• 제목/요약/키워드: Dos

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노즐 막힘이 미세 오리피스형 다단 임팩터의 입자 채취 성능에 미치는 영향 (Effect of Particle Clogging in Orifices on the Particle Collection Efficiency of a Micro-Orifice Impactor)

  • 지준호;배귀남;황정호
    • 대한기계학회논문집B
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    • 제27권2호
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    • pp.197-205
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    • 2003
  • A cascade impactor is a multistage impaction device used to separate airborne particles into aerodynamic size classes. A micro-orifice impactor uses micro-orifice nozzles to extend the cut sizes of the lower stages to as small as 0.05 ${\mu}{\textrm}{m}$ in diameter without resorting to low pressures or creating excessive pressure drops across the impactor stages. In this work, the phenomenon of particle clogging in micro-orifice nozzles was experimentally investigated for a commercial micro-orifice uniform deposit impactor (MOUDI). It was observed, using an optical microscope, that the micro-orifice nozzles of the final stages were partially clogged due to particle deposition during the aerosol sampling. Therefore the pressure drops across the nozzles were higher than the nominal values given by the manufacturer. To examine the effect of particle clogging in micro-orifice nozzles, the particle collection efficiency of the MOUDI was evaluated using an electrical method for fine particles with diameters in the range of 0.1-0.6 ${\mu}{\textrm}{m}$. The monodisperse liquid dioctyl sebacate (DOS) particles were used as test aerosols. A faraday cage was employed to measure the low-level current of the charged particles upstream and downstream of each stage. It was found that the collection efficiency curves shifted to correspond to smaller orifice sizes, and the 50-% cutoff sizes were much smaller than those given by the manufacturer for the three stages with nozzles less than 400 ${\mu}{\textrm}{m}$ in diameter.

Correlation between Sestrin-2 and PERK Signaling in Matured Porcine Oocytes according to ER-stress during In Vitro Maturation

  • Park, Hyo-Jin;Kim, In-Su;Kim, Jin-Woo;Yang, Seul-Gi;Kim, Min-Ji;Koo, Deog-Bon
    • 한국동물생명공학회지
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    • 제34권3호
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    • pp.212-221
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    • 2019
  • Sestrin-2 (SESN2) as a stress-metabolic protein is known for its anti-oxidative effects as a downstream factor of PERK pathways in mammalian cells. However, the expression patterns of SESN2 in conjunction with the UPR signaling against to ER stress on porcine oocyte maturation in vitro, have not been reported. Therefore, we confirmed the expression pattern of SESN2 protein, for which to examine the relationship between PERK signaling and SESN2 in porcine oocyte during IVM. We investigated the SESN2 expression patterns using Western blot analysis in denuded oocytes (DOs), cumulus cells (CCs), and cumulus-oocyte complexes (COCs) at 22 and 44 h of IVM. As expected, the SESN2 protein level significantly increased (p < 0.01) in porcine COCs during 44 h of IVM. We investigated the meiotic maturation after applying ER stress inhibitor in various concentration (50, 100 and 200 μM) of tauroursodeoxycholic acid (TUDCA). We confirmed significant increase (p < 0.05) of meiotic maturation rate in TUDCA 200 μM treated COCs for 44 h of IVM. Finally, we confirmed the protein level of SESN2 and meiotic maturation via regulating ER-stress by only tunicamycin (Tm), only TUDCA, and Tm + TUDCA treatment in porcine COCs. As a result, treatment of the TUDCA following Tm pre-treatment reduced SESN2 protein level in porcine COCs. In addition, SESN2 protein level significantly reduced in only TUDCA treated porcine COCs. Our results suggest that the SESN2 expression is related to the stress mediator response to ER stress through the PERK signaling pathways in porcine oocyte maturation.

Influence of Toxoplasma gondii Acute Infection on Cholinesterase Activities of Wistar Rats

  • Tonin, Alexandre Alberto;da Silva, Aleksandro Schafer;Thorstenberg, Maria Luiza;Castilhos, Livia Gelain;Franca, Raqueli Teresinha;Leal, Daniela Bitencourt Rosa;Duarte, Marta Maria Medeiros Frescura;Vogel, Fernanda Silveira Flores;de La Rue, Mario L.;dos Anjos Lopes, Sonia Terezinha
    • Parasites, Hosts and Diseases
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    • 제51권4호
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    • pp.421-426
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    • 2013
  • Several studies have shown the mechanisms and importance of immune responses against Toxoplasma gondii infection and the notable role of cholinesterases in inflammatory reactions. However, the association between those factors has not yet been investigated. Therefore, the aim of this study was to evaluate the acetylcholinesterase (AChE) activity in blood and lymphocytes and the activity of butyrylcholinesterase (BChE) in serum of rats experimentally infected with T. gondii during the acute phase of infection. For that, an in vivo study was performed with evaluations of AChE and BChE activities on days 5 and 10 post-infection (PI). The activity of AChE in blood was increased on day 5 PI, while in lymphocytes its activity was enhanced on days 5 and 10 PI (P<0.05). No significant difference was observed between groups regarding to the activity of BChE in serum. A positive (P<0.01) correlation was observed between AChE activity and number of lymphocytes. The role of AChE as an inflammatory marker is well known in different pathologies; thus, our results lead to the hypothesis that AChE has an important role in modulation of early immune responses against T. gondii infection.

분산 설계 환경 하에서 XML과 XSLT를 이용한 레거시 기어 설계 시스템의 확장 (Extension of Legacy Gear Design Systems Using XML and XSLT in a Distributed Design Environment)

  • 정태형;박승현
    • 한국공작기계학회논문집
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    • 제11권4호
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    • pp.19-25
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    • 2002
  • As computer-related technologies have been developed, legacy design systems have not been appropriate far new computing environment. It is necessary that most of them are either modified or newly developed. However, these activities require quite much amount of cost and time. This paper presents a method of extending legacy design systems to the internet without any modification using XML and XSLT. We have been extended legacy systems in the two viewpoints. First, an XML document has been defined to present the input information of a legacy system which is executed on the consol environment - MS DOS, for example. Also, an XSLT document has been generated to transform an XML document to the input document of the legacy system An XML document is transformed to the input document by XSLT processor according to the transformation rules defined in the XSLT document. This technique to generate input documents is independent to the platform type and facilitates to link legacy systems to other systems. Second, a legacy system controller has been made to control a legacy system and developed a web service to extend it and its controller. The legacy system controller operates it automatically. The web service provides its functions to other systems via internet. We have applied the developed methodologies to the legacy gear design system 조ich calculates AGMA gear rating md made AGMA gem rating web service.

종합 교통수요 예측모형 "사통팔달:윈도우즈"의 개발 (Development of a Transportation Demand Analysis Model ${\ulcorner}$AllWayS-Windows Version${\lrcorner}$)

  • 심대영;조중래;김동효
    • 대한교통학회지
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    • 제22권2호
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    • pp.19-26
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    • 2004
  • 사통팔달(AWS:AllWayS)은 교통계획의 중요성이 날로 부각되는 추세에서 네트워크 편집 및 데이터베이스 분석 기능을 갖춘 국내에서 최초로 개발된 종합적인 교통수요 예측모형이다. 과거에 일부 개별적인 모형의 수행을 위해 개별 기능의 수행을 위한 수요예측모형들이 국내에서 개발되어 사용되어온 바 있으나, 사통팔달 모형은 과거동안 축적된 교통계획 및 전산기술에 대한 이론적, 경험적 성과들을 바탕으로 국내 실정에 적합한 전통적인 4단계 수요예측과정에 대해 전체적으로 수행이 가능하도록 체계화함으로써 기존 외국의 교통계획모형들이 비판없이 사용되고 있는 국내 현실에서 본 모형의 유용성이 있다고 사료된다. 아울러 교통수요 예측을 위해 필요한 가로, 대중교통 등의 교통 네트워크 자료의 작성 기능을 모형의 내에서 갖추고 있으며 모형의 수행에 필요한 모든 자료들을 데이터베이스화함으로 대상 분석 시나리오에 대해 종합적이고 일관적인 수요예측 과정을 수행할 수 있도록 모형을 개발하였다.

PC용 중소형 S/W개발을 위한 graphic user interface tool kit

  • 신하용;홍태화
    • 한국경영과학회:학술대회논문집
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    • 대한산업공학회/한국경영과학회 1992년도 춘계공동학술대회 발표논문 및 초록집; 울산대학교, 울산; 01월 02일 May 1992
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    • pp.524-531
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    • 1992
  • S/W의 구성은 기능을 실제로 수행하는 계산처리부와 사용자와 정보를 주고받는 User Interface부로 크게 나누어 볼 수 있다. 대부분의 S/W는 그 기능의 충실도와 아울러 편리한 사용법이 잘 어울려야 제역할을 할 수 있다. 따라서 편리한 User Interface를 만드는 일은 훌륭한 기능을 제공하는 것과 마찬가지로 S/W 개발자들이 지향해야 할 목표중 하나라 하겠다. 그러나 편리한 User Interface를 만드는 일은 전체 시스템개발 기간중 상당한 부분을 차지한다. 특히 CAD/CAM관련 S/W와 같이 사용자와 정보를 Graphic으로 주고받는 경우에는 User Interface의 구성이 더욱 더 어려워지며, 개발기간중 User Interace가 차지하는 비중은 더욱 커지게 된다. GUI는 최근들어 상당히 각광을 받고 있는 분야이며, 상당수의 GUI가 개발되어 있고, 이중 Unix용의 X-Window MS-DOS용의 MS-WINDOWS 3.0이 널리 사용되고 있다. 그러나 이러한 Window System들은 매우 다양한 기능을 제공하고 있음에도 불구하고, GUI자체의 덩치가 매우크고, S/W개발자가 익혀야하는 내용이 너무 복잡하여, 중/소형의 S/W개발에 사용하기에는 적합하지 않다. 본 연구에서는 GUI(Graphic User Interface)부분을 계산처리부와 완전분리하여, 범용성있는 개발용 Tool Kit을 구성함으로써 S/W개발자는 계산처리부만을 만들면되는 방안을 제시하고 있다. GS-GUI는 Menu처리부, Mouse/Keyboard입력처리부, Text/Graphic출력처리부로 나뉘어진다. Menu처리부는 Menu File로 주어지는 Menu Tree를 Pop-Up형태로 보여주며 User가 Menu를 선택할 수 있도록하며 선택된 Menu Item에 대한 Action Code를 계산처리부로 넘겨준다. 입력처리부에서는 Mouse와 Keyboard 어느것으로나 입력이 가능하도록 해준다. 출력처리부에서는 Action Code에 따라 계산처리부에서 계산된 결과를 화면에 보여주기 위한 각종 2D/3D Graphic Routine들이 포함되어있어 계산처리부에서 불러쓰도록 되어있다.

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FREEZING POINT DEPRESSION OF RAW GOAT'S MILK FROM THE REGION OF GOIÂNIA, BRAZIL

  • de Sousa, J.T.;Dias, M.J.;Tanezini, C.A.;D'Alessandro, W.T.;de Olineira, B.C.;de Melo Rocha, J.;dos Santos Pontes, I.
    • Asian-Australasian Journal of Animal Sciences
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    • 제6권4호
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    • pp.555-559
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    • 1993
  • Studies at freezing point depression (FPD) for goat milk are described in this paper. The 432 samples of raw goat milk collected in a period of two years and analysed by the use of an electronic cryoscope gave a mean value of FPD: $-0.565{\pm}0.01^{\circ}C$. Statistical significant differences were found between the morning and evening milk. The evening milk showed better quality considering the lactose and others dissolved solutes. Among the Brown, Saanen and Anglo-nubian goats, the greatest increase in FPD, occurred in the Anglo-nubian breed. The statistical analysis revealed a significant breed difference (p<0.05), when climate variation was observed. The superior and inferior values found to the FPD of the caprine milk (-0.545 to $-0.585^{\circ}C$), is important in establishing regional rules, to improve the quality control criteria and legal interpretation of standards found in the pertinent legislation. The results are also important to improve herd management so that one can increase the animal production which will affect the technological composition, and the nutritional characteristics of the resultant products.

Pelleting in Associated with Sodium Monensin Increases the Conjugated Linoleic Acids Concentration in the Milk of Dairy Cows Fed Canola Seeds

  • De Marchi, Francilaine Eloise;Romero, Jakeline Vieira;Damasceno, Julio Cesar;Grande, Paula Adriana;Zeoula, Lucia Maria;dos Santos, Geraldo Tadeu
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권8호
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    • pp.1095-1104
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    • 2015
  • To evaluate the effects of the pelleting and the addition of sodium monensin on production, the chemical and lipid composition of milk and butter physical characteristics, 4 Holstein dairy cows (135 days of lactation) with an average milk production of 14.7 kg/d, were supplemented with a concentrate containing ground canola seeds. The cows were assigned to a $4{\times}4$ Latin square design with a $2{\times}2$ factorial arrangement of treatments: i) ground maize, soybean meal, mineral and vitamin supplements, and ground canola seeds (CG); ii) CG concentrate with 31.5 mg of monensin added per kg of dry matter (DM); iii) CG pelleted concentrate; iv) CG concentrate with monensin addition pelleted. There was no difference in milk production and composition. The addition of monensin increased milk concentration of polyunsaturated fatty acids (PUFA), the PUFA/saturated fatty acids (SFA) ratio, and omega 6. The pelleting increased the concentration of monounsaturated fatty acids, the PUFA/SFA ratio, and the omega 6/omega 3 ratio, but decreased the concentration of SFA. The association between pelleting and the addition of monensin increased the concentration of conjugated linoleic acids by 46.9%. The physical characteristics of butter were not affected by the evaluated diets. We concluded that the concentrate with 31.5 mg of monensin added per kg DM basis combined with the pelleting improves the lipid composition of milk from Holstein cows that are on pasture and supplemented with ground canola seeds, without changing the production, milk composition, and spreadability of butter.

Residual frying oil in the diets of sheep: intake, digestibility, nitrogen balance and ruminal parameters

  • Peixoto, Eduardo Lucas Terra;Mizubuti, Ivone Yurika;Ribeiro, Edson Luiz de Azambuja;Moura, Elizabeth dos Santos;Pereira, Elzania Sales;Prado, Odimari Pricila Pires do;Carvalho, Larissa Nobrega de;Pires, Kassia Amariz
    • Asian-Australasian Journal of Animal Sciences
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    • 제30권1호
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    • pp.51-56
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    • 2017
  • Objective: The objective of this study was to evaluate the intake and nutrient digestibility, nitrogen balance and ruminal ammonia nitrogen in lambs of diets containing different levels of residual frying oil. Methods: Levels of 0, 20, 40, 60, and 80 g/kg dry matter (DM) base of residual frying oil in the diets of lambs were evaluated. Five castrated lambs with initial body weights of $36.8{\pm}3.3kg$, distributed in a Latin square ($5{\times}5$) design, were used. Results: There was a decreasing linear effect on the intake of DM, organic matter (OM), crude protein (CP), neutral detergent fiber (NDF), total carbohydrates (TCH), and nonfibrous carbohydrates (NFC). There was an increased linear intake of ether extract (EE). The apparent digestibility of DM, OM, CP, NDF, TCH, and NFC, as well as urine nitrogen excretion, nitrogen balance and ruminal parameters, were not influenced by different levels of residual frying oil in the diet. EE digestibility presented a crescent linear effect. Conclusion: It can be concluded that the addition of residual frying oil to the diets of sheep can affect nutrient intake without affecting the digestibility of most nutrients (with the exception of EE), nitrogen balance and ruminal ammonia nitrogen concentration.

iPhone7을 중심으로 한 아이콘 디자인에 대한 연구 (A Study on Mobile Icon Design of iPhone7)

  • 김정희
    • 만화애니메이션 연구
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    • 통권34호
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    • pp.367-386
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    • 2014
  • 과학기술의 눈부신 발전은 디지털 기기의 콘텐츠 및 디자인의 다양성과 변화로 이어졌으며 여기에서 파생되는 UI, UX, GUI 디자인은 세분화된 디지털 디자인의 창조 및 발전으로 거듭났다. 이런 다양한 디지털 매체의 디자인은 도스 이후의 윈도우의 시작과 함께 생겨났으며 이는 마우스라는 혁신적인 도구의 개발로 인해 가능했다. 이러한 환경 안의 디지털 매체 디자인의 중심에는 모든 콘텐츠 및 버튼, 입구를 상징하는 아이콘이 있으며 모바일, 앱, 윈도우환경에서 필수요소로 자리 잡고 있다, 이러한 아이콘은 윈도우 초기 시절부터 다양한 발전을 거듭하였으며 이는 디지털 과학기술의 발전과 함께 하였다. 디자인 트렌드분석은 스큐어모피즘에서 부터 플랫된 형태 그리고 미니멀리즘으로 되돌아오기까지의 아이콘의 디자인의 변천을 분석한다. 분석 범위는 트렌드와 기기의 성능에 민감한 모바일을 대상으로 분석하며 Kress's grammar of visual design의 분석틀을 기본으로 한다. 특히 iPhone의 IOS7디자인이 애플의 대표 디자인 트렌드인 스큐어모피즘을 접고 미니멀리즘, 플렛 디자인을 채택해 큰 변화를 겪는 현 시점에서 모바일 앱시장의 GUI 디자인 기초 동향 파악 자료로 활용되는데 도움이 되고자 한다.