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Design of Decentralized Guidance Algorithm for Swarm Flight of Fixed-Wing Unmanned Aerial Vehicles (고정익 소형무인기 군집비행을 위한 분산형 유도 알고리듬 설계)

  • Jeong, Junho;Myung, Hyunsam;Kim, Dowan;Lim, Heungsik
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.12
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    • pp.981-988
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    • 2021
  • This paper presents a decentralized guidance algorithm for swarm flight of fixed-wing UAVs (Unmanned Aerial Vehicles). Considering swarm flight missions, we assume four representative swarm tasks: gathering, loitering, waypoint/path following, and individual task. Those tasks require several distinct maneuvers such as path following, flocking, and collision avoidance. In order to deal with the required maneuvers, this paper proposes an integrated guidance algorithm based on vector field, augmented Cucker-Smale model, and potential field methods. Integrated guidance command is synthesized with heuristic weights designed for each guidance method. The proposed algorithm is verified through flight tests using up to 19 small fixed-wing UAVs.

Effect of Nonylphenol on the Structure of Adrenal Cortex in F1 Generation Rats

  • Hee-Su Kim;Sung-Ho Lee
    • Development and Reproduction
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    • v.26 no.4
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    • pp.175-182
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    • 2022
  • Previous studies, including our own, indicate that distinct morphological changes in rodent adrenal cortex could be induced by exposure of endocrine disrupting chemicals (EDC). In the present study, we conducted histological analyses of adrenocortical substructure using a nonylphenol-treated F1 rat model. The adrenal weight of NP-5000 group was significantly declined in female rats (p<0.001), while the adrenal weights of NP-treated groups were not significantly changed in male rats. The thickness of zona glomerulosa layers of female rats in NP-5000 group was significantly declined (p<0.001) but zona fasciculata layers were not changed. The zona reticularis layers of NP-treated group were significantly thinner than those of control group (NP-50, p<0.05; NP-5000, p<0.01). In male adrenal glands, there was no significant change of zona glomerulosa layers in NP-treated groups while the thickness of zona fasciculata in NP-5000 group was significantly decreased (p<0.01). Like female rats, the thickness of zona reticularis in NP-treated groups was significantly decreased (NP-50, p<0.001; NP-5000, p<0.05). Present study demonstrated that the adrenal histology could be altered by low-dose NP exposure in F1 rats, and the effect might be sexually dimorphic. Further study will be helpful for understanding possible adrenal pathophysiology induced by EDC exposure, and EDC-related sexually dimorphic phenomena in rodent adrenals.

The Endocrine Control of Corpus Luteum Function (황체기능의 내분비 제어)

  • 성환후
    • Korean Journal of Animal Reproduction
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    • v.19 no.4
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    • pp.307-322
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    • 1996
  • The corpus luteum (CL) is formed by the action of a surge of luteinizing hormone (LH) on the pre-ovulatory follicle. Luteal cells derived from granulosa and theca interna cells continue to secrete progesterone for about two weeks. LH in domestic animals is essential for the normal secretion of progesterone at all stages of the luteal phase. For this process in the rodents, 20$\alpha$-hydroxysteroid dehydrogenase (20$\alpha$-HSD) is indispensable. 20$\alpha$-HSD is an enzyme to be a biologically inactive steroid. This enzyme plays a critical role in the regulation of the rat luteal function and reported to be present in steroid-producing tissues such as the testis and adrenal gland. We have purified 20$\alpha$-HSD and found two distinct 20$\alpha$-HSD molecules (HSD-1 and HSD-2). Their molecular weights are both estimated to be 33kd.The amino acid compositions of HSD-1 and HSD-2 are mostly similar, but there is a slight difference in the content of lysine. We demonstrated that 1) CL of previous generations contribute more to whole ovarian 20$\alpha$-HSD activity, 2) newly formed corpora lutea contain only 20$\alpha$-HSD-1 activity, and 3) old CL express activities of each HSD isozyme as shown in the luteal tissue of cycling rats on the day of diestrus where only degenerating old CL exist. The increase in 20$\alpha$-HSD activity identified seems to be related to the increase in the numbers of 20$\alpha$-HSD-positive cells. Interestingly, 20$\alpha$-HSD-1 activities were strongly found in the follicle fluids and theca interna cells by immunohistochemical study. Thus, the activity of 20$\alpha$-HSD may be related to a survival mechanism of those luteal cells and follicles remaining in the ovaries. Luteal cells arise from two sources. The small luteal cells are all of theca cell origin, while the large luteal cells are mainly of granulosa cell origin. CL of Korean Native Cattle, as those of other animal species, contains two morphologycally and functionally distinct luteal cell populations, such as small and large luteal cells as well as nonluteal cells. In all reproductive states except in the late luteal phase, the bovine CL also contained more small luteal cells than large luteal cells. Luteal tissue secretes a variety of growth factors (proteins) and the pattern of secretion changes during all stages of the luteal phase. These growth factors could be important in regulating the function of the bovine corpus luteum and may act in a potential endocrine autocrine and paracrine mechanisms. Therefore, further work has to be done to elucidate the role of growth factors in the ovary, especially in the corpus luterum. Interest should be focussed on interaction of these growth factors in the regulation of luteal cell and the localization of cytokine synthesis in differnet luteal cells.

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Identification of Autoantigens in Pediatric Gastric Juices

  • Hee-Shang Youn;Jin-Su Jun;Jung Sook Yeom;Ji Sook Park;Jae-Young Lim;Hyang-Ok Woo;Jung-Wook Yang;Seung-Chul Baik;Woo-Kon Lee;Ji-Hyun Seo
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.27 no.1
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    • pp.15-25
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    • 2024
  • Purpose: This study aimed to investigate the presence of autoantigens in the gastric juices of children. Methods: Gastric juice and serum samples were obtained from 53 children <15 years of age who underwent gastric endoscopy. Among these, 8, 22, and 23 participants were in the age groups 0-5, 6-10, and 11-15 years, respectively. These samples were analyzed using two-dimensional electrophoresis (2-DE), immunoblot analysis, and matrix-assisted laser desorption ionization-time of-flight mass spectrometry. Furthermore, we reviewed the histopathological findings and urease test results and compared them with the results of 2-DE and immunoblot analysis. Results: There were no statistically significant differences in urease test positivity, grades of chronic gastritis, active gastritis, or Helicobacter pylori infiltration of the antrum and body among the three age groups. Three distinct patterns of gastric juice were observed on 2-DE. Pattern I was the most common, and pattern III was not observed below the age of 5 years. Histopathological findings were significantly different among active gastritis (p=0.037) and H. pylori infiltration (p=0.060) in the gastric body. The immunoblots showed large spots at an approximate pH of 3-4 and molecular weights of 31-45 kDa. These distinct, large positive spots were identified as gastric lipase and pepsin A and C. Conclusion: Three enzymes, which are normally secreted under acidic conditions were identified as autoantigens. Further investigation of the pathophysiology and function of autoantigens in the stomach is required.

Hybrid Minimum Spanning Tree Algorithm (하이브리드 최소신장트리 알고리즘)

  • Lee, Sang-Un
    • The KIPS Transactions:PartA
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    • v.17A no.3
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    • pp.159-166
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    • 2010
  • In this paper, to obtain the Minimum Spanning Tree (MST) from the graph with several nodes having the same weight, I applied both Bor$\dot{u}$vka and Kruskal MST algorithms. The result came out to such a way that Kruskal MST algorithm succeeded to obtain MST, but not did the Prim MST algorithm. It is also found that an algorithm that chooses Inter-MSF MWE in the $2^{nd}$ stage of Bor$\dot{u}$vka is quite complicating. The $1^{st}$ stage of Bor$\dot{u}$vka has an advantage of obtaining Minimum Spanning Forest (MSF) with the least number of the edges, and on the other hand, Kruskal MST algorithm has an advantage of always obtaining MST though it deals with all the edges. Therefore, this paper suggests an Hybrid MST algorithm which consists of the merits of both Bor$\dot{u}$vka's $1^{st}$ stage and Kruskal MST algorithm. When applied additionally to 6 graphs, Hybrid MST algorithm has a same effect as that of Kruskal MST algorithm. Also, comparing the algorithm performance speed and capacity, Hybrid MST algorithm has shown the greatest performance Therefore, the suggested algorithm can be used as the generalized MST algorithm.

The Effects of Chitosan Pretreatment on the Dyeabilities and Antibacterial Activities of Persimmon Juice-Dyed Cotton Fabrics (키토산 전처리가 감즙염색 면직물의 염색성과 항균성에 미치는 효과)

  • Han, Young-Sook;Lee, Hye-Ja;Kim, Jung-Hee
    • Journal of the Korean Home Economics Association
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    • v.43 no.2
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    • pp.115-126
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    • 2005
  • Environmentally and human compatible chitosan were pretreated on cotton fabrics which were then dyed with 100% persimmon juice. The chitosan concentration was 1% and the chitosan types were high molecular weight chitosan (1980cps), low molecular weight chitosan (18첸), chitosan oligomer and water soluble chitosan. The properties of the fabric surfaces, the dyeabilities, the color fastnesses, the antibacterial activities, the strengths, the elongations and the drape stiffnesses were evaluated. The properties of the chitosanpretreated, persimmon juice-dyed cotton fabrics (CLP) were compared to those of the untreated (CN), chitosan treated (CL) and persimmon juice-dyed fabrics (CP). The results were as follows. The fibers extruded from the surface of CN decreased on CP. The air between the fibers within CN were substituted by chitosan solution or persimmon juiceand decreased within CLP according to SEM observations. The effects of chitosan treatment, the chitosan molecular weights and the degrees of deacetylation of chitosan on the dyeabilities of the persimmon juice-dyed cotton fabric were not distinct. The curing after chitosan padding improved the dyeabilities of CLP compare to noncuring. The strengths of CP decreased and those of CL increased, compared to those of CN. The strengths of CLP were greater than those of CP. The elogations of CP and CL were greater than those of CN. The strengths and elongations of CLP were greater than those of CN. The chitosan treatments improved the strengths but not the elongations. The drape stiffnesses of CL, CP and CLP were greater than those of CN. The antibacterial activites of chitosan pretreated, persimmon juice-dyed cotton fabrics against Staphylococcus aureus were increased by more than 98% by persimmon juice.

The Estrogenicity and Reproductive Toxicity by Combined Treatment of Bisphenol A and Benzyl butyl phthalate during Gestation, Lactation Period in Rats

  • Hwang, Seong-Hee;Kim, Jeong-Hyun;Kang, Hee-Joo;Kim, Hyun-Soo;Kim, Kyong-Tae;Kim, Pan-Gyi
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2004.06a
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    • pp.185-187
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    • 2004
  • The co-administration of BPA and BBP induced slow weight gain compared with single administration in dams. Also, such mixture induced low neonatal body weights in next generation. The dams treated with BPA and BBP showed significant organ weight changes in liver, spleen exposed during lactational periods. But the dams exposed during lactational periods showed significant organ weight changes not only in liver, spleen but also in kidney, uterus and ovary. The F1 female rats exposed during lactation periods showed significant organ weight changes in liver, spleen, ovary. The F1 male rats showed significant organ weight changes in liver, kidney, epididymis, vesicular glands, prostate. However no clear synergistic effects of BPA and BBP could be found. Estrogen receptor ${\alpha}$ expression by BPA and BBP in the uterus(dam, F1 female) and testis(F1 male) were studied. There was no significant different $ER{\alpha}$ expression pattern between control and treated groups. But $ER{\alpha}$ expression were increased in F1 male testis and female uterus. F1 male showed distinct $ER{\alpha}$ expression, especially in the group of lactational combined exposure. Synergistic $ER{\alpha}$ expression was found by combined treatment of BPA and BBP.

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Two Distinct Isozymes of Repair Protein Carboxyl O-Methyltransferase from Porcine Brain

  • Park, In-Ho;Son, Min-Sik;Son, Young-Jin;Moon, Hyung-In;Han, Jeung-Whan;Lee, Hyang-Woo;Hong, Sung-Youl
    • BMB Reports
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    • v.32 no.3
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    • pp.299-305
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    • 1999
  • Protein carboxyl O-methyltransferase (PCMT) catalyzes the transfer of a methyl group from Sadenosyl-L-methionine to free carboxyl groups of methyl-accepting substrate proteins. Two isozymes were separated by DEAE-Sephacel chromatography from porcine brain cytosol and designated PCMT I and II. Isozymes I and II were further purified by adenosyl homocysteine-Sepharose 4B and Superose HR 12 chromatography. The molecular weights of the purified PCMT I and II were determined by mass spectrometry to be 20,138 Da and 25,574 Da, respectively. The two enzymes displayed different isoelectric points; 7.9 for PCMT I and 5.3 for PCMT II. Isozymes I and II exhibited similar substrate specificities when tested with various methyl-accepting proteins. Myelin basic protein, a component of myelinated neurons, was found to be an excellent methyl-accepting substrate for both PCMT isozymes with different $K_m$ values, $21.1\;{\mu}M$ for PCMT I and $10.6\;{\mu}M$ for PCMT II. The PCMT activity and methyl-accepting capacity displayed similar distribution in the various brain regions with an exception of the lower values in the cerebellum. The overall distribution may relate to a general function of protein repair by PCMT in the brain.

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Design of Evaluation Method for Business Models Considering Spectrum Sharing using Analytic Hierarchy Process(AHP) Method (AHP를 이용한 주파수 공유 비즈니스 모델 평가방법 설계)

  • Kim, Taehan;Park, Hyun Min
    • The Journal of the Korea Contents Association
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    • v.15 no.12
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    • pp.525-533
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    • 2015
  • The evolution of spectrum sharing technology enables the creation of many business scenarios and business models such as TV white space service. Business models considering spectrum sharing should guarantee economic feasibility for service providers and increasing benefit for service users. In addition, new business models should contribute to economic activation in the wireless telecommunication service industry. It is therefore necessary to design quantitative evaluation methods for selection of the best business models. The methods should reflect the various points of view of valuation. Our research addresses evaluation method for business models considering spectrum sharing. We define evaluation indicators to reflect the distinct characteristics of spectrum sharing. Also, we adopt analytic hierarchy process(AHP) to derive the weights of each indicator to evaluate business models considering spectrum sharing.

The Wage Distribution Structure of Korean Manufacturing Industry (한국 제조업의 임금분포구조)

  • Chung, Kang-Soo;Kim, Bum-Sik;Lee, Cheol-Won
    • Journal of Labour Economics
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    • v.29 no.2
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    • pp.67-116
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    • 2006
  • This study directly analyzes the wage distributions rather than indirectly looking at a few of their moments. It also investigates wage distributions using various descriptive and semi-parametric methods. The wage distributions of Korean manufacturing industries can in general be represented by three distinct forms, underdeveloped, advanced and the medium of the two. The discrepancies in these distribution forms are explained by differences in the labor-type distributions and their weights in the composition of wage distribution forms, and further clarified through various descriptive statistics based on them. However, the descriptive statistical analysis has a limit in that it shows mixed outcomes of different categoric variables. Then, this problem is resolved by applying a semi-parametric estimation of hazard function and the marginal effect evaluations of variable changes on estimated distributions not on the function. As a result of this marginal analysis, the common features and differences of categoric variables and their intensities of effects on distributions are revealed.

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