• Title/Summary/Keyword: Distribution Innovation#2

Search Result 244, Processing Time 0.024 seconds

Panax ginseng total protein promotes proliferation and secretion of collagen in NIH/3T3 cells by activating extracellular signal-related kinase pathway

  • Chen, Xuenan;Wang, Manying;Xu, Xiaohao;Liu, Jianzeng;Mei, Bing;Fu, Pingping;Zhao, Daqing;Sun, Liwei
    • Journal of Ginseng Research
    • /
    • v.41 no.3
    • /
    • pp.411-418
    • /
    • 2017
  • Background: Recently, protein from ginseng was studied and used for the treatment of several kinds of diseases. However, the effect of ginseng total protein (GTP) on proliferation and wound healing in fibroblast cells remains unclear. Methods: In this study, cell viability was analyzed using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. Cell cycle distribution was analyzed by flow cytometer. The levels of transforming growth factor ${\beta}1$, vascular endothelial growth factor, and collagens were analyzed by enzyme-linked immunosorbent assay and immunofluorescence staining. The expressions of cyclin A, phosphorylation of extracellular signal-related kinase (p-ERK1/2), and ERK1/2 were analyzed by Western blotting. Results: Our results showed that GTP promoted cell proliferation and increased the percentage of cells in S phase through the upregulation of cyclin A in NIH/3T3 cells. We also found that GTP induced the secretion of type I collagen, and promoted the expression of other factors that regulate the synthesis of collagen such as transforming growth factor ${\beta}1$ and vascular endothelial growth factor. In addition, the phosphorylation of ERK1/2 at Thr202/Tyr204 was also increased by GTP. Conclusion: Our studies suggest that GTP promoted proliferation and secretion of collagen in NIH/3T3 cells by activating the ERK signal pathway, which shed light on a potential function of GTP in promoting wound healing.

Strategic Approaches to Solid Ranking International Journals: KODISA Journals (국제저널 육성 방향과 전망: KODISA Journals를 중심으로)

  • Youn, Myoung-Kil;Kim, Dong-Ho;Lee, Jong-Ho;Hwang, Hee-Joong;Lee, Jung-Wan
    • Journal of Distribution Science
    • /
    • v.12 no.6
    • /
    • pp.5-13
    • /
    • 2014
  • Purpose - The purposes of this editorial review are twofold: firstly, to introduce the four flagship international journals of the Korea Distribution Science Association(KODISA): the Journal of Distribution Science(JDS), the Journal of Industrial Distribution & Business(JIDB), the East Asian Journal of Business Management(EAJBM), and the Journal of Asian Finance, Economics and Business(JAFEB), and secondly, to identify the direction of the KODISA journals and the roles and responsibilities of the editors of the KODISA journals. Research design, data, and methodology - To achieve the goals, firstly, this review paper addresses the current progress of the four KODISA journals: JDS, JIDB, EAJBM, and JAFEB. Secondly, this paper defines the aims and missions of the four KODISA journals. JDS publishes the articles of examining past, current, and emerging trends and concerns in the area of distribution science and economics, logistics and SCM, transportation, distribution channel management, distribution innovation and information technology, merchandising and procurement, distribution and marketing, consumer behavior, and manufacturing, wholesaling, and retailing. JDS publishes both quantitative and qualitative research as well as scholarly commentaries, case studies, book reviews and other types of reports relating to all aspects of distribution. JIDB publishes the articles of examining past, current, and emerging trends and concerns in the areas of industry and corporate behavior, industry policy making, industrial distribution and business, e-commerce, and service industry. EAJBM publishes empirical and theoretical research papers as well as scholarly commentaries, case studies, book reviews, and other types of reports relating to all aspects of East Asian business and economy. JAFEB publishes original research analysis and inquiry into the contemporary issues of finance, economics and business management in Asia, including Central Asia, East Asia, South Asia, Southeast Asia, and Middle East. The mission of JAFEB is to bring together the latest theoretical and empirical finance, economics and business management research in Asian markets. The audiences of the KODISA journals include higher education institutions, scholars, industry researchers and practitioners, scientists, economists, and policy makers throughout the world. The main mission of the KODISA journals is to provide an intellectual platform for international scholars, promote interdisciplinary studies in social sciences and economics, and become leading journals in the social science and economics category in the world. Thirdly, this paper addresses the current status of indexing in major databases of the KODISA journals, namely: Cabell's Directories, EBSCO, SCOPUS (Elsevier), and Social Sciences Citation Index® (SSCI, Thomson Reuters). Fourthly, this paper identifies the roles and responsibilities of the editors of the KODISA journals as the following: (1) Make sure that the journal be published in a timely manner and in international standards both in print and online versions. (2) Maintain the online homepage of the journal is always accessible to, and (3) Make sure that every article should go through a peer review process that meets international standards. Findings and conclusion - To accomplish the goals and missions of the KODISA journals, the editors of the KODISA journals must work together to publish high scholarly journals that meet international standards of journal publications.

A study of SCM strategic plan: Focusing on the case of LG electronics (공급사슬 관리 구축전략에 관한 연구: LG전자 사례 중심으로)

  • Lee, Gi-Wan;Lee, Sang-Youn
    • Journal of Distribution Science
    • /
    • v.9 no.3
    • /
    • pp.83-94
    • /
    • 2011
  • Most domestic companies, with the exclusion of major firms, are reluctant to implement a supply chain management (SCM) network into their operations. Most small- and medium-sized enterprises are not even aware of SCM. Due to the inherent total-systems efficiency of SCM, it coordinates domestic manufacturers, subcontractors, distributors, and physical distributors and cuts down on cost of inventory control, as well as demand management. Furthermore, a lack of SCM causes a decrease in competitiveness for domestic companies. The reason lies in the fundamentality of SCM, which is the characteristic of information sharing, process innovation throughout SCM, and the vast range of problems the SCM management tool is able to address. This study suggests the contemplation and reformation of the current SCM situation by analyzing the SCM strategic plan, discourses and logical discussions on the topic, and a successful case for adapting SCM; hence, the study plans to productively "process" SCM. First, it is necessary to contemplate the theoretical background of SCM before discussing how to successfully process SCM. I will describe the concept and background of SCM in Chapter 2, with a definition of SCM, types of SCM promotional activities, fields of SCM, necessity of applying SCM, and the effects of SCM. All of the defects in currently processing SCM will be introduced in Chapter 3. Discussion items include the following: the Bullwhip Effect; the breakdown in supply chain and sales networks due to e-business; the issue that even though the key to a successful SCM is cooperation between the production and distribution company, during the process of SCM, the companies, many times, put their profits first, resulting in a possible defect in demands estimation. Furthermore, the problems of processing SCM in a domestic distribution-production company concern Information Technology; for example, the new system introduced to the company is not compatible with the pre-existing document architecture. Second, for effective management, distribution and production companies should cooperate and enhance their partnership in the aspect of the corporation; however, in reality, this seldom occurs. Third, in the aspect of the work process, introducing SCM could provoke corporations during the integration of the distribution-production process. Fourth, to increase the achievement of the SCM strategy process, they need to set up a cross-functional team; however, many times, business partners lack the cooperation and business-information sharing tools necessary to effect the transition to SCM. Chapter 4 will address an SCM strategic plan and a case study of LG Electronics. The purpose of the strategic plan, strategic plans for types of business, adopting SCM in a distribution company, and the global supply chain process of LG Electronics will be introduced. The conclusion of the study is located in Chapter 5, which addresses the issue of the fierce competition that companies currently face in the global market environment and their increased investment in SCM, in order to better cope with short product life cycle and high customer expectations. The SCM management system has evolved through the adaptation of improved information, communication, and transportation technologies; now, it demands the utilization of various strategic resources. The introduction of SCM provides benefits to the management of a network of interconnected businesses by securing customer loyalty with cost and time savings, derived through the consolidation of many distribution systems; additionally, SCM helps enterprises form a wide range of marketing strategies. Thus, we could conclude that not only the distributors but all types of businesses should adopt the systems approach to supply chain strategies. SCM deals with the basic stream of distribution and increases the value of a company by replacing physical distribution with information. By the company obtaining and sharing ready information, it is able to create customer satisfaction at the end point of delivery to the consumer.

  • PDF

Quality Characteristics of Various Beans in Distribution (시중에 유통되는 콩의 종류에 따른 품질 특성)

  • Moon, Hye-Kyung;Lee, Soo-Won;Moon, Jae-Nam;Kim, Dong-Hwan;Yoon, Won-Jung;Kim, Gwi-Young
    • Journal of the East Asian Society of Dietary Life
    • /
    • v.21 no.2
    • /
    • pp.215-221
    • /
    • 2011
  • The goal of this study was to evaluate the quality characteristics of various beans in distribution. The quality characteristics investigated were proximate composition, color, free sugars, organic acids, amino acids, and minerals. Bean samples analyzed were white soybeans (Glycine max. (L.) Merrill), kidney beans (Phaseolus vulgaris var. humilis), black soybeans (Glycine max (L.) Merr.), black small soybeans (Rhynchosia nulubilis), sword beans (Canavalia gladiata), and green beans (Phaseolus vulgaris). The highest contents of crude fat and crude protein were 17.60${\pm}$0.14% for white soybeans, and 42.38${\pm}$0.15% for black soybeans, respectively. Higher color values compared to the other samples were $L^*$ (64.07${\pm}$0.97) for sword beans, $a^*$ (15.64${\pm}$0.48) for kidney beans, and $b^*$ (22.92${\pm}$0.09) for white soybeans. The highest contents of sucrose, oxalic acid, and malic acid in black small soybeans were 54.23 mg/g, 23.26 mg/100 g and 18.24 mg/100 g, respectively. Xylose, galactose, lactose, malonic acid, succinic acid, and lactic acid were not detected in the soybeans studied, whereas the glutamic acid content of soybeans ranged from 2.68 to 6.18 g/100 g. Levels of K and Mg contents in soybean were higher than those of the other minerals.

Development of Casting Furnace for Directional Solidification Ingot (잉곳의 방향성 응고를 위한 주조 로 개발)

  • Ju, Jin-Young;Lee, Seung-Jun;Baek, Ha-Ni;Oh, Hun;Cho, Hyun-Seob;Lee, Choong-Hun
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.13 no.2
    • /
    • pp.808-816
    • /
    • 2012
  • This paper is the study for the directional solidification of the ingot through the thermal analysis simulation and structural change of casting furnace. With the results of thermal analysis simulation, the silicon as a whole has reached the melting temperature as the retention time 80 min. The best cooling conditions showed at the upper cooling temperature $1,400^{\circ}C$ and cooling time 60min. The fabricated wafers showed the superior etching result at the grain boundary than that of existing commercial wafers. The FTIR measurements of oxygen and carbon impurities were not in the critical value for solar conversion efficiency. The NAA analysis of metal impurities were also detected the total number of 18 different metals, but the concentration distribution showed no significant positional deviations in the same position from the top to the bottom.

Analysis on Time Lag Effect of Firm's R&D Investment (기업 R&D 투자의 시차효과 분석)

  • Lee, Hun-jun;Baek, Chulwoo;Lee, Jeong-dong
    • Journal of Technology Innovation
    • /
    • v.22 no.1
    • /
    • pp.1-22
    • /
    • 2014
  • R&D investment also has a gestation period similar to other investments in economics. The gestation period originates from time lag effect of input and output. Thus it is necessary to consider time lag effects when analyzing the relationship between firms' R&D investment and R&D performance. The main objective of this research is to estimate the length of time lag effect of R&D investment. The Almon distribution lag model was applied to estimate the time lag effect. The firm level panel dataset was established from 2002 to 2009. The net value of R&D investment and the number of patent applications were used to measure R&D input and output, respectively. This method found the estimated time lag to be 1~2 years across all datasets. The same analyses were applied to chemical, metal, electronic, exact science, and machinery industries' data. And we found there were differences among sectors in regard to the time lag effect.

Population Allocation at the Building level for Micro-level Urban Simulation: A Case of Jeonju, Korea

  • Kim, Dohyung;Cho, Dongin
    • Asian Journal of Innovation and Policy
    • /
    • v.9 no.2
    • /
    • pp.223-239
    • /
    • 2020
  • It is important for urban planners and policy makers to understand complex, diverse urban demands and social structure, but this is not easy due to lack of data that represents the dynamics of residents at micro-geographical level. This paper explores how to create population data at at a micro-level by allocating population data to building. It attempted to allocate population data stored in a grid layer (100 meters by 100 meters) into a building footprint layer that represents the appearance of physical buildings. For the allocation, this paper describes a systemic approach that classifies grid cells into five prototypical patterns based on the composition of residential building types in a grid cell. This approach enhances allocation accuracy by accommodating heterogeneity of urban space rather than relying on the assumption of uniform spatial homogeneity of populations within an aerial unit. Unlike the methods that disaggregate population data to the parcel, this approach is more applicable to Asian cities where large multifamily residential parcels are common. However, it should be noted that this paper does not demonstrate the validity of the allocated population since there is a lack of the actual data available to be compared with the current estimated population. In the case of water and electricity, the data is already attached to an individual address, and hence, it can be considered to the purpose of the validation for the allocation. By doing so, it will be possible to identify innovative methods that create a population distribution dataset representing the comprehensive and dynamic nature of the population at the micro geographical level.

An Introduction of Management and Policy of Biological Resources (생물자원의 관리와 정책)

  • Cho, Soon-Ro;Seol, Sung-Soo;Park, Jung-Min
    • Journal of Korea Technology Innovation Society
    • /
    • v.11 no.2
    • /
    • pp.219-240
    • /
    • 2008
  • This paper aims to suggest a policy for biological resource based on a comprehensive understanding on biological resources. Biological resources are different from traditionally recognized viable organisms (Biodiversity) in ecosystems. Biological resources are culturable and replicable resources of living organisms such as tissues, cells and genes. Moreover, biological resources include human-derived biological materials. Biological resources is not simply a matter of science and technology. Biological resources should be dealt with as national resources. There are many international issues regarding biological resources, such as intellectual property rights (IPRs), safety on handling and distribution, material transfer agreements (MTAs) for mutual benefits and biological standards. Ethical debates are also being raised because biological resources are related with human-derived biological materials. Every nation has tendency to adopt its government policies to strengthen its sovereignty on biological resources and international cooperation. In addition, international linkages are essential for providing enhanced worldwide accessibility to biological resources. Japan has shown several international initiatives in the field of biological resources. Korea has just begun to design appropriate policies for the use and R&D of biological resources. Therefore, this paper suggests the following needs: 1) policy at the national level beyond the interests of researchers, 2) inter-ministerial coordination across government ministries, 3) expansion of scope and size of each BRC (Biological Resource Centers), and 4) building networks and systems such as national information center, representative centers by field, and each BRC.

  • PDF

Organizational-Economic Mechanism of Attracting Investment Resources in the Innovative Development of Regions in Teams of Sustainable Development

  • Krasnonosova, Olena;Perepeliukova, Olena;Papp, Vasyl;Doronina, Maya;Romaniuk, Mykhailo
    • International Journal of Computer Science & Network Security
    • /
    • v.22 no.2
    • /
    • pp.376-384
    • /
    • 2022
  • The article considers the features of the organizational-economic mechanism of attracting investment resources in the innovative development of regions in terms of sustainable development. Factors influencing the investment activity of regions in terms of sustainable development, including: institutional structure, intellectual capital, level of innovation infrastructure, business development, financial and credit component, level of human resources development, information environment, production development, environmental component. Factors influencing the attraction of investment resources in the regions are identified. The dynamics of changes in the volume of capital investments and foreign direct investment in Ukraine is analyzed. The regional features of the distribution of capital investments in the conditions of sustainable development are revealed. The essence of the main principles on the basis of which the organizational - economic mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development should be formed is analyzed. A set of measures to regulate the investment processes of the regions has been identified. The mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development is outlined. The results of activity of separate Agencies of regional development for 2020 in the direction of investment and innovation activity and increase of level of investment attractiveness of regions are analyzed. Important prerequisites for the effective implementation of the organizational-economic mechanism for attracting investment resources in the innovative development of regions in terms of sustainable development are identified. The main directions of directing the efforts of the organizational-economic mechanism to ensure the attraction of investment resources in the innovative development of regions in the context of increasing the level of investment activity in the regional aspect are substantiated.

Investment Priority and ImProvements in the Northeast Asia Logostics Hub Road Map (한국의 동북아 물류중심로드맵 투자우선순위와 개선방안)

  • Choe, Seok-Beom
    • Journal of Korea Port Economic Association
    • /
    • v.20 no.2
    • /
    • pp.187-216
    • /
    • 2004
  • Northeast Asia logistics hub strategy was undertaken by Korean Government to gain a national competitive advantage in Northeast Asia. Current Government has Northeast Asian Economic Hub Strategy including construction of SOC in Northeast Asia for promoting peace, promotion of formation of Northeast Asia Community, logistics hub, Financial hub and national innovation for R&D Cluster. To realize Northeast Asian logistics hub, the Northeast Asia logistics hub road map has undertaken as follows: expansion of logistics infra in Incheon Airport, Busan Port and Gwangyang Port, systematic improvements such as adjustment of investment distribution, special logistics companies, transparent customs in logistics transactions, logistics manpower, improvement of system supporting global logistics and attraction of international logistics companies to the logistics center, construction of seamless and paperless logistics information network, Northeast Asia railway infra. The purpose of this paper is to study investment priority and improvements in the Northeast Asia Logistics Hub Road Map and to contribute to gain the national competitive advantage as logistics hub in Northeast Asia

  • PDF