• 한국전통조경학회지
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• 제38권4호
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• pp.101-110
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• 2020

본 연구는 정원박람회에 출품한 작품 중에서 전통을 테마로 설정한 작가정원 14개소의 사례연구로서 문헌 분석과 현장 조사로 진행하였다. 전통재현을 결정하는 설계과정에 주목하고 작품마다 설계목표 수립, 전통재현의 대상 선정, 재현의 방법 결정, 경관구성요소 디자인 단계를 분석하여 다음과 같은 전통재현 특성과 시사점을 도출하였다. 첫째, 다수의 작가정원에서 전통구조물을 재현 대상으로 선정한 양상은 좁은 부지에 적합하고 주제 전달성이 좋다는 장점으로 이해할 수 있다. 이들은 작품명에 마당, 울, 부뚜막, 장독대, 취병과 석가산 등 전통구조물의 명칭을 넣어 설계의도를 직접 전달하였는데, Wall, 한국정원, 수원, 서울 장인처럼 간접적으로 표현한 작품들은 주제 전달성이 상대적으로 약하다. 선비, 여백, 풍류와 같이 재현 대상을 상징적으로 표현한 작품도 있었다. 둘째, 한옥마당을 재현하면서 잔디와 석재로 포장한 정원, 수원화성 성곽과 망루 서북공심돈(西北空心墩)을 분리하고 연계성 없는 용연(龍淵)을 미니어처 형태로 배치한 정원과 낙안읍성을 모티브로 하여 휴게공간에 낮은 장식담장으로 재현한 정원은 전통에 대한 깊이 있는 이해가 필요함을 보여준다. 반면 전통정원의 입지 선택, 주변 환경과 유기적 배치가 중요함을 보여준 한국정원, 한옥 중정이 가진 여백의 미와 선비가 누렸던 느림의 미학, 달밤 뱃놀이라는 풍류 문화를 재현한 작품들은 전통구조물 모사를 넘어 전통에 대한 이해가 정원문화와 정서로 확산된 양상이다. 셋째, 디자인과 관련하여 실제 크기의 전통구조물을 직설적 방법으로 재구성한 작품이 많았다. 취병으로 정원을 구획하고, 담장안에 부뚜막, 굴뚝, 텃밭 등으로 생활공간을 꾸미고, 경복궁, 소쇄원, 서석지를 대표하는 시설들을 유기적으로 배치하였다. 하지만 규모가 큰 수원화성과 낙안읍성을 추상적 방법으로 재현한 작품들로부터 핵심이 되는 디자인 요소의 취사선택, 구조물의 입면 구성, 공간의 스케일감에 대한 중요성을 인식하였다. 해체적 방법을 선택한 정원 중에는 원형 이미지와 멀어진 한옥 마당과 바자울의 사례가 있는 반면에 정육면체를 구성한 프레임만으로 표현한 여백의 정원과 많은 전통구조물로 달빛 스며든 선비의 사랑방을 재구성한 정원은 긍정적 사례이다. 현대적으로 디자인한 경관구성요소들을 전시한 서울 장인 정원, 직지심체정원, 풍류정원은 작가의 의도를 이해할 수 있는 설명이 필요하다.

• 한국안광학회지
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• 제20권3호
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• pp.319-324
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• 2015

목적: 3D TV의 근거리 시청에 따른 사위와 조절성폭주비의 변화와 회복 시점을 평가하고자 하였다. 방법: 3D TV 시청이 가능한 20~40대의 50명(남 30명, 여 20명)을 대상으로 하웰(Howell) 사위 카드를 사용하여 원거리(3 m)와 근거리(40 cm)에서 사위도를 측정하였다. 시청 거리는 1 m이며 시청 전, 시청 시간 30분 동안 10분 간격으로, 시청 이후 30분 동안 5분 간격으로 사위도를 측정하였다. 결과: 3D 영상 시청의 원거리 사위도 변화는 3D영상 시청 전 $-0.80{\pm}1.12{\Delta}$과 비교하여 10분, 30분 후 각각 $-0.98{\pm}1.37{\Delta}$(p=0.063), $-1.00{\pm}1.28{\Delta}$(p=0.024)로 외사위 경향으로 증가하였으며, 영상 시청 종료 후에는 외사위도가 감소하기 시작하여 20분 이후에는 $-0.78{\pm}1.11{\Delta}$로 시청 전 사위도 수준으로 회복되었다(p=0.322). 근거리 사위도 역시 영상 시청 전 $-4.36{\pm}3.66{\Delta}$과 비교하여 10분, 30분 후 각각 $-5.71{\pm}4.45{\Delta}$(p=0.000)과 $-6.58{\pm}4.63{\Delta}$(p=0.000)으로 외사위 방향으로 증가하였으며, 영상 시청 종료 후에는 외사위도가 감소하기 시작하여 25분 이후에는 $-4.34{\pm}3.67{\Delta}$로 시청 전 사위도 수준으로 회복되었다(p=0.322). 조절성폭주비는 영상 시청 전 $4.92{\pm}1.17{\Delta}/D$과 비교하여 영상시청 30분 후 $4.11{\pm}1.50{\Delta}/D$로 낮아졌으며(p=0.000), 영상 시청 종료 후에는 증가하기 시작하여 25분 후 $4.93{\pm}1.18{\Delta}/D$으로 시청 전으로 회복되었다(p=0.598). 결론: 근거리 3D TV 시청 시에 원거리보다 근거리의 외사위도가 더 크게 증가하였으며, 이로 인해 조절성폭주비는 낮아져 폭주부족의 경향을 보였다. 그러나 시청 후 25분 후에는 증가된 원거리와 근거리의 외사위도 모두 시청 전의 상태로 회복되었다. 따라서 3D TV 시청에 관한 합리적인 시청 권고안을 제시할 필요가 있는 것으로 본다.

• Journal of Chest Surgery
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• 제37권2호
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• pp.119-130
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• 2004

개심술 후 나타나는 심기능 저하는 수술 중 허혈로 인하여 생긴 심근손상에 의한 것으로 심근 허혈 상태가 반복되는 경우에 허혈 상태에 의한 심근기능의 손상이 축적되지 않고 오히려 먼저 온허혈 상태에 의하여 심근세포가 일종의 조건화 상태가 되어 허혈에 견디는 힘이 증가하여 장시간의 허혈이 오는 경우에 허혈에 의한 심근손상을 줄일 수 있다고 하여 이를 허혈성 전조건화라고 하는데, 허혈성 전조건화의 효과는 심근손상을 감소시키고, 재관류 시 심근회복에 좋은 영향을 미치며, 부정맥의 빈도를 감소시킨다고 하였다. 이러한 허혈성 전조건화를 본원에서 사용하는 중외1호 심정지액을 흰쥐의 적출 심장에 이용하여 심근보호 효과를 알아보고자 본 연구를 실시하였다. 대상 및 방법: 실험동물은 Sprague-Dawley계 수컷 흰쥐를 사용하였으며, 케뉼라를 삽관한 후 modified isolated working heart model에 부착 고정하였다. 관류과정은 비작업성 순환과 작업성 관류로 나누어 실시하였으며, 작업성 관류를 20분간 실시하고 이 때 심박동수, 대동맥압, 대동맥관류량, 관관류량을 측정기록 하였다. 대조군은 적출심장을 작업성 순환 20분 후 대동맥 차단과 동시에 심정지액을 주입하여 60분간 보존 후 재관류를 실시하여 회복시킨 군이며, 비교군은 허혈성 전조건화로 관류액 자체를 저산소증으로 만들어 허혈을 유발시킨 후 심정지액을 주입하여 60분간 보존시킨 군(제I군), 작업성 관류 20분 후 대동맥 차단을 실시하여 허혈을 유발시킨 후 재관류 없이 심근보호액을 45초(제II-1), 1분(제II-2군), 3분(제II-3군) 주입한 군과, 작업성 관류 20분 후 45초(제III-1군), 1분(제III-2군) 및 3분(제III-3군)간 대동맥 차단을 실시한 후 2분간 재관류를 실시하여 심장을 회복시킨 후 다시 동일 방법으로 2회 실시 후 심근보호액을 주입한 군으로 나누었으며, 모든 군에서 60분간 보존시킨 후 재관류를 실시하여 회복정도를 혈역학적 성적만을 측정 비교하였다. 결과: 자연 심박동 출현시간은 대조군에 비해 제I군, 제II-3군, 제III-2군 및 제III-3군에서 매우 늦은 출현시간을 보였고(p<0.01), 제II-1군과 제III-1군에서도 늦은 출현은 보였지만 통계적 유의성은 없었다(p=NS). 심박동수의 비교에서는 대조군에 비해 제III-1군이 가장 좋은 회복을 보였고(p<0.05), 비교군 간의 비교에서도 제III-1군이 제II-1군보다 좋은 회복을 보였다(p<0.05). 대동맥 수축기압에서도 제III-1군(p<0.05)에서 좋은 회복을 보였고, 대동맥 차단 군간에서도 제III-1군이 제II-1군에 비해 가장 좋은 회복을 보였다(1<0.01). 심박출량에서는 대조군에 비해 제III-1군이 좋은 회복률을 보였고(p<0.05), 비교군 간에서는 제III-1군이 제II-1군보다 좋은 회복을 보였으나 통계적 유의성은 없었지만(p=NS), 제III-2군이 제II-2군에 비해 좋은 회복을 보였다(p<0.05). 심부종의 평가에서는 대조군에 비해 제I군(p<0.01)과 제II-3군(p<0.05)에서 심부종이 심한 것을 알 수 있었다. 결론: 적출 심장만으로는 다른 장기의 영향을 배제한 경우에 심근보호액 자체보다 허혈 전조건화를 부여한 심근보호액 군에서 허혈 전조건화 시 심박동의 이상 징후가 출현하기 직전까지 짧은 시간 동안 허혈을 실시한 후 재관류시킨 뒤 심정지액을 주입하여 심장을 보호하는 것이 심기능 회복에 효과가 있는 것으로 생각되며, 앞으로도 계속적인 연구가 필요할 것이다.

• 한국유통학회지:유통연구
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• 제16권2호
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• pp.1-24
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• 2011

오프라인 구매환경과는 달리 온라인 환경에서는 제품을 직접 눈으로 확인하고 만져 볼 수 없다. 때문에 온라인 쇼핑몰을 구축하고 운영하는 입장에서는 보다 구체적인 제품정보를 제공해야 하며(김광석 2008), Alba (1997)는 제공된 정보의 질은 소비자들이 구매 후 만족을 얼마나 예상할 수 있는 가로 결정된다고 정의한 바 있다. 이에 패션 의류 온라인 쇼핑몰을 중심으로 실제 모델이 제품을 착용한 사진정보(실착사진)를 제공함으로써 실제 제품사용에 따른 결과를 제시하여 제품정보의 유용성을 높이고 있다. 한편 온라인 환경에서 소비자들의 제품에 대한 제한된 지각을 극복하는 또 다른 수단으로써, 가상제품경험은 가장 효과적인 것으로 논의되어 왔다(Jiang & Benbasat 2005). 그러나 가상현실도구의 도입과 지속적 활용에는 일반적인 텍스트/사진 정보와 비교해 높은 비용과 기술적 전문성을 요구한다(Shaffer 2006). 이는 특히 영세 소매상 입장에서 시장에 대한 진입장벽으로 작용하는 한편, 소비자의 정보처리과정에서는 오히려 단순한 형태의 정보에 비하여 더 높은 수준의 인지적 노력을 요구할 수 있다. 따라서 이러한 도구들의 활용하는 것이 소비자들의 정보과부하를 초래해 제품에 대한 핵심정보 취득을 방해하고, 소비자의 지각된 정보유용성에 부정적 영향을 미칠 수 있다. 이에 본 연구에서는 제품유형을 소비자들의 제품 사용상황에 따라 휴대제품과 설치제품으로 구분하고, 이때 정지사진, 실착사진, VR로 대별되는 제품정보의 형태에 따른 소비자들의 지각된 정보의 유용성, 쇼핑몰에 대한 태도와 품질평가, 구매의도, 재방문 의도를 측정하기 위한 실험을 진행했다. 그 결과 소비자 구매의도에 영향을 미치는 종속변수군에 대해 제품유형과 제품정보형태가 상호작용효과를 일으키는 것을 확인할 수 있었다.

• 유통과학연구
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• 제10권4호
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• pp.13-20
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• 2012

유동근무제는 고정된 시간대에만 근무하지 않고 조직과 종업원의 협의에 의하여 근무시간대를 유연하게 조절하는 제도를 의미한다. 대부분의 선행연구에서는 유동근무제가 성과나 생산성, 조직에 대한 태도, 결근율 및 이직률에 미치는 영향을 밝히는데 그 초점을 맞추었으나, 한국의 대부분 기업들이 아직 이 제도를 채택하지 않기 때문에 본 연구는 서울에 주소지를 둔 유통업체에 종사하는 노동자들을 대상으로 현장조사를 실시하여 노동자들의 개인적 특성이 유동근무제의 선호성향에 미치는 영향을 분석함으로써 제도도입을 위한 이론적 틀을 제공하는데 그 목적을 두고 있다. 본 연구의 결과를 요약하면 다음과 같다. 노동자들의 연령은 유동근무제의 선호성향에 영향을 미치지 않는 것으로 나타났다. 다만 통계적으로 유의하지는 않았지만 36세 이상의 노동자들은 35세 미만의 노동자들에 비해 선호성향이 낮은 것으로 나타났다. 남성의 선호성향이 여성보다 더 높게 나타났는데, 이것 역시 유동근무제는 자기개발과 직장생활을 공존하게 할 수 있어 아무래도 자기개발에 관심이 적은 여성보다는 남성들의 태도가 더 호의적인 것으로 분석되고 있다. 통제의 위치와 유동근무제에 대한 선호성향은 약한 상관관계가 존재하는 것으로 나타났는데 이것은 내적 통제를 지향하는 노동자일수록 유동근무제에 대해 호의적인 태도를 갖고 있음을 의미한다. 성취욕구가 높은 노동자일수록 유동근무제에 대해 호의적인 태도를 보여줬다. 성취욕구가 높은 사람들은 새로운 제도를 도입하는데 있어서 과감하게 도전을 하기 때문으로 보인다. 직무만족과 유동근무제의 선호성향과는 유의한 관련성을 나타내고 있지 않았다. 끝으로 본 연구의 한계를 제시하고 향후 연구의 방향을 제시한다.

• 미술자료
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• 제98권
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• pp.226-241
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• 2020

러시아 상트페테르부르크의 에르미타주 박물관 3층 맨 우측에는, 세계 유수의 실크로드 미술 컬렉션을 상설전시하는 "중앙아시아실"이 자리 잡고 있다. 20세기 초 실크로드를 학술조사한 러시아의 코즐로프(Pyotr Kozlov), 베레조프스키(Mikhail Berezovsky), 올덴부르그(Sergey Oldenburg) 등에 의해 수집된 고고 미술품 들이다. 에르미타주 박물관 소장의 방대한 이들 유물은 그 대강을 파악할 수 있도록 지역별로 분류하여 공개중이며, 이제까지 독일과 프랑스, 영국, 네덜란드, 한국, 일본 등에서 개최된 특별전시를 통해 그 일부를 소개하기도 하였다. 그리고 러시아 실크로드 탐험대의 성과물을 종합적으로 공개한 대형 기획전시 이 2008년에 에르미타주 박물관에서 개최됨으로써, 러시아의 실크로드 관련 유물이 세상에 본격적으로 알려지게 되었다. 이번에 간행된 『아장구자예술품(俄藏龜玆藝術品)』(2018)은 중국의 상해고적출판사(上海古籍出版社)가 에르미타주 박물관과 공동으로, 당관 소장 실크로드 유물 가운데 쿠차 지역의 예술품만을 선정하여 출판한 도록이다. 이 도록의 편집과 논고 및 유물 해설은 에르미타주 박물관 동양부(Oriental Department)의 시니어 큐레이터 키라 사모슉(Dr. Kira Samosyuk)이 담당하였다. 키라 박사는 하라호토(Khara-Khoto)와 서역(西域) 미술 전문가로, 그 이름이 국제적으로 널리 알려져 있는 중앙아시아 불교미술 연구의 석학이다. 본서에는 에르미타주 박물관 소장의 쿠차 지역 출토 유물을 망라하여, 중앙아시아 불교미술에 있어서의 쿠차 지역의 특징을 입체적으로 파악할 수 있도록 하였을 뿐만 아니라, 러시아 탐험대가 남긴 현장사진과 스케치 등에 이르기까지 빠짐없이 소개함으로써, 수집 유물 이외의 귀중한 정보도 아울러 제공하고 있다. 키라 사모슉 박사는 본서의 게재 논문 「The Art of the Kuche Buddhist Temples」에서, 러시아의 실크로드 탐험의 개요를 소개하고, 주로 불교시대 쿠차의 역사 전개 과정과 쿠차에 전래된 불교의 양상 그리고 석굴의 벽화 묘사와 그 연대 문제를 논한 후, 벽화의 주제와 소상(塑像), 석굴사원이 예배의 장으로서 어떻게 운용되고 있었는지에 대해 상세하게 언급하고 있다. 키라 박사는 결론으로서, 쿠차 문화는 불교 전파의 역사 가운데 독립적인 위치를 점하고 있었을 뿐만 아니라, 중국이나 유목세계의 여러 민족과 관계를 맺고 있었으며, 간다라 미술, 헬레니즘, 고대 이란, 중국 문화와의 관련성 속에서 독자적인 성격을 구축하였음을 논하고 있다. 그리고 쿠차 지역에서 형성된 문화는 타림분지뿐만 아니라 돈황(敦煌)과 중원(中原) 지역의 석굴예술에도 지대한 영향을 미치고 있다는 점으로 문장을 마감하고 있다. 키라 박사의 논고 가운데 주목할 부분은 쿠차 지역 석굴의 조성(造成) 연대(年代)에 관한 것이다. 그녀는 이제까지 여러 학자들에 의해 제기된 벽화의 조성 연대에 관한 견해를 소개하며, 벽화의 인물이 착용하고 있는 갑주(甲冑)의 도상(圖像) 특징 등을 소그드 미술 등 주변 지역에서 출토된 관련 자료와 비교하여, 키질의 조성 연대를 기존의 학설보다 백여 년 이상 소급해야 함을 주장하며, 5세기 이전으로 추정하고 있다. 그러나 쿠차 지역 석굴의 조성 시기의 문제는 석굴의 형식 문제를 비롯하여 불화(佛畫)의 주제(主題)와 양식(樣式), 안료(顔料)의 문제, 복식(服飾)이나 두발(頭髮), 제 장식(裝飾) 요소 등을 학제적(學際的) 연구 방법으로 재조명하고, 그 과정에 나타나는 주변 문화권과의 관련성 등을 종합적으로 고찰한 위에 방사성탄소 연대 측정 등 과학적 방법을 보조 자료로 활용하는 수밖에 없다. 에르미타주 박물관에는 제2차세계대전 때 베를린에서 전리품으로 가져온 벽화편이 다수 소장되어 있다. 일반인에게는 물론 학계에서도 그 행방을 전혀 모르고 있었던 이들 벽화편이 최근에 보존처리를 마치고 일반에게 상설전시를 통해 소개되고 있다. 본서 출판의 경위를 서술한 서언(序言)에는 이번 간행이 에르미타주 박물관 소장 쿠차 예술품의 제1차 출판이라고 한 점으로 보아, 아마도 보존처리가 끝난 독일 컬렉션을 소개하는 도록의 편집도 예정되어 있는 듯하다. 아울러 투르판과 호탄 지역 문물을 소개하는 도록의 간행도 기대해본다. 현재 쿠차의 석굴사원에서 절취한 벽화편은 러시아와 독일, 한국 등 여러 국가에 분장되어 있다. 이번 도록 출판을 계기로 쿠차 현지의 키질 석굴을 비롯한 제 석굴사원의 잔존벽화를 중심으로, 세계 각지에 흩어져 있는 벽화를 함께 소개하여 이들 석굴사원 벽화의 원래 모습을 온전하게 소개하는 종합도록의 간행도 필요할 것으로 본다. 그리고 동서의 문화가 혼합되어 있고 쿠차 지역 특유의 지역적 특성이 반영된 석굴사원의 벽화류 등을 소개하는 도록에는, 각 유물에 대한 보다 상세한 해설이 요망된다. 그리고 미술사 이외에도 보존과학적 측면에서의 안료 분석 등 학제적 조사연구 성과도 포함될 수 있기를 기대해본다. 작금의 중국 서부 개발 정책에 따라, 신장 지역의 오아시스에 인구가 과밀 거주함으로써 유발되는 기후변화 등으로 석굴사원의 벽화는 현재 심각한 위기에 처해있다. 이러한 난관을 타개하기 위해서는, 중국의 문화계뿐만 아니라 문화재 보존수복(保存修復)의 첨단 기술을 보유하고 있는 여러 국가들이 실크로드 석굴벽화의 보존수복을 위해 공동 노력하고 아울러 관련 인적자원 양성 등을 위해 보존과학센터를 운영하는 등 모두의 중지를 모아야할 때다. 본서는 20세기 초 서구 열강에 의해 추진된 실크로드의 고대 유적 조사 결과 가운데, 러시아 조사대가 쿠차 지역의 석굴사원을 중심으로 거둔 성과를 종합적으로 소개하는 출판물이지만, 향후 에르미타주 박물관 소장의 독일 컬렉션 벽화까지 전부 소개될 경우, 쿠차의 불교미술과 실크로드 연구에 크게 공헌할 것임에 틀림없다. 이런 의미에서 본서는 이제까지 축적되어 온 쿠차 지역에 대한 고고미술 연구의 마지막 퍼즐 조각이자 실크로드 연구의 새로운 방향을 제시한 학적 의미를 지니고 있다. 본서는 에르미타주 박물관의 실크로드 미술 연구의 성과물이자 새로운 편집 체계로서 학적 편의를 제공하였다는 점에서 큰 의미를 부여할 수 있으며, 이 모든 것을 기획하고 실크로드 미술 연구에 새로운 경지를 개척한 키라 사모슉 박사에게 경의를 표하는 바이다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.