• 한국기계가공학회지
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• 제17권2호
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• pp.37-46
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• 2018

Present research is to evaluate and improve the sealing performance of the duct cap assembly for the ice dispensers through structural analysis. The nonlinear contact problems to check the sealing performance were analyzed using ANSYS software. The results of the analyses related to the sealing performance: the displacement distribution, the contact condition between the cap-silicon and the case, and the pressure distribution on the contact surface, were examined and discussed. Based on the results of the existing design of the duct cap assembly, two cases of the design modifications to improve the sealing performance were introduced. By examining the results of the two cases, a final design improvement plan was proposed and analyzed. It is shown that the sealing performance of the proposed final design is much more favorable than the existing design. The method of structural analysis and design improvement of the duct cap assembly presented in this paper will help improve the sealing performance of the ice dispenser duct caps.

• 한국산학기술학회논문지
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• 제19권5호
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• pp.672-680
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• 2018

본 연구에서는 유한요소해석을 이용하여 냉장고 얼음 디스펜서 작동 시에 덕트 캡 조립체가 열리는 과정을 해석하고 캡의 개방각도를 평가하였으며, 얼음 배출을 원활하게 하기 위하여 캡의 개방각도를 최대화할 수 있는 설계개선안을 도출하였다. 덕트 캡 조립체의 기존설계안에 대하여 모터 작동 시의 입력회전각에 대한 과도구조해석을 수행하였으며 해석결과, 캡의 개방각도는 레버가 강체일 경우에만 가능한 개방각도 상한값의 78%로 나타났다. 캡 개방각도에 미치는 주요 설계인자의 영향을 검토하기 위한 여러 가지의 설계수정안을 도출하고 해석을 수행하였다. 설계수정안의 해석결과, 레버 재질을 탄성계수가 큰 재질로 변경하거나, 지지부의 위치를 모터 측으로 이동하거나, 레버의 축 직경을 증가시키면 개선효과가 높아지는 것으로 나타났다. 구조설계의 변경에 따라 수반되는 제작비용 측면도 고려하면, 얼음 디스펜서 케이스의 기존 구조를 변경하지 않고 레버 재질만 기존의 합성수지에서 알루미늄합금으로 변경하는 설계수정안이 가장 우수한 것으로 나타났다. 결론적으로, 레버 재질을 알루미늄합금으로 변경하면 캡의 개방각도를 상한값의 95%까지 개선할 수 있을 것으로 판단된다. 본 연구에서 제시한 해석 방법 및 결과는 얼음 배출이 원활하도록 덕트 캡 조립체의 구조를 설계하는데 큰 도움이 될 것으로 기대된다.

• 대한조선학회논문집
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• 제55권6호
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• pp.474-481
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• 2018

This paper is to compare by numerical analysis the flow characteristics and propulsion performance of stern with the shape change of K-duct, a pre-swirl duct developed by Korea Research Institute of Ships & Ocean Engineering (KRISO). First, the characteristics of the propeller and the resistance and self-propulsion before and after the attachment of the K-duct to the ship were verified and the validity of the calculation method was confirmed by comparing this result with the model test results. After that, resistance and self-propulsion calculations were performed by the same numerical method when the K-duct was changed into five different shapes. The efficiency of the other five cases was compared using the delivery horsepower in the model scale and the flow characteristics of the stern were analyzed as the velocity and pressure distributions in the area between the duct end and the propeller plane. For the computation, STAR-CCM +, a general-purpose flow analysis program, was used and the Reynolds Averaged Navier-Stokes (RANS) equations were applied. Rigid Body Motion (RBM) method was used for the propeller rotating motion and SST $k-{\omega}$ turbulence model was applied for the turbulence model. As a result, the tangential velocity of the propeller inflow changed according to the position angle change of the stator, and the pressure of the propeller hub and the cap changes. This regulated the propeller hub vortex. It was confirmed that the vortex of the portion where the fixed blade and the duct meet was reduced by blunt change.

• Journal of Advanced Marine Engineering and Technology
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• 제39권1호
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• pp.1-7
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• 2015

최근에 CO2 배출에 대한 환경 규제가 마련되었고, 연료유 가격은 계속해서 상승하고 있다. 이런 상황들을 극복하기 위해 연료소모량을 감소시키고 추진효율을 개선한 에너지 저감 추진장치들이 계속해서 개발되고 있다. 본 논문에는 핸디형 산적화물선에 적용한 PBCF, SCHNEEKLUTH duct, 비대칭 러더 벌브, Mewis duct의 성능 실험을 서술하였다. 그 결과, SCHNEEKLUTH duct가 다른 에너지 저감 장치들에 비해 연료소모량 절감과 추진효율의 향상 측면에서 더 효과적이었다. 또한 SCHNEEKLUTH duct가 거주구 진동에도 효과가 있음을 확인하였다. 그리고 연료소모량은 주기관 de-rating을 통해서도 절감할 수 있었다.

• 생명과학회지
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• 제8권5호
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• pp.479-485
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• 1998

Xenopus 수정란의 동물극분리편에 IGF-1(Insulin-like Growth Factor-1)을 고농도로 처리해 주었을 때의 기관유도효과를 실험하였다. Activin A는 동물극 분리배양조직으로부터 다양한 기관을 분화시키며 이러한 효과는 처리 시간과 농도에 의존한다. 본 연구에서는 activin A 뿐만 아니라 IGF-1을 복합처리하여 특정 기관의 분화양상을 관찰하였다. Activin A는 100ng/ml 의 농도로, IGF-1은 0-500 ng/ml의 범위로 조합 처리하였다. 분리편은 정상배가 st. 43에 이를 때까지 배양하였으며, 이때 activin A를 100ng/ml의 고농도로 처리하면 조직이 파괴되는 것이 일반적이다. 그리고 신관의 발생에 대해서는 activin A와 retinoic acid의 복합처리가 매우 효과적인 방법으로 알려져 있으나, IGF-1의 첨가에 의해 신관을 비롯한 다른 조직들이 분화되었다. 또한, 눈의 분화는 activin A 1-100ng/m1와 IGF-1 500ng/ml의 농도범위에서 일어났다. Activin A의 저농도 (1ng/ml)처리에서는 혈구양세포가 분화하고 배양조직은 풍선처럼 부풀게되나 IGF-1의 첨가로 눈이 발생하게 되어 activin A상의 눈의 발생농도범위가 확대되었다.

• 셀메드
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• 제1권1호
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• pp.5.1-5.3
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• 2011

Molecular events that cause tumor formation enhance a number of HOX genes, called switch genes, coding for RNApolymeraseII transcription factors. Thus, in tumor cells, RNApolymeraseII is more active than in other somatic cells. Amanita phalloides contains amanitin which inhibits RNApolymeraseII. Partial inhibition with amanitin influences tumor cell - but not normal cell - activity. To widen the treatment spectrum, dilutions of Amanita phalloides, containing amanitin, are applied to a patient with mammary duct cancer. For monitoring tumormarkers, different doses of amanitin are applied. The former duplication time of tumor growth represented three months; however within a period of 18 months the patient can be stabilized without further growth of the tumor. There are also no severe symptoms, no liver damage and no continuous erythrocyte deprivation. This new principle of tumor therapy shows high potential to provide a medical treatment.

• 한국해양생명과학회지
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• 제8권2호
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• pp.178-185
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• 2023

본 연구는 낙지의 생식생태 이해에 필요한 수컷 생식기관과 정포의 미세해부학적 구조를 기재하였다. 낙지는 교접완의 유무를 통하여 성을 구별할 수 있는 성적이형을 갖는 종이다. 수컷 생식기관은 정소, 일차수정관, 저정낭, 이차수정관, 정포선, 정포낭으로 구성된다. 정소는 조직학적으로 정세관형이었으며, 수컷 생식세포들은 층상배열상을 보였다. 일차수정관은 정소와 저정낭을 연결하는 관으로 상피층과 결합조직으로 이루어져 있었다. 저정낭은 일차수정관과 이차수정관의 사이에 위치하며, 상피층은 상피세포와 점액세포로 구성된다. 점액세포는 AB-PAS (pH 2.5) 반응에서 푸른색, AF-AB (pH 2.5) 반응에서 보라색으로 반응하였다. 이차수정관은 저정낭과 정포선을 연결하는 짧은 관으로 내강에 주름이 발달하였다. 정포선은 다수의 관상선으로 이루어져 있었으며, 분비세포는 호산성 과립을 가지고 있었다. 정포낭은 주머니 모양으로 내강에 주름이 발달하였으며, 상피층에 공포상의 분비세포가 존재하였다. 정포는 길이 약 83.5 mm로 전방부의 당김사, 중간부의 발사체와 고정체, 후방부의 정자 저장부로 구성되어 있었다.

• 생명과학회지
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• 제9권5호
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• pp.504-509
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• 1999

The trend of organogenesis in Xenopus presumptive ectoderm was studied by combined dose of activin A and IGF-1(insulin-like growth factor-1). In reference study of Asashima and his colleagues, the inductive patterns of various organs were reported with activin, the potent mesoderm inducing factor. In present study, the inducing pattern was cleared with combined-dose of concentration 1-100 ng/ml activin A and IGF-1. In addition, the result from single treatment of activin A was compared with former study. As a result, eye was differentiated in 5-20% of explants at 10 and 50 ng/ml concentrative combination of activin A. Otic vesicle was appeared in the entire concentrative combination of IGF-1. Pronephric duct was induced 19-38% of explants at the concentration of activin A 100 ng/ml by adding IGF-1. The comparison of single treatment of activin A was showed some difference in dose-dependent inducing pattern.

• 한국환경과학회지
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• 제20권10호
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• pp.1221-1232
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• 2011

We investigated the toxic effects of difenoconazole on the development in the African clawed frog, Xenopus laevis. To test the toxic effects, frog embryo teratogenesis assays using Xenopus were performed. Embryos were exposed to various concentrations of difenoconazole (0-30 ${\mu}M$). $LC_{100}$ for difenoconazole was 30 ${\mu}M$, and the $LC_{50}$ determined by probit analysis was 27.19 ${\mu}M$. Exposure to difenoconazole concentrations ${\geq}$5 ${\mu}M$ resulted in 10 different types of severe external malformation. Histological examinations revealed dysplasia of the eye, heart, liver, somatic muscle, and swelling of the pronephric ducts. The tissue-specific toxic effects were investigated with an animal cap assay. Blood cells were normally induced at a high frequency by mSCF and activin A. However, the induction of blood cells was strongly inhibited by the addition of difenoconazole. Electron micrographs of tested embryos showed the degeneration of somatic muscle and the shrinkage of microvilli on pronephric duct. The gene expression of cultivated animal cap explants was investigated by reverse transcriptase-polymerase chain reaction (RT-PCR). It revealed that the expression of the blood-specific marker(${\beta}$-globin II) and muscle-specific marker (XMA) were more strongly inhibited than the neural-specific marker(XEn2) by the addition of difenoconazole.

• 대한기계학회논문집B
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• 제23권6호
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• pp.722-733
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• 1999

The wall pressure fluctuations of a turbulent boundary layer over a flat plate have been investigated in an anechoic wind tunnel facility. The anechoic wind tunnel consists of acoustically-lined duct, muffler, and splitter-type silencer for noise suppression and vanes for reducing head losses involved. To improve spectra characteristics in high frequency range, a 1/8" pressure-type microphone sensor, which has a pin-holed cap of various diameters, was employed in this experiment. It was shown that the pin-holed microphone sensor with a dimensionless diameter $d^+$ of 7.1 resolved the high frequency pressure fluctuations most effectively among ones with various pin-hole diameters. The measured wall pressure spectra in terms of three types of scaling parameters were in good agreement with other experimental and numerical results. The pressure events of high amplitude were found to contribute to total fluctuating pressure energies in the turbulent boundary layer significantly and supposed to radiate to the far-field effectively.