• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.40 no.5
• /
• pp.465-475
• /
• 2020

I-D-F curves were induced by Box-Cox transformation using rainfall data from five major cities in Korea: Seoul, Busan, Daegu, Daejeon, and Gwangju, as well as from Sancheong (South Gyeongsang province) and Yeongcheon (North Gyeongsang province) stations. The practicality of the Box-Cox transformation is more scalable than the traditional method of frequency analysis in terms of applicability because it is available even if the analysis data are insufficient to perform general frequency analysis and do not produce an appropriate probability density function. For the case in which rainfall data for the entire period (10-1440 minutes) and short-term period (20, 30, 40, 50 minutes) at the foregoing 7 stations are omitted, there was a relative error of -23.0 % to 14.7 % at a duration of 10 to 60 minutes below the 100-year frequency. Accordingly, rainfall analysis requires inducing I-D-F curves, including for the short term (20, 30, 40, 50 minutes), and if rainfall data are omitted for the short term (20, 30, 40, 50 minutes), it is necessary to increase the existing margin rate depending on the point in order to ensure the safe design of small-scale hydraulic structures.

• The Journal of Engineering Geology
• /
• v.23 no.4
• /
• pp.375-380
• /
• 2013

The concept of safe yield places an emphasis on balancing groundwater withdrawal with groundwater recharge but ignores naturally occurring groundwater discharge. Because streams and their alluvial aquifers are closely linked in terms of water supply and water quality, to be properly understood and managed they must be considered together. Therefore, some districts in Kansas have reevaluated their safe-yield policies to account for natural groundwater discharge and stream-aquifer interactions by amending their safe-yield regulations to include a portion of baseflow as the minimum desirable streamflow (MDS). This study proposes a modified safe-yield policy in which the drought flow is chosen as the MDS. Baseflow separation was conducted from streamflow hydrograph and the results are presented as a flow-duration curve. The exploitable groundwater can be determined by subtracting MDS from the cumulative baseflow. This method was tested in the Musimcheon watershed, which was validated for streamflow using the SWAT-K model. The annually averaged exploitable groundwater in the whole watershed was estimated to be 86 mm. The exploitable groundwater amounts were also estimated for each subwatershed in the Musimcheon watershed.

• Journal of Wetlands Research
• /
• v.15 no.4
• /
• pp.585-593
• /
• 2013

This study aims to investigate inundation characteristics such as inundated area, inundation depth according to variation in return period of design rainfall and to draw a comparison between the inundation characteristics by adapting design storm using dual-drainage model. Lidar data is used to construct terrain data with $1m{\times}1m$ resolution in Cheongju. The designed storm by return periods(10year, 30year, 50year and 200year) are acquired from Intensity Duration Frequency curve, which are distributed in 5 minutes interval using Huff's method. As a results, the inundation volume is linearly increased, but inundated area is gradually increased in accordance with swell of return period for design storm. On the other hands, as a result of calculating discharge capacity for each points, deficit of discharge capacity is not observed using designed storm of 10 year return period at every points. If the return period is increased up more than 10 years, both the deficit of discharge capacity for each PT and entire study area are enlarged drastically.

• Journal of Korea Water Resources Association
• /
• v.45 no.11
• /
• pp.1107-1119
• /
• 2012

The objectives of this study are to develop the flow nomograph for real-time flood forecasting and to assess its applicability in restored Cheonggye stream. The Cheonggye stream basin has the high impermeability and short concentration time and complicated hydrological characteristics. Therefore, the flood prediction method using runoff model is ineffective due to the limit of forecast. Flow nomograph which is able to forecast flood only with rainfall information. To set the forecast criteria of flow nomograph at selected flood forecast points and calculated criterion flood water level for each point, and in order to reflect various flood events set up simulated rainfall scenario and calculated rainfall intensity and rainfall duration time for each condition of rainfall. Besides, using a rating curve, determined scope of flood discharge following criterion flood water level and using SWMM model calculated flood discharge for each forecasting point. Using rainfall information following rainfall scenario calculated above and flood discharge following criterion flood water level developed flow nomograph and evaluated it by applying it to real flood event. As a result of performing this study, the applicability of flow nomograph to the basin of Cheonggye stream appeared to be high. In the future, it is reckoned to have high applicability as a method of prediction of flood of urban stream basin like Cheonggye stream.

• Korean Journal of Microbiology
• /
• v.1 no.1
• /
• pp.38-44
• /
• 1963

According to the experiment on pure-isolation and the related contaminants of Chlorella, the phenomena of the ecological distributions of Chlorella in Korea have been manifested in several areas and also the aim that in going to do culture, biological and physiological study of Chlorella is carried out. Contaminants very oftenly occupied on the colony of the strains taken in order to fulfil pure-isolation of Chlorella, but in accordance with being piled up the minute research on this subject, I can obtain the desirable results as follows: 1. For the pure-isolation, the duration chose the time from May to September 1957 so that may easily isolate from contaminant water with utilizing the antibiotic substances. 2. To take long time, 36-48 hours until growth of nascent through the non-sporulated, it originates from the difference of the cultured media. In addition to the above mention, the mechanism of growth until nascent through the sporulated must not always require the ligh. However the supply of metabolic energy depend upon its nutritional conditions per phase. 3. The culture of Chlorella should be based on the lower culturing except adding especial conditions such as reagent concentration of media, artifical shake of media and other facts due to the natural conditions. And also these strains grew not only in distilled water but 2% NaCl solution without any abnormality in cell it self. I, therefore, guess it is possible to culture in sea-water under phasic environment. 4. In the experiment of ammonia detection, it is caused by the sampling surroundings to contain the minute quantity of ammonia in strain No. M 918; that is the place to be plenty of Carbohydrate on behalf of protein. 5. To compare the absorption curve of chlorophyll of higher plant with that of Chlorella, the absorption zone made mostly the Same ones each other but a little absorption grade dose not clearly appear. The colony which formed giant type grows with intensive colour and green band on surrounding of the colony and after that it was changed into all the green colour and developed up to end. 6. At first phase for a week, the development of Chlorella suspends the normal condition as in vivo but after a few days, the colour of chlorophyll gradually changed into blue-yellow which secrete the mucous substances on the agar media. The cell was flew out the contained substances itself on leaving the cell wall only, or the various micro-organism diffused on the outer-region of the cell.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.21
• /
• pp.9301-9305
• /
• 2014

Background: Pain is one of the most terrifying symptoms for cancer patients. Although most patients with cancer pain need opioids, complete relief of pain is hard to achieve. This study investigated the factors influencing persistent pain-free survival (PPFS) and opioid efficiency. Materials and Methods: A prospective study was conducted on 100 patients with cancer pain, hospitalized at the medical oncology clinic of Akdeniz University. Patient records were collected including patient demographics, the disease, treatment characteristics, and details of opioid usage. Pain intensity was measured using a patient self-reported visual analogue scale (VAS). The area under the curve (AUC) reflecting the pain load was calculated from daily VAS tables. PPFS, the primary measure of opioid efficacy, was described as the duration for which a patient reported a greater than or equal to two-point decline in their VAS for pain. Predictors of opioid efficacy were analysed using a multivariate analysis. Results: In the multivariate analysis, PPFS was associated with the AUC for pain (Exp (B)=0.39 (0.23-0.67), P=0.001), the cumulative opioid dosage used during hospitalisation (Exp (B)=1.00(0.99-1.00), P=0.003) and changes in the opioid dosage (Exp (B)=1.01 (1.00-1.01), P=0.016). The change in VAS score over the standard dosage of opioids was strongly associated with current cancer treatment (chemotherapy vs. others) (${\beta}=-0.31$, T=-2.81, P=0.007) and the VAS for pain at the time of hospitalisation (${\beta}=-0.34$, T=-3.07, P= 0.003). Conclusions: The pain load, opioid dosage, concurrent usage of chemotherapy and initial pain intensity correlate with the benefit received from opioids in cancer patients.

• Journal of the Korea Concrete Institute
• /
• v.26 no.3
• /
• pp.247-254
• /
• 2014

Strain properties of concrete member which acts as an important factor in the stability of the concrete structure in the event of fire, significantly affected the characteristics of the coarse aggregate, which accounts for most of the volume. For this reason, there are many studies on concrete using artificial lightweight aggregate which has smaller thermal expansion deformation than granite coarse aggregate. But the research is mostly limited on concrete using clay-based lightweight aggregate. Therefore, in this study, the high temperature compressive strength and elastic modulus, thermal strain and total strain, high temperature creep strain of concrete was evaluated. As a result, remaining rate of high-temperature strength of concrete using lightweight aggregate is higher than concrete with general aggregate and it is determined to be advantageous in terms of structural safety and ensuring high-temperature strength from the result of the total strain by loading and strain of thermal expansion. In addition, in the case of high-temperature creep, concrete shrinkage is increased by rising loading and temperature regardless of the type of aggregate, and concrete using lightweight aggregate shows bigger shrinkage than concrete with a granite-based aggregate. From this result, it is determined to require additional consideration on a high temperature creep strain in case of maintaining high temperature like as duration of a fire although concrete using light weight aggregate is an advantage in reducing the thermal expansion strain of the fire.

• Journal of Preventive Medicine and Public Health
• /
• v.38 no.2
• /
• pp.203-207
• /
• 2005

Objectives: Recently, the American Diabetes Association (ADA) redefined the criteria of prediabetes, which has lowered the diagnostic level of fasting plasma glucose (FPG) from 110 to 125 mg/dl, down to levels between 100 to 125mg/dl. The purpose of this study was to determine the predictive cutoff level of FPG as a risk for the development of diabetes mellitus in Korean men. Methods: A retrospective cohort study was conducted on 11,423 (64.5%) out of 17,696 males $\leq$30 years of age, and who met the FPG of $\leq$125 mg/dl and hemoglobin A1c of $\leq$ 6.4% criteria, without a history of diabetes, and who were enrolled at the screening center of a certain university hospital between January and December 1999. The subjects were followed from January 1999 to December 2002 (mean follow-up duration; 2.3(${\pm}0.7$) years). They were classified as normal (FPG <100mg/dl), high glucose (FPG $\geq$100mg/dl and <110mg/dl) and impaired fasting glucose (FPG $\geq$110mg/dl and $\leq$125mg/dl) on the basis of their fasting plasma glucose level measured in 1999. We compared the incidence of diabetes between the 3 groups by performing Cox proportional hazards model and used receiver operating characteristic analyses of the FPG level, in order to estimate the optimal cut-off values as predictors of incident diabetes. Results: At the baseline, most of the study subjects were in age in their 30s to 40s (mean age, 41.8(${\pm}7.1$) year). The incidence of diabetes mellitus in this study was 1.19 per 1,000 person-years (95% CI=0.68-1.79), which was much lower than the results of a community-based study that was 5.01 per 1,000 person-years. The relative risks of incident diabetes in the high glucose and impaired fasting glucose groups, compared with the normal glucose group, were 10.3 (95% CI=2.58-41.2) and 95.2 (95% CI= 29.3-309.1), respectively. After adjustment for age, body mass index, and log triglyceride, a FPG greater than 100mg/dl remained significant predictors of incident diabetes. Using the receiver operating characteristic (ROC) curve, the optimal cutoff level of FPG as a predictor of incident diabetes was 97.5 mg/dl, with a sensitivity and a specificity of 81.0% and 86.0%, respectively. Conclusion: These results suggest that lowering the criteria of impaired fasting glucose is needed in Korean male adults. Future studies on community-based populations, including women, will be required to determine the optimal cutoff level of FPG as a predictor of incident diabetes.

• Nutrition Research and Practice
• /
• v.14 no.1
• /
• pp.20-24
• /
• 2020

BACKGROUND/OBJECTIVES: Malnutrition has multiple impacts on surgical success, postoperative complications, duration of hospital stay, and costs, particularly for cancer patients. There are various nutrition risk screening tools available for clinical use. Herein, we aim to determine the most appropriate nutritional risk screening system for esophageal cancer (EC) patients in China. SUBJECTS/METHODS: In total, 138 EC patients were enrolled in this study and evaluated by experienced nurses using three different nutritional screening tools, the Nutrition Risk Screening 2002 tool (NRS2002), the Patient-generated Subjective Globe Assessment (PG-SGA), and the Nutrition Risk Index (NRI).We compared sensitivity, specificity, positive and negative likelihood ratios, and Youden index generated by each of the three screening tools. Finally, cut-off points for all three tools were re-defined to optimize and validate the best nutritional risk screening tool for assessing EC patients. RESULTS: Our data suggested that all three screening tools were 100% sensitive for EC patients, while the specificities were 44.4%, 2.96%, and 59.26% for NRS 2002, PG-SGA, and NRI, respectively. NRI had a higher positive likelihood ratio as well as a higher area under the receiver operating characteristic curve compared to those of NRS 2002 and PG-SGA; although, all three tools had null negative likelihood ratios. After adjusting the cut-off points, the specificity and accuracy for all tools were significantly improved, however, the NRI remained the most appropriate nutritional risk screening system for EC patients. CONCLUSIONS: The NRI is the most suitable (highest sensitivity and accuracy) nutritional risk screening tool for EC patients. The performance of the NRI can be significantly improved if the cut-off point is modified according to the results obtained using MedCalc software.

• The Korean Journal of Pain
• /
• v.22 no.1
• /
• pp.16-20
• /
• 2009

Background: Zaprinast is an inhibitor of phosphodiesterase 5, 6 and 9. Phosphodiesterase inhibitors could produce anti-nociceptive effects by promoting the accumulation of cGMP. We hypothesized that intrathecal zaprinast could attenuate the allodynia induced by chronic constriction injury of the sciatic nerve in rat. Methods: Sprague-Dawley rats were prepared with four loose ligations of the left sciatic nerve just proximal to the trifurcation into the sural, peroneal and tibial nerve branches. Tactile allodynia was measured by applying von Frey filaments to the lesioned hindpaw. The thresholds for the withdrawal responses were assessed. Zaprinast ($3-100{\mu}g$) was administered intrathecally by the direct lumbar puncture method to obtain the dose-response curve and the 50% effective dose ($ED_{50}$). Measurements were taken before and 15, 30, 45, 60, 90, 120, and 180 min after the intrathecal doses of zaprinast. The side effects were also observed. Results: Intrathecal zaprinast resulted in a dose-dependent antiallodynic effect. The maximal effects occurred within 15-30 min and then they gradually decreased down to the baseline level over time in all the groups. There was a dose dependent increase in the magnitude and duration of the effect. The $ED_{50}$ value was $17.4{\mu}g$ (95% confidence intervals; $14.7-20.5{\mu}g$). No severe motor weakness or sedation was observed in any of the rats. Conclusions: Intrathecally administered zaprinast produced a dose-dependent antiallodynic effect in the chronic constriction injury neuropathic pain model. These findings suggest that spinal phosphodiesterase 5, 6 and 9 may play an important role in the modulation of neuropathic pain.