• Title/Summary/Keyword: Drug education

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Study on Perception of Weight Control and Patterns of Diet/Low-Calorie Food Consumption according to Weight Status in Adult Women (성인여성의 체중상태에 따른 체중조절인식과 다이어트 식품 구매·섭취행동에 관한 연구)

  • Han, Chae-Jeong
    • Journal of the East Asian Society of Dietary Life
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    • v.27 no.2
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    • pp.104-113
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    • 2017
  • The purpose of this study was to analyze and consumption patterns diet/low-calorie food. Ubjects were 353 adult women aged 20s~50s. Ubjects were divided into three groups according to body mass index (BMI): Normal group (BMI>23.0), overweight group (23.0${\leq}$BMI<25.0), and obesity group (BMI${\geq}$25.0). This study collected all information by self-administrated questionnaires. The SPSS version 21.0 was used for analysis of data. The obesity group lower education level (p<0.001), higher age (p<0.001) and higher income (p<0.001) than normal group. However, score of health status was highest in normal group (p<0.001). Proportion of obesity group pill type diet/low-calorie (p<0.034), drug (diuretic, appetite suppressant and riental medicine) (p<0.001), and cosmetic surgery (p<0.001). The main reason for consumption of diet/low-calorie was control without starving (28.0%). Obese group emphasized manufacturer, ingredient and reputation, whereas the normal group emphasized price and expected effectiveness (p<0.001).

Autonomy Level of Nurse according to Nursing Delivery System (간호 분담체계에 따른 간호사의 자율성 정도)

  • Oh, Eun Sil
    • Korean Journal of Occupational Health Nursing
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    • v.9 no.2
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    • pp.155-165
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    • 2000
  • This study is to grope for a plan to increase nurse's autonomy by grasping autonomy degree according to nursing delivery system. The subject of this study are 265 nurses who work for 4 general hospitals in Seoul, and 73 of them work in primary nursing delivery system, 99 of them in team nursing delivery system and 93 of them in functional nursing delivery system. Data collection was done through questionaires from Sep. 1, 1997 to Sep. 30, 1997, and autonomy was measured by Professional Nursing Autonomy Scale developed by Schutzonhofer. Data analysis as inspected with $X^2$ test, ANOVA, and t-test, using SPSS program. The results are as follows : 1. When it comes to the autonomy of all the nurses, mean score was 161.99. Which is medium level, and autonomy degree according to nursing delivery system had no significant differences. 2. There was a significant difference in autonomy degree according to inservice education among the subject's work-related characteristics, and there was no significant difference in autonomy distribution in each grade according to general characteristics although older group, married group, and junior college graduates group showed rather higher trends. 3. Considering each item, questions related to direct nursing such as "Vital sign monitoring", "Nursing rounding", "Withhold contraindicated drug", showed high score in autonomy scores, and long-term and indirect nursing behaviors such as "Nursing administration", "Nursing research", "Follow-up care" and "Educational planning".

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Parents' Perception and Behaviors regarding Child Safety Accidents (아동의 안전사고에 대한 부모의 인식 및 행동)

  • Kim, Shin-Jeong;Lee, Jung Min;Min, Ji young
    • Child Health Nursing Research
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    • v.23 no.1
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    • pp.91-100
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    • 2017
  • Purpose: The purpose of this study was to investigate parents' perception and behaviors in the case of a child safety accident. Methods: The participants were 254 parents of children under 12 years old. Data were collected from October 12 to November 25, 2016 using self-report questionnaire. Results: The mean score for parental perception and behaviors showed a high score of $3.12{\pm}0.30$. In addition, the top three categories were drug management ($3.45{\pm}0.54$), prevention of burns ($3.34{\pm}0.52$), and vehicle safety ($3.34{\pm}0.44$). The overall difference in categories of perception and behaviors about child safety accidents according to demographic characteristics of participants, was developmental age (F=5.616, p=.004). Most of the categories had significant correlation with other categories. Conclusion: Findings in this study show parental perception and behaviors were relatively high. It is recommended that safety education for parents should be done for a healthy life for their children.

Garcinexanthone G, a Selective Butyrylcholinesterase Inhibitor from the Stem Bark of Garcinia atroviridis

  • Khaw, Kooi-Yeong;Murugaiyah, Vikneswaran;Khairuddean, Melati;Tan, Wen-Nee
    • Natural Product Sciences
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    • v.24 no.2
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    • pp.88-92
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    • 2018
  • The present study was undertaken to investigate the isolated compounds from the stem bark of Garcinia atroviridis as potential cholinesterase inhibitors and the ligand-enzyme interactions of selected bioactive compounds in silico. The in vitro cholinesterase results showed that quercetin (3) was the most active AChE inhibitor ($12.65{\pm}1.57{\mu}g/ml$) while garcinexanthone G (6) was the most active BChE inhibitor ($18.86{\pm}2.41{\mu}g/ml$). It is noteworthy to note that compound 6 was a selective inhibitor with the selectivity index of 11.82. Molecular insight from docking interaction further substantiate that orientation of compound 6 in the catalytic site which enhanced its binding affinity as compared to other xanthones. The nature of protein-ligand interactions of compound 6 is mainly hydrogen bonding, and the hydroxyl group of compound 6 at C-10 is vital in BChE inhibition activity. Therefore, compound 6 is a notable lead for further drug design and development of BChE selective inhibitor.

The Perceived Importance and Performance Frequency of Nursing Interventions in the Oncology Units in a Tertiary Hospital (종양내과병동에서의 간호중재 중요도 및 수행 빈도에 관한 연구 - 일 종합요양 전문기관을 중심으로 -)

  • Kwon, In Gak;Cho, Myung Sook;Shin, Hee Yeon
    • Korean Journal of Adult Nursing
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    • v.19 no.2
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    • pp.260-273
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    • 2007
  • Purpose: This study was performed to understand the perceived importance and performance frequencies of nursing interventions and identify the core and major interventions in oncology units. Methods: Questionnaires using 151 nursing interventions were given to 45 nurses. The performance frequency was measured through the database of the nursing process recording system for 1 year. Results: The perceived importance of the nursing interventions averaged out to be 3.5 among 4 and on average 36.5 times of nursing interventions were performed on each patient. Fifteen core nursing interventions including 'pain management' were identified and they made up 82.7% of the entire performance frequency rate. And 26 interventions including 'drug administration: Amphotericin-B' were identified as major nursing interventions and occupied 10.6% of the entire performance frequency rate. Conclusion: Since the core and the major nursing interventions were identified and these occupied 93.3% of the all nursing interventions, these results can be utilized as baseline data for establishing the guidelines and standards of nursing interventions and providing systematic education for oncology nurses in Korea.

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Maternal Factors and Risk of Childhood Leukemia

  • Kumar, Ashok;Vashist, Minakshi;Rathee, Radha
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.781-784
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    • 2014
  • Background: Although the cause in most cases of childhood leukemia is not known, the contribution of environmental risk factors in the context of genetic predisposition has been reported with inconsistent results. The aim of this study was to examine association of childhood leukemia with maternal factors especially during pregnancy, to help in avoiding risk factors. Materials and Methods: This case-control study included children younger than 18 years diagnosed with leukemia from 2008 to 2012. Controls were randomly selected and individually matched to cases with respect to age, sex, and residency. All variables were compared between cases and control to determine any significant association with leukemia. Results: Statistically significant associations between risk of childhood leukemia with mother's education (p=0.001), occupation (p=0.0005) and pesticides exposure (p=0.005) during pregnancy were found. However, there were no significant links with maternal age (p=0.090), history of fetal loss (0.85), history of radiography during pregnancy (p=0.400), history of drug intake (p=0.689) and infection (p=0.696) during pregnancy. Conclusions: The results showed increased risk of leukemia in children whose mothers were working in agriculture and were exposed to pesticides during pregnancy. The further study needs to be investigated to know association of various maternal risk factors with leukemia which remained unknown in this study.

Study for Serum Cholesterol Level with Patients on Premature Examination of Stroke - Based on National Cholesterol Education Program Adult Treatment Panel III - (중풍 조기검진 환자의 혈중지질에 대한 연구 - NCEP Adult Treatment Panel III를 중심으로 -)

  • Chang, Mun-Won;Choi, Seong-Hwan;Jo, Hyun-Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.4
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    • pp.716-721
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    • 2010
  • The aim of this study is to investigate the serum cholesterol level of patients who visited Oriental Hospital of Daejeon University to predict stroke, in Korea. In the time of period June 15th 2009 to June 20th 2009, 45 patients visited Oriental Hospital of Daejeon University to check the risk of stroke. We checked their blood to find out the serum cholesterol level and investigated their past history according to Adult Treatment Panel III guidelines. Male has higher risk of coronary heart disease than the female. The average of the total serum cholesterol of the participants was lower than the average of Korean. The percentage of the participants who have less HDL-cholesterol than 40 mg/dL was 33.3% and this result is less than the average percentage of Korean. Only 8.9% of the participants were placed in group who need to use lipid-lowering drug to reduce the lipoprotein density. Checking the characters of the person is necessary to use lipid-lowering drugs. This study can be the baseline data of actual condition of serum cholesterol level.

Intestinal Hypoganglionosis Leading to Intestinal Failure and the Compassionate Use of OmegavenTM

  • Khalaf, Racha;Karjoo, Sara;Danielson, Paul;Wilsey, Michael;Shakeel, Fauzia
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.20 no.1
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    • pp.55-60
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    • 2017
  • Intestinal hypoganglionosis is a rare innervation disorder that provides numerous nutritional, medical and surgical challenges. In this case report, we present a case of a newborn with intestinal hypoganglionosis leading to intestinal failure and intestinal failure-associated liver disease who responded to $Omegaven^{TM}$, a fat emulsion comprised of omega-3 fatty acids. $Omegaven^{TM}$ has been shown to be beneficial in the management of cholestatic liver injury. Clinical success with $Omegaven^{TM}$ was seen in this patient with a clear decrease in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and complete resolution of cholestasis with a direct bilirubin of zero within two weeks of initiation of $Omegaven^{TM}$. No current guidelines for the diagnosis and management of hypoganglionosis are available. We recommend a multidisciplinary approach and the use of novel therapies such as fat emulsions composed of omega-3 fatty acids for improved patient outcomes. Appropriate compassionate use protocols should be obtained from the Food and Drug Administration prior to initiation of $Omegaven^{TM}$.

Effects of Spinal-Z in Patients with Gastroesophageal Cancer

  • Panahi, Yunes;Saadat, Alireza;Seifi, Maghsoud;Rajaee, Mahdi;Butler, Alexandra E.;Sahebkar, Amirhossein
    • Journal of Pharmacopuncture
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    • v.21 no.1
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    • pp.26-34
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    • 2018
  • Objective: The purpose of this study was to investigate the efficacy and safety of spinal-Z, derived from Peganum harmala seeds and Dracocephalum Kotschyi Boiss leaves, in patients with esophageal and stomach adenocarcinoma, and squamous cell carcinoma of the esophagus. Methods: Sixty-one patients with malignancies of the upper gastrointestinal tract were randomly assigned to one of two groups (treatment or control) in a double-blind fashion. Six capsules of Spinal-Z were prescribed to the patients with the regimen of 600 mg/m2/day, and placebo to the control group, for six months. Results: There were no significant differences between the two groups with regard to age, sex, duration of cancer, type of cancer and family history of cancer. There were significant differences in abdominal pain, heartburn, constipation and vomiting between the two groups, following spinal-Z therapy. Evaluation of drug side effects showed no difference in cough or other respiratory symptoms, itching, headache or dizziness between the two groups, both before and after treatment. Conclusion: This study indicates that Spinal-Z is safe and efficacious in the management of patients with upper gastrointestinal tract cancers.

Methodological research of obese children focused on the recent clinical researches (최근 임상연구를 중심으로 한 소아비만에 관한 방법론적 연구)

  • Lee, Hyun-Sook;Kim, Jang-Hyun
    • The Journal of Pediatrics of Korean Medicine
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    • v.21 no.1
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    • pp.11-26
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    • 2007
  • Objectives : The purpose of this study is to investigate the recent tendency of clinical researches of obese children for finding better oriental medicine treatments. Methods : This study was focused on diagnoses, treatments, prognoses and cures of obese children based on 37 of other papers which are J Korean Oriental Med, J Korean Oriental Pediatrics, J Korean Acd Fam Med, J Korean society for the study of obesity, Korea Sport Research, J Korean Academy of Pediatric Allergy and Respiratory Disease, J Korean Society for Health Education and Promotion, Korean J Pediatric, and Korean J Oriental Physiology and Pathology. Results : The rate of obese children has been increased continuously. There are several reasons for increased rate : For example, inadequate eating habit, lack of exercise, and genetic factors such as inherited diseases, and the disorder of the endocrine system. The obesity in childhood or adolescent can cause not only the physical problems but also the mental problems. It is necessary for children to diet, change life style, exercise continuously, and being active in order to prevent child obesity and keep healthy. Obesity can be treated through therapy diet, exercise, behavior modification, drug therapy and operation. Conclusion : It is important to recognize the children obesity, and make better treatments for that in the way of oriental cure. Moreover, additional reports should be keeping up based on continuing clinical researches.

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