• Title/Summary/Keyword: Dongjae

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Missing values imputation for time course gene expression data using the pattern consistency index adaptive nearest neighbors (시간경로 유전자 발현자료에서 패턴일치지수와 적응 최근접 이웃을 활용한 결측값 대치법)

  • Shin, Heyseo;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.33 no.3
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    • pp.269-280
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    • 2020
  • Time course gene expression data is a large amount of data observed over time in microarray experiments. This data can also simultaneously identify the level of gene expression. However, the experiment process is complex, resulting in frequent missing values due to various causes. In this paper, we propose a pattern consistency index adaptive nearest neighbors as a method of missing value imputation. This method combines the adaptive nearest neighbors (ANN) method that reflects local characteristics and the pattern consistency index that considers consistent degree for gene expression between observations over time points. We conducted a Monte Carlo simulation study to evaluate the usefulness of proposed the pattern consistency index adaptive nearest neighbors (PANN) method for two yeast time course data.

Design of MUSIC-based DoA Estimator for Bluetooth Applications (Bluetooth 응용을 위한 MUSIC 알고리즘 기반 DoA 추정기의 설계)

  • Kim, Jongmin;Oh, Dongjae;Park, Sanghoon;Lee, Seunghyeok;Jung, Yunho
    • Journal of IKEEE
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    • v.24 no.1
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    • pp.339-346
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    • 2020
  • In this paper, we propose an angle estimator that is designed to be applied to Bluetooth low-power application technology based on multiple signal classification (MUSIC) algorithm, and present the result of implementation in FPGA. The MUSIC algorithm is designed for H/W high-speed design because it requires a lot of calculations due to high accuracy, and the snapshot variable is designed to cope with various resolution requirements of indoor systems. As a result of the implementation with Xilinx zynq-7000, it was confirmed that 9,081 LUTs were implemented, and it was designed to operate at =the operating frequency of 100MHz.

Evaluation of the Performance of Transit Assignment Algorithms for Urban Rail Networks (도시철도 교통량 배정 알고리즘의 적합성 평가)

  • Jung, Dongjae;Chang, Justin S.
    • Journal of the Korean Society for Railway
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    • v.17 no.6
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    • pp.433-442
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    • 2014
  • This paper evaluates the performance of transit assignment algorithms for urban rail networks. The accuracy of the algorithms is essential not just for travel forecasting but also for the area of applications such as the assessment of road vulnerability and the fare adjustments between train operating companies. Nonetheless, the suitability and caveats for the series of computational steps have not yet been much discussed. This study thus considers the characteristics that are appropriate for investigating Seoul rail travelers using three representative transit assignment algorithms: the optimal strategy algorithm, route choice algorithms, and the Dial's algorithm. Both the theoretical foundation and the empirical performance are examined. The results demonstrate that the Dial's algorithm is superior in terms of the theoretical soundness and the computational efficiency.

Forced Vibration and Structural Response Prediction for Impeller in Resonant Conditions due to Diffuser Vanes (디퓨저 베인에 기인한 공진조건에서의 임펠러 강제진동 및 구조응답 예측)

  • Kim, Yongse;Kong, Dongjae;Shin, SangJoon;Park, Kihoon;Im, Kangsoo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.22 no.4
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    • pp.24-35
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    • 2018
  • Impeller blades in the centrifugal compressor are subjected to periodic aerodynamic excitations by interactions between the impeller and the diffuser vanes (DV) in resonant conditions. This may cause high cycle fatigue (HCF) and eventually result in failure of the blades. In order to predict the structural response accurately, the aerodynamic excitation and the major resonant conditions were predicted using unsteady computational fluid dynamics (CFD) and structural analysis. Then, a forced vibration analysis was performed by going through one-way fluid-structure interaction (FSI). A numerical analysis procedure was established to evaluate the structural safety with respect to HCF. The numerical analysis procedure proposed in this paper is expected to contribute toward preventing HCF problems in the initial design stage of an impeller.

Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea

  • Yu, Jihye;Kim, Woojin;Chang, Yoon Kyung;Kim, Tong-Soo;Hong, Sung-Jong;Ahn, Hye-Jin;Nam, Ho-Woo;Kim, Dongjae
    • Parasites, Hosts and Diseases
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    • v.59 no.3
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    • pp.251-256
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    • 2021
  • We find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in Gyodong-myeon and Samsan-myeon of Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea. Seroepidemiological data of toxoplasmosis surveyed using rapid diagnostic tests for the residents in the areas in 2019 were analyzed to detect clusters of the infection. The cluster was investigated using the SaTScan program which is based on Kulldorff's scan statistic. The clusters were found with P-values in each region analyzed in the program, and the risk and patient incidence of specific areas can be examined by the values such as relative risk and log likelihood ratio. Jiseok-ri and Insa-ri were found to be a cluster in Gyodong-myeon and Seokmo-ri was the cluster in Samsan-myeon. Yangji-ri and Igil-ri were found to be a cluster in Cheorwon-gun and Madal-ri and Baebong-ri were the cluster in Goseong-gun. This findings can be used to monitor and prevent toxoplasmosis infections occurring in vulnerable areas.

Design and Implementation of Multi-Cloud Service Common Platform (멀티 클라우드 서비스 공통 플랫폼 설계 및 구현)

  • Kim, Sooyoung;Kim, Byoungseob;Son, Seokho;Seo, Jihoon;Kim, Yunkon;Kang, Dongjae
    • Journal of Korea Multimedia Society
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    • v.24 no.1
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    • pp.75-94
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    • 2021
  • The 4th industrial revolution needs a fusion of artificial intelligence, robotics, the Internet of Things (IoT), edge computing, and other technologies. For the fusion of technologies, cloud computing technology can provide flexible and high-performance computing resources so that cloud computing can be the foundation technology of new emerging services. The emerging services become a global-scale, and require much higher performance, availability, and reliability. Public cloud providers already provide global-scale services. However, their services, costs, performance, and policies are different. Enterprises/ developers to come out with a new inter-operable service are experiencing vendor lock-in problems. Therefore, multi-cloud technology that federatively resolves the limitations of single cloud providers is required. We propose a software platform, denoted as Cloud-Barista. Cloud-Barista is a multi-cloud service common platform for federating multiple clouds. It makes multiple cloud services as a single service. We explain the functional architecture of the proposed platform that consists of several frameworks, and then discuss the main design and implementation issues of each framework. To verify the feasibility of our proposal, we show a demonstration which is to create 18 virtual machines on several cloud providers, combine them as a single resource, and manage it.

Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea

  • Jung, Jeehi;Lee, Jinyoung;Chang, Yoon Kyung;Ahn, Seong Kyu;Park, Seo Hye;Hong, Sung-Jong;Lee, Jihoo;Chong, Chom-Kyu;Ahn, Hye-Jin;Nam, Ho-Woo;Kim, Tong-Soo;Kim, Dongjae
    • Parasites, Hosts and Diseases
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    • v.59 no.1
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    • pp.9-14
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    • 2021
  • Toxoplasma gondii seroprevalence have been rapidly increasing in some parts of Korea. We analyzed prevalence of anti-Toxoplasma gondii antibodies, using a rapid diagnostic test (RDT), in the sera of 552 residents in Ganghwagun, 661 ones in Cheorwon-gun, and 305 ones in Goseong-gun, Korea in 2019. IgG/IgM RDT mounted with recombinant fragment of major surface antigen (SAG1), glutathione-S-transferase-linker-SAG1A, were applied to the sera. IgG seroprevalence was 28.1% in Ganghwa-gun, 19.5% in Cheorwon-gun and 35.7% in Goseong-gun. Odds ratios comparing Cheorwon vs Ganghwa was 0.63 (P=0.001) and Goesong versus Ganghwa was 1.47 (P=0.01) adjusting age and sex. Goseong had highest seroprevalence among the 3 counties both in crude rates and logistic regression. Although Cheorwon and Goseong are adjacent to the demilitarized zone (DMZ) in Korea, seroprevalence rate was much higher in Goseong. Further investigation on other DMZ-closed areas is necessary whether they have high prevalence rates compared to the other areas. T. gondii prevalence in Korea is still persists; proper health policy should be established.

Accuracy of genotype imputation based on reference population size and marker density in Hanwoo cattle

  • Lee, DooHo;Kim, Yeongkuk;Chung, Yoonji;Lee, Dongjae;Seo, Dongwon;Choi, Tae Jeong;Lim, Dajeong;Yoon, Duhak;Lee, Seung Hwan
    • Journal of Animal Science and Technology
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    • v.63 no.6
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    • pp.1232-1246
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    • 2021
  • Recently, the cattle genome sequence has been completed, followed by developing a commercial single nucleotide polymorphism (SNP) chip panel in the animal genome industry. In order to increase statistical power for detecting quantitative trait locus (QTL), a number of animals should be genotyped. However, a high-density chip for many animals would be increasing the genotyping cost. Therefore, statistical inference of genotype imputation (low-density chip to high-density) will be useful in the animal industry. The purpose of this study is to investigate the effect of the reference population size and marker density on the imputation accuracy and to suggest the appropriate number of reference population sets for the imputation in Hanwoo cattle. A total of 3,821 Hanwoo cattle were divided into reference and validation populations. The reference sets consisted of 50k (38,916) marker data and different population sizes (500, 1,000, 1,500, 2,000, and 3,600). The validation sets consisted of four validation sets (Total 889) and the different marker density (5k [5,000], 10k [10,000], and 15k [15,000]). The accuracy of imputation was calculated by direct comparison of the true genotype and the imputed genotype. In conclusion, when the lowest marker density (5k) was used in the validation set, according to the reference population size, the imputation accuracy was 0.793 to 0.929. On the other hand, when the highest marker density (15k), according to the reference population size, the imputation accuracy was 0.904 to 0.967. Moreover, the reference population size should be more than 1,000 to obtain at least 88% imputation accuracy in Hanwoo cattle.

Relationship between Clonorchis sinensis Infection and Cholangiocarcinoma in Korea

  • Kim, Hwa Sun;Nam, Ho-Woo;Ahn, Hye-Jin;Kim, Dongjae;Kim, Yeong Hoon
    • Parasites, Hosts and Diseases
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    • v.60 no.4
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    • pp.261-271
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    • 2022
  • This study provides an overview of the current status of clonorchiasis and cholangiocarcinoma (CCA), and their relationship in Korea during 2012-2020. Data were obtained from the Health Insurance Review & Assessment Service of Korea. Cluster, trend, and correlation analyses were performed. Gyeongsangnam-do and Seoul had the highest average number of cases (1,026 and 4,208) and adjusted rate (306 and 424) for clonorchiasis and CCA, respectively. The most likely clusters (MLC) for clonorchiasis and CCA were Busan/Gyeongsangnam-do/Ulsan/Daegu/Gyeongsangbuk-do (Relative Risk; RR=4.55, Likelihood Ratio; LLR=9,131.115) joint cluster and Seoul (RR=2.29, LLR=7,602.472), respectively. The MLC for clonorchiasis was in the southeastern part of Korea, while that for CCA was in the southern part. Clonorchiasis showed a decreasing trend in the southeastern districts, while increased in the southwestern districts. Cities in the central region had a decreasing trend, while the western districts had an increasing trend. In most adults (30-59), infection rate of clonorchiasis showed a significant decrease until 2018, while thereafter increased, although not significant. CCA showed a sharply decreasing tendency. The incidence of clonorchiasis and CCA were positively correlated. In general, the correlation was weak (r=0.39, P<0.001), but it was strongly positive around the 4 river basins (r=0.74, P<0.001). This study might provide an analytic basis for developing an effective system against clonorchiasis and CCA.

Spatial Configuration of Education Area in Do-dong Seowon (도동서원의 강학영역의 공간구성)

  • Tae-Joong Kang
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.1
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    • pp.59-68
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    • 2023
  • A new type of private education institute appeared starting from the 16th century, called Seowon consist of educational spaces and Jesa(a form of memorial ritual for the family's ancestors) space. Seowon Architecture is representative Confucian Architecture. Seowon is a kind of private school and it is a higher educational institute. the time of establishment was from the middle of 16th century to the end of 19th century, but the famous Seowon which remains up to now had been mainly built from the end of 16th century to the beginning of 17th century. Seowon was built on a quiet place far from the town for Students and Scholars to concentrate on their study. and it has beautiful surrounding scenery. Seowon has a place for study in the front and a place for sacrifice at the back regardless of configuration of ground. Gangdang is a building in the place for study in which teacher and students study. It is smilar place to Myongryundang of Hyanggyo. As a plan composition, there is a wide Daechong and two rooms at the both sides. Infront of Cangdang, there are Dongjae and Seojae on the right and the left side which are student' dormitory. This study argues that the Confucianist ideas and topography are the factors that determine the hierarchy Seowon. In light of this, A Study on Spatial Configuration of Education Area in Do-dong Sewon attempted to conduct an analysis by applying such backgrounds, and therefore studied the arrangement rules and construction methods for Seowons.