• Title/Summary/Keyword: Dose conversion

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Determination of Processing Parameters Affecting the Conversion and Thermal Stability of Photocurable Acrylate-based Binder (아크릴계 광바인더의 전환율과 열안정성 향상을 위한 공정변수 결정)

  • Kim, Byungchul;Seo, Dong Hak;Chae, Heon-Seung;Shin, Seunghan
    • Applied Chemistry for Engineering
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    • v.23 no.1
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    • pp.18-22
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    • 2012
  • Photocurable binder for a transparent glass fiber composite was prepared with alicyclic methacrylate and fluorene-based diacrylate. ANOVA (analysis of variance) analysis was used to know main factors affecting the conversion of photocurable binder. It showed radiation intensity and photoinitiator (PI) concentration were main factors. The conversion of photocurable binder was simply increased with radiation intensity. Its increment however was abated with increasing PI concentration. We found that average conversion of the binder measured by FTIR-ATR was 87% when it was exposed to $5J/cm^2$ of UV dose with 5 wt% of PI. Oxime ester type PI was very effective to get a high degree of conversion, but it caused a yellowing problem. Owing to post-baking process, UV cured film showed an improved thermal stability by increase of conversion and removal of volatile organic compounds. TG% at $260^{\circ}C$ of film cured with 5 wt% of PI (TPO+MBF) and $5J/cm^2$ of UV radiation increased from 95.4 to 99.0% by post-baking at $230^{\circ}C$ for 5 min.

Radiotherapy Technique of High Energy Electron (고에너지 전자선의 방사선 치료 기술)

  • SUH M.W.;PARK J.I.;CHOI H.S.;KIM W.Y.
    • The Journal of Korean Society for Radiation Therapy
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    • v.1 no.1
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    • pp.63-69
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    • 1985
  • High energy electron beams took effect for tumor radio-therapy, however, had a lot of problems in clinical application because of various conversion factors and complication of physical reactions. Therefore, we had experimentally studied the important properties of high energy electron beams from the linear accelerator, LMR-13, installed in Yonsei Cancer Center. The results of experimental studies on the problems in the 8, 10, 12 Mev electron beam therapy were reported as following. 1. On the measurements of the outputs and absorbed does, the ionization type dosimeters that had calibrated by $^{90}Sr$ standard source were suitable as under $3\%$ errors for high energy electrons to measure, but measuring doses in small field sizes and the regions of rapid fall off dose with ionization chambers were difficult. 2. The electron energy were measured precisely with energy spectrometer consisted of magnet analyzer and tele-control detector and the practical electron energy was calculated under $5\%$ errors by maximum range of high energy electron beam in the water. 3. The correcting factors of perturbated dose distributions owing to radiation field, energy and material of the treatment cone were checked and described systematically and variation of dose distributions due to inhomogeneous tissues and sloping skin surfaces were completely compensated. 4. The electron beams, using the scatters; i.e., gold, tin, copper, lead, aluminium foils, were adequately diffused and minimizing the bremsstrahlung X-ray induced by the electron energy, irradiation field size and material of scatterers, respectively. 5. Inproving of the dose distribution from the methods of pendulum, slit, grid and focusing irradiations, the therapeutic capacity with limited electron energy could be extended.

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A comparison of single dose efficacy of Mycoplasma hyopneumoniae bacterin in swine farms with different serological patterns of PRRSV and PCV2

  • Kim, Hye Kwon;Moon, Hyoung Joon;Kim, Eun Mi;Yang, Jeong Sun;Pakr, Seong Jun;Luo, Yuzi;Lee, Chul Seung;Song, Dae Sub;Kang, Bo Kyu;Lee, Jaebum;Park, Bong Kyun
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.267-274
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    • 2008
  • This study was to evaluate the efficacy of single dose Mycoplasma hyopneumoniae (M. hyo)-vaccination in the swine farms which had different serological patterns of porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). A minimum of 240 pigs from each farm was applied, allocating M. hyo vaccinated and control groups. The PRRSV and PCV2 infections were analyzed by serological method (commercial ELISA kit). After administrating pigs a single dose of M. hyo vaccine or control saline at 3 weeks of age, serum antibodies to M. hyo, PRRSV and PCV2 were monitored at 4, 10, 16 and 22 weeks of age. Mortality, weight changes, feed conversion ratio (FCR) and lung score were also evaluated. A single-dose vaccination of M. hyo bacterin was efficacious to reduce mycoplasmal lung lesions and induce good humoral immune response. However, FCR was improved only in one of the three farms where showed seronegative status to both PRRSV and PCV2 in the period from 4 to 16 weeks of age. These results might imply that M. hyo vaccine alone could not overcome the PRRSV and PCV2 infection-associated wasting in the field condition. Therefore, the control of PRRSV and PCV2 should be considered to obtain the better effects of M. hyo vaccination.

Occupational radiation exposure control analyses of 14 MeV neutron generator facility: A neutronic assessment for the biological and local shield design

  • Swami, H.L.;Vala, S.;Abhangi, M.;Kumar, Ratnesh;Danani, C.;Kumar, R.;Srinivasan, R.
    • Nuclear Engineering and Technology
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    • v.52 no.8
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    • pp.1784-1791
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    • 2020
  • The 14 MeV neutron generator facility is being developed by the Institute for Plasma Research India to conduct the lab scale experiments related to Indian breeding blanket system for ITER and DEMO. It will also be utilized for material testing, shielding experiments and development of fusion diagnostics. Occupational radiation exposure control is necessary for the all kind of nuclear facilities to get the operational licensing from governing authorities and nuclear regulatory bodies. In the same way, the radiation exposure for the 14 MeV neutron generator facility at the occupational worker area and accessible zones for general workers should be under the permissible limit of AERB India. The generator is designed for the yield of 1012 n/s. The shielding assessment has been made to estimate the radiation dose during the operational time of the neutron generator. The facility has many utilities and constraints like ventilation ducts, accessible doors, accessibility of neutron generator components and to conduct the experiments which make the shielding assessment challenging to provide proper safety for occupational workers and the general public. The neutron and gamma dose rates have been estimated using the MCNP radiation transport code and ENDF -VII nuclear data libraries. The ICRP-74 fluence to dose conversion coefficients has been used for the assessment. The annual radiation exposure has been assessed by considering 500 h per year operational time. The provision of local shield near to neutron generator has been also evaluated to reduce the annual radiation doses. The comprehensive results of radiation shielding capability of neutron generator building and local shield design have been presented in the paper along with detailed maps of radiation field.

Measurement of Dose Distribution in Small Fields of NEC LINAC 6 MVX Using Films and Tissue Equivalent Phantoms (필름 및 tissue equivalent 팬톰을 이용한 NEC LINAC 6 MVX 소조사면에 대한 선량분포 측정)

  • Suh, Tae-Suk;Park, Dong-Rak;Choe, Bo-Young;Yoon, Sei-Chul;Jang, Hong-Seok;Park, Il-Bong;Kim, Moon-Chan;Bahk, Yong-Whee;Shin, Kyung-Sub
    • Progress in Medical Physics
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    • v.4 no.2
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    • pp.9-17
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    • 1993
  • The purpose of this paper is to develop a simple system to measure dose distribution in small fields of NEC LINAC 6 MVX using film and solid water instead of ion chamber and water phantom. Specific quantities measured include percent depth dose (PDD), off-axis ratio (OAR). We produced square fields of 1 to 3cm in perimeter in 1cm steps measured at SAD of 80cm. The PDD and OAR measured by film was compared with measurement made with ion chamber. We calculated the TMR from the basic PDD data using the conversion formula. The trends of our measured beam data and philips LINAC are similar each other. The measurement for the small field using film and solid water was simple. Hand-made film phantom was especially useful to measure OARs for the stereotactic radiosurgery.

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Effective Doses in the Radial Gamma Radiation Field near a Point Source: Gender Difference and Deviation from the Personal Dose Equivalent (점선원 감마선장에서 유효선량의 성별차 및 개연선량당량과의 차이)

  • Chang, Jai-Kwon;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.22 no.4
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    • pp.299-307
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    • 1997
  • The individual dose equivalent, $H_p$, effective dose, E, and gender specific effective dose, $E^m$ and E$^f$, were evaluated using the male and female phantoms of MIRD type located in the radial gamma radiation field near a point source. The point sources were placed at the distances of 15, 40 and 100 cm in front of the body at different heights. Two radionuclides, $^{137}Cs$ and $^{131}I$, were selected for the illustrative examples. In terms of the gender specific effective doses, $E^f$ is higher than $E^m$ with a few exceptions, e.g. the case where the point source is at the height of reproductive organs, but the differences from the sex- averaged values are not significant enough to justify use of gender specific dose conversion factors for the radial gamma field. The ratios $H_p$/E were in the range of 1 to 3 depending on the source and dosimeter positions when the dosimeter is worn on the front surface of the torso covering from chest to lower abdomen, but varied from 0.34 to 6.5 in extreme cases. When it is assumed that the typical handling procedure of radioactive source material and the typical dosimeter position(on the chest) be respected, the dosimeters calibrated against the broad parallel field appear to provide estimates with acceptable errors for the effective dose of workers exposed to radial broad gamma field around a point source.

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Experimental Study on the Determination of Absorbed dose Index (흡수선량지수결정(吸收線量指數決定)에 관한 실험적(實驗的) 연구(硏究))

  • Jun, Jae-Shik;Rho, Chae-Shik;Ro, Seung-Gy;Ha, Chung-Woo;Yoo, Young-Soo;Lee, Hyun-Duk
    • Journal of Radiation Protection and Research
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    • v.7 no.1
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    • pp.34-48
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    • 1982
  • The prime purpose of this study is to realize an index quantity, absorbed dose index, defined by the ICRU for the characterization of ambient radiation level at any location for the purpose of radiation protection. The experiment has been designed to be carried out in two phases, namely, preliminary and main experiment. In the primary study a 30cm diameter sphere of polyethylene was used, while in the main experiment that of tissue equivalent material was fabricated and used. Both experiments were performed in the gamma-ray fields of $^{137}Cs\;and\;^{60}Co$, and in a neutron beam of thermal column of the TRIGA MARK-II research reactor. In the measurement of gamma-ray absorbed dose TLD-700 $(^{7}LiF)$ chips were used, and for the neutron dose both Au activation foils and TLD chips (TLD-600 $(^{6}LiF)$ and TLD-700 for the discrimination of gamma-ray contribution) were used. Theoretical assessment of the absorbed dose in the sphere phantom has been carried out in accordance with the Ehrlich's idea that deduced on the basis of Burlin's cavity theory in the case of gamma-ray irradiation. For the analysis of neutron dose fluence-KERMA rate conversion method was used. The explanation on the dose assessment is given in detail. Results obtained were numerically and statistically analyzed and the depth dose distributions are presented in the graphic forms with normalized values. In the concluding remarks, the possibility and difficulty of realizing the index quantity, including questions and problems to be solved are mentioned.

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Usefulness Evaluation of Algorithm Conversion Method for Dose Reduction in Brain CT Examination (두부 CT 검사에서 선량감소를 위한 알고리즘 변환방법의 유용성 평가)

  • Kim, Hyeon ju
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.481-487
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    • 2019
  • Based on the scan conditions and algorithms that are generally applied during examinations during head CT examinations, the results of dose reduction through the application of algorithm changes were investigated through experiments. As a result, the dose reduction effect was more meaningful for the change of perfusion than for the tube voltage, and the quality evaluation using the brain phantom was relatively less reduced when the dose was reduced after the application of the Bone algorithm, especially for the application of the Bone algorithm, and the deviation of the mean CT number or Pixel value was measured relatively significantly. In other words, the conditions under which dose was reduced and quality was maintained to reduce the patient's exposure dose and obtain images of the same quality were obtained with the application of the Smooth algorithm and the resulting values of 120 kVp, 160 mA. At this point, doses were reduced by about 28%, and the mean CT number or Pixel value was also measured with relatively little error. If the results are applied to patients who visit the hospital for examination or follow-up after applying various algorithms and follow up scan conditions, the results are considered to be very useful in reducing patient exposure dose.

Anthelminthic Effect of Oxantel Pamoate against Trichocephalus trichiurus Infection (Oxantel pamoate의 편충(鞭虫)에 대한 구충효과(驅虫效果))

  • Lim, J.K.
    • The Korean Journal of Pharmacology
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    • v.10 no.2
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    • pp.25-29
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    • 1974
  • The present clinical trial was performed to evaluate the anthelminthic effect and tolerance of Oxantel pamoate, a new antiwhipworm agent, in the treatment of T. trichiurus infection. Oxantel pamoate oral suspension was administered as a sing1e dose of 10 mg per kg. body weight to a total of 46 T. trichiurus infected cases selected out of 64 positives, by examining 89 fecal specimens collected from the soldiers and in-patients of xx Armed Forces General Hospital. For the evaluation, the negative conversion rate (cure rate) and the egg reduction rate were assessed 22 days after the treatment. The result obtained were as follows: 1. The prevalence rate of T. trichiurus infection in this study was 71.9%, while the mean E.P.G. of 46 treated cases was 126. 2. The egg negative conversion rate was 91.3%, and 98.4% of egg reduction rate was obtained. 3. From the observation of 107 worms expelled during 3 consecutive days after the treatment, it was known that sex ratio of male and female was about 1 : 2 and that average worm burden per capita was 2.3. 4. In all treated cases, the medication was readily accepted and well tolerated. On the hemograms, urinalysis and liver function tests, no significant differences were noted before and after the drug administration. There was also no detectable objective and subjective side effect.

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Effect of the Rosae laevigatae Fructus extract on the nitric oxide synthase activity and antioxidan action in Rat's corpus cavernosum penis (금앵자(金櫻子) 추출물(抽出物)이 음경해선체(陰莖海線體)의Nitric oxide synthase 활성(活性) 및 항산화효과(抗酸化效果)에 미치는 영향(影響))

  • Kim, Kyung-Dong;Jeong, Ji-Cheon
    • The Journal of Internal Korean Medicine
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    • v.19 no.1
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    • pp.452-465
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    • 1998
  • Rosae laevigatae Fructus extract (RLF) was tested for the effects on the urethral nitric oxide synthase (NOS) activity and Antioxidation in streptozotocin (STZ) induced diabetic rats. RLF was treated firstly into samples, and then STZ induced diabetic rats were set with them. In vitro, the urethral NOS activity was not noted but the type O activity and type conversion ratio of xanthine oxidase and the level of urethral lipid peroxide were decreased in the level of Dose of extract prepared from RLF. In vivo, after the extract was administered to the animal model for fifteen days, the urethral NOS activity increased in STZ induced diabetic rats to the level of normal rats. The content of urethral nitrite and glutathione followed by RLF pre-medicating administration, increased as highly as normal group in compare with the group treated with STZ. The type O activity and type conversion ratio of xanthine oxidase and the level of urethral lipid peroxide followed by RLF pre-medicating administration, decreased as lowly as normal group in compare with the group treated with STZ. In conclusion, the extract of RLF will be able to restore erectile dysfunction of STZ induced diabetic rats.

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