• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.1
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• pp.145-154
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• 2006

A man visited the Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology Hospital, Dong-eui University with the dermatitis exfoliativa by drug eruption. He was suffering from the whole body itching, rubefaction, edema, scale and the feeling a chill. The drug eruption's cause assumed antibiotics. We treated a patient with Oriental Medicines(the herbal medicine of internal use and external use), aroma oils and acupuncture. After four days or so, the itching, rubefaction, edema of the skin was recovered remarkably. After one weeks or so, the scale of the skin disease was improved remarkably, we think that these are good cases to treat with Oriental Medicine, Yeongyopaedog-san. We suggest that Oriental Herb medicines have an effect with the dermatitis exfoliativa and the drug eruption.

• Journal of Korean Traditional Oncology
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• v.12 no.1
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• pp.75-82
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• 2007

Drug eruption is a cutaneous reaction caused by various drugs. It is a very common drug induced adverse reaction. Contrast media induced drug eruption is rare. But approximately 10% of people injected with contrast media experience adverse reaction, and drug eruption accounts for more than 40% of all adverse reactions. We report a case of mild drug eruption and its treatment process based on korean traditional medicine. The patient is a 50 years old female diagnosed with functional dyspepsia. The patient had gastric discomfort and alternation between diarrhea and constipation. All symptoms showed nearly complete remission with continued korean traditional medical treatment. The patient had been injected with contrast media for Computed tomography(CT) evaluation of her breast cancer history. Rashes appeared on back and abdomen, and urticaria and pruritus appeared on the patient's finger 1 day after injection. We prescribed Goreisan(TSUMURA CO &, TJ-17) and acupuncture on Quchi(LI11), Zusanli(ST36), Yangxi(LI5), Yanggu(SI5). Consequently, the drug eruption showed remarkable improvement. So the author reports korean traditional medicine is effective complementary treatment for drug eruption.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.3
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• pp.175-183
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• 2012

Objectives : The purpose of this report is to know the effect of Younkyopaedok-san(連翹敗毒散), Sammulhwanggum-tang(三物黃芩湯) on eczema worsened by drug eruption and Gungguigyoae-tang(芎歸膠艾湯) on chronic eczema. Methods : We experienced one case of eczema treated with Younkyopaedok-san, Sammulhwanggum-tang and Gungguigyoae-tang. We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and clinical symptoms were gradually disappeared. Conclusion : Younkyopaedok-san, Sammulhwanggum-tang and Gungguigyoae-tang had improved the signs and symptoms of eczema. 1. Younkyopaedok-san and Sammulhwanggum-tang were effective on the treatment of inflammatory eczema. 2. Gungguigyoae-tang was effective on the treatment of chronic eczema.

• The Journal of the Society of Stroke on Korean Medicine
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• v.8 no.1
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• pp.52-57
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• 2007

Drug eruption is a relatively commin dermatological disorder and may cause significant problems. The treatment is to stop using a drug that may cuase a drug eruption. In some cases, steroids and antihistamines can be used supportively. According to some reports, Onchungeum(溫淸飮) has steroid-like effects and antihistaminic effects. We administered Onchungeum(溫淸飮) a patient with severe itching because of a drug eruption. After administration of Onchungeum(溫淸飮), itching decreased to much degrees. It can be suggested that Onchungeum(溫淸飮) can be used to treat symptoms of allergic skin disease like a drug eruption.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.2
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• pp.104-108
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• 2005

Drug eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Maculopapular, urticarial, morbilliform, papulosquamous, pustular, and bullous morphologies may be encountered. Adverse drug reactions also can cause pruritus or dysesthesia unaccompanied by rash. We treated a patient suffered from maculopapular rash and pruritus with acupuncture, herb medication and wet dressing. After treatment we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of drug eruption.

• Journal of Sasang Constitutional Medicine
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• v.15 no.2
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• pp.111-116
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• 2003

Drug Eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Hereby this report is about a remedial value of Gwaghyangjungkisan which was prescribed for a 78 year-old male featuring Soeumin who had suffered from papular eruption after taking a medicine composed of extract of gingko leaves.

• Journal of Yeungnam Medical Science
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• v.12 no.2
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• pp.405-411
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• 1995

Lichenoid drug eruption is lichenoid skin eruptions caused by certain drugs and compounds, and can be identical or similiar to lichen planus. A 75-year-old woman who had taken antituberculosis medication(INH, ethambutol, rifampin) for 4 months developed pruritic generalized erythematous papular eruptions on the trunk and extremities, alopecia and nail dystropy. Histopathologic findings were hyperkeratosis, hypergranulosis, hydrophic degenaration of basal layer, band like lymphohistiocytic infiltration in the upper dermis and perivascular lymphohistiocytic infiltration in the deep dermis. She was treated with systemic corticosteroid, and then skin lesion were slightly improved. After termination of antituberculosis medication, skin lesions were markedly improved with residual hyperpigmentation. Alopecia and nail dystrophy were also improved.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.256-264
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• 2007

Objective : This study describes a case of urticarial drug eruption assumed to be caused by non-steroidal anti- inflammatory drugs (NSAIDs) treated with oriental medicine and acupuncture. Methods : We studied the case of 20-years-old drug eruption patient. The patient complained of urticaria, angioedema, itching and burning sensation after taking NSAIDs. The indications for NSAIDs prescribed were common cold symptom and sore throat. For diagnosis, blood test and urinalysis were done. For treatment, acupuncture and herbal-medicine treatment were applied. Results : The patient of this report were examined for 13 days. The radiological finding was within normal limits. The WBC, neutrophil, lymphocyte and eosinophil level normalized during admission. After 3 days, itching and wheal reaction of whole body disappeared except facial symptom. The angioedema, itching and wheal reaction in the face was almost improved in the 4th day after discharge. Conclusions : We may expect that the oriental medical therapy improves the urticarial drug eruption caused by NSAIDs.

• The Journal of Internal Korean Medicine
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• v.24 no.4_2
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• pp.1075-1079
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• 2003

BacJung-pil(百中丸) using in stagnation-syndrome of gi and blood(痺證) is a expience prescription, A female patient diagnosed as wind syndrome of head(頭風), and stagnation-syndrome of gi and blood(痺證) showed severe pruritus, rash and eruption of skin. After the patient took BackJun-Pill, two hours later, We examined her change and witnessed macular papule and severe pruritus. Those symptoms disappeared in 7 days since we administer anti-histamine, steroid and GamDu-TangGamiBang(甘豆湯加味方).

• Korean Journal of Biological Psychiatry
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• v.16 no.4
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• pp.266-270
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• 2009

Adverse drug reactions are very common in clinical practice, and skin is one of the most frequent organs for adverse drug reactions. We report a case of a 71-year-old male patient who developed skin eruptions after switching formulation of quetiapine immediate release(IR) to quetiapine extended release(XR). He had been taking quetiapine IR(400mg/day) for treatment of manic episode which was developed one year ago. The patient showed great improvement of symptoms after taking quetiapine IR for about one year, thus dosage of medication was reduced to 50mg/day on the average. Unfortunately dose reduction has tended to worsen symptoms, so dose of quetiapine was increased again to 200mg/day with formulation changes to XR. Two days after he took new formulation, erythematous papules were occurred over his anterior neck and ventral side of left wrist. As he stopped quetiapine XR, the skin lesions gradually subsided. And he was successfully treated with readministration of quetiapine IR without any skin lesions.