• Title/Summary/Keyword: Dose indicator

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Development of a Qualitative Dose Indicator for Gamma Radiation Using Lyophilized Deinococcus

  • Lim, Sangyong;Song, Dusup;Joe, Minho;Kim, Dongho
    • Journal of Microbiology and Biotechnology
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    • v.22 no.9
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    • pp.1296-1300
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    • 2012
  • The feasibility of using Deinococcus showing strong resistance to both desiccation and ionizing radiation as a dose indicator of gamma radiation exposure was evaluated. Three Deinococcus strains having different levels of radiation resistance, Deinococcus radiodurans (DRD), Deinococcus radiopugnans (DRP), and the DRD pprI mutant (DRM), were selected to develop an appropriate dose indicator for a broad range of exposures. DRD, DRP, and DRM cultures with different numbers of cells [${\sim}10^7$ to $10^3$ colony forming units (CFU)/$100{\mu}l$] were lyophilized and subjected to various doses of gamma radiation to determine a critical dose that inhibited bacterial growth completely. Finally, a combination of DRD at ${\sim}10^7$ and ${\sim}10^6$ CFU, DRP at ${\sim}10^5$ CFU, and DRM at ${\sim}10^4$ CFU successfully indicated exposure to 5, 10, 20, and 30 kGy of gamma radiation, respectively. This study shows the possibility of developing a qualitative indicator of radiation exposure using Deinococcus.

Indicator microorganisms concentrations change after irrigation of wastewater treatment effluent in paddy field for water reuse (용수 재이용을 위한 하수처리수 관개 후 논에서의 지표성 미생물의 거동)

  • Jung, Kwang-Wook;Yoon, Chun-G.
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2003.10a
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    • pp.583-586
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    • 2003
  • The objective of this research was to examine the significance of change to indicator microorganisms (TC, FC, and E. coli) in the paddy field and repair of UV disinfected secondary effluent. Average concentrations of Microorganisms were maintained by more than about 1,000 MPN/100mL in paddy field after irrigation. Microorganism repair was evaluated in relation to UV dose in photoreactivating light and dark. In addition, a significant inverse relationship was found between UV dose and repair of indicator microorganisms when the research of wastewater was conducted in the condition of low and high UV dose.

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Inactivation of various bacteriophages by different ultraviolet technologies: Development of a reliable virus indicator system for water reuse

  • Bae, Kyung Seon;Shin, Gwy-Am
    • Environmental Engineering Research
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    • v.21 no.4
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    • pp.350-354
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    • 2016
  • There is an urgent need to identify more reliable indicator systems for human pathogenic viruses in water reuse practice. In this study, we determined the response of different bacteriophages representing various bacteriophage groups to different ultraviolet (UV) technologies in real wastewater in order to identify more reliable bacteriophage indicator systems for UV disinfection in wastewater. Bacteriophage ${\varphi}X174$ PRD1, and MS2 in two different real wastewaters were irradiated with several doses of both low pressure (LP) and medium pressure (MP) UV irradiation through bench-scale UV collimated apparatus. The inactivation rate of ${\varphi}X174$ by both LP and MP UV was rapid and reached ${\sim}4{\log}_{10}$ within a UV dose of $20mJ/cm^2$. However, the inactivation rates of bacteriophage PRD1 and MS2 were much slower than the one for ${\varphi}X174$ and only ${\sim}1{\log}_{10}$ inactivation was achieved by the same UV dose of $20mJ/cm^2$. Overall, the results of this study suggest that bacteriophage MS2 could be a reliable indicator for human pathogenic viruses for both LP and MP UV disinfection in wastewater treatment processes and water reuse practice.

Basic Principles of CT Dose Index and Understanding of CT Parameter for Dose Reduction Technique (CT선량지표의 원리와 선량감소 방안에 관한 연구)

  • Kim, Jung-Su;Kwon, Soon-Mu;Kim, Jung-Min
    • Journal of radiological science and technology
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    • v.38 no.1
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    • pp.51-61
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    • 2015
  • Computed tomography(CT) using radiation have potential risks. All medical radiographic examinations should require the justification of medical imaging examinations and optimization of the image quality and radiation exposure. The CT examination was higher radiation dose then general radiography. Especially pediatric CT examinations need to great caution of radiation risk. Because of pediatric patient was more sensitive of radiation exposure. Therefore, physician should consider the knowledge of CT radiation exposure indicator information for reduce a needless radiation exposure. This article was aim to understanding of CT exposure indicator, size-specific dose estimates by American Association of Physicists in Medicine (AAPM) report 204, XR 25 and understanding of CT dose reduction technique.

Cytokinesis-blocked micronuclei in the human peripheral lymphocytes following low dose γ-rays irradiation (저선량의 감마선 피폭된 사람 말초 임파구의 미소핵을 이용한 방사선 생물학적 피폭선량 측정법 연구)

  • Kim, Tae-hwan
    • Korean Journal of Veterinary Research
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    • v.41 no.1
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    • pp.99-104
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    • 2001
  • To determine if micronucleus (MN) assay could be used to predict the absorbed dose of victims after accidental radiation exposure, we carried out to assess the absorbed dose depending on the numerical changes of MN in human peripheral blood lymphocytes after $^{60}Co\;{\gamma}-rays$ exposure in the range of 0.25 to 1 Gy, respectively. The MNs were observed at very low doses, and the numerical changes according to doses. Satisfactory dose-effect calibration curve is observed after low dose irradiation of human lymphocytes in vitro. When plotting on a linear scale against radiation dose, the line of best fit was $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$. The dose-response curve for MN induction immediately after irradiation was linear-quadratic and has a significant relationship between the frequencies of MN and dose. These data show a trend towards increase of the numbers of MN with increasing dose. The number of MN in lymphocytes that were observed in the control group is $0.1610{\pm}0.0093/cell$. Accordingly, MN assay in human peripheral lymphocytes could be a useful in viva model for studying radio-protective drug sensitivity or screening test, microdosimertic indicator and radiation-induced target organ injury. Since MN assay is simple, rapid and reproducible, it will also be a biodosimetric indicator for individual dose assessment after accidental exposure.

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Monitoring Performance of Camera under the High Dose-rate Gamma Ray Environment (고선량율 감마선 환경하에서의 카메라 관측성능)

  • Cho, Jai-Wan;Jeong, Kyung-Min
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.8
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    • pp.1172-1178
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    • 2012
  • In this paper, the gamma ray irradiation test results of the CCD cameras are described. From the low dose-rate (2.11 Gy/h) to the high dose-rate (150 Gy/h) level, which is the same level when the hydrogen explosion was occurred in the 1~3 reactor unit of the Fukushima nuclear power plant, the monitoring performance of the cameras owing to the speckles are evaluated. The numbers of speckles, generated by gamma ray irradiation, in the image of cameras are calculated by image processing technique. And the legibility of the sensor indicator (dosimeter) owing to the numbers of the speckles is presented.

Disinfection and Reactivation of Microorganisms after UV Irradiation for Agricultural Water Reuse of Biofilter Effluent

  • Jung, Kwang-Wook;Yoon, Chun-G.;Hwang, Ha-Sun;Ham, Jong-Hwa
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.45 no.7
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    • pp.94-106
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    • 2003
  • A pilot study was performed to examine the feasibility of UV disinfection system and the reactivation of indicator microorganisms (TC, FC, E. coli) after UV irradiation for agricultural reuse of reclaimed water. Photoreactivation and dark repair enable UV-inactivated microorganisms to recover and may reduce the efficacy of UV inactivation, which might be drawbacks of the UV disinfection method. The effluent of biofilter for 16-unit apartment house was used as input to the UV disinfection system, and average SS and BOD concentration were 3.8 and 5.7 mg/L, respectively, and the mean level of total coliform was in the range of $1.0\times10^4$ MPN/100mL. UV disinfection was found to be effective and it reduced mean concentration of indicator microorganisms (total coliform, fecal coliform, and E. coli) to less than 100 MPN/100mL within 60s exposure using 17, 25, and 40W lamps. Two UV doses of 6 and 16 mW$\cdot$s/$\textrm{km}^2$ were applied and microorganisms reactivation was monitored under the dark, photoreactivating light, and solar irradiation. Microorganisms reactivation was observed in the UV dose of 6 mW$\cdot$s/$\textrm{km}^2$, and numbers increased up to 5% at the photoreactivating light and 1% at the dark. However, microorganisms were inactivated rather than reactivated at the solar radiation and numbers decreased to non-detectible level about below 2 MPN/100mL in 4 hours. In the case of 16 mW$\cdot$s/$\textrm{km}^2$, microorganism reactivation was not observed indicating that UV dose might affect the reactivation process such as photoreactivation and dark repair. Therefore, concerns associated with microorganism reactivation could be controlled by sufficient UV dose application. Agricultural reuse of reclaimed water might be even less concerned due to exposure to the solar irradiation that could further inactivate microorganisms. The pilot study result is encouraging, however, sanitary concern in water reuse is so critical that more comprehensive investigation is recommended.

Milk Yield and Immune Response of Periparturient and Early Lactation Friesian Cows Fed Diets Supplemented with a High Level of Amino-acid Chelated Chromium

  • Terramoccia, S.;Bartocci, S.;Lillini, E.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.8
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    • pp.1098-1104
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    • 2005
  • The trial was carried out on twenty-one Friesian cows at the end of eight months gestation, nine multiparous and twelve primiparous; allocated into three groups (1 control, 2 and 3 experimental). The same diet was administred to all three groups before partum (12.8 kg DM/head/day) and after partum (18.8 kg DM/head/day). The cows in groups 2 and 3 received two different daily quantities of amino-acid chelated chromium (0.6 and 1.2 mg Cr/kg DM) from 4 weeks prior to presumed parturition to 6 weeks after. The milk yield control was carried out at 15, 30, 42 and 60 days. All animals were immunised two weeks prior to the presumed parturition and two weeks after with the following antigens: ovalbumin and brucellergene. Blood samples were collected weekly to monitor humoral and cell-mediated immune responses. When analysing the results of antibody immunity (ovalbumin) in the sixth blood collection both treated groups significantly increased compared to group 1 (0.5230 and 0.4536 vs. 0.1812 OD; p<0.05). The results of the cell-mediated immune response (brucellergene) had significant differences (p<0.10) in correspondence to the third (between group 2 and control) and the fifth (between groups 3 and 2) blood collection. Significant differences in fat corrected milk were observed at 42 days between group 3 and the other two groups (31.01 vs. 26.99 and 28.66 kg/d, p<0.05) and at 60 days between group 3 and control (30.88 vs. 26.69 kg/d, p<0.05). Before partum and at partum a positive immune response was obtained with a lower dose of chromium. After partum a positive immune response, anti-OVA indicator, was obtained with the higher dose of chromium while, $\gamma$-IFN indicator, with the lower dose. A significant increase of the milk yield resulted at both 42 and 60 days with the highest level of chromium.

Evaluation of Radiation Dose according to Aneurysm Size and Location during Cerebral Aneurysm Coil Embolization (뇌동맥류 코일 색전술 시술 시 동맥류 크기 및 위치에 따른 방사선량 평가)

  • An, Hyun
    • Journal of radiological science and technology
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    • v.45 no.5
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    • pp.407-412
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    • 2022
  • Cerebral aneurysm coil embolization has the advantages of accurate, low patient burden, and fast recovery time, but efforts are needed to reduce dose due to the burden of exposure radiation dose during interventional procedures. In this study, the area dose product(DAP/Gy·cm2) and fluoro time(min) according to the size of the aneurysm and the location of aneurysm were investigated according to insurance recognition regulations aneurysm classification cerebral aneurysm coil embolization. According to the research method, classification according to the size and location of the aneurysm is first, the size of the aneurysm is divided into less than 4mm, more than 4mm to less than 8mm, and more than 8mm, and second, the dose to the area based on the location site (DAP/Gy·cm2) and fluoro time(min) based on the location site were observed. As a result, the location of the cerebral aneurysm procedure was found to be the Paraclinoid site. During cerebral aneurysm coil embolization, the area dose was 107 Gy·cm2 and fluoro time was 47.41 minutes, showing lower results than domestic studies, and when comparing the area dose product with foreign studies, the area dose product results were similar to that of Turkey and Saudi Arabia. It is expected that it can be used as an objective analysis indicator to establish diagnostic reference levels (DRLs) and patient radiation defense guidelines according to the size of cerebral aneurysm and location of cerebral aneurysm procedures during interventional procedures.

Selection of mAs with Using Table Strap in Computed Tomography Scan (전산화단층촬영 시 환자 고정 밴드를 이용한 선량의 선택)

  • Lee, Young-Hyen;An, Hyeong-Theck
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.2
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    • pp.63-69
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    • 2011
  • Table strapis patient fixture for securing the patient movements and falls. if it designed to measure the abdominal circumference and used as an indicator of dose selection at CT scan. it will prevent the overexposure of dose without degradation of image quality and efficiently manage dose of each type of body to technician to deal with CT. First, in order to compare the dose used in CT image and qualitative characteristics. reference image is obtained by examining the abdominal phantom in same conditions with the hospital 120 kVp, 200 mAs, D-Dom (Dynamic Dose Of Modulation). SNR, PSNR, RMSE, MAE, CTDIvol of CT images are compared with reference image. for comparing with reference image, the image that Umbilicus level image of Abdomen CT is stored in the PACS were used. For comparison, the top 12 o'clock portion of the air drawn from the same ROI was measured. CTDIvol, mAs, etc. In order to analyze the characteristics of the image, by measuring the length of the umbilicus circumference, pattern of the dose was analyzed. by using the analyzed perimeter and dose information, To be identified visually, fixed band that scale marked were produced. Use them, If the length of circumference of less than 60 cm 100 mAs, Case of 61~80 cm 120 mAs, Case of 80~100 cm 150 mAs, more than 100 cm 200 mAs, dose selection based on the perimeter, the image was applied. by compare analyzed with the Reference Image, image quality was assessed. by compare with existing tests that equally 200 mAs applied, How much was confirmed that the dose reduction. 1. Depending on the Abdominal circumference, the average PSNR(dB) of the image that differently dose applied was 45.794. 2. Comparing with existing test. the dose of scan that adjusted the mAs depending on the circumference was decreased about 40%. SNR and PSNR of the image that obtained by adjusting the standard mAs based on dose modulation were not much different. Therefore, By choosing a low mAs. dose reduction can be obtained. and the dose selection method that measured Abdominal circumference using a fixed band can protect the overexposure and uniformly apply dose of each type of body to technician to deal with CT.

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