• 수산해양교육연구
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• 제26권4호
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• pp.923-933
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• 2014

The purpose of this study was to investigate the moderating effect of cultural disposition in the relationship between parenting and academic achievement. Five-hundred thirty five middle school students(male 247; female, 288) participated in this study, These students completed parenting scale and Individualism-Collectivism Scale. Academic achievement was calculated using academic scores from language, english, mathematics and science. Collected data were analyzed using multiple regression. The major findings of this study can be summarized as follows. First, parenting was significantly associated with academic achievement albeit weak. Second, influence of affective and autonomy parenting on academic achievement for both father and mother were not significant. Third, moderating effects of individualism were significant in only fathers' autonomy parenting. Fourth, moderating effects of collectivism were significant in fathers' affective parenting and autonomy parenting. These results were discussed in relation to pervious studies. Finally limitations were commented and future study were suggested.

• 지식경영연구
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• 제19권1호
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• pp.41-57
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• 2018

While there are lots of studies on examining the effects of social rapport in many research areas, however, there is a little work in examining the effect of the social rapport in social network service (SNS) contexts. Thus, this study attempts to examine the effect of social rapport in SNS settings. To address the research questions, this study has presented its hypotheses and conducted three experimental approaches by collecting 180 data from student subjects who have prior experiences on using SNSs to verify the hypotheses. This study has examined three experiments the effects of characteristics of Facebook(i.e. the number of mutual friends, the number of post likes, and the post personalities) on the social rapport and user responses. This study has conducted two-way ANOVA to verity its proposed research hypotheses. Based on three experiments, this study found that both the effects of the number of post likes and the number of post likes on the social rapport were not significant. Based upon empirical findings, this study has demonstrated how the effects of social rapports in SNSs were different from those of previous studies, and brought more attentions to the relevant literature.

• 약학회지
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• 제51권3호
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• pp.169-173
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• 2007

The aim of this study was to investigate the effect of morin on the pharmacokinetics of nifedipine in rats. The pharmacokinetic parameters of nifedipine were measured after the oral administration of nifedipine (5 mg/kg) in the presence or absence of morin (1.5, 7.5 and 15 mg/kg, respectively). Compared to the control groups, the presence of 7.5 mg/kg and 15 mg/kg of morin significantly (p<0.05) increased the area under the plasma concentration-time curve (AUC) of nifedipine by 48.5${\sim}$68.2%, and the peak concentration (C$_{max}$,) of nifedipine by 59.9~84.2%. The absolute bioavailability(AB%) of nifedipine was significantly (p<0.05) increased by 21.5${\sim}$24.5% compared to the control (14.5%). While there was no significant change in the time to reach the peak plasma concentration (T$_{max}$) and the terminal half-life (T$_{1/2}$) of nifedipine in the presence of morin. It might be suggested that morin altered disposition of nifedipine by inhibition of both the first-pass metabolism and p-glycoprotein (P-gp) efflux pump in the small intestine of rats. In conclusion, the presence of morin significantly enhanced the oral bioavailability of nifedipine, suggesting that concurrent use of morin or morin-containing dietary supplement with nifedipine should require close monitoring for potential drug interaction.

• Asia pacific journal of information systems
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• 제15권3호
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• pp.187-207
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• 2005

In the Internet-based B2C e-commerce, trust has been recognized as a critical factor to reduce uncertainties, through interacting with a well-known specific shopping mall. In this study, we view customer trust as not a unitary concept but multidimensional one consisted of the trustworthiness of trustee, familiarity with the specific shopping-mall, disposition to trust, and institution-based trust. In this study, first, we considered the trustworthiness of trustee consisted of capability, benevolence, and integrity as one of the major factors to build customer trust on the specific Internet shopping-mall. In the context of the Internet e-commerce, the role of institutional structures is very important to assure the customer trust from the various opportunistic behaviors because of the characteristics of internet-based commerce such as impersonality, the lack of information on the other party, and the transactions with a number of anonymous people. Second, we examined the effect of the institution-based trust built by institutional structures on customer trust. Third, we examined the effect of customer trust and familiarity on retaining customer loyalty. Our findings showed that customer trust and familiarity played a major role in retaining customer loyalty with the specific shopping-mall. In conclusions, we discussed the strategies to build the customer loyalty for maintaining the customer. We suggest customer trust and familiarity for the factors to bind the customer with the specific shopping-mall based on these results.

• 한국가정과학회지
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• 제7권1호
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• pp.51-67
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• 2004

This study analyzed the effects of nutrition technicians' hygiene education on cooking workers' performance of hygiene management in order to ensure the security of school meals. The situation of cooking workers' disposition in subject schools was elementary school(51.1%) and middle school(48.9%) and the type of meals was rural area type(54.2%), urban type(36.5%). and island and isolated area type(9.3%). The methods of meals management were single cooking(88.2%) and joint cooking and management(11.8%). The type of distributing meals was distributing in a dining room(93.5%), in a classroom(3.7%), and in both dining room and classroom(2.8%). Nutrition technicians' employment form included regular(53.5%) and daily(88.2%). Their education was junior college graduate(50.2%), university graduate(44.8%). and graduate school students(5.0%). Cooking workers' employment form included daily(88.2%) and regular (11.1%). suggesting that most were regular. Most cooking workers(77.4%) had at least high school certificate. Regarding the situation of cooking workers' disposition in subject schools, the number of student per one cooking worker was found as 91-120(37.2%), 61-90(22.6%). 60 and under(21.l %). 121-15006.7%). and 151 and over(2.5%). Cooking workers' level of performance of hygiene management was post-working stage(66.37/75 marks), pre-working stage(64.22/75 marks). and working stage(20.34/25 marks), The counting of meals articles in a pre-working stage(20.34/25 marks). temperature and required time in a working stage(18.78/25 marks), and machinery equipment and hygiene in a pre-working stage(21.40/25 marks) showed lowest of performance, which suggest poor service of hygiene. Cooking workers' performance of hygiene management by working stage showed the significant difference with school class(p<.001), type of schools with meals(p<.05). state of cooking workers' employment(p<.001), and cooking worker's disposition(p<.05). A working stage showed the significant difference with type of schools with meals(p<.05). A post-working stage showed the significant difference according to type of schools with meals(p<.05), and the methods of meals management(p<.05), and cooking workers' disposition(p<.05). In the execution of hygiene education, individual hygiene was highest(94.8%), followed by the management of machinery equipment and tools(89.7%), food poisoning and microorganism(94.7%), and the method of food treatment(76.4%). A yearly plan of hygiene education included established(83.9%) and not established(l6.1%). Regular education included not executed(25.1%), 2-3 times a month(l6.1%), and more than 4 a month(4.0%) and occasional education was not executed(57.0%), 1-3 times a month(26.3%), and more than 4 a month(l5.7%). In the methods for hygiene education, oral education(95.7%) was used most, followed by demonstration(10.5%), poster/photo(10.5%), video/slide(3.7%), and computer(3.7%). Frequency of improvement and complement of hygiene education included once a month(56.3%), once a year(20.7%), by quarter(l1.5%), and every six months(1l.5%). Newspaper was used most in materials of hygiene education, followed by internet, TV, nutrition technician's reeducation, information exchange between members, educational office's training, and reference book, and educational office's material. and symposium. Cooking workers' assessment of the effect of hygiene education was conducted through observation(56.8%), check table(l5.2%), question(l4.0%), and examination(14.0%). The reason of cooking workers' low level of performance included habitual custom(53.9%), lack of understanding(20.4%), overwork(l4.6%), and lack of knowledge(l1.l%) and the reason of difficulty in hygiene education included lack of time(55.3%), lack of understanding(27.6%), lack of knowledge and information(8.7%), and lack of budget(48.0%).

• The Korean Journal of Physiology and Pharmacology
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• 제18권3호
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• pp.233-239
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• 2014

The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-${\alpha}$ levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to $17{\alpha}$-ethinylestradiol. Behavioral analysis by measuring immobility time in forced swimming test and open field test, serum and hippocampal corticosterone and TNF-${\alpha}$ along with hippocampal kynurenine/tryptophan ratio were determined in mature ovariectomized rats treated orally either by HP at three different doses 125, 250, and 500 mg/kg/day or by $17{\alpha}$-ethinylestradiol $30{\mu}g/kg/day$ for 30 days. Ovariectomized rats showed significant increase in immobility time in the forced swimming test. Along with elevation in serum and hippocampal TNF-${\alpha}$ and corticosterone levels associated with significant increase in hippocampal kynurenine/tryptophan ratio. Immobility time in the forced swimming test was decreased in rats treated by different doses of HP in a dose dependent manner and $17{\alpha}$-ethinylestradiol with no concomitant changes in the open field test. Only Rats treated with HP exhibited significant decrease in the elevated serum and hippocampal TNF-${\alpha}$ and corticosterone, which couldn't explain the associated insignificant effect on hippocampaus kynurenine/tryptophan ratio in comparison to ovariectomized untreated rats. It is concluded that increased tryptophan metabolism toward kynurenine secondary to elevated corticosterone and TNF-${\alpha}$ might be one of the pathohphysiological mechanisms that could explain depression like state observed in this rat model. Further, the observed attenuating effect of HP on TNF-${\alpha}$ and corticosterone could contribute in its antidepressant effect in this animal model by other ways than their effects on tryptophan-kynurenine metabolism pathway.

• 디지털융복합연구
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• 제14권1호
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• pp.91-97
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• 2016

최근 디지털 융합이 가속화 되면서 쇼핑에 있어서도 전통적인 매장과 온라인 및 모바일 매장에서의 채널 경계가 모호해지고 있다. 특히 동일한 쇼핑에도 여러 채널을 동시에 이용해 정보 검색 및 구매 행위에 적극 활용하는 옴니채널 쇼핑이 급속히 가속화되고 있다. 이에 따라 마케팅, 경영정보, 컴퓨터 공학 등 다양한 분야에서 옴니채널 쇼핑에 대한 활발한 연구가 진행 중이나 아직까지 소비자의 심리적 기질 차에 초점을 두고 이것이 옴니채널 쇼핑과 어떻게 연관되는 지를 본 연구는 거의 없다. 본 연구는 실험을 통해 소비자가 더 외향적(vs. 내성적) 일수록 동일 제품의 쇼핑에 있어서도 보다 옴니채널 쇼핑방식을 선호함을 검증하였다. 그리고 이러한 현상이 외향성이 높이는 다양성 추구 성향에 의해 매개됨을 보였다. 이 같은 연구결과를 토대로 본 연구는 실질적인 연구 결과의 적용을 제안하였으며, 아울러 소비자의 독특함 추구 성향 및 구조화 욕구와 옴니채널 쇼핑이 연계되어 연구될 수 있는 방안을 제시하였다.

• 약학회지
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• 제28권4호
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• pp.207-215
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• 1984

Effects of Ssang Wha Tang (SWT), a blended Chinease traditional medicine, on the pharmacokinetics of sulfobromophthalein (BSP) in the rats of hepatic failure induced by carbon tetrachloride were examined. The disposition of plasma BSP in carbon tetrachloride-treated rats (Group I) and in carbon tetrachloride+SWT-treated rats (Group II) followed a three-compartment model, while those in control group followed two-compartment model. GOT, GPT level and some pharmacokinetic paramiters like plasma clearance but except distribution volume (Vdss) recovered in Group II compared to Group I. Therefore, SWT seemed to have an apparent restoring effect of hepatic function damaged by carbon tetrachloride treatment. From the fact that Vdss of BSP in Group II was considered as an one of the probable mechanisms. More intensive increase in BSP-free fraction ($f_p$) in Group II than that in Group I might also explain the increases of BSP clearance and Vdss in Group II compared to Group I. Assuming no changes in hepatic plasma flow(Q) in each group, hepatic intrinsic clearance($CL^h_{int}$) decreased in Group I did not recovered not at all in Group II. Therefore SWT seemed not to have any restoring effect of true hepaticfunction to biotransform and excrete BSP, and the apparent restoring effect of SWT might be due only to the replacement of BSP-plasma protein binding. Whether $f_p$ is actually higer in Group II than in Group I, and Q is constant in each group are being examined in our laboratory. The changes of Q, which might lead to another conculusions, also should be taken into consideration to clarify the apparent hepatorestoring effect of SWT.

• 경영과정보연구
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• 제33권1호
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• pp.173-190
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• 2014

COSO(2013)보고서에 따르면 내부통제제도는 운영목적과 보고목적 및 준수목적, 세 가지 각 측면에서 기업의 목적을 달성에 대한 합리적인 확신을 제공하기 위해 설계된 절차이다. 내부회계관리제도는 이러한 세가지 통제목적 중 보고목적에 초점을 두고 있으며 자산보호 및 부정방지 프로그램을 포함한다. 따라서 취약한 내부회계관리제도를 가진 기업은 자산의 유용이나 횡령과 같은 부정이 발생할 가능성이 증가할 뿐만 아니라 부정이나 오류가 포함된 회계정보를 산출함으로써 경영자의 의사결정을 오도할 가능성이 증가하므로 기업가치에 악영향을 미칠 수 있다. 이와 관련하여 본 연구는 내부회계관리제도가 기업실패 가능성에 영향을 분석하였다. 내부회계관리제도의 특성은 내부회계관리제도의 중요한 취약점 존재여부와 운영인력 특성으로 측정하고 기업실패 가능성은 감사보고서에 기재된 계속기업불확실성으로 정의하였다. 분석결과, 기업실패 가능성은 내부회계관리제도의 취약점 존재여부와 양(+)의 관련성을 발견하였고 내부회계관리제도 운영인력의 경력및 공인회계사 자격여부와는 음(-)의 관련성을 발견하였다.

• Mass Spectrometry Letters
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• 제12권2호
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• pp.53-58
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• 2021

Previous in vitro studies have demonstrated that ginsenoside Rc inhibits UGT1A9, but there are no available data to indicate that ginsenoside Rc inhibits UGT1A9 in vivo. The effect of single and repeated intravenous injection of ginsenoside Rc was evaluated on the pharmacokinetics of mycophenolic acid. After injection of ginsenoside Rc (5 mg/kg for one day or 3 mg/kg for five days), 2-mg mycophenolic acid was intravenously injected, and the pharmacokinetics of mycophenolic acid and mycophenolic acid-β-glucuronide were determined. Concentrations of mycophenolic acid and its metabolite from rat plasma were analyzed using a liquid chromatography-triple quadrupole mass spectrometry. Single or repeated pretreatment with ginsenoside Rc had no significant effects on the pharmacokinetics of mycophenolic acid (P > 0.05): The mean difference in maximum plasma concentration (C_max) and area under the concentration-time curve (AUC_inf) were within 0.83- and 0.62-fold, respectively, compared with those in the absence of the ginsenoside Rc. These results indicate that ginsenoside Rc has a negligible effect on the disposition of mycophenolic acid in vivo despite in vitro findings indicating that ginsenoside Rc is a selective UGT1A9 inhibitor. As a result, ginsenoside Rc has little possibility of interacting with drugs that are metabolized by UGT1A9, including mycophenolic acid.