• 한국방사선학회논문지
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• 제5권1호
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• pp.27-35
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• 2011

이중에너지 X-ray 골밀도 측정기를 이용하여 폐경 전 여성들을 대상으로 골밀도에 영향을 규명하기 위하여 폐경기 이후에 증가하는 골다공증의 예방에 기여하고자 수행하였다. 연구 대상자의 골감소증은 20.2%였으며, 골밀도 수치를 예측할 수 있는 가장 중요한 인자는 연령 이었다. 연령이 높을수록 유의하게 낮은 골밀도를 보였다. 운동에 있어서는 운동을 안하는 것보다 운동을 하는 것이 골밀도에 더 좋은 영향을 미치며, 적정한 운동을 하는 것이 골밀도에 좋은 영향을 미치는 것으로 나타났다. 식생활에 따른 골밀도는 채식 위주의 식사보다는 육식위주의 식사를 선호하는 경우 골밀도에 유의한 영향을 미치는 것으로 나타났고, 생리주기가 짧을수록 골밀도가 유의하게 높았다. 골밀도와 관련요인에 대한 다중회귀분석에서는 연령이 증가할 유의하게 골밀도가 낮게 나타나 연령이 골다공증의 위험요인으로 나타났다.

• Fibers and Polymers
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• 제5권3호
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• pp.245-251
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• 2004

Poly(trimethylene terephthalate-co-trimethylene 2,6-naphthalate)s (P(TT-co-TN)s) with various copolymer composition were synthesized, and their chain structure, thermal property and crystalline structure were investigated by using $^1$H-NMR spectroscopy, differential scanning calorimetry (DSC) and wide-angle X-ray diffraction (WAXD), respectively. It was found from sequence analysis that all the P(TT-co-TN) copolymers synthesized have a statistical random distribution of TT and TN units. It was also observed from DSC thermograms that the glass transition temperature increases linearly with increasing the TN comonomer content, whereas the melting temperature of copolymer decreases with increasing the corresponding comonomer content in respective PTT- and PTN-based copolymer, showing pseudo-eutectic melting behavior. All the samples melt-crystallized isothermally except for P(TT-co-66 mol % TN) exhibit multiple melting endotherms and clear X-ray diffraction patterns. The multiple melting behavior originates from the dual lamellar population and/or the melting-recrystallization-remelting. The X-ray diffraction patterns are largely divided into two classes depending on the copolymer composition, i.e., PTT and PTN $\beta$-form diffraction patterns, without exhibiting cocrystallization.

• 대한디지털의료영상학회논문지
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• 제13권2호
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• pp.59-62
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• 2011

In this experiment, how DEXA(Dual-energy X-ray Absorptiometry) bone mineral density was measured using the equipment. In order to maintain the same measurement conditions, bone mineral density measurements of 10 cm thick phantom, with an actual patient at a point when examining the same conditions(100 kVp, 1 mA) and then out to the five doses of radiation and its average was calculated by dividing measured. X-ray dose rate measured at the Research Institute, Sword of the gamma survey meters calibrated MEDCOM Ltd. (Inspector GM counter tube) was used, calibration factor is 1.15. On a horizontal plane around the patient, depending on the distance was significantly reduced dose rate. In addition, orientation $0^{\circ}$ head end was higher in the direction of the highest dose rate, $0^{\circ}$ $180^{\circ}$ direction from the direction towards the higher dose rate reduced to some extent in the direction of all the $120^{\circ}$ were able to identify.

• Korean Journal of Radiology
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• 제23권9호
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• pp.854-865
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• 2022

Photon-counting detector (PCD) CT is a new CT technology utilizing a direct conversion X-ray detector, where incident X-ray photon energies are directly recorded as electronical signals. The design of the photon-counting detector itself facilitates improvements in spatial resolution (via smaller detector pixel design) and iodine signal (via count weighting) while still permitting multi-energy imaging. PCD-CT can eliminate electronic noise and reduce artifacts due to the use of energy thresholds. Improved dose efficiency is important for low dose CT and pediatric imaging. The ultra-high spatial resolution of PCD-CT design permits lower dose scanning for all body regions and is particularly helpful in identifying important imaging findings in thoracic and musculoskeletal CT. Improved iodine signal may be helpful for low contrast tasks in abdominal imaging. Virtual monoenergetic images and material classification will assist with numerous diagnostic tasks in abdominal, musculoskeletal, and cardiovascular imaging. Dual-source PCD-CT permits multi-energy CT images of the heart and coronary arteries at high temporal resolution. In this special review article, we review the clinical benefits of this technology across a wide variety of radiological subspecialties.

• 대한의용생체공학회:의공학회지
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• 제9권2호
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• pp.185-194
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• 1988

The dual-energy technique win used to separate the bone-only and tissue-only images from the conventional chest images. The equivalent thickness of the basic materials are estimated from low and high energy images of a given complex materials using the attenuation coefficient of ma serial componens. We showed that the image quality of dual-energy imaging method can be influenced by the ponlinearity and noise components of system and spectrum distributions The quantitative analysis of Calcium component was performed by dual-energy technique and it is shown that the concentration of the Calcium could be accurately estimated within 5% error range.

• Korean Chemical Engineering Research
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• 제61권3호
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• pp.463-471
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• 2023

Nitrogen-rich carbon dots (NDots) were synthesized by using uric acid as carbon and nitrogen sources. The as-synthesized NDots showed strong dual emissions at 420 nm and 510 nm with excitation at 350 nm and 460 nm, respectively. The physicochemical analyses such as X-ray photoelectron spectroscopy, Transmission electron microscopy and Fourier transform infrared spectroscopy were used to analyze the chemical, physical and morphological structures of NDots. The as-synthesized NDots exhibited wide linear range (0-100 µM) and very low detection limit (124 nM) in Ag⁺ ion sensing. In addition, Ag⁺ saturated NDots could be used as an EDTA sensor by the EDTA induced PL recovery.

• 한국방사선학회논문지
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• 제15권1호
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• pp.63-70
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• 2021

골밀도검사에서 측정값에 영향을 주는 요인 중 하나인 방사선 조영제는 진단 목적으로 사용되어 조직 등에 흡수되어 골밀도 측정값을 높이는 효과가 있어, 골밀도검사 시행 전에는 될 수 있으면 피하고 있다. 이러한 방사선 조영제와는 다른 물리적 특성과 작용기전을 갖는 MRI 조영제는 금속원소인 가돌리늄 기반으로 방사선 불투과성 특징을 가지고 있어 일반적으로 방사선을 이용한 검사 전에 MRI 검사를 선 시행하고 있다. 본 연구에서는 MRI 조영제가 이중에너지 X-선 흡수법을 이용한 골밀도검사에 미치는 영향을 알아보고자 하였다. 가돌리늄 기반의 MRI 조영제 2종을 아크릴 수조에 용량별로 주입하여 인체모형 척추 팬텀을 넣고, 각 주입량 종류별로 5회씩 총 30회 scan 하여 L1-L4 번까지의 골밀도와 T-score를 분석하였다. 측정된 2종의 조영제별 Total(L1-L4) 골밀도의 평균값은 가도테레이트 메글루민성분 0mL, 7.5mL, 15mL일때, 각각 0.952±0.052, 0.957±0.050, 0.956±0.05 g/㎠로 나타났으며, 가도부트롤성분 0mL, 5mL, 10mL일 때, 각각 0.953±0.001, 0.954±0.001, 0.945±0.001g/㎠로 모든 부위에서 통계적으로 유의한 차이는 없었다(p>0.05). Total (L1-L4) T-score의 평균값은 가도테레이트 메글루민성분은 0mL, 7.5mL, 15mL일 때, 각각 -0.46±0.05, -0.4±0, -0.42±0.04로 나타났으며, 가도부트롤성분 0mL, 5mL, 10mL일 때, 각각 -0.46±0.05, -0.46±0.05, 0.5±0.00으로 모든 부위에서 통계적으로 유의한 차이는 없었다(p>0.05). 본 실험에서는 MRI 조영제는 이중에너지 X-선 흡수법을 이용한 골밀도검사에 영향이 없는 것으로 나타났으나, 임상 대상이 아닌 제한적 조건의 인체 모형 팬텀을 사용하여 조영제의 배출시간에 영향을 주는 신장 기능, 신체 상태 등이 고려되지 못한 제한점이 있어 추후 추가적인 임상연구 진행이 필요할 것으로 사료된다.

• 보건교육건강증진학회지
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• 제15권1호
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• pp.179-194
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• 1998

This study focused on the body composition of Korean Basketball Players in Dual X -ray Absorptiometry. The principal subjects of this study were 10 Basketball Players who participated in the process of Dual Energy X -ray Absorptiometry at K.H. University Hospital for 8 months from Sept. 1. 1996 to April, 30. 1997. On the basis of the these measurements, the authors calculated physical indices and total fat percent. On the results of bone densitometry, the author analyzed body fat weight, body composition according to body position, bone mineral density and discerned the difference between the fatness which was calculated indirectly and which gained from the bone densitometry. 1. General Characteristics The mean age of the subjects was 20.4$\times$1.35 year. 2. Physical. Measurement The mean physical growth and development of the subjects were superior to standard value of the average Koreans 3. Body Fat by Physical Measurement Body surface area was 2.019$\times$0.111$m^2$, body volume was 74.4$\times$7.2$\ell$, body density was 1.041$\times$0.007$\ell$/kg, and body fat percent was 24.9$\times$2.9%. 4. Body Fat by Bone Densitometry Total body fat percent was 15.17$\times$2.19% and according to body position that of upper limb was 1.62%, that of lower limb was 5.55%, that of trunk was 7.06% and that of head was 1.05%. There was significant difference between the amounts of body fat from the methods used in this study; that from physical measurements and from bone densitometry method could be said most desirable. 5. Body composition According to Body Position Trunk was highest at 46.7%, lower limb was 36.0%, upper limb was 10.6%, and head was 6.7% in order. 6. Bone Mineral Content and Bone Density In bone mineral amount by body position, that of upper limb was 466.9$\times$46.4g, that of lower limb was 1,424.1$\times$154.0g, that of trunk was 1,343.0$\times$150.3g, and total bone mineral content was 3,786.8$\times$348.4g(4.78$\times$0.13%). Bone mineral density by body position, that of upper limb was 0.758$\times$0.072g/$\textrm{cm}^2$, that of lower limb was 1,342$\times$0.095g/$\textrm{cm}^2$, that of trunk was 1,169$\textrm{cm}^2$0.082g/$\textrm{cm}^2$, that of head was 1,742$\times$0.154g/$\textrm{cm}^2$ and total bone mineral density was 1,204$\times$0.077g/$\textrm{cm}^2$.

• Korean Journal of Radiology
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• 제24권12호
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• pp.1249-1259
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• 2023

Objective: This study aimed to evaluate the clinical outcomes and cost-effectiveness of dual-energy X-ray absorptiometry (DXA) for osteoporosis screening. Materials and Methods: Eligible patients who had and had not undergone DXA screening were identified from among those aged 50 years or older at Kaohsiung Veterans General Hospital, Taiwan. Age, sex, screening year (index year), and Charlson comorbidity index of the DXA and non-DXA groups were matched using inverse probability of treatment weighting (IPTW) for propensity score analysis. For cost-effectiveness analysis, a societal perspective, 1-year cycle length, 20-year time horizon, and discount rate of 2% per year for both effectiveness and costs were adopted in the incremental cost-effectiveness (ICER) model. Results: The outcome analysis included 10337 patients (female:male, 63.8%:36.2%) who were screened for osteoporosis in southern Taiwan between January 1, 2012, and December 31, 2021. The DXA group had significantly better outcomes than the non-DXA group in terms of fragility fractures (7.6% vs. 12.5%, P < 0.001) and mortality (0.6% vs. 4.3%, P < 0.001). The DXA screening strategy gained an ICER of US$ -2794 per quality-adjusted life year (QALY) relative to the non-DXA at the willingness-to-pay threshold of US$ 33004 (Taiwan's per capita gross domestic product). The ICER after stratifying by ages of 50-59, 60-69, 70-79, and ≥ 80 years were US$ -17815, US$ -26862, US$ -28981, and US$ -34816 per QALY, respectively. Conclusion: Using DXA to screen adults aged 50 years or older for osteoporosis resulted in a reduced incidence of fragility fractures, lower mortality rate, and reduced total costs. Screening for osteoporosis is a cost-saving strategy and its effectiveness increases with age. However, caution is needed when generalizing these cost-effectiveness results to all older populations because the study population consisted mainly of women.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2012년도 춘계학술발표대회
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• pp.369-372
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• 2012

대사성 골 질환인 골다공증(Osteoporosis)의 조기 진단을 위한 골 밀도를 측정하는 방법이 최근 연구되고 있다. 골 밀도 영상은 이중 에너지 X 선 흡수법에 의해 측정되는데, 영상에 존재하는 잡음은 뼈 영역 추출과 골 밀도 계산에 어려움을 주고 있다. 따라서 본 논문에서는 최근 신호처리 분야에서 폭넓게 사용되고 있는 sparse 표현을 도입하여 X 선 영상의 잡음을 제거하는 방법을 제안한다. 실험을 통해 제안한 잡음 제거 방법의 결과가 기존의 방법에 비해 개선됨을 MSR(Mean to Standard deviation Ratio)과 CNR(Contrast to Noise Ratio)을 통해 확인하였다.