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검색결과 426건 처리시간 0.026초

코발트-60 원격치료기를 이용한 전신 방사선 조사에서 선량율의 차이에 따른 급성효과 (Acute Response to Co-60 Total Body Irradiation (TBI) With 600 cGy at 3 Different Does Rates in the Mice)

  • 강철훈;김성규;신세원;김명세
    • Radiation Oncology Journal
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    • 제8권2호
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    • pp.151-154
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    • 1990
  • 영남대학교 의과대학 치료방사선과학교실에서는 코발트-60원격치료기를 이용하여 80마리의 ICR 백서를 대상으로 서로다른 세가지 선량율로 600 cGy 단일조사를 시행한뒤 9주일동안 체중 및 말초혈액소견의 변화를 추적조사한 결과 다음과 같은 성적을 얻었다. 1. 체중변화는 선량율에 상관없이 조사 1주일부터 감소하여 6-7주일부터 치료전의 체중까지 회복 되었다. 2. 혈색소의 변화는 전 추적조사기간에 걸쳐 변화가 없었다. 3. 말초 혈액내의 백혈구의 총수는 조사 1주일부터 3주일까지 형태학적 구분이 안되는 수개의 세포만이 인지되었고 4주일부터 호중구의 회복이 임파구에 비해서 현저하였으며 8-9주일부터 조사전의 상태로 완전 회복되었다. 이상의 결과를 토대로 보다 다양한 실험을 거친후 저선량율 전신조사의 가장 큰 단점인 장시간의 조사로 인한 기계의 무리와 환자 위치고정의 해결을 위하여 분당 선량율을 15 cGy까지 올릴 수 있으리라 기대된다.

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접속부 궤도 성토재료의 함수특성곡선을 이용한 포화도 분포 산정 (Assessing Distribution of Degree of Saturation for Track Transition Zone Using Soil Water Characteristic Curve)

  • 최찬용;이정민;권혁민;오정호
    • 대한토목학회논문집
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    • 제35권2호
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    • pp.515-524
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    • 2015
  • 최근 궤도 접속부에서의 부등침하 및 궤도틀림으로 잦은 유지보수 및 열차운영에 지장을 초래하는 경우가 많아지고 있다. 이는 주로 궤도 접속부 시공에 사용되는 다양한 성토재료의 강우나 동결융해 같은 환경적 인자에 의한 역학적 물성들의 변화에 기인한 것으로, 본 연구에서는 궤도 접속부 성토재료에 대한 함수특성곡선을 산정하고 강우 시 포화도 변화 추이를 알아보고자 침투해석을 수행 하였다. 필터페이퍼를 이용하여 다짐 성토의 함수특성곡선을 성공적으로 산정할 수 있었고, 함수특성곡선 데이터를 이용한 강우 시 침투해석을 수행한 결과 궤도 접속부 성토재료의 포화도 분포는 강우강도, 뒤채움재 경사, 성토 및 절토 여부, 그리고 함수특성곡선에 큰 영향을 받는 것을 확인 하였다.

Piglets' Surface Temperature Change at Different Weights at Birth

  • Caldara, Fabiana Ribeiro;dos Santos, Luan Sousa;Machado, Sivanilza Teixeira;Moi, Marta;de Alencar Naas, Irenilza;Foppa, Luciana;Garcia, Rodrigo Garofallo;de Kassia Silva dos Santos, Rita
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권3호
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    • pp.431-438
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    • 2014
  • The study was carried out in order to verify the effects of piglets' weight at birth on their surface temperature change (ST) after birth, and its relationship with ingestion time of colostrum. Piglets from four different sows were weighed at birth and divided into a totally randomized design with three treatments according to birth weight (PBW): T1 - less than 1.00 kg, T2 - 1.00 to 1.39 kg, and T3 - higher than or equal to 1.40 kg. The time spent for the first colostrum ingestion was recorded (TFS). Images of piglets' surface by thermal imaging camera were recorded at birth (STB) and 15, 30, 45, 60, and 120 min after birth. The air temperature and relative humidity were recorded every 30 min and the indexes of temperature and humidity (THI) were calculated. A ST drop after 15 min from birth was observed, increasing again after sixty minutes. Positive correlations were found between the PBW and the ST at 30 and 45 min after birth. The PBW was negatively correlated with the TFS. The THI showed high negative correlations (-0.824 and -0.815) with STB and after 15 min from birth. The piglet's surface temperature at birth was positively correlated with temperature thereof to 15 min, influencing therefore the temperatures in the interval of 45 to 120 min. The birth weight contributes significantly to postnatal hypothermia and consequently to the time it takes for piglets ingest colostrum, requiring special attention to those of low birth weight.

현무암 재봉사의 연속식 테프론 코팅 공정 (Continuous PTFE Coating Process on Basalt Sewing Thread)

  • 이수
    • 한국응용과학기술학회지
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    • 제31권2호
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    • pp.183-189
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    • 2014
  • 내화성 및 내화학성이 우수한 현무암사의 표면에 회분식 방법에 의한 테프론 코팅 연구의 결과를 토대로 연속식 코팅 공정 인자를 도출하기 위한 연구를 수행하였다. 현무암사를 7,5 wt% 트리에톡시트리플루오로실란(TMTFPS)으로 연속적으로 전처리 한 후, 침투제로 0.25 wt% bis(2-ethylhexyl)sulfo succinate (DOS-Na)가 함유된 20 wt% 테프론 수분산액으로 딥 코팅한 후 2 m의 $120^{\circ}C$ 건조 챔버에서 12 m/mim의 속도로 건조한 후 2 m의 $380^{\circ}C$ 소성 챔버에서 40초간 소성하여 최종 $3.4g_f/D$의 인장 강도와 $2.3g_f/D$의 루프강도를 가지는 테프론이 코팅된 고내열 재봉사용 현무암사를 제조하였다.

Nutritional and performance viability of cactus Opuntia-based diets with different concentrate levels for Girolando lactating dairy cows

  • Inacio, Jonas Gomes;da Conceicao, Maria Gabriela;dos Santos, Djalma Cordeiro;de Oliveira, Julio Cesar Vieira;Chagas, Juana Catarina Cariri;de Oliveira Moraes, Glaucia Sabrine;dos Santos Silva, Evannielly Thuanny;de Andrade Ferreira, Marcelo
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권1호
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    • pp.35-43
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    • 2020
  • Objective: The aim of this research was to evaluate the effect of different concentrate levels in diets based on cactus Opuntia Stricta (Haw.) Haw cladodes on the performance of lactating Girolando cows. Methods: The experiment involved 10 Girolando multiparous dairy cows at 512.6 kg of body weight (BW) and producing 13.2 kg milk/d, allocated into two 5×5 Latin squares. The experimental treatments consisted of control diet composed by cactus Nopalea cochenillifera. Salm-Dyck. cladodes (Nopalea), forage sorghum silage and concentrate at 20% on dry matter (DM) basis, and four concentrate levels diets (20%, 24%, 28%, and 32%) plus cactus Opuntia stricta (Haw.) Haw. cladodes (Opuntia) and forage sorghum silage. Results: Regarding cows fed control diet, the nutrients intake were greater than for cows fed with cactus Opuntia and concentrate. Regarding concentrate levels, intakes of DM, organic matter (OM), crude protein (CP), non-fiber carbohydrates (NFC), and total digestible nutrients of cows increased linearly. Organic matter, CP, and NDF digestibilities were similar in between to control diet and cactus Opuntia-based diets. The digestibility of NFC increased linearly when the concentrate was inserted. The N balance was the same for control diet and cactus Opuntia-based diets, irrespective the concentrate levels. Conclusion: For cows producing 14 kg/d with 3.5% of fat, it is recommended 32% of concentrate to be included in cactus Opuntia-based diets, and the increase in concentrate level promotes a linear increase in milk yield.

A New Salt-Tolerant Thermostable Cellulase from a Marine Bacillus sp. Strain

  • dos Santos, Yago Queiroz;de Veras, Bruno Oliveira;de Franca, Anderson Felipe Jacome;Gorlach-Lira, Krystyna;Velasques, Jannaina;Migliolo, Ludovico;dos Santos, Elizeu Antunes
    • Journal of Microbiology and Biotechnology
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    • 제28권7호
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    • pp.1078-1085
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    • 2018
  • A salt-tolerant cellulase secreted by a marine Bacillus sp. SR22 strain with wide resistance to temperature and pH was purified and characterized. Its approximate mass was 37 kDa. The endoglucanase, named as Bc22Cel, was purified by ammonium sulfate precipitation, gel filtration chromatography, and extraction from the gel after non-reducing sodium dodecyl sufate-polyacrylamide gel electrophoresis. The optimal pH value and temperature of Bc22Cel were 6.5 and $60^{\circ}C$, respectively. The purified Bc22Cel showed a considerable halophilic property, being able to maintain more than 70% of residual activity even when pre-incubated with 1.5 M NaCl for 1 h. Kinetic analysis of the purified enzyme showed the $K_m$ and $V_{max}$ to be 0.704 mg/ml and $29.85{\mu}mol{\cdot}ml^{-1}{\cdot}min^{-1}$, respectively. Taken together, the present data indicate Bc22Cel as a potential and useful candidate for industrial applications, such as the bioconversion of sugarcane bagasse to its derivatives.

RNA Polymerase II Inhibitor, ${\alpha}$-Amanitin, Affects Gene Expression for Gap Junctions and Metabolic Capabilities of Cumulus Cells, but Not Oocyte, during In Vitro Mouse Oocyte Maturation

  • Park, Min-Woo;Lee, Hyun-Seo;Kim, Eun-Young;Lee, Kyung-Ah
    • 한국발생생물학회지:발생과생식
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    • 제17권1호
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    • pp.63-72
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    • 2013
  • A specific inhibitor of RNA polymerase II, ${\alpha}$-amanitin is broadly used to block transcriptional activities in cells. Previous studies showed that ${\alpha}$-amanitin affects in vitro maturation of cumulus-oocyte-complex (COC). In this study, we evaluated the target of ${\alpha}$-amanitin, and whether it affects oocytes or cumulus cells (CCs), or both. We treated ${\alpha}$-amanitin with different time period during in vitro culture of denuded oocytes (DOs) or COCs in comparison, and observed the changes in morphology and maturation status. Although DOs did not show any change in morphology and maturation rates with ${\alpha}$-amanitin treatment, oocytes from COCs were arrested at metaphase I (MI) stage and CCs were more scattered than control groups. To discover causes of meiotic arrest and scattering of CCs, we focused on changes of cumulus expansion, gap junctions, and cellular metabolism which to be the important factors for the successful in vitro maturation of COCs. Expression of genes for cumulus expansion markers (Ptx3, Has2, and Tnfaip6) and gap junctional proteins (Gja1, Gja4, and Gjc1) decreased in ${\alpha}$-amanitin-treated CCs. However, these changes were not observed in oocytes. In addition, expression of genes related to metabolism (Prps1, Rpe, Rpia, Taldo1, and Tkt) decreased in ${\alpha}$-amanitin-treated CCs but not in oocytes. Therefore, we concluded that the transcriptional activities of CCs for supporting suitable transcripts, especially for its metabolic activities and formation of gap junctions among CCs as well as with oocytes, are important for oocytes maturation in COCs.

데이터베이스와 응용프로그램 사이의 인터페이스 설계 및 구현 (Design and Implementation of Interface between the Database and the Application Program)

  • 정인숙;이창섭;조충호
    • 대한조선학회논문집
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    • 제34권4호
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    • pp.139-147
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    • 1997
  • DOS 환경하에서 개발된 기존의 대부분의 응용프로그램들은 ASCII 형식의 파일을 직접 읽고 씀으로써 외부 세계와 정보를 교환한다. 수많은 단위 모듈로 이루어지는 종합적인 패키지는 모듈 각자의 입출력뿐아니라 모듈 사이의 빈번한 자료교환을 수행하여야 하므로, 모듈의 수가 증가할수록 ASCII 파일을 통한 입출력은 비효율적이고 정확성도 결여된다. 본 논문에서는 용용프로그램이 필요로 하는 모든 정보를 데이터베이스에 저장하고, 패키지의 각 모듈이 데이터베이스와 직접 정보를 교환할 수 있는 인터페이스를 설계하고 이를 실제 구현하는 과정을 보이고 있다. 개발된 인터페이스를 기존의 프로펠러 설계-해석 시스템에 적용하여 데이터베이스와의 정보교류가 원활히 수행되고 있음을 보였다. 이상을 Unix 환경하의 워크스테이션이 아닌 Windows95 환경하의 개인용/휴대용 컴퓨터에서 구현함으로써 프로펠러의 설계-해석을 시간적 공간적 제약없이 수행할 수 있음을 보였다.

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Assessment of the anterior loop of the mandibular canal: A study using cone-beam computed tomography

  • Nascimento, Eduarda Helena Leandro do;Pontual, Maria Luiza dos Anjos;Pontual, Andrea dos Anjos;Perez, Danyel Elias da Cruz;Figueiroa, Jose Natal;Frazao, Marco Antonio Gomes;Ramos-Perez, Flavia Maria de Moraes
    • Imaging Science in Dentistry
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    • 제46권2호
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    • pp.69-75
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    • 2016
  • Purpose: Sufficient area in the interforaminal region is required for dental implant placement, and the anterior loop of the mandibular canal is located within the limits of this area. The aim of this study was to evaluate the prevalence and extent of the anterior loop in a Brazilian sample population using cone-beam computed tomography (CBCT). Materials and Methods: CBCT images from 250 patients (500 hemimandibles) obtained for various clinical indications were randomly selected and evaluated to determine the presence and length of the anterior loop. The length of the anterior loop was then compared based on gender, age, and the side of the mandible. The data were analyzed using the Pearson chi-square test and linear regression analysis. Results: An anterior loop was identified in 41.6% of the cases, and its length ranged from 0.25 mm to 4.00 mm (mean, $1.1{\pm}0.8mm$). The loop had a greater mean length and was significantly more prevalent in males (p=0.014). No significant differences were found between the right and left sides regarding length (p=0.696) or prevalence (p=0.650). Conclusion: In this study, a high prevalence of the anterior loop of the mandibular canal was found, and although its length varied greatly, in most cases it was less than 1 mm long. Although this is a prevalent anatomical variation, safety limits for the placement of implants in this region cannot be established before an accurate evaluation using imaging techniques in order to identify and preserve the neurovascular bundles.

The chronology of second molar development in Brazilians and its application to forensic age estimation

  • Almeida, Manuella Santos Carneiro;Pontual, Andrea Dos Anjos;Beltrao, Rejane Targino;Beltrao, Ricardo Villar;Pontual, Maria Luiza Dos Anjos
    • Imaging Science in Dentistry
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    • 제43권1호
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    • pp.1-6
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    • 2013
  • Purpose: This study investigated the possible correlation between the mineralization of the second molars and the chronological age of a sample population of the state of Paraiba, Brazil. Materials and Methods: One thousand eight hundred fifty-four digitized panoramic images using a scanner of a private dental radiology service were obtained in six months. Of these, 457 were selected from patients aged 4.6 to 16 years who met certain criteria. The images were assessed twice by a radiologist with 5 years experience. A minimum interval of 30 days between the evaluations of the same patient was established. To analyze the relationship between chronological age, calcification level proposed by Demirjian et al in 1973, gender, and tooth, a multiple linear regression model was adjusted, taking age as the response variable (p<0.05). Results: The gender and calcification level were significantly correlated with the age of the patients (p<0.05). There was a significant difference between the average age of the patients' upper teeth compared to the lower ones in both genders (p<0.05). The dental development occurred earlier in female individuals than in male ones, and there was no significant difference between the right and left second permanent molars. Conclusion: It was observed that ethnic variables are related to certain parameters of age and sex identification in the Brazilian population, providing important information for forensic evaluations.