• Title/Summary/Keyword: Dosage strength

Search Result 222, Processing Time 0.03 seconds

Flexural Performance of Cement Treated Clay-Sand Mixtures Reinforced with Synthetic Fibers (합성섬유로 보강된 시멘트-점토-모래 혼합토의 휨성능 평가에 관한 연구)

  • Jung, Du-Hwoe;Cho, Baik-Soon;Lee, Yong-Yun
    • Journal of the Korean Geosynthetics Society
    • /
    • v.16 no.1
    • /
    • pp.19-29
    • /
    • 2017
  • The effects of synthetic fibers, cement content, and sand content on the flexural performance of cement-clay-sand mixtures has been evaluated through a flexural performance test with a third-point loading. Beam specimens for the flexural performance test were fabricated with a various amount of cement, sand, and synthetic fibers. Two types of fibers, PVA (Polyvinyl alcohol) and PP (Polypropylene) fibers, were employed in the test. The test results have exhibited that the factors considered in the test have significant effects on the flexural performance of the mixtures in several aspects. The flexural performance of the mixtures has been improved if the mixtures were reinforced with synthetic fibers. The flexural strength and the flexural toughness of the mixtures has been increased as the fiber content was increased. A multiple linear regression analysis has been performed to evaluate the effect of fiber content, cement dosage, and sand content on the flexural performance of the mixtures in terms of flexural strength and flexural toughness. Cement content and sand content were estimated as important factors to have an influence on the first-crack strength and the peak strength whereas the fiber content has the most significant influence on the post-crack behavior. The first-crack strength and the ultimate strength were increased as the cement content and the sand content were increased. As the fiber content was increased, the flexural toughness was increased.

The Effect of Additives on the Mechanical Properties of Rigid Polyurethane (경질 폴리 우레탄의 기계적물성에 미치는 첨가제의 영향)

  • Na, Seok-En;Choi, Hwan-Oh;Lee, Jeon-Kyu;Kim, Si-Young;Ju, Chang-Sik
    • Korean Chemical Engineering Research
    • /
    • v.50 no.5
    • /
    • pp.783-788
    • /
    • 2012
  • Stern tube bearing is a shaft device playing important roles to reduce the friction of axial rotation and to support the weight of shaft. However, because there is no domestic producer of stern tube bering, imported stern tube bearings have many practical problems including prices, delivery and after services. This is why stern tube bearing should be localization. For the purpose of development of polyurethane resin for stern tube bearings, the effect of additives on the hardness, tensile strength and elongation of the polyurethane resin were systematically investigated. For the preliminary researches, depending on the type of curing agent, MOCA type and non-MOCA type polyurethanes were synthesized. Preliminary researches concluded that MOCA type polyurethane resin has more excellent mechanical properties than non-MPCA type for stern tube bearings that Tensile strength and Hardness of non-MOCA type investigated 23 D, 4.3 Mpa. Therefore, MOCA type polyurethane was adapted as base resin of this research. Silica, calcium carbonate and graphite were selected as additives for the enhancement of mechanical properties of polyurethane resin. Effect of the type and the dosage of these additives on the hardness, tensile strength, elongation of the polyurethane resin were experimentally examined. However, addition of calcium carbonate and graphite showed only minor effect on the hardness of the resin. Polyurethane resin with silica showed relatively excellent hardness, tensile strength and improved elongation.

Effects of Caponization and Testosterone on Bone and Blood Parameters of SCWL Male Chickens

  • Chen, Kuo-Lung;Tsay, Shiow-Min;Lo, Dan-Yuan;Kuo, Feng-Jui;Wang, Jiann-Hsiung;Chiou, Peter Wen-Shyg
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.20 no.5
    • /
    • pp.706-710
    • /
    • 2007
  • This study was to investigate the caponization effects on bone characteristics in male chickens, and the optimum testosterone implantation dosage on bone characteristics improvement. Healthy Single Comb White Leghorn cockerels were caponized at 12-wk-old and selected at 16-wk-old for a 10-wk feeding experiment. Fifteen intact male and caponized male chickens (capon) respectively were assigned to trial 1. Ten sham-operated chickens and 40 capons (randomly allocated into four treatments) were implanted with cholesterol (1.62 mm i.d., 3.16 mm o.d., $9.24{\pm}0.36$ mg), low (1 mm i.d., 3 mm o.d., $5.88{\pm}0.23$ mg), medium (1.62 mm i.d., 3.16 mm o.d., $9.81{\pm}0.17$ mg) or high dose (2 mm i.d., 4 mm o.d., $16.7{\pm}0.24$ mg) of testosterone in trial 2. The results from trial 1 showed that the tibia length, relative tibia weight, breaking strength, bending moment and stress in intact males were higher than capons (p<0.05). The blood phosphorus concentration in capons was higher than the intact male chickens (p<0.05). Caponization also resulted in more antrums and osteoclasts within periosteum and cortical bone from histological observation. In trial 2, the adverse impact of caponization on the bone breaking strength, bending moment and stress could be alleviated through medium dose testosterone implantation. It appears that caponization reduced androgen secretion hence influenced the biomechanical characteristics of bone (tibia) and these adverse effects could be alleviated through appropriate dose of testosterone implantation.

Effect of Rice Straw Steaming Time and Mixing Ratio between Acacia mangium Willd Wood and Steamed Rice Straw on the Properties of the Mixed Particleboard

  • Tran, Van Chu;Le, Xuan Phuong
    • Journal of Forest and Environmental Science
    • /
    • v.31 no.2
    • /
    • pp.119-125
    • /
    • 2015
  • This study examined the effects of rice straw steaming time and mixing ratio between rice straw and wood particle on the properties of mixed particle board from Acacia mangium Willd wood and rice straw. Rice straw and Acacia mangium Willd wood were collected in Hanoi, Vietnam. The particle board was three-layer particle board with the structural ratio of 1:3:1. The thickness, density and board size of the particle board were 18 mm, $0.7g/cm^3$, and $800{\times}800{\times}18$ (mm, including trimming), respectively. A resin mixture between commercial Urea-formaldehyde (U-F) adhesive and methylene diphenyl isocyanate (MDI) adhesive was used with a dosage of 12% for the core layer and 14% for the surface layer. In this experimental design, the steaming time for rice straw was 15, 30, 45, 60, and 75 minutes at $100^{\circ}C$. The rice straw-wood mixing ratio was 10, 20, 30, 40, and 50%. The results showed that both mixing ratio and steaming time affect the properties of the particleboard, but the mixing ratio has a stronger impact. A higher mixing ratio and a longer steaming time resulted in a better quality of particleboard. The optimal steaming time for rice straw was 46.12 minutes with the straw-wood mixing ratio of 29.85% with the following characteristics of the particle board: the modulus of rupture (MOR) of 14.64 MPa, internal bond strength (IB) of 0.382 MPa, thickness swelling (TS) of 8.83%, and board density of $0.7-0.7g/cm^3$.

Physicochemical Characterization and In Vivo Evaluation of Thermosensitive Diclofenac Liquid Suppository

  • Yong, Chul-Soon;Choi, Young-Kwon;Kim, Yong-Il;Park, Byung-Joo;Quan, Qi-Zhe;Rhee, Jong-Dal;Kim, Chong-Kook;Choi, Han-Gon
    • Archives of Pharmacal Research
    • /
    • v.26 no.2
    • /
    • pp.162-167
    • /
    • 2003
  • Liquid suppository systems composed of poloxamers and bioadhesive polymers were easy to administer to the anus and mucoadhesive to the rectal tissues without leakage after the dose. However, a liquid suppository containing diclofenac sodium could not be developed using bioadhesive polymers. since the drug was precipitated in this preparation. To develop a liquid suppository system using sodium chloride instead of bioadhesive polymers, the physicochemical properties such as gelation temperature, gel strength and bioadhesive force of various formulations composed of diclofenac sodium, poloxamers and sodium chloride were investigated. Furthermore, the pharmacokinetic study of diclofenac sodium delivered by the liquid suppository was performed. Diclofenac sodium significantly increased the gelation temperature and weakened the gel strength and bioadhesive force, while sodium chloride did the opposite. The liquid suppositories with less than 1.0% of sodium chloride, in which the drug was not precipitated, were inserted into the rectum without difficulty and leakage. Furthermore, liquid suppository gave significantly higher initial plasma concentrations and faster Tmax of diclofenac sodium than did solid suppository, indicating that drug from liquid suppository could be absorbed faster than that from solid one in rats. Our results suggested that a thermosensitive liquid suppository system with sodium chloride and poloxamers was a more physically stable, convenient and effective rectal dosage form for diclofenac sodium.

Formulation and Pharmaceutical Properties of Local Mucoadhesive-Patch Preparation (국소치료용 구강점막패취의 제제설계 및 약제학적 특성)

  • Lee, Gye-Ju;Shu, Hyun-Joo;Lee, Duck-Geun;Park, Jong-Bum;Shin, Kwang-Hyun;Hwang, Sung-Joo
    • YAKHAK HOEJI
    • /
    • v.42 no.2
    • /
    • pp.187-195
    • /
    • 1998
  • In order to ameliorate disadvantages of buccal ointments and mucoadhesive tablets used for the treatment of aphthosis, a thin mucoadhesive patch containing triamcinolone acetoni de was designed and evaluated for the pharmaceutical properties. The adhesive gel layer consisting of Noveon AA-1, hydroxypropylcellulose-M and ethylcellulose N 100, and the protective gel layer of ethylcellulose N 100, Eudragit RSPO and castor oil have been formulated and various properties such as viscosity of drug gel layer, thickness, in vitro adhesion time, adhesive strength, surface pH, content uniformity and drug release are tested. The mean viscosity of drug-containing gel layer was found to increase with increasing amount of Noveon OAA-1 or hydroxypropylcellulose-M. The optimum formulation showed the thickness of 171 ${\mu}$m, surface pH of 4.6, in vitro adhesion time of 8 hours and adhesive strength of 272.7g/sheet. The drug content of each patch was relatively homogeneous with the value of 273${\pm}$6.77g. Drug release study showed that compared to mucoadhesive tablet, the patch showed a faster drug release. Drug release was delayed by hydroxypropylcellulose-M, but not by ethylcellulose N 100. The patches prepared were nonirritant and the muco adhesion was better than the commercial product (AftachR) on the market. Based on these results, this mucoadhesive patch is expected to be an effective dosage form for the treatment of aphthosis.

  • PDF

A comprehensive review of the Fenton-based approaches focusing on landfill leachate treatment

  • Hussain, Mujtaba;Mahtab, Mohd Salim;Farooqi, Izharul Haq
    • Advances in environmental research
    • /
    • v.10 no.1
    • /
    • pp.59-86
    • /
    • 2021
  • Landfilling is the most commonly adopted method for a large quantity of waste disposal. But, the main concern related to landfills is the generation of leachate. The leachate is high strength wastewater that is usually characterized by the presence of high molecular recalcitrant organics. Several conventional methods are adopted for leachate treatment. However, these methods are only suitable for young leachate, having high biodegradability and low toxicity levels. The mature and stabilized leachate needs advanced technologies for its effective treatment. Advanced oxidation processes (AOPs) are very suitable for such complex wastewater treatment as reported in the literature. After going through the literature survey, it can be concluded that Fenton-based approaches are effective for the treatment of various high/low strength wastewaters treatment. The applications of the Fenton-based approaches are widely adopted and well recognized due to their simplicity, cost-effectiveness, and reliability for the reduction of high chemical oxygen demand (COD) as reported in several studies. Besides, the process is relatively economical due to fewer chemical, non-sophisticated instruments, and low energy requirements. In this review, the conventional and advanced Fenton's approaches are explained with their detailed reaction mechanisms and applications for landfill leachate treatment. The effect of influencing factors like pH, the dosage of chemicals, nature of reaction matrix, and reagent ratio on the treatment efficiencies are also emphasized. Furthermore, the discussion regarding the reduction of chemical oxygen demand (COD) and color, increase in biodegradability, removal of humic acids from leachate, combined processes, and the pre/post-treatment options are highlighted. The scope of future studies is summarized to attain sustainable solutions for restrictions associated with these methods for effective leachate treatment.

Properties of Shrinkage in Concrete Incorporating Shrinkage Reducing Agent and Expansive Additive (수축저감제와 팽창재를 병용 치환한 콘크리트의 수축 특성)

  • 김광화;문학룡;심영태;이병상;정용희;한천구
    • Proceedings of the Korean Institute of Building Construction Conference
    • /
    • 2004.05a
    • /
    • pp.61-64
    • /
    • 2004
  • This study is to investigate the engineering and shrinkage properties of concrete incorporating shrinkage reducing agent(SRA) and expansive additive(EA) in order to reduce shrinkage of concrete. According to results, as for the properties of fresh concrete, increase in, SRA and EA content leads to reduce the fluidity but to increase the air content, and as for setting time, there is little difference. For strength properties, it decreased with an increase in SRA dosage and increased up to 5% of EA content. For the properties of drying shrinkage, it shows decline tendency with an increase in SRA and EA content reiteratively. It alto reduces significantly with the combination of SRA-EA systems due to the combined effect of the admixture. In the scope of this paper, it is found that the use of SRA with 0.5% and EA with 5% has optimum effects on the various properties of concrete. And under the combination of SRA and EA, it can reduce drying shrinkage about 37%.

  • PDF

Effect of fibers and welded-wire reinforcements on the diaphragm behavior of composite deck slabs

  • Altoubat, Salah;Ousmane, Hisseine;Barakat, Samer
    • Steel and Composite Structures
    • /
    • v.19 no.1
    • /
    • pp.153-171
    • /
    • 2015
  • Twelve large-scale composite deck slabs were instrumented and tested in a cantilever diaphragm configuration to assess the effect of fibers and welded wire mesh (WWM) on the in-plane shear capacity of composite deck slabs. The slabs were constructed with reentrant decking profile and reinforced with different types and dosages of secondary reinforcements: Conventional welded wire mesh (A142 and A98); synthetic macro-fibers (dosages of $3kg/m^3$ and $5.3kg/m^3$); and hooked-end steel fibers with a dosage of $15kg/m^3$. The deck orientation relative to the main beam (strong and weak) was also considered in this study. Fibers and WWM were found efficient in distributing the applied load to the whole matrix, inducing multiple cracking, thereby enhancing the strength and ductility of composite deck slabs. The test results indicate that fibers increased the slab's ultimate in-plane shear capacity by up to 29% and 50% in the strong and weak directions, respectively. WWM increased the ultimate in-plane shear capacity by up to 19% in the strong direction and 9% in the weak direction. The results suggest that discrete fibers can provide comparable diaphragm behavior as that with the conventional WWM.

The Effect of Hydrogen Peroxide Bleaching on the Properties of Hardwood Kraft Pulp Absorbed with Birchwood Xylan

  • Li, Lizi;Lee, Sang-Hoon;Lee, Hak-Lae
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
    • /
    • 2010.04a
    • /
    • pp.195-206
    • /
    • 2010
  • Xylan can be applied to improve the strength properties of paper; however the optical properties, such as brightness, are decreased significantly. To solve that problem, an applicable bleaching process is therefore desired. The aim of this research was to investigate the impact of hydrogen peroxide bleaching on hardwood kraft pulp pretreated with birchwood xylan by measuring optical properties (whiteness, brightness, opacity) as well as physical properties (tensile index, tearing index, bulk) of handsheets made from the bleached pulp. Hydrogen peroxide bleaching, as a kind of totally chlorine free (TCF) bleaching method, is quite important industrially for chemical pulp. In our work, the process variables of peroxide bleaching including bleaching temperature, time, initial pH and $MgSO_4$ dosage were studied. The results showed that both good mechanical properties and optical properties could be achieved when the operating parameters were controlled properly and therefore hydrogen peroxide bleaching was proved to be a suitable method for bleaching hardwood kraft pulp with adsorption of birchwood xylan.

  • PDF