• Journal of Forest and Environmental Science
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• 제39권1호
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• pp.13-19
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• 2023

We investigated Soil respiration in Bluepine forest of western Bhutan, in relation to soil temperature, moisture content and soil pH and it was aimed at establishing variability in space and time. The Bluepine forest thrives in the typical shallow dry valleys in the inter-montane Bhutan Himalaya, which is formed by ascending wind from the valley bottom, which carries moisture from the river away to the mountain ridges. Stratified random sampling was applied and the study site was classified into top, mid, low slope and further randomized sample of n=20 from 30 m×30 m from each altitude. The overall soil respiration mean for the forest was found 2248.17 CO₂ g yr^-1 and it is ~613.58 C g yr^-1. The RS from three sites showed a marginal variation amongst sites, lower slope (2,309 m) was 4.64 μ mol m^-2 s^-1, mid slope (2,631 m) was 6.78 μ mol m^-2 s^-1 and top slope (3,027 m) was 6.33 μ mol m^-2 s^-1 and mean of 5.92 μ mol m^-2 s^-1, SE=0.25 for the forest. Temporal distribution and variations were observed more pronounced than in the space variation. Soil respiration was found highest during March and lowest in September. Soil temperature had almost inverse trend against soil respiration and dropped a low in February and peak in July. The moisture in the soil changed across months with precipitation and pH remained almost consistent across the period. The soil respiration and soil temperature had significant relationship R²=-0.61, p=0.027 and other variables were found insignificant. Similar relationship are reported for dry season in a tropical forest soil respiration. Soil temperature was found to have most pronounced effect on the soil respiration of the forest under study.

• Journal of the Korean Data and Information Science Society
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• 제27권6호
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• pp.1487-1498
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• 2016

관리도를 사용하여 공정을 관리할 때, 일반적으로 공정 모수의 정확한 값은 알 수 없기 때문에 제1국면의 표본을 통하여 이를 추정해서 사용하고 있다. 또한 추정된 공정 모수를 이용하여 관리도를 설계하는 경우 관리한계는 관리상태에서의 런길이의 평균인 ARL (average run length)이 미리 지정한 값을 만족하도록 설정하고 있다. 그러나 런길이의 분포는 일반적으로 치우쳐져 있기 때문에, 런길이의 평균 대신 중위수를 사용하는 것이 바람직할 수 있다. 이 논문에서는 제1국면에서 추정한 모수를 사용하는 경우 부그룹의 크기에 따른 $\bar{X}$ 관리도의 성능에 대해 연구하였고, 이때 공정 평균에 대한 추정량은 전체 표본평균을 사용하고 공정 표준편차에 대해서는 5가지 추정량을 사용하여 이에 대한 영향을 살펴보았다. 기존 연구와 다른 점은 여러 가지의 부그룹 크기에 대해 모수 추정의 영향을 ARL 대신 런길이의 중위수인 MRL (median run length)에 기초하여 살펴보았으며, 두 가지 방법에 대해 그 결과를 비교하였다.

• 한국응용과학기술학회지
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• 제36권2호
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• pp.592-599
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• 2019

This study is to stabilize insoluble and unstable active ingredient which is Idebenone (INCI name: hydroxydecyl ubiquinone) in a multi-lamellar vesicle (MLV) and to stabilize it in the skin care cosmetics. Idebenone is good effective raw material in the treatment of Alzheimer's disease in the medical field and a powerful antioxidant in dermatology. It is well known as a substance that inhibits the formation of melanin and cleans the skin pigment. However, it did not dissolve in any solvent and it was difficult to apply in cosmetic applications. Niosome vesicle was able to develop a nano-particle by making a multi-layer of idebenone encapsulated with a nonionic surfactant, hydrogenated lecithin and glycine soja (soybean) sterols and passing it through a high pressure microfluidizer. Idebenone niosome vesicle (INV) has been developed to have the ability to dissolve transparently in water and to promote transdermal penetration. The appearance of the INV was a yellowish liquid having specific odor, and the particle size distribution of INV was about 10~80 nm. The pH was 5~8 (mean=6.8). This capsulation with idebenone was stored in a $45^{\circ}C$ incubator for 3 months and its stability was observed and quantitatively measured by HPLC. As a result, the stability of the sample encapsulated in the niosome vesicle (97.5%) was about 66.3% higher than that of the non-capsule sample of 32.5%. Idebenone 1% INV was used for the efficacy test and clinical trial evaluation as follows. The anti-oxidative activity of INV was 38.2%, which was superior to that of 12.8% tocopherol (control). The melanin-reducing effect of B16 melanoma cells was better than INV (17.4%) and Albutin (control) (9.6%). Pro-collagen synthesis rate was 128.2% for INV and 89.3% for tocopherol (control). The skin moisturizing effect was 15.5% better than the placebo sample. The elasticity effect was 9.7% better than the placebo sample. As an application field, INV containing 1% of idebenone is expected to be able to develop various functional cosmetic formulations such as skin toner, ampoule essence, cream, eye cream and sunblock cream. In addition, it is expected that this encapsulated material will be widely applicable to emulsifying agents for skin use in the pharmaceutical industry as well as the cosmetics industry.

• 대한소아치과학회지
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• 제37권2호
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• pp.193-201
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• 2010

유아기 우식증은 유아와 어린이에 생긴 우유병 우식증 및 다발성 우식증을 포함한 좀 더 포괄적인 명칭으로, 이전 연구들에서 유아기 우식증이 어린이의 신체 성장에 영향을 미친다고 보고된 바 있다. 이번 연구의 목적은 유아기 우식증이 어린이의 신체 성장에 미치는 영향을 연령대 별 및 우식 이환 정도에 따라 평가하는 것으로, 신체 성장 평가 지표로 신장과 체중을 사용 하였다. 연세대학교 치과대학병원 소아치과에 내원한 환자를 유아기 우식증에 이완된 실험군과 이완되지 않은 대조군으로 나누어 평가하였다. 환자의 연령을 12개월 단위로 나누고, 각 연령대 별로 유아기 우식증이 어린이 신장과 체중에 미치는 영향을 평가하였다. 대조군과 실험군의 연령별 성장 백분위 분포도를 비교하기 위해 2007년 대한민국 질병관리본부에서 공포한 표준성장도표를 사용하였다. 대조군과 실험군 간의 표준 신장 및 체중을 비교하기 위해 two-sample T test를 사용하였고, 두 그룹 간의 성장 백분위 분포도를 비교하기 위해 Likelihood Ratio Chi-square test를 사용하였다. 대조군과 ECC군 사이의 평균 신장 및 체중의 차이를 비교해본 결과 남자와 여자 어린이에서 공통적으로 나타나는 경향으로 통계학적 유의성이 항상 있진 않았으나 만 3-4세를 기준으로 연령이 어릴수록 ECC군의 평균 신장 및 체중이 대조군에 비해 증가하며, 그 이후에는 ECC군의 평균 신장 및 체중이 오히려 대조군에 비해 감소하는 경향을 관찰할 수 있었다. 이러한 경향은 남자 어린이의 평균 체중을 제외한 다른 모든 경우에서 공통적으로 나타났다. 평균 신장과 체중의 유의할만한 차이를 가진 만 3-4세 이상의 군에서 성장 부전으로 정의되는 3 percentile 이하가 차지한 비율은 대조군에 비해 ECC군에서 더 높았다. 이상의 결과를 토대로 유아기 우식증이 어린이의 신체 성장에 부정적인 영향을 미칠 수 있으며, 연령에 따라 유아기 우식증에 의한 영향이 다른 형태로 나타남을 추측할 수 있었다.

• 한국발생생물학회지:발생과생식
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• 제14권4호
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• pp.261-268
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• 2010

As in the O. mykiss electrophoretic profiles of RNA, the signals of each RNA sample from 9 individual tissues such as liver, muscle, brain, heart, pituitary gland, kidney, intestine, spleen and gill similar to positive control were obtained. The tissue distributions of the complimentary DNA (cDNA) of O. mykiss four genes were analyzed using quantitative real-time PCR with primer sets for tissue expression analysis. In this rainbow trout species, author obtained bands of various sizes, ranged from 700 bp to 1,400 bp. A dissociation curve was made at the end of each run to make sure that there was no non-specific amplification. Supplementarily, the Ct of each DNA was compared. The Ct values of vinculin with rainbow trout tissues were determined in a manner similar to those for agouti-related protein (AgRP) and melanocortin receptors (MC4R I and MC4R II). Further, obtained Cts for standard curve of each DNA were affected by specific product (vinculin, AgRP and MC4R II genes). After several experiments with four individual genes of rainbow trout, author estimated a variation ratio of the mean Ct value of the DNA extracted using the comparative CTt method was 37.27, and the standard deviation was 5.33. The correlation coefficient between the Ct values and the concentration of cDNA was -0.98, -0.99, -0.91 and -0.86, respectively (vinculin, AgRP, MC4R I and MC4R II genes). Since this correlation showed high linearity, the straight line obtained was used as a standard for the O. mykiss tissues reared in aquarium. A PCR efficiency of 100% is ideally achieved when the slopes are close to the theoretical value of -3.31. According to quantification method, the results of quantification are strongly affected by the DNA fragmentation. The size of most DNA fragments obtained from various tissues of rainbow trout used in the experiment was approximately 100 bp. According to the four slopes, an efficiency of nearly 100% was estimated for four genes detection methods. Additionally, further analysis with more individuals and primers will be required to fully establish optimization in rainbow trout.

• 재활간호학회지
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• 제3권2호
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• pp.212-227
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• 2000

The purpose of this study was to investigate the patterns of alternative therapy and to describe the characteristics of cancer patients used alternative therapy. The sample of this study were 232 consisted of cancer patients who visited at Pusan National University Hospital, Dong-a, Kosin University Hospital. The data were gathered from August, 1 to October, 30 1999 and analyzed by using SPSSWIN program for frequency, percentile and $X^2$-test. The important results of this study are as follows. 1. In population-sociological characteristics, sexual distribution showed female 52.6%, and the male 47.4%, age distribution showed that more than 60year old group are most as 31.5%. 2. In the disease characteristics, colon and rectal cancer patients were most as 19.0%. In the type of pain, the most of subjects were "dully pain" as 25.4%. In the pain level, 134 subjects complained pain, mean maximal pain score was $7.3{\pm}2.29$ in 10 points rating scale. 3. 132 patients (56.9%) among 232 cancer patients had used alternative therapy. The most common type of alternative therapy was dietary and nutritional therapy 44%, the place of use. home 43.2%, duration, less than 3 months, 56.8%. The most common motive was a recommendation by friends or family. The degree of satisfaction after the use of alternative therapy was high for 22.0%. 4. In the relation between general characteristic and utilization of alternative therapy, the only living area was showed a significant statistical differance($X^2$ = 4.070, P= .044). also in the relation between disease characteristic and utilization of alternative therapy, morbidity periods, the size of higher pain, the type of treatment were showed a significant statistical differance($X^2$= 7.964, 7.303, 3.565, P=.044, .026, .042). In conclusions, these findings indicate that cancer patients use various complementary and in alternative therapy. therefore, suggested that medical doctors or nurses verify the true effects or side-effects from the most common complementary or alternative therapies through experiments.

• 한국의류학회지
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• 제12권3호
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• pp.351-361
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• 1988

The purpose of this study was to investigate the relationships between fashion style adoption and consumers' demographic characteristics, selection criteria and use of fashion information sources respectively and find out how their concerned variables influenced high fashion style adoption. For this study, the questionnaire was administered to a sample of 554 female adults in Kwangju. frequency distribution, Mean, Pearson's Correlation, Analysis of variance and Path Analysis were used fer the statistical analysis. The results obtained were as followers. 1) Level of fashion style adoption showed a normal distribution like a wave. 2) Consumer's demographic characteristics variables, such as age, educational level and income significantly associated with fashion style adoption. Younger consumers adopted tile high fashion style 41)an more aged consumers. while consumers in higher educational and income level adopted high fashion style than consumers in lower. 3) Among individuality, conformity, practicality and economy in selection criterias, only individually and practicality associated with fastion style adoption in clothing purchase. In the case of the high fashion style adoption, purchasing with individuality was increased, while purchasing with practicality was decreased. 4) The use of marketer dominated sources in fashion information sources significantlyassociated with fashion style adoption. In the case of high fashion style adoption, the use of marketer dominated and neutral information sources was higher. 5) The use of marketer dominated information sources had a main effect on high fashion style adoption in clothing purchase. Especially in the group composed of college students and occupational women, individuality and praticality as selection criterias came to be important effects. While in the group composed of housewives and non-occupational single women, age, educational level and income came to be important effects.

• 대한원격탐사학회지
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• 제15권3호
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• pp.195-208
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• 1999

위성영상 분류작업에서 분류클래스에 대한 샘플화소의 대표성은 분류 정확도에 많은 영향을 미친다. 따라서, 통계적 영상분류방법에서는 분류 기법 자체보다 분류 확률을 결정하는 트레이닝 단계, 즉 샘플화소의 최적화가 필요하다. 본 연구에서는 SPOT XS, LANDSAT TM을 이용한 위성영상 화소분류작업에서 분류 이전단계, 즉 샘플화소의 정규성을 계산하여, 정규성에 악영향을 미치는 화소를 객관적 기준으로 조정하였다. 정규화과정을 위한 유전자 알고리즘 적용의 생존확률 평가함수로 다변량 Q-Q plot의 상관계수와 트레이닝의 분산값을 고려하였으며, 5% 유의수준을 적용하였다. 연구결과, 실험대상지역의 경우, 유전자 알고리즘을 이용한 트레이닝 정규화 결과가 대부분의 클래스에 대하여 그 평균과 분산을 모집단에 근사시키고 있다는 것을 입증하였고, 해당 클래스의 모집단 분포를 예측할 수 있는 가능성을 제시하였다.

• Journal of Preventive Medicine and Public Health
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• 제27권3호
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• pp.569-579
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• 1994

The genetically determined ability to metabolize debrisoquine (DBR) is related to risk of lung cancer and DBR hydroxylation exhibits wide inter-individual variation. In this study, 100 korean adults were tested for their ability to metabolize DBR. The DBR metabolic phenotype were determined by metabolic ratio (MR, DBR / 4-HDBR) which is the percent dose excreted as unchanged DBR divided by the percent dose excreted as 4-hydroxyebrisoquine(4-HDBR) in a aliquot of an eight hour urine sample, after 10mg DBR test dose administration. Analysis was performed on a capillary gas chromatograph fitted with electron capture detector. The results were as follows; 1 Geometric mean of DBR MR was 0.32 in male,0.27 in female,0.30 in total and the distribution of log (MR) was seemed to follow normal distribution. 2. Metabolic ratio of DBR was higher in non-smoker and non-drinker than in smoker and drinker without any statistically significant difference. 3. None of personal factors was significantly related to DBR MR except age. 4. The DBR metabolic phenotype was extensive metabolizer(EM) 93, intermediate metabolizer(IM) 7 by traditional method and EM 98, IM 3 by Caporaso's method. The poor metabolizer (PM) phenotype was not found by either method. 5. Maximal expected PM phenotype was 0.36% by traditional method and 0.04% by Caporaso's method.

• 응용통계연구
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• 제27권7호
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• pp.1163-1170
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• 2014

간헐적인 패널 시계열 자료의 개념과 구조를 소개하고, 간헐적인 패널 시계열 자료의 모형으로 간헐적인 패널 1차 자기회귀 모형을 고려하였다. 간헐적인 패널 1차 자기회귀 모형의 동질성 검정을 위하여 Wald 검정통계량을 제안하고, 그 극한분포를 제시하였다. 또한 동질성이 만족되는 경우 시점 별 평균을 이용하여 종합한 자료로 모형을 적합하였다. 이 모형의 동질성 검정 통계량의 극한분포가 $^x2$분포에 잘 따르는지를 알아보기 위해 모의실험을 실시하고, 실제 자료 분석으로 지역별 월별 Mumps 자료에 간헐적인 패널 1차 자기회귀 모형을 적합하여 동질성 검정을 수행한 결과 동질성을 만족하였다. 동질성이 만족된 지역별 월별 Mumps 자료를 시점 별 평균을 이용하여 종합하고 1차 자기회귀 모형으로 적합하였다.