• Title/Summary/Keyword: Divided differences method

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Relationship Between Age and Pleural Fluid A denosine Deaminase Activity in Patients with Tuberculous Pleural Effusion (결핵성 흉수 환자에서 연령과 흉수 Adenosine Deaminase 활성도와의 관련성)

  • Kim, Chong-Ju;Yeon, Kyu-Min;Kim, Shin-Tae;Wang, Joon-Ho;Yoo, Kwang-Ha
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.6
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    • pp.608-615
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    • 2002
  • Background : ADA is an enzyme found in most cells, and is involved in purine metabolism, but its chief role concerns the proliferation and differentiation of lymphocytes, especially T-lymphocytes. For that reason ADA has been looked on as a marker of cell-mediate immunity, which is the key mechanism of the tuberculous pleural effusion. Thus, the pleural fluid ADA activity is increased in the tuberculous pleural effusion. Age associated immune decline is characterized by decreases in both B and T-lymphocyte function and the former may be largely a result of the latter. Therefore, the pleural fluid ADA activity would be lower in old rather than in young, patients with tuberculous pleural effusion. We studied the relationship between age, and pleural fluid ADA activity, in patients with tuberculous pleural effusion. Materials and Methods : In the 46 patients with tuberculous pleural effusion enroll in this study, the pleural fluid ADA activities were measured by means of an automated kinetic method. Results : The mean age of the patients was $53.0{\pm}22.0$ years, with a male to female ratio of 30:16. The patients were divided into two groups, young patients, regarded as < 65 and old regarded as ${\geq}65$ years with 28 and 18 patients, respectively. The pleural fluid ADA activity in both groups show significant differences : $99.4{\pm}22.6$ IU/L(young patients) Vs. $75.8{\pm}30.9$ IU/L(old patients)(p<0.05), but a negative correlation with age (r=-0.311, p<0.05). Conclusion : Although pleural fluid ADA activity was not adequately increased, tuberculous pleural effusion, in older patients, would have to be considered clinically suspicious tuberculous pleural effusion.

Evaluation of Laying Performances in Laying Hens Molted by Dietary Induction (산란계의 유도 환우에 있어서 급이환우 방법의 평가)

  • Hong, E.C.;Na, J.C.;Chung, I.B.;Choi, Y.H.;Park, H.D.;Chung, W.T.;Lee, H.J.;You, D.C.;Kim, H.K.;HwangBo, J.
    • Korean Journal of Poultry Science
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    • v.35 no.1
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    • pp.15-20
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    • 2008
  • This study aimed at evaluating the effects of a molting diet method in molt induction and post-molt performance of laying hens. Eighty-one ISA Brown hens at 62 wk of age were randomly divided into three groups. After a 4-wk preliminary period, a control group was fed a corn-soybean-based layer diet, and for the other groups, molting was induced by starvation (MS) or feeding a molting diet (MD). For the MS group, feed was withdrawn for 2 wk; this was followed by feeding a layer diet every other day for 1 wk and then the control diet. The MD group was fed a molting diet containing low-protein and low-energy diet based for 4 wk; this was followed by feeding a layer diet. They had a free access to their diet and water. Egg production, egg quality, feed intake, and ovary and oviduct weights were measured throughout the experimental period. During molting, the feed intake in the MD group was lower than that of the control. Body weight of the molted groups was significantly reduced. The MS group feeding totally ceased egg production within 4d; after the initiation of feeding and decreased; in the MD group, egg production to 9.3% by d 10. On d 14, the ovaries and oviducts of the molted groups were distinctly lighter than those of the control. Throughout the post-molt period, egg production and egg shell thickness of the molted group improved; but there were no significant differences. Eggs from the MD-fed or control group were heavier than those of the MS-fed or control group. Finally, feeding of a low-protein and low-energy diet effectively induces molting and increase post-molt production, but further research will be conducted to determine the effects of the molt diet with other ingredients and to reduce the energy level of the molt diet for maximizing molt induction and post-molt egg quality.

A Comparison of Species Composition and Stand Structure of the Forest Vegetation between Inhabited and Uninhabited Island in the South Sea, Korea (유인도서와 무인도서 산림식생의 종조성 및 군락 구조 비교)

  • Kim, Jun-Soo;Jeon, Chul-Hyun;Jung, Sung-Cheol;Kim, Chan-Soo;Won, Hyun-Gyu;Cho, Joon-Hee;Cho, Hyun-Je
    • Korean Journal of Environment and Ecology
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    • v.30 no.4
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    • pp.771-782
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    • 2016
  • For basic information collection for the ecological management of forest vegetation in Korean island areas, forest vegetation between inhabited(Daemodo) and uninhabited(Gudo) island was classified in the Z-M phytosociological method and their ecological characteristics in terms of both floristic composition and structure analyzed. Forest vegetation of Daemodo and Gudo were divided into a total of 11 units and 8 units, respectively. Total cover and species diversity index(H') of forest vegetation showed significant differences between the two island, Daemodo has a high value in the tree layer, but, Gudo has a high value in the shrub layer. Composition of Life forms, Daemodo was N-$R_5-D_2$-e and Gudo MM-$R_5-D_2$-e. Family importance value(FIV), Daemdo has a high value in Theaceae(12.2) and Pinaceae(12.0) and Gudo in Lauraceae(16.5) and Fagaceae (11.6). The percentage of the total number of species in the family level, Daemodo is Asteraceae(4.5%) was the highest and Gudo is Liliaceae(7.3%). Indicator species of forest vegetation of the two islands, Daemodo is Nanophanerophytes(N) including Smilax china, Ligustrum japonicum and Eurya japonica was significant inicator species and Gudo is Megaphanerophytes(MM) including Dendropanax morbiferus, Castanopsis sieboldii and Actinodaphne lancifolia.

Outcomes of the Modified Maze Procedure for Chronic Atrial Fibrillation Combined with Rheumatic Mitral Valve Disease (류마티스성 승모판막질환과 동반된 만성 심방세동 치료에 대한 변형 Maze 술식의 결과)

  • Baek Man-Jong;Kim Jae-Hyun;Seo Hong-Joo;Lee Chang-Ha;Oh Sam-Se;Na Chan-Young
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.681-691
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    • 2006
  • Background: The aim of this study was to investigate the mid-term outcomes of our modifications to the maze procedure using cryoablation for treating atrial fibrillation associated with rheumatic mitral valve disease. Material and Method: Between March 2000 and February 2004, 177 consecutive patients underwent the modified maze procedure with the use of cryoablation concomitant with mitral valve surgery for atrial fibrillation associated with rheumatic mitral valve disease, and were divided into three groups: (1) modified Cox-maze III (CM group, n=88): (2) modified Kosakai-maze (KM group, n=63): and (3) left atrial maze procedure (LA group, n=26). The postoperative and follow-up results were analyzed and compared between the groups. Result: There were three hospital deaths (1.7%) and no significant differences in the incidence of postoperative complications between the three groups. The operative time, such as the cardiopulmonary bypass and aortic crossclamp time, were significantly longer in the CM group than in the KM and LA groups, respectively (p<0.0001). The mean follow-up was $22.4{\pm}15.1$ months ($1\sim52.6$ months) for all patients. One late death developed in the CM group (0.0%). At last follow-up, 139 patients exhibited sinus rhythm (79.9%), which was also regained in 67 patients (77.9%) in the CM group, 50 (80.7%) in the KM group and 22 (84.6%) in the LA group (p=0.743). The actuarial freedom from stroke at 4 years was $84.5{\pm}9.4%$ in the CM group, $95.0{\pm}4.9%$ in the KM group, and $92.9{\pm}6.9%$ in the LA group (p=0.916). Conclusion: The modified maze procedure using cryoablation is safe and effective in treating chronic atrial fibrillation associated with rheumatic mitral valve disease.

Expression of CD40, CD86, and HLA-DR in CD1c+ Myeloid Dendritic Cells Isolated from Peripheral Blood in Primary Adenocarcinoma of Lung (원발성 폐선암환자의 말초혈액에서 분리한 CD1c+ 골수성 수지상 세포에서의 CD40, CD86 및 HLA-DR의 발현)

  • Kang, Moon-Chul;Kang, Chang-Hyun;Kim, Young-Tae;Kim, Joo-Hyun
    • Journal of Chest Surgery
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    • v.43 no.5
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    • pp.499-505
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    • 2010
  • Background: There have been several reports using animal experiments that CD1-restricted T-cells have a key role in tumor immunity. To address this issue, we studied the expression of markers for CD1c+ myeloid dendritic cells (DCs) isolated from peripheral blood in the clinical setting. Material and Method: A total of 24 patients with radiologically suspected or histologically confirmed lung cancer who underwent pulmonary resection were enrolled in this study. The patients were divided according to histology findings into three groups: primary adenocarcinoma of lung (PACL), primary squamous cell carcinoma of lung (PSqCL) and benign lung disease (BLD). We obtained 20 mL of peripheral venous blood from patients using heparin-coated syringes. Using flow-cytometry after labeling with monoclonal antibodies, data acquisition and analysis were done. Result: The ratio of CD1c+CD19- dendritic cells to CD1c+ dendritic cells were not significantly different between the three groups. CD40 (p=0.171), CD86 (p=0.037) and HLA-DR (p=0.036) were less expressed in the PACL than the BLD group. Expression of CD40 (p=0.319), CD86 (p=0.036) and HLA-DR (p=0.085) were less expressed in the PACL than the PSqCL group, but the differences were only significant for CD86. Expression of co-stimulatory markers was not different between the PSqCL and BLD groups. Expression of markers for activated DCs were dramatically lower in the PACL group than in groups with other histology (CD40 (p=0.005), CD86 (p=0.013) HLA-DR (p=0.004). Conclusion: These results suggest the possibility that CD1c+ myeloid DCs participate in control of the tumor immunity system and that low expression of markers results in lack of an immune response triggered by dendritic cells in adenocarcinoma of the lung.

Current Status of Respiratory Care in Korean Intensive Care Units (국내 중환자실내 호흡치료의 현황)

  • Park, So-Yeon;Kim, Tae-Hyung;Kim, Eun-Kyung;Shim, Tae-Sun;Lim, Chae-Man;Lee, Sang-Do;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong;Koh, Youn-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.49 no.3
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    • pp.343-352
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    • 2000
  • Backgrounds : Respiratory care for patients in intensive care units (ICUs) has been performed mainly by nurses in Korea. However, the current status of respiratory care in the Korea ICUs is not well known. Respiratory care and the methods of delivery in ICUs were surveyed. Method : A confidential questionnaire was distributed to the head nurses working the ICUs at 117 hospitals in Korea. One hundred hospitals returned the questionnaires, for a response rate of 85%. The hospitals were divided into three groups : Main university hospitals (MUH), university associated hospitals (UAH), and general hospitals (GH) Result : Eighteen units of 66 units in MUH and 35 units of 58 units in GH were organized as a general ICUs. The percentage of ICUs with full-time doctors was 47.1%. The nurses usually delivered respiratory care spending from 1 to 4 h during their 8 h of working time. Although the respondents felt that respiratory care should be delivered by trained respiratory therapists, these therapists were not found at the hospitals. Most of the units performed percussion, tracheal suctioning, and positional changes. However, vibration and IPPB were less frequently performed in GH. Among oxygen supply apparatus, venturi mask and T-piece were not frequently used in GH. GH applied a noninvasive ventilator mode less frequently than MUH and UAH. The percentage of Swan-Ganz catheter monitoring was only 21.4% in GH. Conclusion : Respiratory care for patients in the Korean ICUs was provided by nurses on the whole. In addition, there were many differences in the level of respiratory care according to the type of hospital. To overcome the current problems revealed, an effective in-hospital training program for the development of full-time respiratory care therapists should be established urgently in Korea.

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The Effects of Ethylacetate Fraction of Sanguisorba officinalis L. on Experimentally-induced Acute Gastritis and Peptic Ulcers in Rats (지유가 흰쥐의 급성위염 및 소화성 궤양에 미치는 영향)

  • Lee, Jae-Joon;Choi, Hyun-Suk;Lee, Jeong-Hwa;Jung, Chang-Joo;Lee, Myung-Yul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.10
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    • pp.1545-1552
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    • 2005
  • Sanguisorba officinalis L. has been used as a traditional remedy for arthritis, neuralgia, diarrhea, vomiting, gastric ulcer and gastro-intestinal disorders. This study was performed to investigate the protective effects of ethylacetate fraction of Sanguisorba officinalis L. ethanol extract (SOE) on the gastric mucosal damage and gastric ulcer induced by HCI-ethanol, indomethacin, Shay-ligation method, restraint and water-immersion stress, and cysteamine in rats. The experiment animals were divided into four groups: a negative control group (CON), positive control group (cimetidine 100 mg/kg-CMT or omeprazol 100 mg/kg administrated group-OMT), SOE 200 mg/kg administrated group (SOL) and SOE 400 mg/kg administrated group (SOH), respectively. Rats were given an oral or intraduodenal administration of SOE, and all SOE treatment groups compared with the CON significantly inhibited HCI-ethanol-induced acute gastritis and indomethacin-induced gastric ulcers in dose-dependent manner, of which effects were lower in a positive control drug (CMT). The inhibition rates ($\%$) on the acute gastritis induced by HCI-ethanol and the gastric ulcers induced by indomethacin in rats, 17.66$\%$ and 48.28$\%$ in SOL, 21.71$\%$, and 51.08$\%$ in SOH, and 47.26$\%$ and 58.26$\%$ in CMT compared with CON, respectively, In pylorus ligated rats, the groups of SOE showed decreases in the volume of gastric secretion and acid output. However, no significant differences were observed in the pepsin activity between treated groups . In addition, SOH also depressed gastric ulcers induced by restraint and water-immersion stress and duodenal ulcers induced by cysteamine. These results suggest that Sanguisorba officinalis L. has remarkable antigastric ulcer effects and could be developed as a new antigastric ulcer agents.

Studies on the Desertification Combating and Sand Industry Development(IV) - Technology Development for Sanddune Fixation and Sandy Land Conservation in China - (사막화방지(沙漠化防止) 및 방사기술개발(防沙技術開發)에 관한 연구(硏究)(IV) - 중국(中國)의 사구고정(沙丘固定) 및 방사공법분석(防沙工法分析) -)

  • Woo, Bo-Myeong;Lee, Kyung-Joon;Choi, Hyung-Tae;Lee, Sang-Ho;Park, Joo-Won;Wang, Lixian;Zhang, Kebin;Sun, Baoping
    • Journal of Korean Society of Forest Science
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    • v.90 no.3
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    • pp.277-294
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    • 2001
  • This study is aimed to analyze and to evaluate the technology development for sanddune fixation and sandy land conservation in China, resulting from the project of "Studies on the desertification combating and sand industry development". There are various types of sanddunes, including shrub-bunch type, dendritic, honey combed lattice, crescentic, parabolic, pyramid, complex and irregular types, domed, and so on. The height distribution ratios of these sanddunes are 13% of less than 5m, 17% of 6~10m, 18% of 11~25m, 14% of 26~50m, 28% of 51~100m, 10% of more than 100m, and so on. In dry land of China, shifting direction of the sanddune is mainly varying with main direction of wind, but types of shifting sanddunes have many differences in accordance with region, topography, size and shape of sanddunes. The main sanddune fixation technologies could be divided into the bio-ecological measures, physical measures and chemical measures. The bio-ecological measures include such vegetation measures as shrub-grasses measures, sandbreaks between sand dunes, sand fixation shelterblets and establishment of farmland shelterbelts, etc. The physical measures include establishment of high-sanddune stabilization walls and low-sanddune stabilization walls, sanddune fixation levees and coverage method with sediment clay, etc. The chemical measures include fixation-materials spraying and synthetical liquid spraying methods, etc. Besides, irrigation and sand settlement measures, shifting sand trapping channel, ditchsand fixation measures, etc. have been effectively applied.

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The Effects of High-intensity Combined Training Program on Cardiorespiratory Function, Isokinetic Trunk Strength and Anaerobic Power of Canoe Athletes (고강도 복합 훈련 프로그램이 카누선수의 심폐기능, 체간 등속성 근력과 무산소성 파워에 미치는 영향)

  • Jung, Jong-Hwan
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.1
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    • pp.17-27
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    • 2020
  • The purpose of this study is to confirm the effects of a 6-week high-intensity combined training program on canoe athletes' cardiorespiratory function, isokinetic trunk strength, and anaerobic power. For the purpose of this study, the high-intensity combined training program was applied to 9 high-school canoe athletes. The high-intensity combined training program consists of aerobic exercise performed 2 times a week (Tuesday and Thursday), anaerobic exercise performed 3 times a week (Monday, Wednesday, and Friday), and flexibility exercise performed 5 times a week. The core of the high-intensity combined training program was the anaerobic training program performed with 100% weight for repetition; otherwise, the existing training method was divided into the percentage (%) of the 1RM. The aerobic exercise and the gym ball exercise are performed subsidiarily. Results showed that there was a statistically significant difference in height and muscle mass, whereas there was no statistically significant difference in weight, body fat percentage, and BMI followed by the high-intensity combined training program. There were statistically significant differences in maximum oxygen uptake and total exercise time. The angular velocity of 30°/sec showed a statistically significant difference in the peak torque item of flexors only. Also, the angular velocity of 120°/sec showed a statistically significant difference in the total work item of extensors only; however, there was no statistically significant difference in all the items of peak power, average power, and peak drop. In conclusion, it seems that the high-intensity combined training program may be applied as a training program for enhancing canoe athletes' performance. For further studies, more than 6 weeks training program with more participants would show improved results of isokinetic strength and anaerobic power in athlets.

Effect of Omentum, Pleura, Diaphragm on Tracheal Autograft Survival (자가이식기관의 생존에 필요한 장막, 흉막, 횡격막의 역할 분석)

  • Keum, Dong-Yoon
    • Journal of Chest Surgery
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    • v.38 no.7 s.252
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    • pp.461-467
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    • 2005
  • Pleura, diaphragm, pericardial fat pad, intercostal muscles and omentum can be used to protect and revascularize the bronchial suture line of tracheal transplantation, lung transplantation and pulmonary resection. The purpose of the present study is to compare the influence of the pleura, diaphragm and omentum in survival of isolated tracheal segments in the experimental animals. Material and Method: Sprague-Dawley rats weighing 250- 350g were used. The animals were divided in three groups; the pleura, omentum and diaphragm. Following intraperitoneal anesthesia, endotracheal intubation was performed. Then the trachea was exposed. A three-ring sec- tion of cervical trachea was excised. The resected trachea was implanted at each sites. After 2 weeks, rats were sacrificed. Histopathological examination of the tracheal segments was performed. For comparison of each groups, histopathological viability of resected tracheal segment was scored by three tissue layers; epithelium, submucosa, and cartilage. The results were presented as average score. Result: In histopathological examination, submucosa and cartilage using tracheal segment necrosis scoring system. The pleural group showed well preserved tissue. There was minimal necrosis and inflammation compared with other groups. In the pleural group, tracheal necrosis scores were $2.17\pm0.983$at epithelium, $1.67\pm0.516$ at submucosa and $2.17\pm0.753$ at cartilage. At the omental group, scores were $1.00\pm0.00,\;1.60\pm0.548\;and\;1.80\m0.447$. In the diaphragmatic group, scores were $1.40:\pm0.894,\;2.40\pm0.547\;and\;2.20\pm0.447$. Total necrosis score were $6.00\pm1.789$ in the pleural group, $4.40\pm0.894$ in the omental group and $6.00\pm1.414$ in the diaphragmatic group. Conclusion: There were no significant viability differences in terms of total necrosis score for the viability of resected tracheal segment. But the best result was achieved in the omental group. Therefore, omental wrapping on tracheal graft site will be beneficial for the prevention of graft necrosis.