• 전자공학회논문지A
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• 제28A권5호
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• pp.361-369
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• 1991

The optics and the signal processor of dual beam laser Doppler velocimeter(LDV) was fabricated. By using the dual beam and the forward scattering, the optics part of LDV was fabricated. And the signal processor of LDV was designed by the frequency counter type using new 11:6 period timing device in order to remove error signals, and was made of the reference clock of a 500 MHz ECL oscillator. Doppler frequencies from 10KHz to 70MHz can be measured using the signal processor. In the accuracy of the period counting part, from 1.81x10**-4% to 1.27% is estimated, and in the accuracy of the validation logic part, from 0.78% to 14.78% is estimated.

• 대한전자공학회논문지
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• 제24권2호
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• pp.196-200
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• 1987

The following methods are proposed for implementing digital dual tone multi-frequency (DTMF) receiver: using infinite impulse response(IIR) digital filters, period-counting algorithm, discrete Fourier transform(DFT), and fast Fourier transform(FFT)[2]. The PARCOR(Partical Correlation) analysis method which has been widly used in the speech signal processing area is applied to the dual tone multi-frequency(DTMF) signal detection. This method is easy to implement digitally and stronger to digit simulation of speech than any other methods proposed up to date. Since sampling rate of 4KHz is used in the DTMF receiver for the detection of input DTMF signal originally sampled at 8KHz, it effects two times higher multiplexing efficiency.

• 한국정밀공학회지
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• 제25권8호
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• pp.29-36
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• 2008

An optical rotary encoder is easy to implement for automation system applications. In particular, the output of the encoder has a digital form pulse, which is also easy to be connected to a popular digital controller. By using an incremental encoder and a counting device, it is easy to measure angular displacement, as the number of the output pulses is proportional to the rotational displacement. This method can only detect the angular placement once a pulse signal comes out of the encoder. The angular displacement detection period is strongly subject to the change of the angular displacement in case of ultimate low velocity range. They have ultimate long detection period or cannot even detect angular displacement at near zero velocity. This paper proposes an algorithm for detecting angular displacement by using a dual encoder system with two encoders of normal resolution. The angular displacement detecting algorithm is able to keep detection period moderately at near zero velocity and even detect constant angular displacement within nominal period. It is useful for motion control applications in case of changing rotational direction at which there occurs zero velocity. In this paper, various experimental results are shown for the angular displacement detection algorithm.

• Nuclear Engineering and Technology
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• 제52권10호
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• pp.2346-2352
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• 2020

Dual-energy x-ray absorptiometry (DXA) is the noninvasive method to diagnose osteoporosis disease characterized by low bone mass and deterioration of bone tissue. Many global companies and research groups have developed the various DXA detectors using a direct photon-counting detector such as a cadmium zinc telluride (CZT) sensor. However, this approach using CZT sensor has some drawback such as the limitation of scalability by high cost and the loss of efficiency due to the requirement of a thin detector. In this study, a SiPM based DXA system was developed and its performance evaluated experimentally. The DXA detector was composed of a SiPM sensor coupled with a single LYSO scintillation crystal (3 × 3 × 2 ㎣). The prototype DXA detector was mounted on the dedicated front-end circuit consisting of a voltage-sensitive preamplifier, pulse shaping amplifier and constant fraction discriminator (CFD) circuit. The SiPM based DXA detector showed the 34% (at 59 keV) energy resolution with good BMD accuracy. The proposed SiPM based DXA detector showed the performance comparable to the conventional DXA detector based on CZT.

• 대한방사선기술학회지:방사선기술과학
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• 제42권1호
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• pp.9-17
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• 2019

Although digital mammography is a representative method for breast cancer detection. It has a limitation in detecting and classifying breast tumor due to superimposed structures. Machine learning, which is a part of artificial intelligence fields, is a method for analysing a large amount of data using complex algorithms, recognizing patterns and making prediction. In this study, we proposed a technique to improve the diagnostic accuracy of energy-selective mammography by training data using the machine learning algorithm and using dual-energy measurements. A dual-energy images obtained from a photon-counting detector were used for the input data of machine learning algorithms, and we analyzed the accuracy of predicted tumor thickness for verifying the machine learning algorithms. The results showed that the classification accuracy of tumor thickness was above 95% and was improved with an increase of imput data. Therefore, we expect that the diagnostic accuracy of energy-selective mammography can be improved by using machine learning.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.422-424
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• 2002

The accuracy of DXA(Dual Energy X-ray Absorptiometry) highly depends on the detection and separation capability of dual energy X-ray X-ray photons. In addition both of scan time and patient exposure are affected by detection efficiency. A CZT detector with a good energy resolution and high detection efficiency was evaluated for the application of bone densitometry. Its performance was compared to a photomultiplier tube with a NaI(T1) scintillator in terms of energy resolution, detection efficiency and the accuracy of bone mineral density measurement. The comparison study was performed with CZT detector and PM tube using DXA equipments(OSTEO Plus, OSTEO Prima, ISOL Technology). The energy spectrum was acquired using MCA(Multi-Channel Analyzer). The used X-ray energy ranged from 20keV to 86keV. The MCA result of the CZT detector showed a slightly sharper energy spectrum than that of NaI(T1). Detection efficiency of the CZT detector at 59.5keV was 1.4 times better. Remarkably the final results of bone mineral density measurements demonstrate only less than 1% difference. The CZT detector appears to have many benefits for the application of bone densitometry. Its excellent energy resolution can enhance the counting accuracy of dual energy X-ray spectrum. Furthermore its compactness in physical dimension and no cooling requirement will be additional benefits for a more compact and accurate bone densitometer.

• Molecules and Cells
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• 제42권6호
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• pp.448-459
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• 2019

The phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathway is a promising target for gastric cancer (GC) treatment; however the efficacy of PI3K/mTOR dual inhibitors in GC has not yet been maximized. Additionally, the effect of autophagy regulation by PI3K/mTOR dual inhibitors has not been clearly elucidated in GC treatment. We aimed to show that our newly developed PI3K/mTOR dual inhibitor, CMG002, when combined with an autophagy inhibitor, chloroquine (CQ), potently induces effective cancer cell death in Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) cells, where both the PI3K/AKT/mTOR and autophagy pathways play important roles in disease pathogenesis. EBV- and mock-infected AGS and NUGC3 GC cell lines were treated with CMG002 +/- CQ. PI3K/AKT/mTOR signaling pathway mediators, cellular apoptosis and autophagy markers were confirmed by Western blot assay. Cell viability was assessed using the Cell Counting Kit-8 (CCK-8) assay. CMG002 effectively blocked the PI3K/AKT/mTOR pathway by markedly decreasing phosphorylation of AKT and its downstream mediator S6. CMG002 induced G0/G1 cell cycle arrest and enhanced apoptotic cell death in AGS and NUGC3 cells, particularly EBV-infected cells compared with mock-infected cells, as confirmed by flow cytometric analyses and TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assays. The combination of CMG002 plus CQ synergistically increased apoptotic cell death in EBV-infected GC cell lines when compared with CMG002 alone (P < 0.05). Our results suggest that the new PI3K/mTOR dual inhibitor, CMG002, when used in combination with the autophagy inhibitor, CQ, provides enhanced therapeutic efficacy against EBVaGC.

• Journal of Radiation Protection and Research
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• 제26권3호
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• pp.167-175
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• 2001

Semiconductor diode detectors coated with neutron reactive material are presently under investigation for various uses, such as remote sensing of thermal neutrons, fast neutron counting, and thermal neutron radiography. Theory indicates that single-coated devices can yield thermal neutron efficiencies from 4% to 11 %, which is supported by experimental evidence. Radiation endurance measurements indicate that the devices function well up to a limiting thermal neutron fluence of $10^{13}/cm^2$, beyond which noticeable degradation occurs. Thermal neutron contrast images of step wedges and simple phantoms, taken with dual in-line pixel devices, show promise for thermal neutron imaging detectors.

• 시큐리티연구
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• 제58호
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• pp.9-34
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• 2019

경찰은 헌법상 권리인 집회의 자유를 보장해야 하며, 동시에 이러한 권리행사에 있어서 야기될 수 있는 과도한 무질서와 불편 역시 예방하고 억제해야 하는 이중적인 책무를 부여받고 있다. 경찰은 집회 참가자에 대한 안전관리 목적 차원에서 집회시위 참가인원을 추산하고 있으며, 그 추산방식은 기본적으로 단위면적당 인구밀도 값을 통하여 "특정시점 최대 인원"을 집계하는 방식이다. 이와 대조적으로, 집회시위 주최자는 집회시위 참가인원의 숫자(규모) 자체가 집회의 성공여부로 연결되는 만큼 전체 집회에 잠깐이라도 참여한 사람까지 모두 포함하는, 다시 말해서 누적인원을 계산하는 이른바 "연인원 집계방식"을 사용하고 있다. 집계방식의 목적과 세부 방법론의 차이로 인한 추산결과의 격차는 당연한 결과임에도 불구하고, 경찰은 고의적으로 추산인원을 축소하다는 비판에 직면하자 현재는 추산결과 자체를 공개하지 않고 있다. 집회시위 추산방식에 대한 상당한 논쟁과 이슈에도 불구하고, 관련 국내 선행연구는 극소수에 불과한 것으로 확인되었다. 이마저도 경찰의 특정시점 최대인원 집계방식과 집회시위 주최자의 연인원 집계방식의 장단점을 도출하고 비교하는 정도에 그치고 있었고, 아쉽게 국외의 학술논문이나 연구에 대한 분석 부분은 전혀 찾아볼 수 없었다. 이에 본 학술논문은 "외국에서는 집회시위 인원 추산방식에 대한 어떠한 연구가 존재할까? 특정시점 최대인원방식과 연인원 누적 집계방식 외에 다른 세부 방법론은 존재하지 않는 것일까? 만약 존재한다고 한다면, 어떠한 세부 방법론이 제시되어 있을까?"라는 연구문제를 도출하였고, 이에 대한 해답을 찾기 위하여 참가인원 추산방법에 대한 해외 학술논문 및 연구결과를 분석해보았다. 이러한 분석을 바탕으로, 본 연구에서는 해외에서 연구된 참가인원 추산방식을 크게 ① 단위면적당 인구밀도 활용모델, ② 행진인원 추산모델, ③ 전자기술기반 이미지 비활용 추산모델 등, 세 가지 모델로 분류해보았고, 나아가 각각의 모델에 속하는 세부 연구결과도 요약·제시해보았다. 이를 통하여 마지막으로, 우리의 집회시위 참가인원 추산방식에 대한 개괄적인 정책 시사점 내지 향후 추진되어야 할 연구 방향성도 도출하고자 하였다.

• 한국양봉학회지
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• 제34권1호
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• pp.47-55
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• 2019

다양한 농업 생산 분야에서 정보통신기술 (ICT, Information and Communications Technologies)이 융합하여 많은 발전을 이루어내고 있다. 꿀벌의 활동과 관련한 온·습도, 음파, 이산화탄소, 암모니아, 황화수소 등 다양한 봉군내·외의 요인들과 꿀벌의 활동 추적에 대한 ICT 융복합 시스템 개발연구가 최근 이슈화되고 있다. 본 연구에서는 이중 적외선 센서(QRE1113)를 이용하여 꿀벌 출입 자동 모니터링 시스템을 구현하여 실측 자료를 비교·분석하였다. 꿀벌의 방화행동을 연구하는 기존의 밀원식물 방화 개체 수 측정, 영상촬영을 통한 출입 활동 수 수동 분석, 해외 다양한 자동모니터링 시스템들과 비교하여 본 시스템은 모니터링 시간과 노력의 단축 및 외부 방화 활동과의 일치성, 수동 분석과 상대 오차 5% 미만으로 높은 실효성을 보였다. 또한, 저전력블루투스(BLE)모듈을 활용한 내·외부 온도 센서와 병행을 통해 시스템의 확장성을 확보하였으며, 이 시스템으로부터 확보한 한달간의 데이터 분석을 통해 온도와 방화행동 간 상관관계 분석 및 하루 평균 손실되는 꿀벌의 개체수(출역봉의 1.88%)를 측정할 수 있었다. 향후 복합적인 모니터링 시스템 확장과 빅데이터 축적을 통해 더욱 강력한 실시간 모니터링 도구 및 꿀벌 생태 교육자료로 양봉 산업 발전에 크게 기여할 수 있고, 과학적 분석 도구로 활용될 것이다.