• Title/Summary/Keyword: Dual-Screen

Search Result 53, Processing Time 0.027 seconds

Caspase-11 Promoter-GFP Construct as a Dual Reporter of Cytotoxicity and Inflammation

  • Shin, Ki-Soon;Kang, Shin-Jung
    • Animal cells and systems
    • /
    • v.10 no.2
    • /
    • pp.73-77
    • /
    • 2006
  • Caspase-11 has been known as a dual regulator of apoptosis and inflammatory response. An unusual feature of caspase-11 is that its expression is induced by apoptotic or proinflammatory stimuli. Utilizing these unusual features of caspase-11, we have developed a simple and sensitive assay method to screen pro- or anti-apoptotic/inflammatory molecules. To develop this assay method, we generated a reporter construct where GFP expression is regulated by caspase-11 promoter. When several types of cultured cells were transfected with this reporter construct and subsequently treated with various apoptotic or proinflammatory molecules, expression of GFP by the activation of caspase-11 promoter was easily detected by fluorescence microscopy or spectrofluorometry. In addition, a reduction of the GFP fluorescence was detected when an agent reported to suppress caspase-11 induction was applied. These results suggest that our reporter system can be used to screen pro- or anti-apoptotic/inflammatory molecules.

Correlationship among Smartphone Screen Time, Cervical Alignment, and Muscle Function in University Students

  • Hyungyu Cha;Seonyoung Hwang;Jinyoung Eo;Hyein Ji;Jiwon Han;Wonjae Choi
    • Physical Therapy Rehabilitation Science
    • /
    • v.11 no.4
    • /
    • pp.446-453
    • /
    • 2022
  • Objective: The popularization of smartphones can lead to abnormal cervical alignment in university students. The aim of this study was to investigate the relationship among smartphone screen time, cervical alignment, and muscle function in university students. Design: Cross-sectional study. Methods: Seventy-five university students participated in the study. They completed the evaluation of cervical alignment and muscle function, such as handgrip strength, proprioception, and muscle quality (tone, stiffness, and relaxation time). All participants recorded their general characteristics and individual smartphone screen time before the evaluation. They were evaluated craniovertebral angle (CVA) using smartphone application (angle meter 360) for measuring cervical alignment. The muscle function was assessed using a digital hand-held dynamometer, dual inclinometer, and MyotonPRO device. Results: Of all participants, twenty-five university students had forward head posture (CVA<49°, 33.33%). Independent t-test revealed that there were significant differences on smartphone screen time, muscle stiffness, and muscle relaxation between the participants with and without forward head posture (p<0.05). There were significant correlations between the smartphone screen time and the CVA, muscle tone, and muscle relaxation (r=-0.493, 0.250, and -0.500, respectively). Conclusions: The results indicate that the university students with forward head posture had high smartphone screen time and muscle stiffness compared to the students without forward head posture, and smartphone screen time might be associated with cervical alignment and muscle quality.

Analysis of Wireless Signal Strength in Indoor Environment with Film-Type Dual-Band Frequency Selective Structure (필름형 이중 대역 주파수 선택 구조가 적용된 실내 환경의 무선신호강도 분석)

  • Cho, Sung-Sil;Lee, Sang-Hwa;Yoon, Sun-Hong;Hong, Ic-Pyo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.29 no.1
    • /
    • pp.1-9
    • /
    • 2018
  • In this paper, we propose a film-type dual-band frequency selective structure for improving the wireless communication environment in a building. The proposed frequency-selective structure is a miniaturized structure that can control the resonant frequencies of 2.4 GHz and 5 GHz dual band through simple design parameters. We fabricated the frequency-selective surface by screen printing using conductive ink on a thin transparent film and confirmed its performance by measurement. We analyzed the attenuation performance of the unnecessary signal from the outside when the frequency-selective structure designed using the software to analyze the propagation environment performance is applied to the building. To verify the analytical results, the signal strength of the indoor environment was measured by applying the frequency-selective film fabricated on the inner wall of the actual building. The measurement results show that the dual-band frequency-selective film has 29.4 dB and 15.94 dB attenuation performance in the 2.4 GHz and 5 GHz, respectively.

A study on the possibility of using dual task performance as a screening test for driving ability of elderly drivers (노인운전자 운전능력 선별검사로서 이중과제수행의 활용 가능성 연구)

  • Shin, Su-Jung
    • Journal of Convergence for Information Technology
    • /
    • v.11 no.4
    • /
    • pp.161-167
    • /
    • 2021
  • This study was conducted to identify the relationship between the dual task performance and driving behavior of the elderly driver in order to identify whether the dual task can be utilized as a test to screen the driving ability of the elderly driver. We surveyed general information and driving-related information for 32 normal elderly drivers, and evaluated Y-DuCog(Yonsei-Dual task Cognitive screening) and the K-DBQ (Korean-Driving Behavior Questionnaire). As a result of the study, the performance of the dual task using the pegboard task and the animal name speaking showed a significant correlation with the score of the violation domain of K-DBQ. With this study, it was possible to confirm the possibility as a test for discrimination of driving ability.

A Comparative Study on Image Quality of Breast Image Tests using ACR Phantom (ACR 팬텀을 이용한 시스템별 유방검사 영상의 비교 연구)

  • Hong, Dong-Hee;Jung, Hong-Ryang;Lim, Cheong-Hwan
    • Journal of radiological science and technology
    • /
    • v.29 no.4
    • /
    • pp.241-247
    • /
    • 2006
  • Recently, interests and utilization on Computed Radiography(CR) and Digital Radiography(DR) tends to increase owing to an introduction of Picture Archiving and Communication System(PACS) and an accuracy control of special medical equipment for a breast imaging examination. This study was intended to compare and analyze a detector's imaging quality by each system to be used for the breast imaging examination by using ACR Phantom used at the accuracy control. As an evaluation method, a significance and reliability of image's value using the ACR Phantom was analyzed by using SPSS program. The results are followed. 1. For the fiber, there was 3.9 score in Screen-Film, 4.2 score in CR($50{\mu}m$), 3.2 score in CR($100{\mu}m$), and 4.2 score in DR. There was the high score in the order of CR($50{\mu}m$), DR, Screen-Film, and CR($100{\mu}m$)(P<0.05). 2. For the calcification, there was 2.7 score in Screen-Film, 2.5 score in CR($50{\mu}m$), 2.0 score in CR($100{\mu}m$), and 2.9 score in DR. There was the high score in the order of DR, Screen-Film, CR($50{\mu}m$), and CR($100{\mu}m$).(0.025(P<0.05). 3. For Mass, there was 3.8 score in Screen-Film, 3.8 score in CR($50{\mu}m$), 3.6 score in CR($100{\mu}m$), and 4.5 score in DR. There was the high score in the order of DR, CR($50{\mu}m$), Screen-Film, and CR($100{\mu}m$) (P<0.1). 4. As the total score, there was 10.4 score in Screen-Film, 10.6 score in CR($50{\mu}m$), 8.7 score in CR($100{\mu}m$), and 11.3 score in DR. There was the high score in the order of DR, $CR(50{\mu}m$), Screen-Film, and $CR(100{\mu}m$). As shown in the above results, it can be known that DR and Screen-Film System has higher image quality than CR. But, DR has unstability caused by element, and Screen-Film has the low image quality caused by artifact as disadvantages. When Dual-Side CR($50{\mu}m$) was used among CR systems which had the problem of low image quality, it was indicated that there was no difference with Screen-Film System. Because the radiation imaging examination tends to become digitalized, each system for the breast imaging examination will need to be developed and supplemented.

  • PDF

The Effects of Dual Task Performance on Balance and Muscle Activity in Adults with Ankle Instability with Smartphones (스마트폰을 이용한 이중과제 수행이 발목 불안정성을 가진 성인의 균형과 근 활성도에 미치는 영향)

  • Min-Kyu Kim;Hoe-Song Yang;Young-Dae Yoo;Hyo-Jeong Kang;Chan-Joo Jeong
    • Journal of The Korean Society of Integrative Medicine
    • /
    • v.11 no.1
    • /
    • pp.21-29
    • /
    • 2023
  • Purpose : Using a smartphone while walking districts attention and increases the risk of losing balance or falling. Ankle instability is caused by decreased muscle strength and decreased neuromuscular ability leading to postural control problems. Dual tasks increases the risk of falls by reducing postural control in adults with ankle instability. This study aimed to investigate the effect of performing a dual task on balance and muscle activity in adults with ankle instability using a smartphone. Methods : Forty-nine individuals with ankle instability participated in this study. A game of finding the wrong picture was performed using a smartphone in the dual task, and only looking at the blank screen of a smartphone was evaluated in the single task. The participants randomly performed single and dual task to evalutate balance and muscle atcitivy. Balance was evaluated using the Biodex balance system (BBS), and muscle activity was evaluated using surface EMG. Muscle activity of the gastrocnemius and tibialis anterior was measured at the same time as balance. Results : The results of this study showed that overall, anteior/posterior, and medial/lateral balance indices all showed significant differences when performing the dual task compared with those during the single task (p<.05). The muscle activity results showed a significant difference compared with that of the gastronemius muscle on the nondominant side during the dual task (p>.05). Conclusion : The results of this study showed that maintaining balance is more difficult when performing the dual task than during the single task, and only the muscle activity of the nondominant gastrocnemius muscle decreased. The dual task causes a decrease in concentration for postural control, which negatively affects postural stability. Individuals with ankle ankle instability should refrain from performing dual tasks, such as using smartphones, to prevent ankle damage.

Image Restoration in Dual Energy Digital Radiography using Wiener Filtering Method

  • Min, Byoung-Goo;Park, Kwang-Suk
    • Journal of Biomedical Engineering Research
    • /
    • v.8 no.2
    • /
    • pp.171-176
    • /
    • 1987
  • Wiener filtering method was applied to the dual energy imaging procedure in digital radiography(D.R.). A linear scanning photodiode arrays with 1024 elements(0.6mm H 1.3mm pixel size) were used to obtain chest images in 0.7 sec. For high energy image acquisition, X-ray tube was set at 140KVp, 100mA with a rare-earth phosphor screen. Low energy image was obtained with X-ray tube setting at 70KVp, 150mA. These measured dual energy images are represented in the vector matrix notation as a linear discrete model including the additive random noise. Then, the object images are restored in the minimum mean square error sense using Wiener filtering method in the transformed domain. These restored high and low energy images are used for computation of the basis image decomposition. Then the basis images are linearly combined to produce bone or tissue selective images. Using this process, we could improve the signal to noise ratio characteristics in the material selective images.

  • PDF

Improved Adhesion of DLC Films by using a Nitriding Layer on AISI H13 Substrate

  • Park, Min-Seok;Kim, Dae-Young;Shin, Chang-Seouk;Kim, Wang Ryeol
    • Journal of the Korean institute of surface engineering
    • /
    • v.54 no.6
    • /
    • pp.307-314
    • /
    • 2021
  • Diamond-like carbon (DLC) is difficult to achieve sufficient adhesion because of weak bonding between DLC film and the substrate. The purpose of this study is to improve the adhesion between substrate and DLC film. DLC film was deposited on AISI H13 using linear ion source. To improve adhesion, the substrate was treated by dual post plasma nitriding. In order to define the mechanism of the improvement in adhesive strength, the gradient layer between substrate and DLC film was analyzed by Glow Discharge Spectrometer (GDS) and Scanning Electron Microscope (SEM). The microstructure of the DLC film was analyzed using a micro Raman spectrometer. Mechanical properties were measured by nano-indentation, micro vickers hardness tester and tribology tester. The characteristic of adhesion was observed by scratch test. The adhesion of the DLC film was enhanced by active screen plasma nitriding layer.