• 제목/요약/키워드: Drug administration

검색결과 3,432건 처리시간 0.032초

CORRELATION BETWEEN SKIN IRRITATION AND CYTOTOXICITY OF ANTI-WRINKLE AGENTS

  • Lee, Eun-Hee;Hong, Jin-Tae;Lee, Jong-Kwon;Kim,Yong-Kyu;Park, Ki-Sook;Jung, Kyoung-Mi;Kwan, Jung-Hai;Lee, Sun-Hee;Yang, Ki-Hwa;Chung, Soo-Youn
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.110-110
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    • 2001
  • To compare skin irritation and cytotoxicity of anti-wrinkle agents, we examined skin irritation of six anti-wrinkle agents (ascorbic acid, glycolic acid, all trans-retinoic acid, ginseng extract, retinol, EB) in New Zeland white rabbit.(omitted)

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15-DEOXY-${\Delta}$ 12,14-PROSTAGLANDIN J2 DECREASED ACTIVATION OF TRANSCRIPTION FACTOR $NF-{\kappa}$ B BY BETA-AMYLOID IN MUTANT PS-2 TRANSFECTED PC12 CELLS

  • Oh, Jae-Ho;Hong, Jin-Tae;Kim, Yong-Soon;Kim, Youg-Kyu;Park, Ki-Sook;Song, Chi-Won;Jung, Hai-Kwan;Park, Chang-Won;Jung, Kyung-Mi;Yang, Ki-Hwa;Chung, Soo-Youn
    • 한국환경성돌연변이발암원학회:학술대회논문집
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    • 한국환경성돌연변이발암원학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.108-108
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    • 2002
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국내 의약품 첨가제 정보체계 연구 (Survey and Classification of Pharmaceutical Excipients)

  • 박인숙;박상애;김은정;박효민;홍정희;정주연;김호정;이지현;한의식;강신정;이선희
    • Journal of Pharmaceutical Investigation
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    • 제36권4호
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    • pp.239-243
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    • 2006
  • Due to the development of new dosage forms and the improvement or pharmaceutics, the pharmaceutical excipients have become more specified and diverse, and the reclassification on them became necessary. Also with the increasing interests on the kinds and usage amount, related provisions, and evaluation of the pharmaceutical excipients, the systemic and effective control of them was in its demand. Therefore, in this research, we provided the following information on excipients: the type, amount and specification. In order to provide the information, we investigated, analysed and summarized the excipients that are approved by KFDA and published $\ulcorner$Handbook of Pharmaceutical Excipients$\lrcorner$). This handbook is expected to be used as a reference in the development of the pharmaceutics and evaluation in them. As the importance of excipients in pharmaceutics are increasing, IPEC which consist of IPEC-America, IPEC-Europe and JPEC, PDG and ICH have tried to make an international harmonization on excipient. This current status was not an exception to Korea, therefore, the result of this research is expected to make a progress in the evaluation on the excipients to an advanced level.

A NAT for reliable HBV DNA Screening of Plasma

  • Kang, Hye-Na;Noh, Hyang-Soon;Lee, Nam-Kyoung;Kim, Soon-Nam;Man, Hong-Choon;Lee, Ki-Hong;Oh, Ho-Jung;Yoo, Si-Hyung;Shin, In-Soo;Choi, Seung-Eun;Lee, Seok-Ho;Hong, Seung-Hwa
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.272.2-273
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    • 2002
  • The safety of blood and blood products is ensured by careful selection of donors. screening of donated blood and the use of validated viral inactivation and/or removal steps during the manufacture of blood products. Serologic screening procedures have substantially reduces the risk of transmission of blood-bone viruses. However, there are still residual risks despite these measures due to the inclusion of 'window period'donations. (omitted)

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Multiresidue Method of Sulfonamides in Meat by HPLC

  • Jeong, Ji-Yoon;Kim, Jung-Mi;Im, Moo-Hyeong;Choi, Dong-Mi;Park, Kun-Sang;Hong, Moo-Ki;Lee, Chul-Won
    • 한국식품위생안전성학회:학술대회논문집
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    • 한국식품위생안전성학회 2004년도 제3회 식품안전의 날 기념 학술 세미나
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    • pp.245-245
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    • 2004
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Risk assessment of endocrine disruptors in cosmetics

  • Lee, Jeong-Pyo;Choi, Sang-Sook;Son, Kyung-Hun;Yang, Seong-Jun;Kim, Shin-Ok;Paek, Ock-Jin;Cho, Hyeon-Seo;Kim, Young-Ok
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.403.3-404
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    • 2002
  • Dimethyl phthalate(DMP). diethyl phthalate(DEP), di-n-butyl phthalate (DBP). butyl benzyl phthalate(BBP). bis(2-ethylhexyl)phthalate(DEHP) and di-n-octyl phthalate(DOP) in lotions was determined by gas chromatography. and benzyl benzoate was used as the intermal standard. The separation of the six phthalates and internal standard was optimized, and the optimal analytical conditions were as follows: column. DB-1701 (I.D. 0.25mm): mobile phase. helium: oven temperature 20$0^{\circ}C$ (10 min) ${\rightarrow}10^{\circ}C$/min ${\rightarrow}260^{\circ}C$/min(30min), injector temperature 23$0^{\circ}C$, detector temperature 28$0^{\circ}C$. (omitted)

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남.북한 약전에 대한 비교조사연구 (Comparative Study of the Korean Pharmacopoeia with North Korean Pharmacopoeia)

  • 최명신;강찬순;김혜수;김은정;홍정희;고용석;김상현;장성재
    • Journal of Pharmaceutical Investigation
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    • 제34권5호
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    • pp.427-433
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    • 2004
  • With the Sunshine policy, exchange of materials and cultures inter Koreas has been broadened and expectancy of reunification is getting higher. Especially, medical supplies and medicines are one of the biggest parts in the exchange goods. So, preparing an unified official drug standard preparing new medical administration system is required. We compared the Korean pharmacopoeia with North Korean Pharmacopoeia. Two pharmacopoeias have been developed in different direction and have many differences in the nomenclature and format. In this study, we compared general notices, general rules for preparations and crude drugs, monographs, general tests, processes and apparatus.