• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권1호
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• pp.62-68
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• 2023

The treatment of complicated anterior cerebral artery aneurysms remains challenging. Here, the authors describe a case of ruptured complicated A3 aneurysm, which was treated with trapping and in-situ bypass. A 47-year-old man presented to the emergency department with severe headache and vomiting. Computed tomography illustrated acute intracerebral hemorrhage in the right frontal lobe. Digital subtraction angiography (DSA) confirmed a ruptured fusiform A3 aneurysm with lobulation and a daughter sac. Trapping of the ruptured fusiform A3 aneurysm and distal end-to-side A4 anastomosis was performed. DSA on postoperative day 7 showed mild vasospasm to the afferent artery. However, 2 months later, DSA demonstrated that the antegrade flow through the anastomosis site had recovered. Thus, surgeons should be aware of the possibility of postsurgical vasospasm of anastomosed arteries, especially in cases of ruptured aneurysms.

• Journal of Korean Neurosurgical Society
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• 제49권2호
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• pp.97-101
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• 2011

Objective : It is technically difficult to treat wide-necked intracranial aneurysms by the endovascular method. Various tools and techniques have been introduced to overcome the related technical limitations. The purpose of this study was to evaluate the radiologic and clinical results of widenecked intracranial aneurysm treatment using the endovascular method. Methods : Fifteen aneurysms in 15 patients were treated by the endovascular method from October 2009 to August 2010. Seven patients presented with subarachnoid hemorrhage (SAH), seven patients had unruptured aneurysms, and one patient had an intracerebral hemorrhage and intraventricular hemorrhage due to an incompletely clipped aneurysm. The mean dome-to-neck ratio was 1.1 (range, 0.6-1.7) and the mean height-to-neck ratio was 1.1 (range, 0.6-2.0). We used double microcatheters instead of a stent or a balloon for the first trial. When we failed to make a stable coil frame with two coils, we used a stent-assisted technique. Results : All aneurysms were successfully embolized. Eleven aneurysms (73%) were embolized by the double microcatheter technique without stent insertion, and four aneurysms (27%) were treated by stent-assisted coil embolization. One case had subclinical procedure-related intraoperative hemorrhage. Another case had procedure-related thromboembolism in the left distal anterior cerebral artery. During the follow-up period, one patient (7%) had a recanalized aneurysmal neck 12 months after coil embolization. The recurrent aneurysm was treated by stent-assisted coil embolization. Conclusion : We successfully treated 15 wide-necked intracranial aneurysms by the endovascular method. More clinical data with longer follow-up periods are needed to establish the use of endovascular treatment for wide-necked aneurysm.

• Korean Journal of Radiology
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• 제21권5호
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• pp.582-587
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• 2020

Objective: Endovascular thrombectomy (EVT) fails in approximately 20% of anterior circulation large vessel occlusion (AC-LVO). Nonetheless, the factors that affect clinical outcomes of non-recanalized AC-LVO despite EVT are less studied. The purpose of this study was to identify the factors affecting clinical outcomes in non-recanalized AC-LVO patients despite EVT. Materials and Methods: This was a retrospective analysis of clinical and imaging data from 136 consecutive patients who demonstrated recanalization failure (modified thrombolysis in cerebral ischemia [mTICI], 0-2a) despite EVT for AC-LVO. Data were collected in prospectively maintained registries at 16 stroke centers. Collateral status was categorized into good or poor based on the CT angiogram, and the mTICI was categorized as 0-1 or 2a on the final angiogram. Patients with good (modified Rankin Scale [mRS], 0-2) and poor outcomes (mRS, 3-6) were compared in multivariate analysis to evaluate the factors associated with a good outcome. Results: Thirty-five patients (25.7%) had good outcomes. The good outcome group was younger (odds ratio [OR], 0.962; 95% confidence interval [CI], 0.932-0.992; p = 0.015), had a lower incidence of hypertension (OR, 0.380; 95% CI, 0.173-0.839; p = 0.017) and distal internal carotid artery involvement (OR, 0.149; 95% CI, 0.043-0.520; p = 0.003), lower initial National Institute of Health Stroke Scale (NIHSS) (OR, 0.789; 95% CI, 0.713-0.873; p < 0.001) and good collateral status (OR, 13.818; 95% CI, 3.971-48.090; p < 0.001). In multivariate analysis, the initial NIHSS (OR, 0.760; 95% CI, 0.638-0.905; p = 0.002), good collateral status (OR, 14.130; 95% CI, 2.264-88.212; p = 0.005) and mTICI 2a recanalization (OR, 5.636; 95% CI, 1.216-26.119; p = 0.027) remained as independent factors with good outcome in non-recanalized patients. Conclusion: Baseline NIHSS score, good collateral status, and mTICI 2a recanalization remained independently associated with clinical outcome in non-recanalized patients. mTICI 2a recanalization would benefit patients with good collaterals in non-recanalized AC-LVO patients despite EVT.

• 한국산학기술학회논문지
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• 제18권8호
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• pp.240-247
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• 2017

자기공명혈관영상(magnetic resonance angiography: MRA)을 이용한 뇌혈관검사가 증가하면서 비파열 동맥류의 발견이 많아졌다. 비파열 동맥류(unruptured intracranial aneurysm: UIA)의 병태생리 이해를 위해 비파열 동맥류의 분포와 관련요인을 아는 것이 도움이 될 것으로 생각한다. 환자군은 건강검진 시 MRA를 시행받은 사람을 대상으로 하였다. 비파열 동맥류의 발생과 위험요인(나이, 성별, 고혈압, 당뇨, 흡연, 음주력, 관상동맥질환)을 크기(3 mm이상 대 3 mm미만)와 다발성 동맥류(단일 대 다발성 동맥류)에 따라 비교하였다. 그리고 위치에 따른 비파열 동맥류 발생 빈도를 비교하였다. 2007년 1월부터 2016년 12월까지 건강검진 센터를 방문하여 건강검진을 받은 사람을 대상으로 하였다. 건강검진을 받은 187166명의 사람 중 18954명이 MRA를 찍었으며, 이 중 367명(1.93%)이 비파열 동맥류를 보였다. 3 mm이상과 3 mm미만의 동맥류를 비교하였을 때 3 mm이상의 동맥류 환자군에서 평균 나이가 유의하게 높았다(3 mm이상 $57.16{\pm}8.47$ 대 3 mm미만 $55.12{\pm}8.19$; p=0.07). 고밀도 지질단백질(high-density lipoprotein)은 3 mm이상의 동맥류 환자군에서 유의하게 높았다(3 mm 이상 $55.95{\pm}16.03$ 대 3 mm미만 $50.85{\pm}13.65$; p=0.007). 고혈압은 다발성 동맥류 환자군에서 의미있게 높은 경향을 보였다(단일 동맥류 399명 중 153명(38.3%) 대 다발성 동맥류 35명 중 19명 (54.3%); p=0.065). 3mm미만의 동맥류는 내경동맥 말단부(34.3%)와 중대뇌동맥 분기부(16.4%)에서 호발하였다(p=0.003). 3 mm이상의 동맥류는 내경동맥 말단부(43.3%)와 중대뇌동맥 분기부(13.4%) 및 앞교통동맥(13.4%)에서 호발하였다(p=0.003). 동맥류는 크기 차이와 단일 혹은 다발성에 따라 서로 다른 위험요인과의 상관성을 보였으나, 두가지 위험요인 모두 혈관의 퇴행성 변화와 혈류역학적 장애가 동맥류 발생의 원인이 될 수 있다는 것을 보여준다.