
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• 2002

We have designed X-ray detection system and multi-channel data acquisition system for Spiral CT application. X-ray detection system consists of scintillator and photodiode. Scintillator converts X-ray into visible light. Photodiode converts visible light into electrical signal. The multi-channel data acquisition system consists of analog, digital, master and backplane board. Analog board detects electrical signal and amplifies signal by 140dB. Digital board consists of MUX(Multiplex) which routes multi-channel analog signal to preamplifier, and ADC(Analog to Digital Converter) which converts analog signal into digital signal. Master board supplies the synchronized clock and transmits the digital data to image reconstructor. Backplane provides electrical power, analog output and clock signal. The system converts the projected X-ray signal over the detector array with large gain, samples the data in each channel sequentially, and the sampled data are transmitted to host computer in a given time frame. To meet the timing limitation, this system is very flexible since it is implemented by FPGA(Field Programmable Gate Array). This system must have a high-speed operation with low noise and high SNR(signal to noise ratio), wide dynamic range to get a high resolution image.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.333-339
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• 2009

Objective : Few studies on the clinical spectrum of automated pressure-controlled discography (APCD)-defined positive discs have been reported to date. Thus, the present study was undertaken to analyze clinical parameters critical for diagnosis of discogenic pain and to correlate imaging findings with intradiscal pressures and pain responses in patients with APCD-positive discs. Methods : Twenty-three patients who showed APCD-positive discs were selected for analysis. CT discogram findings and the degrees of nuclear degeneration seen on MRI were analyzed in comparison to changes of intradiscal pressure that provoked pain responses; and clinical pain patterns and dynamic factors were evaluated in relation to pain provocation. Results : Low back pain (LBP), usually centralized, with diffuse leg pain was the most frequently reported pattern of pain in these patients. Overall, LBP was most commonly induced by sitting posture, however, standing was highly correlated with L5/S1 disc lesions (p<0.01). MRI abnormalities were statistically correlated with grading of CT discogram results (p<005); with most pain response observed in CT discogram Grades 3 and 4. Pain-provoking pressure was not statistically correlated with MRI grading. However, it was higher in Grade 3 than Grade 4. Conclusion : APCD-positive discs were demonstrated in patients reporting centralized low back pain with diffuse leg pain, aggravated by sitting and standing. MRI was helpful to assess the degree of nuclear degeneration, yet it could not guarantee exact localization of the painful discs. APCD was considered to be more useful than conventional discography for diagnosis of discogenic pain.

• Transactions on Electrical and Electronic Materials
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• 제13권6호
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• pp.273-277
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• 2012

The vacuum drying process for drying of paper in current transformers was modeled with an aim to develop an understanding of the drying mechanism involved and also to predict the water collection rates. A molecular as well as macroscopic approach was adopted for the prediction of drying rate. Ficks law of diffusion was adopted for the prediction of drying rates at macroscopic levels. A steady state and dynamic mass transfer simulation was performed. The bulk diffusion coefficient was calculated using weight loss experiments. The accuracy of the solution was a strong function of the relation developed to determine the equilibrium moisture content. The actually observed diffusion constant was also important to predict the plant water removal rate. Thermo gravimetric studies helped in calculating the diffusion constant. In addition, simulation studies revealed the formation of perpetual moisture traps (loops) inside the CT. These loops can only be broken by changing the temperature or pressure of the system. The change in temperature or pressure changes the kinetic or potential energy of the effusing vapor resulting in breaking of the loop. The cycle was developed based on this mechanism. Additionally, simulation studies also revealed that the actual mechanism of moisture diffusion in CT's is by surface jumps initiated by surface diffusion balanced against the surrounding pressure. Every subsequent step in the cycle was to break such loops. The effect of change in drying time on the electrical properties of the insulation was also assessed. The measurement of capacitance at the rated voltage and one third of the rated voltage demonstrated that the capacitance change is within the acceptance limit. Hence, the new cycle does not affect the electrical performance of the CT.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1066-1076
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• 2018

Objective: The reliability of size measurements of liver metastases from neuroendocrine tumors (NETs) on contrast-enhanced computed tomography (CT) phases made by different readers may be hampered due to transient, variable rim enhancement in arterial phase (AP) or portal venous phase (PVP) images. We aimed to assess the reliability of tumor size measurements in pre- and post-contrast scans. Materials and Methods: The study coordinator selected target lesions according to Response Evaluation Criteria in Solid Tumors 1.1 guidelines in 44 consecutive patients with pathologically confirmed NET liver metastases. Two blinded readers measured the longest diameters of target lesions on pre-contrast, AP, and PVP images twice with a 4-week interval. Inter- and intra-observer agreements were evaluated using Bland-Altman plots and 95% limit of agreement (LOA) calculations. Results: Of the 79 target lesions (approximate mean size of 3 cm), 45 showed rim enhancement. Inter-observer agreement assessed based on LOA was highest in pre-contrast CT images (-6.1-5.7 mm), followed by PVP (-7.9-7.1 mm) and AP (-8.5-7.4 mm) images. Intra-observer agreement showed the same trend: -2.8-2.9 mm and -2.9-2.9 mm for readers 1 and 2, respectively, on pre-contrast CT, -2.8-2.9 mm and -3.0-3.2 mm, respectively, on PVP, and -3.2-4.2 mm and -3.4-3.2 mm, respectively, on AP images. Mean tumor diameters differed significantly among the phases in the following increasing order: pre-contrast CT, PVP, and AP images. Conclusion: There was better inter- and intra-observer agreement in size measurements of NET liver metastases on pre-contrast scans than on AP and PVP scans. Pre-contrast CT may be the optimal for measuring NET liver metastases if its accuracy is proven.