• International Journal of Quality Innovation
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• v.5 no.2
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• pp.106-121
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• 2004

This paper investigates customer knowledge management activities of Taiwan's plastic industries. The results demonstrate that the bulk of customer knowledge comes from data related to customer purchase orders and complaints. Furthermore, marketing, production, and research and development are the main departments that developed and reuse customer knowledge. The benefits derived from knowledge management for enterprises do not vary with the position of the vendor on the business scope. In addition, the benefits derived by customers from knowledge management are directly related to the benefits gained by the five major business functions, while the benefits derived from the customer knowledge management are also directly related to customer satisfaction. Summarizing the above results, an Acquisition-Development-Reuse (ADR) model is proposed and can provide the enterprises with a systematic reference model when the business attempts to construct a customer knowledge management system.

• Journal of Korean Society for Quality Management
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• v.21 no.2
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• pp.71-84
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• 1993

Currently the problem of air pollution caused by the motor vehicle emission is one of the most serious problems to be solved. Thus we needed the vehicle emissions audit procedure and technical innovation constraining the motor vehicle emission. The Korean Environmental Protection Agency currently audits automobiles for emissions compliance at assembly plants with multiple attribute multiple staged sampling plans. In order to establish the more reasonable audit procedure, the multiple staged sampling plan designed in this paper has been applied to the domestic vehicles by analyzing the statistic characteristics of the emission distribution. This paper summarizes the auditing procedure and develops methods for determining its statistical characteristics. Specifically, we consider how to evaluate a multiple staged sampling plan, give a procedure that efficiently estimates attribute-type probabilities from multivariate variables-type data, and quantify the effect of tightening the acceptable quality level of the sampling plan. As a result it can be proved that this audit procedure is the reasonable plan minimizing the AQL (Acceptable Quality Level) and is to be used effectively for the auditing procedure constraining the injurious gasses of the motor vehicles.

• Journal of the Korean Operations Research and Management Science Society
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• v.27 no.2
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• pp.81-96
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• 2002

Telecommunication services are distinctive in that their adoptions are influenced by network effect resulting in 'the late take-off phenomenon' and the 'critical mass' problem. In this paper we examined, so called, 'the late take-off phenomenon' in the diffusion process of telecommunication services. We compared the parameters of the diffusion process of consumer durables with those of fax services in the US and Korea. By analyzing the parameters of a new diffusion model based on the threshold model proposed by Markus, we found that 'the late take-off phenomenon' resulted from the low heterogeneity of the threshold distribution for the potential adopters. A simulation approach was proposed for the theoretical implication of the 'critical mass' problem in the start-up telecommunications services.

• International Journal of Quality Innovation
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• v.2 no.1
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• pp.69-86
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• 2001

The economic design of control charts has been researched for over four decades since Duncan proposed the concept in 1956. Few studies, however, have focused attention on the economic design of a moving average (MA) control chart. An MA control chart is more effective than the Shewhart chart in detecting small process shifts [9]. This paper provides an economic model for determining the optimal parameters of an MA control chart with multiple assignable causes and two failures in the production process. These parameters consist of the sample size, the spread of the control limit and the sampling interval. A numerical example is shown and the sensitivity analysis shows that the magnitude of shift, rate of occurrence of assignable causes and increasing cost when the process is out of control have a more significant effect on the loss cost, meaning that one should more carefully estimate these values when conducting an economic analysis.

• Journal of Korean Society for Quality Management
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• v.19 no.2
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• pp.63-77
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• 1991

Currently the problem of air pollution caused by the motor vehicle emission is one of the most serious problems to be solved. Thus we needed the inspection method and technical innovation constraining the motor vehicle emission. In order to establish the more reasonable certified test, the multivariate sequential rectifying inspection plan designed in this paper has been applied to the domestic vehicles by analyzing the statistic characteristics of the emission distribution. This inspection method is designed to satisfy the evaluation measure constraining domestic vehicle emission, and it serves the defect rectifying system and performance certification of catalytic converts. As the prior parameter for the domestic vehicles, we used the data for the catalytic converts which passed the certified test excuted by the EPK. For the case of engine test, we used those data which passed the certified test of domestic vehicles. The multivariate sequential rectifying inspection plan of the vector parameter is able to minimize the average sample number and increase the pass probability of operating characteristic curve.

• International Journal of Quality Innovation
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• v.7 no.2
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• pp.83-96
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• 2006

In this paper, fuzzy hierarchical analysis (FHA) is used to explore the process by which the criteria weights of the Taiwan National Quality Award (TNQA) are assigned by TNQA committee members. Each member is allowed to employ fuzzy scales in place of exact scales. Each pairwise comparison of criteria is made through a questionnaire from each TNQA committee member. The membership function of trapezoidal fuzzy numbers is introduced to specify TNQA committee members' intentions. After FHA, the reasonable range of each criterion weight of TNQA is determined. The current criteria weights of TNQA are properly verified.

• Journal of Ginseng Research
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• v.45 no.6
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• pp.734-743
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• 2021

Background: The underlying mechanisms of the potential tumor-suppressive effects of ginsenoside Rh2 are complex. N6-methyladenosine (m6A) RNA methylation is usually dysregulated in cancer. This study explored the regulatory effect of ginsenoside Rh2 on m6A RNA methylation in cancer. Methods: m6A RNA quantification and gene-specific m6A RIP-qPCR assays were applied to assess total and gene-specific m6A RNA levels. Co-immunoprecipitation, fractionation western blotting, and immunofluorescence staining were performed to detect protein interactions and distribution. QRT-PCR, dual-luciferase, and ChIP-qPCR assays were conducted to check the transcriptional regulation. Results: Ginsenoside Rh2 reduces m6A RNA methylation and KIF26B expression in a dose-dependent manner in some cancers. KIF26B interacts with ZC3H13 and CBLL1 in the cytoplasm of cancer cells and enhances their nuclear distribution. KIF26B inhibition reduces m6A RNA methylation level in cancer cells. SRF bound to the KIF26B promoter and activated its transcription. SRF mRNA m6A abundance significantly decreased upon KIF26B silencing. SRF knockdown suppressed cancer cell proliferation and growth both in vitro and in vivo, the effect of which was partly rescued by KIF26B overexpression. Conclusion: ginsenoside Rh2 reduces m6A RNA methylation via downregulating KIF26B expression in some cancer cells. KIF26B elevates m6A RNA methylation via enhancing ZC3H13/CBLL1 nuclear localization. KIF26B-SRF forms a positive feedback loop facilitating tumor growth.

• Journal of Technology Innovation
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• v.22 no.4
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• pp.165-198
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• 2014

The national R&D performance evaluation system in Korea has been influenced by 'New Public Management' since the 1980s. The 1997 IMF crisis in Korea has necessitated the overhaul of S&T policy strategies in Korea. Reflecting this, effective distribution and utilization of S&T investment and resources has emerged as a crucial policy agenda, while expansionary investment in S&T maintained. During the period of 1999-2005, the R&D evaluation has been more focused on the input side and execution processes than on the results of R&D. Evaluation results were to be reflected in the budgeting of national R&D, but there were some disputes over how to make use of evaluation results between the budgeting ministry and the evaluation agency partly because they were two separate entities. After the advent of the new government(1998-2003) which advocated 'science and technology-oriented society', the national R&D evaluation system has evolved through a new legislation, the Performance Assessment Act, and the establishment of Science & Technology Innovation Agency to build up the unique framework for national R&D evaluation differentiated from the assessment system for general government investment programs. Most recently, due to 'Comprehensive Improvement Plan' in 2013, various components of national R&D evaluation seem to move on a new evolutionary track. For example, different types of evaluation are being developed and tried in accordance with differing evaluation goals, and the individual ministries and the research councils has got more enhanced autonomy and responsibility regarding R&D evaluation. So-called 'tailored' evaluation methods, taking into consideration the characteristics of programs and institutes / organizations to be evaluated, are now being tried. Competences of evaluation experts and agencies has also to be improved and strengthened.

• Bulletin of the Korean Chemical Society
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• v.34 no.2
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• pp.447-452
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• 2013

In this study we report a new method for the synthesis of a silica monolithic column bed with bimodal pores (throughpores and mesopores). The template induced synthesis method was used to direct bimodal pores simultaneously instead of the usual post base-treating method. Block polymer Pluronic F127 was chosen as a dual-function template to form hierarchically porous silica monolith with both macropores and mesopores. This is a simplification of the method of monolithic column preparation. Poly(ethylene glycol) was used as a partial substitute for F127 can effectively prevent shrinkage during the monolith aging process without losing much surface area (944 $m^2/g$ to 807 $m^2/g$). More importantly, the resultant material showed a much narrower mesopore size (centered at 6 nm) distribution than that made using only F127 as the template reagent, which helps the mass transfer process. The solvent washing method was used to remove the remaining organic template, and it was proved to be effective enough. The new synthesis method makes the fabrication of the silica monolithic column (especially capillary column) much easier. All the structure parameters indicate that monolith PFA05 prepared by the above method is a good material for separation, with the merits of much higher surface area than usual commercial HPLC silica particles, suitable mesopore volume, narrow mesopore size distribution, low shrinkage and it is easily prepared.

• Geophysics and Geophysical Exploration
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• v.17 no.2
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• pp.49-57
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• 2014

3D magnetic inversion, based on the assemblage of 2D forward modeling and inversion as a practical technique to reflect the a priori information, was conducted to investigate the spatial distribution features of black-shale related and pyrometamorphic uranium deposit and several lithological units of Ogcheon Super Group in an area of Geumsan. By using the 3D visualization technique with suitable susceptibility interval and horizontal slice map, the spatial distribution of magnetic susceptibility corresponded to the black shale related uranium bearing lithological units, Black Slate member was well coincided with a information of uranium deposit. Also, even though it is indirect indicator for the detetction of uranium deposits interbedded in Gray Hornfels member, spatial susceptibility distribution which shows the south-east magnetic linearment corresponding to the Majeon-ri formation and Dark Gray Slate were matched well. From this investigation, we inferred that maximum depth extension which Black Slate member can be separately recognized with respect to adjacent Dark Gray Slate with strong magnetic susceptibility anomaly is about 150m with reference elevation level of 306m. In addition, Majeon-ri formation located south of Black Slate member revels relatively high magnetic susceptibility range but shows high spatial susceptibility fluctation. And, as an intrusive rocks, Jurassic Biotite Granite shows relatively low magnetic susceptibility characteristics. On the contrary, Cretaceous granite distributed in soutthern part of the study area shows the relatively high susceptibility distribution.