• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.10
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• pp.1530-1540
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• 2009

Life expectancy has increased and people are more concerned with keeping their 'youth'. Appearance is a competitive edge and people are caught up in a baby face fad that has expanded into a culture and beauty trend. This study examined the definitions and phrenological characteristics of a baby face and the causes of the baby face fad in a review of the baby face as a "sociocultural and beauty cultural code" based on literature, journals, previous papers, and Internet materials. Anatomically speaking, a "baby face" refers to a face that keeps the features of a child's face without aging signs. The baby face fad gained momentum due to the influences of the digital culture, the encouragement of the mass media, changes to the social structure, dietary improvements, new living styles, and an evolving aesthetic sense. The results reveal the sociocultural backgrounds behind the "baby face fad" settling down as a part of culture in addition to the phrenological characteristics of a baby face. It is also estimated that the baby face fad could affect the beauty culture and trends as a social phenomena.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.12 no.2
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• pp.50-57
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• 2016

The study presents structural integrity assessment of ductility degradation of a baffle former assembly by performing finite element analysis considering real loading conditions and stress triaxiality. Variations of fracture strain curves of type 304 austenitic stainless steel with stress triaxiality are derived based on the previous study results. Temperature distributions during normal operation such as heat-up, steady state, and cool-down are calculated via finite element temperature analysis considering gamma heating and heat convection with reactor coolant. Variations of stress and strain state during long operation period are also calculated by performing sequentially coupled temperature-stress analysis. Fracture strain is derived by using the fracture curve and the stress triaxility. Finally, variations of ductility degradation damage indicator with the fracture strain and the equivalent inelastic strain are investigated. It is found that maximum value of the ductility degradation damage index continuously increases and becomes 0.4877 at 40 EFPYs. Also, the maximum value occurs at top and middle inner parts of the baffle former assembly before and after 20 EFPYs, respectively.

• Journal of Korean Institute of Industrial Engineers
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• v.30 no.2
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• pp.165-174
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• 2004

It is known that one out of every ten people walking down the street is left-handed. In daily living, left-handed people come across hardwares and facilities that were designed for right-handed people. Most tools, utensils, office equipment, home appliances, clothes, medical instruments, sporting goods, weapons, and public facilities are made for the right-handed person. Many left-handed people thus have trouble with living in our environments. In this study, 1,933 Korean male and female subjects aging from 10 to 82 were selected to investigate the various statistics about hand dominance and their employment characteristics of preferred hand in handling diverse products and facilities. The statistics showed that 5.6% were left-handed and 7.6% were ambidexter. There were strong tendency that left-handed people use more left hand when take action that force is required than when take exquisite action. Ambidexter and right-handed people use more right hand when they take exquisite action is required than when take action that force is required. It was found from these results that people use their hands differently depending on the hand dominance when they handle things, hence this should be considered in designing hand control devices.

• Journal of Integrative Natural Science
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• v.6 no.3
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• pp.125-137
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• 2013

Promising evidence suggests that amyloid beta peptide ($A{\beta}$), a key mediator in age-dependent neuronal and cerebrovascular degeneration, activates death signalling processes leading to neuronal as well as non-neuronal cell death in the central nervous system. A major cellular event in $A{\beta}$-induced apoptosis of non-neuronal cells, including cerebral endothelial cells, astrocytes and oligodendrocytes, is mitochondrial dysfunction. The apoptosis signalling cascade upstream of mitochondria entails $A{\beta}$ activation of neutral sphingomyelinase, resulting in the release of ceramide from membrane sphingomyelin. Ceramide then activates protein phosphatase 2A (PP2A), a member in the ceramide-activated protein phosphatase (CAPP) family. PP2A dephosphorylation of Akt and FKHRL1 plays a pivotal role in $A{\beta}$-induced Bad translocation to mitochondria and transactivation of Bim. Bad and Bim are pro-apoptotic proteins that cause mitochondrial dysfunction characterized by excessive ROS formation, mitochondrial DNA (mtDNA) damage, and release of mitochondrial apoptotic proteins including cytochrome c, apoptosis inducing factor (AIF), endonuclease G and Smac. The cellular events activated by $A{\beta}$ to induce death of non-neuronal cells are complex. Understanding these apoptosis signalling processes will aid in the development of more effective strategies to slow down age-dependent cerebrovascular degeneration caused by progressive cerebrovascular $A{\beta}$ deposition.

• Advances in Traditional Medicine
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• v.7 no.2
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• pp.182-190
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• 2007

Alzheimer's disease is a neurodegenerative disorder associated with a decline in cognitive abilities. Dementia is one of the aged related mental problems and a characteristic symptom of Alzheimer's disease. Nootropic agents like piracetam and cholinesterase inhibitors like $Donepezil^{\circledR}$ are used in situations where there is organic disorder in learning abilities, but the resulting side-effects associated with these agents have limited their utility. Foeniculum (F.) vulgare Linn. is widely used in Indian traditional systems of medicines and also as a house remedy for nervous debility. The present work was undertaken to assess the potential of F. vulgare as a nootropic and anti-cholinesterase agent in mice. Exteroceptive behavioral models such as Elevated plus maze and Passive avoidance paradigm were employed to assess short term and long term memory in mice. To delineate the possible mechanism through which F. vulgare elicits the anti-amnesic effects, its influence on central cholinergic activity was studied by estimating the whole brain acetylcholinesterase activity. Pretreatment of methanolic extract of fruits of F. vulgare Linn. for 8 successive days, ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging induced memory deficits in mice. F. vulgare extract significantly decreased transfer latencies of young mice and aged mice, increased step down latency and exhibited significant anti-acetyl cholinesterase effects, when compared to piracetam, scopolamine and control groups of mice. F. vulgare might prove to be a useful memory restorative agent in the treatment of dementia seen in the elderly.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.39 no.4
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• pp.38-44
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• 2007

In order to utilize unsorted ONP, which contains leaflets (printed coated papers), to produce pulp mold, optimum conditions for a repulping process were investigated with a laboratory high consistency pulper. It was concluded that medium or high consistency pulping is necessary to accelerate the rate of deflaking of unsorted ONP. Considering flake content, fines content and pulping energy, the optimum conditions for the laboratory Helico pulper were 11% of repulping concentration and 3 min of repulping time. The repulping temperature shall be at least $30^{\circ}C$. Aging of paper slows down the rate of de flaking but in an actual pulp molding process its effect could be negligible.

• The Journal of Korean Medicine
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• v.38 no.2
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• pp.31-40
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• 2017

Objectives: We investigated the effect of acupuncture on memory function in relation with neurogenesis in old rats. Methods: In this study, a step-down avoidance task for short-term memory and Y-maze task for spatial memory capability were conducted. Western blot analysis for brain-derived neurotorphic factor (BDNF) and tyrosine kinase B (TrkB), and immunohistochemistry for 5-bromo-2'-deoxyuridine (BrdU) were performed. Results: Short-term memory and spatial memories were decreased in the old-aged rats. Expressions of BDNF and TrkB in the hippocampus were significantly decreased in the old-aged rats. Neurogenesis in the hippocampal dentate gyrus was also decreased in the old-aged rats. However, acupuncture treatment alleviated impairment of short-term and spatial memories induced by ageing. Acupuncture also increased the expressions of BDNF and TrkB and enhanced neurogenesis in the hippocampus. The present study showed that acupuncture alleviated ageing-induced short-term and spatial memory loss by increasing of BDNF and neurogenesis. Acupuncture at ST41-acupoint showed most potent effect than at ST36-acupoint or non-acupoint. Conclusions: Acupuncture might be used as the effective therapeutic modality to ameliorate the age-related decrease of brain functions.

• Journal of the Korean Society of Clothing and Textiles
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• v.38 no.5
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• pp.705-717
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• 2014

The interest and importance of appearance can be expanded by changes in social awareness about appearance, the extension of life expectancy, and the development of science, technology and technology and medicine. Especially, down-aging syndrome through a variety of mediums, amplifies consumer's interest in youth-pursing. This study discusses the relationship of youth-pursuing, appearance concern and appearance management behavior focused on the middle-aged. Data were collected from 300 females aged 40-65 in the areas of Seoul, Daejeon and Chungbuk areas. The data were analyzed by descriptive statistics, factor analysis, regression analysis, using the SPSS-WIN 20.0 program. Youth-pursuing formed social, psychological, and appearance factors. Each of these three dimensions influenced the appearance concern; consequently, appearance had the highest influence. Only appearance influenced appearance management behavior in the regression analysis of youth-pursuing and appearance management behavior. Appearance concern affected significantly appearance in the management behavior of the dimension regression analysis results for the appearance concern and appearance management behavior.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.04a
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• pp.106-106
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• 2018

Cyanidin 3 - rutinoside chloride (CRC) is major anthocyanin, found in Schisandra chinensis, is known to have antioxidant, anticancer, anti-inflammatory, tonic, and anti-aging effects in Korea, China and Japan. In the present study, the human mast cell line (HMC-1) was used to investigate the effects on the production of pro-inflammatory mediators. In this study, CRC showed no cytotoxicity in HMC-1. CRC significantly inhibited the secretion of inflammatory cytokines such as tumor necrosis factor $(TNF)-{\alpha}$ and interleukin (IL)-6 in PMA plus A23187 cacium ionophore (PMACI)-stimulated HMC-1 cells. In addition, CRC suppressed the serum levels of IgE. Furthermore, CRC decreased the PMACI- stimulated phosphorylation of mitogen activated protein kinases (MAPKs) such as p-ERK, p- JNK and p-P38. These results indicate that the pharmacological actions of CRC suggest their potential activity for treatment of allergic inflammation through the down-regulation of mast cell activation.

• Physical Therapy Korea
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• v.13 no.4
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• pp.16-22
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• 2006

Falling is a serious problem associated with aging. Unintentional injury, which most often results from falling, is one of the leading causes of death in elderly people. The purpose of this study is to investigate the risk factors of falls and to compare characteristics of people who fall with that of non-fallers among the rural community-dwelling elderly of Korea. A sample of 201 people, living in the community, aged 60 years and over was taken from the members of a center for seniors located in Jecheon city. The mean age of the participants was 70.5 years of age. The participants are comprised of 151 women and 50 men. Eighty four of the 201 participants (41.8%) fell during the previous year. Twenty two of the fallers (26.2%) fell down more than two times. It was found that fallers had poorer eyesight, multiple chronic diseases and a more difficult time walking than non-fallers. In the logistic regression analysis of falls, only the difficulty of walking one kilometer (OR=2.4) and chronic diseases (OR=2.5) have shown an increased risk of falls. The risk of recurrent falls is, in addition, influenced by the difficulty of walking one kilometer. The result of our study shows that the impairment of mobility was the strongest risk factor of recurrent falling.