• Journal of Sensor Science and Technology
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• v.31 no.1
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• pp.57-63
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• 2022

This study describes a system that monitors the tool and cutting state of automatic beveling operation in real time. As a signal for cutting state monitoring, a motor current detected from the spindle drive system of the automatic beveling machine is used to monitor abnormal state. Because automatic beveling is processed using a face milling cutter, the cutting force mechanism is the same as the milling process. The predicted cutting torque is obtained using a cutting force model based on specific cutting resistance. Then, the predicted cutting torque is converted into the spindle motor current value, and cutting state stability is diagnosed by comparing it with the motor current value detected during beveling operation. The experimental results show that the spindle motor current can detect abnormal cutting state such as overload and tool wear during beveling operation, and can diagnose the cutting stability using the proposed equip-current line diagram.

• Journal of Drive and Control
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• v.19 no.1
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• pp.51-61
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• 2022

This paper presents a model-free system based on a framework of a backstepping sliding mode control (BSMC) with a radial basis function neural network (RBFNN) and adaptive mechanism for electro-hydraulic systems (EHSs). First, an EHS mathematical model was dedicatedly derived to understand the system behavior. Based on the system structure, BSMC was employed to satisfy the output performance. Due to the highly nonlinear characteristics and the presence of parametric uncertainties, a model-free approximator based on an RBFNN was developed to compensate for the EHS dynamics, thus addressing the difficulty in the requirement of system information. Adaptive laws based on the actor-critic neural network (ACNN) were implemented to suppress the existing error in the approximation and satisfy system qualification. The stability of the closed-loop system was theoretically proven by the Lyapunov function. To evaluate the effectiveness of the proposed algorithm, proportional-integrated-derivative (PID) and improved PID with ACNN (ACPID), which are considered two complete model-free methods, and adaptive backstepping sliding mode control, considered an ideal model-based method with the same adaptive laws, were used as two benchmark control strategies in a comparative simulation. The simulated results validated the superiority of the proposed algorithm in achieving nearly the same performance as the ideal adaptive BSMC.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.01a
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• pp.443-445
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• 2023

Following the global financial crisis, the global value chain contracted, and characteristics of "reverse globalization" of the economy and trade gradually emerged. This is due to the term "reverse globalization" referring to a shift away from globalization. Within a short period of time, the phenomenon known as "reverse globalization" developed as an inescapable obstacle, coinciding with the development and dissemination of the COVID-19 virus. At some time in the distant future, the "reverse globalization" of economic trade and the "globalization" of the digital economy will co-dominate the shifting trend of the global economic landscape. This will happen gradually over time. The goal of this research is to look at the minor changes that happened in the methods and techniques used by the economic mechanism known as "globalization against the flow." It employs Chinese smart manufacturing companies as a model and proposes a digital drive model to investigate the prospects and constraints of smart manufacturing technology enterprise innovation development under "reverse globalization," with the goal of establishing a digital innovation development path. The theoretical insights given in this study have the potential to serve as a reference for China as it attempts to build a new growth pattern based on a double-cycle and promote a new type of globalization.

• IMMUNE NETWORK
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• v.21 no.2
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• pp.16.1-16.8
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• 2021

Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with severe COVID-19. However, the mechanism underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced NET formation has not yet been elucidated. Here we show that 2 viral proteins encoded by SARS-CoV-2, the nucleocapsid protein and the whole spike protein, induce NET formation from neutrophils. NET formation was ROSindependent and was completely inhibited by the spleen tyrosine kinase inhibition. The inhibition of p38 MAPK, protein kinase C, and JNK signaling pathways also inhibited viral protein-induced NET formation. Our findings demonstrate one method by which SARSCoV-2 evades innate immunity and provide a potential target for therapeutics to treat patients with severe COVID-19.

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.3
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• pp.146-157
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• 2024

Despite numerous air mattresses marketed to prevent Pressure Ulcers (PU), none have fully succeeded due to residual pressure surpassing critical levels. We introduces an innovative medical bed system aiming at complete PU prevention. This system employs a unique 4-bar link mechanism, moving keys up and down to manage body pressure. Each of the 17 keys integrates a sensor controller, reading pressure from 10 sensors. By regulating motor input, we maintain body pressure below critical levels. Keys are equipped with a servo drive and sensor controller, linked to the main controller via two CAN series. Using fuzzy or PI/IP controllers, we adjust keys to minimize total error, dispersing body pressure and ensuring comfort. In case of controller failure, keys alternate swiftly, preventing ulcer development. Through experimental tests under varied conditions, the fuzzy controller with tailored membership functions demonstrated swift performance. PI control showed rapid convergence, while IP control exhibited slower convergence and oscillations near zero error. Our specialized medical robot bed, incorporating 4-bar links and pressure sensors, underwent testing with three controllers-fuzzy, PI, and IP-showcasing their effectiveness in keeping body pressure below critical ulcer levels. Experimental results validate the proposed approach's efficacy, indicating potential for complete PU prevention.

• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.115-121
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• 2018

Upon sensing of microbial infections or endogenous danger signals in macrophages, inflammasome signaling plays a significant role in triggering inflammatory responses via producing interleukin (IL)-$1{\beta}$. Recent studies revealed that active caspase-1, a product of the inflammasome complex, causes maturation of inactive pro-IL-$1{\beta}$ into the active form. However, the underlying mechanism by which this leaderless cytokine is secreted into the extracellular space remains to be elucidated. In this study, we demonstrated that prolonged lipopolysaccharide (LPS) treatment to macrophages could trigger the unexpected maturation and extracellular release of IL-$1{\beta}$ through a nucleotide-binding oligomerization domain-like receptor family, pyrin domain-containing 3 (NLRP3)-independent manner. Short-term treatment (less than 6 h) of LPS induced robust production of the IL-$1{\beta}$ precursor form inside cells but did not promote the maturation and secretion of IL-$1{\beta}$ in bone marrow-derived macrophages or peritoneal macrophages. Instead, prolonged LPS treatment (more than 12 h) led to a significant release of matured IL-$1{\beta}$ with no robust indication of caspase-1 activation. Intriguingly, this LPS-triggered secretion of IL-$1{\beta}$ was also observed in NLRP3-deficient macrophages. In addition, this unexpected IL-$1{\beta}$ release was only partially impaired by a caspase-1 and NLRP3 inflammasome inhibitor. Collectively, our results propose that prolonged exposure to LPS is able to drive the maturation and secretion of IL-$1{\beta}$ in an NLRP3 inflammasome-independent manner.

• The Transactions of the Korean Institute of Power Electronics
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• v.4 no.5
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• pp.483-490
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• 1999

In this paper, the cost-effective design of output reactor which is USCD to suppress the over-voltage at the m motor terminal in the Adjustable Speed Drives(ASD) application is proposed. In the elevator drive svstem. the R IXlwer cable length is relatively shorter than other ASD applications and then the over voltage at the motor terminal depends on the frequency characteristics of the output reactor at the over voltage operating frequency. The over-voltage suppression mechanism of output reactor in ASD application is analyzed and the dominant parameters of output reactor for the over-voltage supression are extracted. Using these as the design values and considering the high frequency characteristics of iron core in the reactor. a new c cost-effective structure of output reactor is proposed. Experimental results of the conventional reactor and the p proposed reactor with a l5kW induction motor are given to verify the propoSLD scheme.

• Journal of Biosystems Engineering
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• v.34 no.5
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• pp.315-324
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• 2009

Various types of vibration are transmitted to operators of agricultural tractors while working in the field. Most harmful vibration to human body is ride vibrations with low frequency ranging from 1 to 10 Hz, caused by rough terrain. These ride vibration has vertical and rotational components. This study was conducted to develop an active seat suspension system with two degrees of freedoms, enabling effectively reduce vibrations in vertical and pitch motions. Therefore, a mechanism for the active seat suspension was developed, and an electro-hydraulic servo system and a controller to drive the active seat suspension system were also developed in this study. A simulation model was developed to evaluate how the active seat suspension system effectively reduce the vibrations transmitted to the base of seat. Active seat suspension was optimized to enhance the performance using the developed simulation model. The performance of the seat suspension system was evaluated according to the test codes described in EEC78/764 in order to investigate the feasibility of application to agricultural tractors. The result showed that the developed active seat suspension system could reduce the magnitude of vertical vibration up to 80% for the input vibrations according to the test codes described in EEC78/764. The system could reduce the rotational displacement of ${\pm}\;2.5$ degrees up to 50% for the pitch vibration on the average in the frequency range of 1 to 2 Hz.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.12
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• pp.807-814
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• 2015

A control rod drive mechanism(CRDM) is a reactor regulating system, which inserts, withdraws or maintains a control rod containing a neutron absorbing material within a reactor core to control the reactivity of the core. The top-mounted CRDM for Jordan Research and Training Reactor(JRTR) with 5 MW power has been designed and fabricated based on the HANARO's experience through KAERI and DAEWOO consortium project. This paper describes the performance qualification test results to demonstrate the operability of a prototype and four production CRDMs during the reactor lifetime. The driving performance, the drop performance and the endurance tests for CRDM are carried out at a test rig simulating the actual reactor conditions. A vibration of internal components due to the coolant flow is also measured using a laser vibrometer. As a result, the CRDMs are driven having a good driving performance without a malfunction between command and output signals for the stepping motor. Also, the pure drop time and the impact acceleration are within 0.72 s and 4.2 g to meet the design requirements, and the vibrational displacement of control rod is measured as maximum $5.2{\mu}m$.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.6 s.183
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• pp.166-173
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• 2006

In this study, a probe array has been developed for use in a data storage device that is based on scanning probe microscope (SPM) and MEMS technology. When recording data bits by poling the PZT thin layer and reading them by sensing its piezoresponse, commercial probes of which the tip heights are typically shorter than $3{\mu}m$ raise a problem due to the electrostatic forces occurring between the probe body and the bottom electrode of a medium. In order to reduce this undesirable effect, a poly-silicon probe with a high aspect-ratio tip was fabricated using a molding technique. Poly-silicon probes fabricated by the molding technique have several features. The tip can be protected during the subsequent fabrication processes and have a high aspect ratio. The tip radius can be as small as 15 nm because sharpening oxidation process is allowed. To drive the probe, electrostatic actuation mechanism was employed since the fabrication process and driving/sensing circuit is very simple. The natural frequency and DC sensitivity of a fabricated probe were measured to be 18.75 kHz and 16.7 nm/V, respectively. The step response characteristic was investigated as well. Overshoot behavior in the probe movement was hardly observed because of large squeeze film air damping forces. Therefore, the probe fabricated in this study is considered to be very useful in probe-based data storages since it can stably approach toward the medium and be more robust against external shock.