• 한국실내디자인학회논문집
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• 제23권5호
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• pp.139-145
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• 2014

As life is changing, modern people are interested in culture life more than the past and as a result Art Exhibition increases. Nowadays many methods of exhibit are introduced, especially Direct experience. Trick Art Experience exhibition introduced Direct experirence to a work of art for interests and used props, objets, images, and sounds for maximizing experience element. Trick Art Experience exhibition added humor as imitating famous painting and gave a deep impression through the optical illusion technique which make flat structure look three-dimensional structure. Recently, demands for Experience exhibition which are like Trick Art increase. This study figure out pros and cons through a comparison analysis of direction and component about Trick Art Experience exhibition and find a check list about making an audience active about experience. From now on, we have an object about showing design data including customer satisfaction measurement to make various expressions of direction and component about Experience Art through a case analysis. We have firsthand visited case spaces to experience the spaces and prepared a check list for the relevant types of expressions. Referring to the exhibit work classification system, components that correspond to Trick Art Experience exhibition were grouped according to constituting items. Among the types of expressions, the levels of satisfaction with Experience exhibition and Participating exhibit were found to be high and the level of satisfaction with Heart Moving exhibit was found to be low through surveys. Among the components, the levels of satisfaction with stereograms and formative effect elements were found to be high and those of spatial changes and media effects were found to be low through surveys. Therefore, the expressions should be reinforced and the components should be improved.

• 한국식품과학회지
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• 제22권2호
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• pp.192-198
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• 1990

콩(단엽콩, 광교, $ES_2)을 조리 $(100-135^{\circ}C)$하는 과정에서 일어나는 텍스쳐, 고형물 및 단백질의 변화를 분석하였다. 콩의 텍스쳐는 Instron을 이용하는 Puncture test로써 측정하였으며 조직의 변화과정을 주사전자현미경 (SEM)을 이용하여 미세구조를 관찰한 결과 수화가 되면서 세포벽이 허물어지고 protein body가 드러남을 관찰할 수 있었고 일정온도에서 조리 시간이 길어짐에 따라 세포벽이 서로 분리되고 그 구조가 흐트러짐을 알 수 있었다. 침출액 중의 고형물은 조리시간이 길어질수록 많이 용출되었으며 $100^{\circ}C$. 80분에서 11.5-13.2% 정도가 되었다. 용출된 총 고형물 중 11-21%는 단백질이었으며 단백질 용출 비율은 조리시간에 따라 증가하였다.

• 한국수학사학회지
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• 제24권4호
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• pp.97-118
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• 2011

수학사적으로 함수개념은 비례관계, 종속변수, 식, 대응 등으로 발달되어왔으며 수학교육과정에서는 3차, 7차, 7차 개정안에서 중학교 1학년에서 함수개념 도입을 위한 함수의 정의에서 강조점 바뀌었고 이러한 수정의 핵심은 "종속"과 "대응"이다. 본 연구는 종속과 대응에 초점을 둔 수업의 장단점을 비교하고자 각각을 대표할 수 있는 모델로서 물통 모델과 자판기 모델을 선정하여 중학교 1학년을 대상으로 함수의 개념과 함수의 표현에 대한 2차시 수업을 실시하고 형성평가 문항분석을 통하여 두 모델의 차이점과 효율성을 파악하였으며, 3개월 후 파지 효과를 조사하였다. 자판기모델은 중학교 1학년 학생의 함수의 정의 이해 뿐 아니라 특히 개념이미지를 만들고 회상하는데 도움을 주었다. 물통모델은 정의역의 모든 원소가 종속변수에 대응 된다는 "임의성"을 이해하는 데는 상대적으로 어려움을 나타냈지만, 함수식의 표현과 관련해서는 좋은 역할을 한 것으로 판단되었다.

• 대한한의학방제학회지
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• 제15권2호
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• pp.99-111
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• 2007

In the present study, the anti-inflammatory effect of "Jungcheonhwadamgangki-tang ga Antler" water extract was tested in Xylene-Application mouse ear acute inflammation model. The test articles were once dosed before Xylene-Application, and the changes on body weight and ear weights and histopathological observation of induced ear were conducted with ear histomorphometry. The obtained results were as follows. The increases of absolute and relative ear weight detected in vehicle control compared to that of sham, were significantly and dose-dependently inhibited by Jungcheonhwadamgangki-tang ga Antler in the present study. A classic acute inflammatory histological changes such as subcutaneous edema, thickness and infiltration of inflammatory cells, was detected in vehicle control. However, these histological changes were significantly and dose-dependently inhibited by Jungcheonhwadamgangki-tang ga Antler. In addition, the increases of ear thickness half and thickness full detected in the vehicle control were also dose-dependently decreased in the all Jungcheonhwadamgangki-tang ga Antler-dosing groups. Base on these results, it is concluded that Jungcheonhwadamgangki-tang ga Antler extracts has clear anti-inflammatory effect on the acute inflammation such as bronchial asthma.

• 무역상무연구
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• 제69권
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• pp.407-426
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• 2016

The Marine Insurance Act 1906 (MIA 1906) has been a successful piece of legislation, having rarely been amended and having established, or served as an influence in the development of, the basis of marine insurance legislation in several countries. However, it has been recognised that some parts of the MIA 1906 have begun to show their antiquated nature, especially where established principles which were once thought to reflect undoubted propositions of law are now being openly criticised. Since 2006, the Law Commission and Scottish Law Commission (the 'Law Commissions') have been engaged in a major review of insurance contract law, finally leading to the Insurance Act 2015. The Insurance Act 2015 received Royal Assent on 12 February 2015, and was based primarily on the joint recommendations of the Law Commissions. The 2015 Act made substantial changes to several main areas of marine insurance law & practice: (i) the replacement of the pre-contractual duty of disclosure with a duty to make a "fair presentation of the risk"; (ii) the abolition of the "insurance warranty" under the Marine Insurance Act 1906, s.33, and provision of a new default remedy of suspension of liability until the breach is cured; (iii) partial codification of the fraudulent claims rule in insurance contract law, etc. The Act did not provide for any new statutory duty for insurers to investigate or pay claims in a timely fashion, although this may be revisited in the next Parliament. Moreover, the Law Commissions have reopened their consideration of the doctrine of insurable interest. The 2015Actmay not then signal the end of the legislative programme in this area.

• 해양환경안전학회지
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• 제18권3호
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• pp.267-272
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• 2012

에너지 생성에 따른 탄소배출문제로 국제 에너지 기구는 세계 주요국의 에너지 효율을 15~30[%]이상 향상시키도록 권고하고 있으며, 국내 에너지 정책 동향도 에너지 절감 및 탄소 배출에 대해 정부에서 인센티브 및 페널티 프로그램을 제고하는 방향으로 가고 있다. 각국의 산업 현장에서 유체 이송용 펌프가 전기에너지의 20[%]를 소비하고 있는 실정으로, 주요 에너지 낭비 요인으로는 장시간 운전에 따른 효율 저하, 부적절한 설계 및 설비 등이 있다. 이러한 낭비를 줄이기 위해 펌프의 효율을 측정하여 펌프의 운전 상태를 진단하고자, 본 논문에서는 열역학적 방법으로 온도와 압력센서만을 활용하여 펌프의 최고 효율점을 측정할 수 있는 방법을 제시하고 실제 펌프의 효율을 계산하여 펌프제조사에서 제공한 성능곡선과 비교한 결과 유사한 성능곡선을 얻어 그 유효성을 확인하였다.

• 대한불안의학회지
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• 제7권2호
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• pp.119-125
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• 2011

Objectives : The three symptom clusters of posttraumatic stress disorder (PTSD) are reexperience, avoidance, and hyperarousal. Alcohol use disorders frequently co-occur with PTSD, and possible functional correlations are suspected. Scholarly evaluation of the differences between the symptoms of PTSD and those of alcohol problems may be useful in understanding the pathophysiology of the comorbidity. Methods : We recruited Vietnam veterans with PTSD (n=97) and without PTSD (n=132). The alcohol use disorder identification test (AUDIT), and clinician-administered PTSD scale (CAPS) were administered to participants. The PTSD group was divided into two categories: those with PTSD only (n=57) and those with concurrent alcohol-related problems (n=40). Results : The PTSD group showed higher AUDIT scores compared to the control group. In the PTSD group, participants with alcohol problems had a severer symptoms of recurrent dream and sleep disturbance symptoms compared to the PTSD only group. No significant differences were found in the three major symptom clusters of PTSD. Conclusion : These findings support the proposed existence of a functional correlation between PTSD and alcohol use disorder. Clinicians should carefully evaluate and treat comorbid alcohol use disorder in patients with PTSD.

• 대한불안의학회지
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• 제13권2호
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• pp.123-131
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• 2017

Objective : The PTSD Checklist (PCL) is a self-report screen for posttraumatic stress disorder (PTSD) that can be scored for both diagnostic assessment and symptom severity measurement. The most recent revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) contains a number of changes to the definition of PTSD, and the aim of this study was to assess the psychometric properties of the Korean version of the PCL for the DSM-5 (PCL-5-K). Methods : The participants were 204 Korean veterans of the Vietnam War who completed the PCL-5-K, the Mini Mental Status Examination (MMSE), PTSD module of Structured Clinical Interview for DSM-5, Research Version (SCID5-RV PTSD module), Korean version of Impact of Event Scale-Revised (IES-R-K) and Combat Exposure Scale (CES-K). Results : The PCL-5-K demonstrated good internal consistency (${\alpha}=0.972$) and test-retest reliability (r=0.96); the suggested cut-off score for PTSD diagnosis was ${\geq}37$ with 0.88 sensitivity and 0.96 specificity. The PCL-5-K scale correlated highly with the IES-R-K and CES-K. Factor analysis identified only one factor. Conclusion : Among elderly Korean veterans of the Vietnam War, the PCL-5-K demonstrated similar psychometric qualities to those of both the original PCL and subsequent versions. It is expected that the PCL-5-K will be a useful PTSD screening tool.

• Journal of Microbiology and Biotechnology
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• 제23권8호
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• pp.1154-1158
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• 2013

Ganciclovir resistance of human cytomegalovirus is associated with mutations in the viral UL97 gene and poses severe problems for immunocompromised patients. In this study, PCR-based restriction fragment length polymorphism and sequencing analyses detected the UL97 D605E mutation in all five clinical isolates from patients with ganciclovir-resistant human cytomegalovirus infection during prolonged ganciclovir therapy, whereas the M460V mutation was only present in 1 of 5 isolates. On the other hand, the detection rates of the D605E mutation in the stored available DNA samples from the donor and allogeneic stem cell transplantation recipients were 66.7% and 93.7%, respectively, suggesting that the presence of D605E mutation was not associated with the ganciclovir exposure. Although the D605E mutation may not be related to ganciclovir resistance, we suggest that this mutation could be an important molecular marker of human cytomegalovirus evolution in East Asian countries. Moreover, the restriction fragment length polymorphism method using the restriction enzyme HaeIII, which is generally used to detect the UL97 A591V mutation, could also detect the D605E mutation and may therefore be a useful tool for future research on the investigation of UL97 gene mutations.

• Applied Biological Chemistry
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• 제41권3호
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• pp.219-223
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• 1998

작물 병해충에 대한 무공해 미생물 농약 개발의 일환으로 곤충 병원성 곰팡이 Metarhizium anisopliae의 분자생물학적 육종을 위해 이 균주의 형질전환계를 확립하였다. M. anisopliae의 원형질체를 제작하여 benomyl 약제에 대하여 저항성을 나타내는 Aspergillus flavus 유래의 ${\beta}-tubulin$ 유전자를 갖는 pBRG-4 plasmid DNA를 polyethylene glycol 방법으로 형질 전환하였다. 이 형질전환은 pBRG-4 DNA $50\;{\mu}g$당 10개의 효율로 이루어졌으며, 그 결과 야생형 균주들의 $2.5\;{\mu}g/ml$ 농도의 benomyl 존재 하에서도 성장이 억제되는데 반하여 선발된 형질전환체들은 $5.0\;{\mu}g/ml$ 농도의 benomyl 함유 배지에서도 잘 성장하였다. 또한 이 형질전환체들의 chromosomal DNA를 분리하여 Southern 분석한 결과 ${\beta}-tubulin$ 유전자가 homologous recombination에 의하여 M. anisopliae의 genome속에 삽입 되었음을 확인하였다.