• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.4
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• pp.567-571
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• 2005

In this study, the effects of varying the amount of water, soaking time at $25^{\circ}C$ and drying time after soaking at $45^{\circ}C$ on the induction of resveratrol were evaluated to optimize the soaking treatment by response surface methodology (RSM). After response surface regression (RSREG), the second-order polynomial equation was fitted to the experimental data. The analysis of variance showed that the model appeared to be adequate $(R^2=0.9547)$ with no significant lack of fit (p>0.1). From statistical analysis, amount of water and soaking time were found to be significant factors. On the other hand, drying time was not significant. Ridge analysis showed that the optimized parameters were $67.15\%$ for amount of water, 19.58 hr for soaking time, 65.56 hr for drying time. It was confirmed that resveratrol content was increased from $0.1\;{\mu}g/g$ to $4.55\;{\mu}g/g$ under the optimized conditions. In addition, the experimental values at the optimized condition agreed with values predicted by ridge analysis. The analytical method validation parameters such as accuracy, precision, and specificity were calculated to ensure the method's validity.

• Journal of the Korean Society for Railway
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• v.17 no.4
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• pp.270-280
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• 2014

In this study, to examine the causes of cracks in continuously reinforced concrete tracks (CRCTs) and the main factors affecting cracking, a field survey on the status of cracks and crack patterns in the Gyeong-bu high speed line was conducted, and the crack patterns of CRCT due to the temperature difference between the top of the slab (TCL) and the bottom of the subbase (HSB) and the drying shrinkage of concrete were predicted by a nonlinear finite element model considering the structure of CRCT. The results of the numerical analysis show that cracks will be developed at the interface between the sleeper and the TCL, and under the sleeper due to the temperature difference and concrete shrinkage. This corresponds well to the crack locations found in the field. Also, it is found that the most significant factors are the coefficient of thermal expansion with respect to the temperature difference, and the drying shrinkage strain with respect to shrinkage. According to the results, the reinforcement ratio should be carefully determined considering the structures of CRCT because the crack spacing is not always proportional to the reinforcement ratio due to the sleepers embedded in the TCL.

• Korean Journal of Food Science and Technology
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• v.41 no.1
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• pp.27-31
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• 2009

Top spray-drying method is frequently utilized for flavor encapsulation, but the top spray-dried products frequently suffer from high losses of volatile flavor as the result of a high processing temperature (150-$300^{\circ}C$). In an effort to solve these problems, a low-temperature fluidized-bed granulating method was utilized to encapsulate the flavor. For the encapsulation of sesame oil, oil-in-water emulsions of sesame oil and a mixture of maltodextrin, modified starch, gum arabic, and gellan gum were bottom-sprayed at milder temperatures (70-$100^{\circ}C$) using a fluidized-bed granulator. Sesame oil extracts from microcapsules were obtained via a simultaneous distillation/extraction technique, and the retention of volatile flavor compounds was analyzed via a gas chromatography-mass spectrometry. The retention of volatile flavors of sesame oil per se, spray-dried and fluidized-bed granulated microcapsules after 3-day-storage at $37^{\circ}C$ were 0.8%, 37.2%, and 42.0%, respectively. In addition, the low-temperature fluidized-bed granulation showed higher encapsulation yield and sensory preferences for the application of commercial products (beef rice porridge), as compared to spray drying.

• Polymer(Korea)
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• v.35 no.4
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• pp.277-283
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• 2011

Solid dispersion is mainly used for improved dissolution of poorly water-soluble drugs. Solid dispersion of pranlukast was prepared by spray-drying with plasdone S-630. When pH of water was high, pranlukast was highly soluble in the solubility experiment of solid dispersions with varying pH. The particle size of pranlukast particles in solid dispersions was measured to be in nanometers scale based on particle size analysis. Zeta-potential analysis confirmed the negative charge of solid dispersion. SEM was used to observe the surface of solid dispersion, which confirmed spherical morphology, DSC and XRD confirmed the amorphous nature of solid dispersions. The in vitro test was carried out to find improved dissolution rate of pranlukast solid dispersion in simulated juice gastric and a controlled experiment was carried out to compare pranlukast solid dispersions with a conventional drug (Onon$^{(R)}$), These results showed the dissolution properties of pranlukast solid dispersions prepared by spray drying proper for the oral pharmaceutical formulation.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.2
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• pp.204-213
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• 2000

This study deals with jet impingement, which is extensively used in the process industries to achieve intense heating, cooling or drying rates and also widely employed as a test flow for turbulent models due to its complex flow configuration, on a flat plate by numerical methods. In this calculation, the finite volume method was employed to solve the Navier-stokes equation based on the non-orthogonal coordinate with non-staggered variable arrangement. To get a better understanding for the fluid flow and heat transfer characteristics of the turbulent jet impingements, $k-{\varepsilon}-{\overline{v^{'2}}}$ turbulent model was adapted and compared with the experimental data and the result of standard $k-{\varepsilon}$ turbulent model. Numerical calculations were carried out with various flow rates, nozzle to plate distances. In the case of the axisymmetric jet impingement on a flat plate, $k-{\varepsilon}-{\overline{v^{'2}}}$ turbulent model showed better agreement with the experimental data than the standard $k-{\varepsilon}$ turbulent model in the prediction of the mean velocity profiles, the turbulent velocity profiles. the turbulent shear stress and the heat transfer rate. The highest heat transfer rate can be obtained when the impingement occurs within the potential core..

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.10
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• pp.1720-1725
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• 2004

Absorption characteristics of green tea powder were investigated. The monolayer moisture content determined by GAB equation was 0.024~0.052 g $H_2O$/g dry solid. The absorption enthalpy was calculated with different particle size and various water activities. It showed that the absorption energy was decreased with increasing water activity but no difference was found on particle size increasement. Among models applied for predicting equilibrium moisture content, Halsey model was the best fit model for green tea powders, showing the lowest prediction deviation of 2.1~4.0%. The prediction model equations for the water activity was established as function of relative humidity, time and temperature. The model equation will be helpful for future work on drying and storage of green tea powder.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.9 no.1
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• pp.1-8
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• 1997

A horizontal 2-D model which includes the wetting-drying treatment technique in the intertidal zone is established for the prediction of tidal changes and contaminant transport due to the development of Incheon coastal zone. The flow model is verified by the measurement data at Jeong-Do, and then the computed values are closely matched to the observed water elevations and velocities of main-flow direction. And then, the tidal change patterns are simulated using this model before and after the construction of the Youngjongdo New Airport and Shihwa Seadike. In the spring tide condition, pollutants transport pattern is also simulated for the arbitrary pollutants loads. By the analysis of this numerical simulation results, the velocities after development are decreased, and discharged pollutants are mainly transported by the advection along a narrow deep trough. Thus, this model can be used as the compatible prediction model for the tidal change and pollutant transport due to the development plan of Incheon coastal zone.

• Korean Journal of Veterinary Research
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• v.56 no.3
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• pp.155-160
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• 2016

This study was conducted to evaluate three different mixed formulations of sodium hyaluronate (SH) and carboxymethyl cellulose (CMC) using a low-humidity air flow-induced rat dry eye model and determine the most suitable mixture. The total thickness of the cornea, corneal epithelial thickness, corneal stroma thickness, damaged corneal epithelium percentage region, thickness of the bulbar conjunctiva epithelium, number of goblet cells, goblet cell occupation percentage region, and damaged bulbar conjunctiva epithelium percentage region were measured by histomorphological evaluation. After 5 h exposure to drying airflow, the thickness of the cornea and conjunctiva was decreased with desquamation of the corneal and conjunctiva epithelium. However, these dry eye symptoms were markedly inhibited by treatment with the reference and test formulations. More favorable effects on decreased thickness were detected in response to the CMC than the SH. However, SH had a greater protective effect against corneal and conjunctiva epithelial damage. The application of a mixture of 0.1% SH and 0.2% CMC showed more favorable effects on the corneal and conjunctival damage and the stabilization of the ocular surface than SH or CMC alone.

• International Journal of Highway Engineering
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• v.7 no.3 s.25
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• pp.23-30
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• 2005

Predicting distribution and variation of humidity inside concrete is essential to improve curing quality of concrete at field. The concrete humidity is predicted by numerical analysis using surface humidity as boundary condition. However, ambient humidity has been used instead of the surface humidity because the surface humidity could not be ccurately measured. Because it is hard to accurately measure the surface humidity, owever, the ambient humidity has been used instead of the surface humidity in the numerical analysis. In this paper, a methodology to accurately measure the surface humidity is suggested, and the ambient humidity and the humidity at the surface and inside the concrete measured by a series of laboratory tests are presented. The cause of low concrete humidity immediately after placement was investigated by a separately performed test. A surface humidity prediction model was developed using the measured humidity, and consequently validated through an additional test.

• Journal of the Korea Institute of Building Construction
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• v.7 no.3
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• pp.123-130
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• 2007

This study investigated the fundamental properties and shrinkage properties of high performance concrete with water/binder ratio of 0, 30 and with combination of expansive additive and shrinkage reducing agent. According to the results, the fluidity of high performance concrete showed lower the using method in combination with expansive additive and shrinkage reducing agent than the separately using method of that, so the amount of superplasticizer increased when the adding ratio of expansive additive and shrinkage reducing agent increased. However the air content of concrete increased when used in combination with expansive additive and shrinkage reducing agent, so the amount of AE agent decreased. The compressive strength showed the highest at 5% of expansive additive, and decreased with an increase of the amount of shrinkage reducing agent. Furthermore, in order to reduce the shrinkage of high performance concrete, it was found that the using method in combination with expansive additive and shrinkage reducing agent was more effective than separately using method of that. Autogenous shrinkage was predicted using JCI model. Because JCI model is unable to consider the effect of EA and SRA, correction factor should be added to enhance the accuracy.