Parasites, Hosts and Diseases

  • 제59권1호
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  • Pages.9-14
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  • 2021
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea

  • Jung, Jeehi (Department of Biomedicine Health Science, College of Medicine, The Catholic University of Korea) ;
  • Lee, Jinyoung (Department of Tropical Medicine, Inha University School of Medicine) ;
  • Chang, Yoon Kyung (Department of Parasitology, College of Medicine, The Catholic University of Korea) ;
  • Ahn, Seong Kyu (Department of Tropical Medicine, Inha University School of Medicine) ;
  • Park, Seo Hye (Department of Tropical Medicine, Inha University School of Medicine) ;
  • Hong, Sung-Jong (Department of Medical Environmental Biology, Chung-Ang University College of Medicine) ;
  • Lee, Jihoo (Genbody Inc.) ;
  • Chong, Chom-Kyu (Genbody Inc.) ;
  • Ahn, Hye-Jin (Department of Parasitology, College of Medicine, The Catholic University of Korea) ;
  • Nam, Ho-Woo (Department of Parasitology, College of Medicine, The Catholic University of Korea) ;
  • Kim, Tong-Soo (Department of Tropical Medicine, Inha University School of Medicine) ;
  • Kim, Dongjae (Department of Biomedicine Health Science, College of Medicine, The Catholic University of Korea)
  • 투고 : 2020.10.05
  • 심사 : 2021.01.15
  • 발행 : 2021.02.28
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초록

Toxoplasma gondii seroprevalence have been rapidly increasing in some parts of Korea. We analyzed prevalence of anti-Toxoplasma gondii antibodies, using a rapid diagnostic test (RDT), in the sera of 552 residents in Ganghwagun, 661 ones in Cheorwon-gun, and 305 ones in Goseong-gun, Korea in 2019. IgG/IgM RDT mounted with recombinant fragment of major surface antigen (SAG1), glutathione-S-transferase-linker-SAG1A, were applied to the sera. IgG seroprevalence was 28.1% in Ganghwa-gun, 19.5% in Cheorwon-gun and 35.7% in Goseong-gun. Odds ratios comparing Cheorwon vs Ganghwa was 0.63 (P=0.001) and Goesong versus Ganghwa was 1.47 (P=0.01) adjusting age and sex. Goseong had highest seroprevalence among the 3 counties both in crude rates and logistic regression. Although Cheorwon and Goseong are adjacent to the demilitarized zone (DMZ) in Korea, seroprevalence rate was much higher in Goseong. Further investigation on other DMZ-closed areas is necessary whether they have high prevalence rates compared to the other areas. T. gondii prevalence in Korea is still persists; proper health policy should be established.

키워드

참고문헌

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