• Title/Summary/Keyword: Dos

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Acute Response to Co-60 Total Body Irradiation (TBI) With 600 cGy at 3 Different Does Rates in the Mice (코발트-60 원격치료기를 이용한 전신 방사선 조사에서 선량율의 차이에 따른 급성효과)

  • Kang Cheol Hoon;Kum Sung Kyu;Shin Sei One;Kim Myung Se
    • Radiation Oncology Journal
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    • v.8 no.2
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    • pp.151-154
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    • 1990
  • The acute effects of variable dos rates to total body irradiation (TBI) were investigaed with 600 cGy of single exposure in the mice as a preclinical model. Total 80 mice (ICR) were used. Twenty of which sewed as controls, receiving no irradiation. All irradiated mice showed a universal decline in their weight and white blood cell count. The degree of weight loss and leukopenia were similar at 3 different dos rate but slightly prominent with 15 cGy/minute group. The degree of recovery among the groups showed no dose rate dependence. Our results suggest that TBI with 15 cGy/mimute may be applicable for clinical therapy with careful evaluation of patient's condition.

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Assessing Distribution of Degree of Saturation for Track Transition Zone Using Soil Water Characteristic Curve (접속부 궤도 성토재료의 함수특성곡선을 이용한 포화도 분포 산정)

  • Choi, Chanyong;Lee, Jungmin;Kwon, Hyeok Min;Oh, Jeongho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.35 no.2
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    • pp.515-524
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    • 2015
  • The number of occurrence of differential settlement and track irregularity at track transition zone recently comes to increase, which leads to frequent maintenance activities that have an impact on train operation. Such track transition zone damages are attributed to the change of mechanical properties of fill materials due to environmental factors such as rainfall and freeze, and thaw. Consequently, this study attempts to establish the soil water characteristic curve (SWCC) of fill materials, and conduct seepage analysis to assess the distribution of degree of saturation (DOS) for track transition zone in case of rainfall. The SWCC of fill materials was successfully obtained using filter paper test method. The results of seepage analysis revealed that rainfall intensity, the slope of backfill, backfill condition (fill or cut), and SWCC are significantly influential in controlling the distribution of DOS.

Piglets' Surface Temperature Change at Different Weights at Birth

  • Caldara, Fabiana Ribeiro;dos Santos, Luan Sousa;Machado, Sivanilza Teixeira;Moi, Marta;de Alencar Naas, Irenilza;Foppa, Luciana;Garcia, Rodrigo Garofallo;de Kassia Silva dos Santos, Rita
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.431-438
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    • 2014
  • The study was carried out in order to verify the effects of piglets' weight at birth on their surface temperature change (ST) after birth, and its relationship with ingestion time of colostrum. Piglets from four different sows were weighed at birth and divided into a totally randomized design with three treatments according to birth weight (PBW): T1 - less than 1.00 kg, T2 - 1.00 to 1.39 kg, and T3 - higher than or equal to 1.40 kg. The time spent for the first colostrum ingestion was recorded (TFS). Images of piglets' surface by thermal imaging camera were recorded at birth (STB) and 15, 30, 45, 60, and 120 min after birth. The air temperature and relative humidity were recorded every 30 min and the indexes of temperature and humidity (THI) were calculated. A ST drop after 15 min from birth was observed, increasing again after sixty minutes. Positive correlations were found between the PBW and the ST at 30 and 45 min after birth. The PBW was negatively correlated with the TFS. The THI showed high negative correlations (-0.824 and -0.815) with STB and after 15 min from birth. The piglet's surface temperature at birth was positively correlated with temperature thereof to 15 min, influencing therefore the temperatures in the interval of 45 to 120 min. The birth weight contributes significantly to postnatal hypothermia and consequently to the time it takes for piglets ingest colostrum, requiring special attention to those of low birth weight.

Continuous PTFE Coating Process on Basalt Sewing Thread (현무암 재봉사의 연속식 테프론 코팅 공정)

  • Lee, Soo
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.2
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    • pp.183-189
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    • 2014
  • On the basis of our previous research results concerning a batch Teflon coating process on the surface of basalt fiber which has superior fire-resistance and chemical resistance, we have tried to set up suitable operating conditions for continuous polytetrafluoroethylene(PTFE) coating process. The basalt fiber was continuously pre-treated with 7.5 wt%(6.5% of DPU) of triethoxytrifluoropropylsilane(TMTFPS) and then coated with 20 wt% of PTFE dispersions containing 0.25 wt% of penetrating agent sodium bis(2-ethylhexyl)sulfo succinate (DOS-Na) to get the highest tensile and loop strengths. After dipping process, the PTFE coated basalt fiber was dried under 2 m drying chamber at $120^{\circ}C$ with 12 m/min of winding speed and consequently sintered under 2 m sintering chamber at $380^{\circ}C$ for 40 s. Conclusively, PTFE coated basalt fiber whose tensile and loop strengths were to $3.4g_f/D$ and $2.3g_f/D$, respectively, applicable to high temperature sewing thread could be continuously prepared with our pilot scale process under optimum conditions.

Nutritional and performance viability of cactus Opuntia-based diets with different concentrate levels for Girolando lactating dairy cows

  • Inacio, Jonas Gomes;da Conceicao, Maria Gabriela;dos Santos, Djalma Cordeiro;de Oliveira, Julio Cesar Vieira;Chagas, Juana Catarina Cariri;de Oliveira Moraes, Glaucia Sabrine;dos Santos Silva, Evannielly Thuanny;de Andrade Ferreira, Marcelo
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.1
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    • pp.35-43
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    • 2020
  • Objective: The aim of this research was to evaluate the effect of different concentrate levels in diets based on cactus Opuntia Stricta (Haw.) Haw cladodes on the performance of lactating Girolando cows. Methods: The experiment involved 10 Girolando multiparous dairy cows at 512.6 kg of body weight (BW) and producing 13.2 kg milk/d, allocated into two 5×5 Latin squares. The experimental treatments consisted of control diet composed by cactus Nopalea cochenillifera. Salm-Dyck. cladodes (Nopalea), forage sorghum silage and concentrate at 20% on dry matter (DM) basis, and four concentrate levels diets (20%, 24%, 28%, and 32%) plus cactus Opuntia stricta (Haw.) Haw. cladodes (Opuntia) and forage sorghum silage. Results: Regarding cows fed control diet, the nutrients intake were greater than for cows fed with cactus Opuntia and concentrate. Regarding concentrate levels, intakes of DM, organic matter (OM), crude protein (CP), non-fiber carbohydrates (NFC), and total digestible nutrients of cows increased linearly. Organic matter, CP, and NDF digestibilities were similar in between to control diet and cactus Opuntia-based diets. The digestibility of NFC increased linearly when the concentrate was inserted. The N balance was the same for control diet and cactus Opuntia-based diets, irrespective the concentrate levels. Conclusion: For cows producing 14 kg/d with 3.5% of fat, it is recommended 32% of concentrate to be included in cactus Opuntia-based diets, and the increase in concentrate level promotes a linear increase in milk yield.

A New Salt-Tolerant Thermostable Cellulase from a Marine Bacillus sp. Strain

  • dos Santos, Yago Queiroz;de Veras, Bruno Oliveira;de Franca, Anderson Felipe Jacome;Gorlach-Lira, Krystyna;Velasques, Jannaina;Migliolo, Ludovico;dos Santos, Elizeu Antunes
    • Journal of Microbiology and Biotechnology
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    • v.28 no.7
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    • pp.1078-1085
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    • 2018
  • A salt-tolerant cellulase secreted by a marine Bacillus sp. SR22 strain with wide resistance to temperature and pH was purified and characterized. Its approximate mass was 37 kDa. The endoglucanase, named as Bc22Cel, was purified by ammonium sulfate precipitation, gel filtration chromatography, and extraction from the gel after non-reducing sodium dodecyl sufate-polyacrylamide gel electrophoresis. The optimal pH value and temperature of Bc22Cel were 6.5 and $60^{\circ}C$, respectively. The purified Bc22Cel showed a considerable halophilic property, being able to maintain more than 70% of residual activity even when pre-incubated with 1.5 M NaCl for 1 h. Kinetic analysis of the purified enzyme showed the $K_m$ and $V_{max}$ to be 0.704 mg/ml and $29.85{\mu}mol{\cdot}ml^{-1}{\cdot}min^{-1}$, respectively. Taken together, the present data indicate Bc22Cel as a potential and useful candidate for industrial applications, such as the bioconversion of sugarcane bagasse to its derivatives.

RNA Polymerase II Inhibitor, ${\alpha}$-Amanitin, Affects Gene Expression for Gap Junctions and Metabolic Capabilities of Cumulus Cells, but Not Oocyte, during In Vitro Mouse Oocyte Maturation

  • Park, Min-Woo;Lee, Hyun-Seo;Kim, Eun-Young;Lee, Kyung-Ah
    • Development and Reproduction
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    • v.17 no.1
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    • pp.63-72
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    • 2013
  • A specific inhibitor of RNA polymerase II, ${\alpha}$-amanitin is broadly used to block transcriptional activities in cells. Previous studies showed that ${\alpha}$-amanitin affects in vitro maturation of cumulus-oocyte-complex (COC). In this study, we evaluated the target of ${\alpha}$-amanitin, and whether it affects oocytes or cumulus cells (CCs), or both. We treated ${\alpha}$-amanitin with different time period during in vitro culture of denuded oocytes (DOs) or COCs in comparison, and observed the changes in morphology and maturation status. Although DOs did not show any change in morphology and maturation rates with ${\alpha}$-amanitin treatment, oocytes from COCs were arrested at metaphase I (MI) stage and CCs were more scattered than control groups. To discover causes of meiotic arrest and scattering of CCs, we focused on changes of cumulus expansion, gap junctions, and cellular metabolism which to be the important factors for the successful in vitro maturation of COCs. Expression of genes for cumulus expansion markers (Ptx3, Has2, and Tnfaip6) and gap junctional proteins (Gja1, Gja4, and Gjc1) decreased in ${\alpha}$-amanitin-treated CCs. However, these changes were not observed in oocytes. In addition, expression of genes related to metabolism (Prps1, Rpe, Rpia, Taldo1, and Tkt) decreased in ${\alpha}$-amanitin-treated CCs but not in oocytes. Therefore, we concluded that the transcriptional activities of CCs for supporting suitable transcripts, especially for its metabolic activities and formation of gap junctions among CCs as well as with oocytes, are important for oocytes maturation in COCs.

Design and Implementation of Interface between the Database and the Application Program (데이터베이스와 응용프로그램 사이의 인터페이스 설계 및 구현)

  • Jung, In-Sook;Lee, Chang-Sup;Cho, Chung-Ho
    • Journal of the Society of Naval Architects of Korea
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    • v.34 no.4
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    • pp.139-147
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    • 1997
  • Most of the existing applications developed undter the DOS environment exchange information with the exterior world through reading and writing files in ASCII format. A package program consisting of numerous modules has to exchange data not only between module program and the input/output files but also between module themselves, and hence information exchange via ASCII file is increasingly inefficient and less accurate as the number of modules increases. The present paper describes the design and the implementation of the interface between the module program and the database which stores all the information necessary for the execution of the application. The interface program is then applied to the existing Propeller Design and Analysis System to show that the interface functions smoothly. The development is performed on the personal computer operating under Windows 95 rather than the workstation under Unix operating system to prove that the design and analysis work can be carried out without limit in time and space.

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Assessment of the anterior loop of the mandibular canal: A study using cone-beam computed tomography

  • Nascimento, Eduarda Helena Leandro do;Pontual, Maria Luiza dos Anjos;Pontual, Andrea dos Anjos;Perez, Danyel Elias da Cruz;Figueiroa, Jose Natal;Frazao, Marco Antonio Gomes;Ramos-Perez, Flavia Maria de Moraes
    • Imaging Science in Dentistry
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    • v.46 no.2
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    • pp.69-75
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    • 2016
  • Purpose: Sufficient area in the interforaminal region is required for dental implant placement, and the anterior loop of the mandibular canal is located within the limits of this area. The aim of this study was to evaluate the prevalence and extent of the anterior loop in a Brazilian sample population using cone-beam computed tomography (CBCT). Materials and Methods: CBCT images from 250 patients (500 hemimandibles) obtained for various clinical indications were randomly selected and evaluated to determine the presence and length of the anterior loop. The length of the anterior loop was then compared based on gender, age, and the side of the mandible. The data were analyzed using the Pearson chi-square test and linear regression analysis. Results: An anterior loop was identified in 41.6% of the cases, and its length ranged from 0.25 mm to 4.00 mm (mean, $1.1{\pm}0.8mm$). The loop had a greater mean length and was significantly more prevalent in males (p=0.014). No significant differences were found between the right and left sides regarding length (p=0.696) or prevalence (p=0.650). Conclusion: In this study, a high prevalence of the anterior loop of the mandibular canal was found, and although its length varied greatly, in most cases it was less than 1 mm long. Although this is a prevalent anatomical variation, safety limits for the placement of implants in this region cannot be established before an accurate evaluation using imaging techniques in order to identify and preserve the neurovascular bundles.

The chronology of second molar development in Brazilians and its application to forensic age estimation

  • Almeida, Manuella Santos Carneiro;Pontual, Andrea Dos Anjos;Beltrao, Rejane Targino;Beltrao, Ricardo Villar;Pontual, Maria Luiza Dos Anjos
    • Imaging Science in Dentistry
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    • v.43 no.1
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    • pp.1-6
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    • 2013
  • Purpose: This study investigated the possible correlation between the mineralization of the second molars and the chronological age of a sample population of the state of Paraiba, Brazil. Materials and Methods: One thousand eight hundred fifty-four digitized panoramic images using a scanner of a private dental radiology service were obtained in six months. Of these, 457 were selected from patients aged 4.6 to 16 years who met certain criteria. The images were assessed twice by a radiologist with 5 years experience. A minimum interval of 30 days between the evaluations of the same patient was established. To analyze the relationship between chronological age, calcification level proposed by Demirjian et al in 1973, gender, and tooth, a multiple linear regression model was adjusted, taking age as the response variable (p<0.05). Results: The gender and calcification level were significantly correlated with the age of the patients (p<0.05). There was a significant difference between the average age of the patients' upper teeth compared to the lower ones in both genders (p<0.05). The dental development occurred earlier in female individuals than in male ones, and there was no significant difference between the right and left second permanent molars. Conclusion: It was observed that ethnic variables are related to certain parameters of age and sex identification in the Brazilian population, providing important information for forensic evaluations.