• Journal of Korean Ophthalmic Optics Society
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• v.9 no.2
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• pp.333-343
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• 2004

Impression cytology refers to application of cellulose acetate filter material to the ocular surface to remove the superficial layers of the conjunctival epithelium. The technique is non-invasive, is easy to perform, causes minimal discomfort to the patient, and can be used to follow changes in the conjunctival ocular surface over time. With this method, the morphology of the conjunctival ocular surface can be studied and the degree of squmaous metaplasia assessed. This study was performed to evaluate the conjunctival surface by impression cytology in dry eye patients. A total of 70 students with no contact lens wearing history were recruited. Subjects were required to fill in a McMonnies dry eye symptom questionnaire. The non-invasive tear thinning time(TIT) test of each subject was measured, followed by Schirmer tear test(STI), tear film break-up time(TBUT) tests and Rose-bengal staining were performed as a baseline. Conjunctival epithelial cells from the inferior bulbar conjunctiva were harvested by the impression cytology technique. The specimens collected were labelled and stained with PAS(Periodic Acid Schift)-haematoxylin. The goblet cells and conjunctival epithelial cells were observed under a light microscope of 400x magnification. The specimens were classified according to the Nelson Grading scale which was based on the degree of squamous metaplasia such as changes of goblet cells density, size/form, N:C(nucleus : cytoplasm) ratio. Dry eye patients were observed morphological changes of the epithelial cells, different nuclear alterations, decrease of the goblet cells density. The degree of cytological changes was related to severity of dry eye conditions. When the epithelial cell morphology was graded according to the system described by Nelson, specimens from the control group revealed 91.43% of the eyes to be grade 0 and 8.57% to be grade 1, whereas of the dry eye patients, 20% were grade 0, 42.86% grade 1, 34.29% grade 2 and 2,86% grade 3. Impression cytology represents a non- or minimally invasive biopsy of the ocular surface epithelium with no side effects or contraindications. It has demonstrated to be a useful diagnostic aid for a wide variety of processes involving the ocular surface. This technique is a safe, simple method and may help increase understanding of various ocular surface alterations in dry eye patients.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.2
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• pp.27-30
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• 2009

Purpose: Transmittance at UV-visible spectra range was measured to confirm the effect of wet/dry state of commercially available SCL on human eyes. Method: Commercially available five SCLs fabricated by different materials were selected to measure optical properties according to humidity. Results: A relatively high transmittance above about 80% in the visible spectra range of the SCLs were observed. In the UV spectra range, the wet samples showed higher transmittance than those dried except an unusual case. Conclusions: All the samples having a high optical properties in the visible spectra range exhibit a high transmittance in the UV region. Further research will be needed to develop new materials having a sharp absorption edge in the UV spectra range.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.602-608
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• 2004

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia which results from one or both of decreased insulin secretion and increased insulin resistance. Chronic hyperglycemia causes damage to the eyes, kidneys, nerves, heart and blood vessels. The major goal in treating diabetes mellitus is controlling elevated blood sugars without causing abnormally low levels of blood sugar. A 67-year-old woman was admitted with hyperglycemia, thirst, Lt. leg numbness and both leg weakness. The patient was diagnosed as So-gal(消渴) due to dry ness-heat based on yin-deficiency(陰虛燥熱) through oriental medicine and NIDDM through western medicine. The patient was treated with oriental and western medicines. Specifically herbal medicine(Gamijihwangtang), acupuncture, moxa theraphy were used as well as oral medications. Clinical symptoms improved and hyperglycemia dramatically stablized.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.7 no.2
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• pp.51-56
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• 2001

The purpose of this study is to make a new diagnostic test model for the physical disturbance signs for the overuser or addiction persons in internet. Variations of Somato-diagnostic testR for Internet Addiction Syndrome(Park V1.0) are follows ; 1. Are you hurt in your elbow or shoulder? 2. Do you feel stiffness in your neck? 3. Do you feel numbness of wrist on drive? 4. Are you hurt in your fingers on touch a keyboard or mouse? 5. Are you hurt in your back? 6. I feel taut on my legs sometimes. 7. I feel dim or bloodshot in my eyes. 8. I feel dry in my eyeball. 9. I feel heavy and ache on my head. 10. I can't sleep very well. 11. I have a digestive upset often. 12. My hand's full with sweat on computing. 13. I feel tremble or heavy in my heart. 14. I'm tired easily. 15. I'm not concerned about a sex impulse at all.

• YAKHAK HOEJI
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• v.57 no.2
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• pp.139-149
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• 2013

Glaucoma is a potentially blinding chronic disease requiring life-long commitment to medical therapy. Failure to adhere to anti-glaucoma treatment may lead to disease progression and visual loss. This study surveyed the adherence to glaucoma eye drop and eye drop instillation technique of glaucoma patients and analyzed the improvement of the adherence and installation technique after patient education for eye drop instillation instructions. Collected responses were statistically analyzed using Kruskal-Wallis test, Mann-Whitney test, Chi-square test, Fisher's exact test, Spearman's correlation coefficient, or one sample proportion test. The survey after patient education for proper eye drop instillation revealed that, even if the patients experienced the adverse effect of their eyes getting dry, they used the eye drop more regularly. They were better at instillation techniques like putting the eye drop inside the eye, and also avoiding applying too much medication or touching their eye with the eye drop bottle. Also, when the patients were divided into groups based on etiologic division, there was difference among groups regarding which category they answered has improved. The result showed improvement in adherence to glaucoma eye drop and eye drop instillation technique after patient education, implicating that patient education is an important aspect of eye care for glaucoma patient and helps them participate in the proper management.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.2
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• pp.49-60
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• 2012

Objective : Acupuncture has been used for treating eye disease for thousands of years but there are few evidence based medicine (EBM) for its use. This study is a review of Clinical trials related to the treatment of eye disease by acupuncture therapy. Methods : We referred a Pubmed site by using searching word of "eye, acupuncture" (Limits: 10 Year, Clinical Trials, Humans, English). Results : Eight journals with twelve papers were searched. Eight of these studies were randomized and ten trials of acupuncture treatments reported significant effect. On the topic of these clinical trials, five of them were about dry eyes, four about disorder of refraction, two about intraocular pressure and one about visual function. The result of clinical studies represented the significant cure rate. Conclusion : We found that RCTs about the acupucnture for eye diseases were more and more published. But their average impact factor was 2.16 and average modified Jadad score was 3.89, so there needs more qualifying studies.

• The Journal of the Society of Stroke on Korean Medicine
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• v.17 no.1
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• pp.39-44
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• 2016

■ Objectives A case of a 44 years old Korean female with left side headache due to Transformed migraine is presented. ■ Methods He was treated with electroacupuncture around eyes and dry cupping on shoulder, moxibustion, acupuncture and herbal medicine, Chai Ling Tang. Then we evaluated the improvement by Pain area comparison and Numerical Rating Scale(NRS). ■ Results Headache was improved after the administration of Korean medical treatments. ■ Conclusion Korean medical treatment may be effective in treating headache due to Transformed migraine.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1368-1373
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• 2008

This study was done to calculate the specific indicators of Fire-Heat Pattern Identification and Yin Deficiency Pattern Identification settled by tentative Korean Standard Differentiation of the Symptoms and Signs for Stroke. The subjects were 764 hospitalized patients with stroke, and a list of registry was made for each of them. Frequency and Correlations among Fire-Heat and Yin Deficiency indicators were studied. Fire-Heat pattern group included 175 patients out of 764, Yin Deficiency pattern group included 103 patients out of 764. Among the indicators of Fire-Heat pattern, those, in order of highest frequency, were 'heat vexation and aversion to heat', 'reddened complexion', 'thirst'. Among the indicators of Yin Deficiency pattern, those, in order of highest frequency, were 'dry mouth', 'red tongue', 'fine and rapid pulse'. Among the Fire-Heat pattern indicators, 'yellow fur' and 'thirst', 'heat vexation in the chest' and 'vexation and insomnia' showed most significant correlation. Among the Yin Deficiency pattern indicators, 'aphtha or tongue sore' and 'heat in the palms and soles', 'red tongue' and 'dry fur' showed most significant correlation. 'Reddened complexion', 'dry eyes', 'surging and parid pulse', 'heat vexation and aversion to heat' are classify between Fire-Heat pattern and Yin Deficiency pattern. 'Surging and parid pulse', 'Reddened complexion' are mostly representative of Fire-Heat pattern and 'fine and rapid pulse' are mostly representative of Yin Deficiency pattern.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.2
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• pp.201-207
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• 2011

Purpose: This study was to find out the influence on eyes of indoor air quality in college students taking course, such as Sick-building syndrome symptoms and effects on the eye in new-built university buildings. Methods: We selected a new building in a university located in Metro Seoul and college students in a department for the study. The number of total participants was 33, to whom questionnaire surveys were conducted in advance to check individual traits (gender, age, whether to smoke, whether to wear contact lenses, or whether to drink). The first questionnaire surveys and checking of ocular symptoms to first indoor hazardous materials were conducted in October and two months later the second surveys and checking were carried out in December. The indoor air quality was measured when conducting the first questionnaire surveys and the second questionnaire surveys; especially measurements of gaseous materials such as aldehydes and VOCs in the indoor air were conducted. Results: Indoor air quality of the new building was as follows: formaldehyde level was 22.90 ${\mu}g/m^3$ in the first measurement and 16.79 ${\mu}g/m^3$ in the second measurement. In addition, most materials showed higher value in the first measurement. The level of TVOC was statistically significant (p<0.05) decreased on 448.54 ${\mu}g/m^3$ in the first and 62.55 ${\mu}g/m^3$ in the second. In clinical assessments to check ocular symptoms caused by eye irritations, dry eye syndrome was found in the first and second exposures. When comparing the first and second assessments, dry eyes deteriorated in the morning of the second attempt compared to the first one. Conclusions: In the survey of ocular symptoms and the measurement of indoor air quality, the level of formaldehyde was measured higher in the second attempt than the first; thus, it was confirmed the influence of indoor air quality in a new building upon ocular symptoms of occupants.

• Journal of Yeungnam Medical Science
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• v.15 no.2
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• pp.325-340
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• 1998

A cross-sectional study was conducted to evaluate the relationship between sick building syndrome(SBS) and the environmental factors affecting SBS on 130 underground workers and 60 controls. The study consisted of 1) a review of environmental condition 2) measurement of temperature, $O_2$, $CO_2$, CO, and formaldehyde and 3) a questionnaire survey of symptom prevalence and perception of environmental conditions using indoor Air Quality questionnaire recommended by National Institute for Occupational Safety and Health. Bronchitis and dust allergy were more prevalent in underground workers significantly(p < 0.05). Among the 18 symptoms related to the indoor air pollution, the experience rate of dry, itching or irritated eyes, sore or dry throat, chest tightness, tired or strained eyes and dry or itchy skin symptom was significantly different between the underground workers and controls. The diagnostic criteria of SBS was defined as at least 1 symptom is experienced 1-3 times a week during the last 1 month among 18 indoor air pollution related symptoms which can be relieved by moving out of the underground. Applying the criteria, the mean symptom score was significant higher in underground workers than controls significantly (p < 0.05). These resalts indicated that underground workers are under inappropriate ergonomic and physical condition and inadequate ventilation. Their experience rate of symptoms related to indoor air pollution and prevalence of SBS was significantly higher than controls. To reduce the prevalence of SBS of underground workers, the surveillance system of indoor air quality, restriction of using fuel in underground and legislative regulations for the environment are needed to establish a better indoor air quality. Early detection, treatment and prevention of SBS through medical attention is also needed.