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Inflammation and Insufficient or Disordered Sleep (염증 반응과 수면 장애)

  • Lee, Suk Jun;Kim, Jinkwan
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.3
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    • pp.97-104
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    • 2015
  • Sleep is not only an essential physiological function, but also serves important roles in promoting growth, maturation, and overall health of humans. There is increasing interest regarding the impact of sleep and its disorders on the regulation of inflammatory processes and end-organ morbidities, particularly in the context of metabolic and cardiovascular diseases (CVD) and their complications. Obstructive sleep apnea syndrome (OSAS) is an increasingly common health problem in children. In the last decade, the emergence of increasing obesity rates has further led to remarkable increases in the prevalence of OSAS, along with more prominent neurocognitive, behavioral, cardiovascular and metabolic morbidities. Although the underlying mechanisms leading to OSAS-induced morbidities are likely multifactorial and remain to be fully elucidated, activation of inflammatory pathways by OSAS has emerged as an important pathophysiological component of the end-organ injury associated with this disorder. To this effect, it would appear that OSAS could be viewed as a chronic, low-grade inflammatory disorder. Furthermore, the concurrent presence of obesity and OSAS poses a theoretically increased risk of OSAS-related complications. In this study, we will critically review the current state of research regarding the impact of insufficient and disrupted sleep and OSAS on the immune processes and inflammatory pathways that underlie childhood OSAS as a distinctive systemic inflammatory condition in children, and will explore potential interactions between OSAS and obesity.

The introduction of Traffic Inducement Security System in Korea - Centering on Curriculums - (한국의 교통유도경비 도입방안 -교과과정을 중심으로-)

  • Lee, Sang-Won;Lee,, Seung-Chal
    • Korean Security Journal
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    • no.25
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    • pp.147-164
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    • 2010
  • A variety of work zone including road single-sharing construction add surrounding disorder and increase inconvenience of vehicles and pedestrians and furthermore danger of traffic accidents, which sometimes result in human life damages. Traffic delay due to vehicles and users generating in the course of using large-scale multiplex facilities bring about a great economic loss. Now, a lot of regulations and laws related to traffic safety system on construction sites etc. are established, but can not display efficacy desirably. It brings about continuous economic loss due to human life accidents and delay. For the purpose of solving the problems, it is necessary to import systems such as traffic inducement Security (Japan) and traffic controller (CANADA, USA) This article suggest how improve civil safety and reduce Social cost. therefore This thesis aims at analyzing advanced cases of foreign countries, looking into Korean status, and presenting importing ways of traffic inducement Security appropriate to Korea. It is reasonable to grant grade1, grade2, and technical experts to traffic inducement Security who pass regulated educations and examinations. In addition, by reversing regulations and laws, it is necessary only those who have the licenses of traffic induction guarder etc. can establish construction sites and disordered places on roads. Theory educations for education time must include basic educations and expert educations. Basic educations must include understanding regulations and laws and understanding affairs. Expert educations must include traffic control, safety educations, understanding of traffic accidents, operation of traffic control facilities, and traffic accident settlements. Traffic affairs educations must include traffic induction affairs in sites (hand signals, safety material establishment, traffic accident settlements, and urgent treatments).

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Health Conditions, Activities of Daily Living, Depression, Sleep, and Cognitive Functions of the Elderly at Care Facilities and Their Related Factors (요양시설 노인들의 건강상태, 일상생활수행능력, 우울, 수면과 인지기능정도와 관련요인)

  • Kim, Jong-Im
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.11
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    • pp.463-473
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    • 2016
  • The purpose of this study was to investigate the relations between the cognitive functions, health conditions, activities of daily living, depression and sleep states among the elderly at care facilities. The subjects include 204 elderly people aged 65. The data collected were analyzed using descriptive statistics, the t-test, ANOVA, Pearson correlation, and hierarchical multiple regression. The findings show that the cognitive functions of the elderly at care facilities are related to their engagement in regular exercise, duration of residency, grade of care, lack of physical freedom, listening ability, state of teeth, urinary incontinence, activities of daily living, and state of sleep. Their cognitive functions had positive correlations with activities of daily living and negative correlations with state of sleep. Their cognitive impairment was significantly influenced by their engagement in regular exercise, duration of residency, grade of care, listening ability, ADL, IAD dependency, and sleep disorder. In short, the cognitive functions of the elderly at care facilities are highly related to their health conditions as perceived and felt by them. It is thus required to develop, apply, and consistently assess and manage cognitive rehabilitation training programs to provide interventions for the factors that influence their cognitive impairment.

Establishment of Early Diagnosis and Surgical Operative Method in Puppies with Congenital Patellar Luxation (선천성 슬개골탈구를 지닌 자견의 조기 진단법 및 외과적 수술법 확립)

  • 정순욱;박수현
    • Journal of Veterinary Clinics
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    • v.16 no.2
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    • pp.309-320
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    • 1999
  • Medial patellar luxation in dogs is one of the most common patellar problems presented to the veterinary practitioner. It is observed in toy and miniature breed and the majority of cases is a congenital form. Because of extensor mechanism's instability, it causes deformity and disorder in the growth of the affected limb when the luxation is left without treatment As lameness is not easily detectable in puppies, early diagnosis and correction are essential for therapy. Up to now, there has not been any reports refering to the diagnostic methods and the optimal age for correction in young dogs. Thirteen 45-90 days old puppies, have grade I and/or II medial patellar luxation. Only by palpation, all 13 dogs were diagnosed of patelar luxation. Skyline radiographic view was useful to interpret patellar morphology and depth of trochlear groove only above 60 days old. However, it was difficult to make definite diagnosis patellar luxation. The caudocranial and lateral radiographic view as well as ultrasonographic skyline view were not showed of patellar luxation. 2 puppies had unilateral patellar luxation and 11 puppies had bilateral patellar luxation which more serious on the left than on the right. Only 3 puppies among 11 puppies with bilateral patellar luxation were observed of lameness degree 1. Regardless of grade of patellar luxation and lameness, we performed trochlear chondroplasty using a U-shape sculpture blade to minimize cartilage injury, transposition of tibia tuberosity with No. 1 Supramid to align extensor mechanism and lateral imbrication. After surgery, we examined the operated animal daily for 10 days and on 15, 30 and 60 days after surgery respectively. After operation, pain and fever became normal on 7 days, swelling on 10 days, respectively. On 10 days after surgery, dogs showed normal standing position, and normal walking was observed in 15 days after surgery. In force plate analysis, the operated legs were normal weight bearing at 30 days after operation. After surgery, not only patellar luxation and clinical signs have been gradually reduced but also bone growth have become normal without showing growth physeal plate injury. The survival rate of puppies over 62 days old was 100%, while 42-45 days old 37.5%. The above results suggest that optimal age for surgical correction of congenital medial patellar luxation is recommended over 60 days old. In conclusion, combination of trochlear chondroplasty, transposition of tibia tuberosity, and lateral retinacular imbrication is appropriate for over 60 days old puppies to efficiently correct patellar luxation.

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Pattern of Computer Game Play and Emotional and Behavioral Characteristics in Upper Grade Elementary School Children (초등학교 고학년 아동의 컴퓨터 게임 양상과 정서 및 행동 특성)

  • Lee, Ja-Yeong;Park, Tae-Won;Lee, Moon-Sook;Cho, Eun-Cheong;Chung, Young-Chul;Hwang, Ik-Keun;Yang, Jong-Chul;Chung, Sang-Keun;Jung, Ae-Ja;Eun, Hong-Bae
    • Anxiety and mood
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    • v.4 no.2
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    • pp.135-141
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    • 2008
  • Objective : The purpose of this study was to investigate the relationship between the pattern of computer game play and emotional and behavioral characteristics of 5th and 6th grade elementary school children in Jeonju city. Methods : Fifth and sixth graders from two elementary schools (N=413, M=214, F=199) were chosen to participate in this study. The participants completed self-report questionnaires designed by the authors, and were also evaluated based on a computer game addiction scale, state-trait anxiety inventory for children, children's depression inventory and Piers-Harris children's self-esteem scale. The parents of the participants determined the disruptive behavior rating scale of the participants. Results : Positive links were reported between the pattern of computer game play (years of computer game experience, average length of each computer game play session, average time spent on computer game play per day, and average frequency of computer game play per week) and scores of computer game addiction scale. In addition, significant correlation was found between the internalized problems of children (trait anxiety, state anxiety, depression, and self-esteem), and computer game addiction scale score, among both sexes (p<0.01). There were significant correlations between game addiction scale score and inattention (p<0.01) as well as total attention deficit hyperactivity disorder (ADHD) score (p<0.05) in girls. Conclusion : Our findings suggest that computer game addiction is related to symptoms of internalizing, particularly to the trait anxiety. Significant positive correlations between game addiction scale score and externalized behavioral problems were found only in girls.

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The effects of Jajun-maum-dom-movement program on the attention and hyperactivity of middle school students (자전 동작이 중학생의 주의력 및 행동에 미치는 영향)

  • Kim, Se-Won;Jung, Young-Su;Chu, Key-One;Kim, Geun-Woo;Kim, Seung-Hyeon;Ko, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.4
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    • pp.79-97
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    • 2010
  • Objectives : The objective of this study is to investigate the effects of Jajun-maum-dom-movement program on the attention and hyperactivity of middle school students, Methods: Jajun-maum-dom-movement program was applied to 14 middle school students for 8 weeks, To measure the improvement of attention and decrease of hyperactivity, these tests were used - ADHD Diagnostic System(hereinafter ADS), Parent's Abbreviated Conners Rating Scale(hereinafter ACRS), Teacher's Korean ADHD Rating Scale(hereinafter K-ARS). For each variable in the 3 test methods, the results of before and after program were measured and then, the results were assessed by paired t-test, Interrelations between the resulted values of 10 variables were analyzed in these three groups: scores before program, scores after program, and change in scores before and after program, Among 10 variables, for variable showing significant difference by t-test, it was assessed by ANCOVA whether change in scores before and after program is affected by the grade and gender. Results: As for the changed score between before-the-program and after-the-program, in the ADS test, it was found that there is a significant effect in the "commission error" which is one of the indices showing the degree of hyperactivity, and "sensitivity(d')" which is one of the indices showing attention, and it was found that there is a significant effect in ACRS and K -ARSC total), Among the correlations of the 4 variables, "ACRS" and "K-ARSC total) ", which show the comprecessive criteria, have the positive correlation of significance in before-the-program, after-the-program and the changed score between before-the-program and after-the-program, However, there was no specific correlations among sub-variables about attention or hyperactivity, and in all of 4 variables, there was no significant degree of change according to grade or gender. Conclusions : As the results of assessment by ADHD Diagnostic System, Parent's Abbreviated Conners Rating Scale, Teacher's Korean ADHD Rating Scale to study the effects of Jajun-maum-dom-movement program on attention and hyperactivity, it is known that the program is helpful for improvement of attention and decrease of hyperactivity for the participated students.

Evaluation of Rotator Cuff Repair Using Korean Shoulder Scoring System

  • Shin, Sang-Jin;Lee, Juyeob;Ko, Young-Won;Park, Min-Gyue
    • Clinics in Shoulder and Elbow
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    • v.18 no.4
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    • pp.206-210
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    • 2015
  • Background: Assessment of the clinical outcomes after rotator cuff repair is essential for their effectiveness on treatment. The Korean Shoulder and Elbow Society devised the Korean Shoulder Scoring System (KSS) for patients with rotator cuff disorder. The purpose of this study was to evaluate the availability of the KSS for assessment of clinical outcomes in patients after arthroscopic rotator cuff repair, and for comparison with other appraisal scoring systems. Methods: A total of 130 patients with partial-thickness or full-thickness rotator cuff tear who underwent arthroscopic repair using a single row or double row suture bridge technique were enrolled. The average follow-up period was 25.9 months. All patients were classified according to various factors. Comparison within corresponding categories was performed, and the correlation between the KSS and other shoulder assessment methods including University of California Los Angeles (UCLA), Constant and American Shoulder and Elbow Surgeons (ASES) score was analyzed. Results: Total score of the KSS response had increased from 59.6 preoperatively to 88.96 at last follow-up. All KSS domains, including function, pain, satisfaction, range of motion, and muscle power had improved up to 24 months postoperatively. Statistical significance was observed mainly in preoperative measurements with number and size of torn tendons, and greater than or equal to grade 3 of fatty infiltration. The KSS was best correlated with the UCLA scoring system in both preoperative (r=0.785) and postoperative (r=0.951) measurements. Conclusions: The KSS was highly reliable and valid as a discriminative instrument, and it showed strong correlation with ASES and UCLA scoring systems.

The Development of a Social Skill Training Program for ADHD Children and It's Effect (ADHD 아동을 위한 사회기술훈련 프로그램의 개발과 효과)

  • Lee, Hye-Sug
    • The Korean Journal of Elementary Counseling
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    • v.6 no.1
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    • pp.171-191
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    • 2007
  • The purpose of this study is to develop social skill training in order to reduce problematic behaviors and improve peer relations for elementary school students who have ADHD(Attention Deficit Hyperactivity Disorder) and then verify its effectiveness. The problems for this study are as follows: Firstly, is the social skill training for students with ADHD effective in enhancing their self-esteem? Secondly, is the social skill training for students with ADHD effective in reducing their carelessness, hyperactivity and impulsive character? Thirdly, is the social skill training for students with ADHD effective in improving peer relations? Subjects were six 5th grade children who were selected by the ADHD-SC4 at P elementary school in Pyeongtaek. The social skill training consisted of 10 sessions which included forming friendship, recognizing, making friends, solving problems, reeducation and evaluation. Qualitative data were collected through self-esteem inventory, peer-relation test, self-reported scales for children and Conners' Teacher rating score for ADHD children. The collected data were analysed with t-test. Qualitative data were collected though teacher's interview and observation an the children. The results of the study were follows: First, the social skill training did not give a significant effect in enhancing the self-esteem of the children with ADHD. Second, the social skill training had a positive effect in reducing in attentiveness, hyperactivity and impulsive behavior of the children with ADHD. Third, the social skill training did not give a significant effect in improving the peer relations of the children with ADHD. Fourth the qualitative data showed that the social skill training had positive effect in enhancing over all classroom behavior.

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Idiopathic Hypertrophic Spinal Pachymeningitis with an Osteolytic Lesion

  • Jee, Tae Keun;Lee, Sun-Ho;Kim, Eun-Sang;Eoh, Whan
    • Journal of Korean Neurosurgical Society
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    • v.56 no.2
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    • pp.162-165
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    • 2014
  • Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a chronic, progressive, inflammatory disorder characterized by marked fibrosis of the spinal dura mater with unknown etiology. According to the location of the lesion, it might induce neurologic deficits by compression of spinal cord and nerve root. A 58-year old female with a 3-year history of progressive weakness in both lower extremities was referred to our institute. Spinal computed tomography (CT) scan showed an osteolytic lesion involving base of the C6 spinous process with adjacent epidural mass. Magnetic resonance imaging (MRI) revealed an epidural mass involving dorsal aspect of cervical spinal canal from C5 to C7 level, with low signal intensity on T1 and T2 weighted images and non-enhancement on T1 weighted-enhanced images. We decided to undertake surgical exploration. At the operation field, there was yellow colored, thickened fibrous tissue over the dura mater. The lesion was removed totally, and decompression of spinal cord was achieved. Symptoms improved partially after the operation. Histopathologically, fibrotic pachymeninges with scanty inflammatory cells was revealed, which was compatible with diagnosis of idiopathic hypertrophic pachymeningitis. Six months after operation, motor power grade of both lower extremities was normal on physical examination. However, the patient still complained of mild weakness in the right lower extremity. Although the nature of IHSP is generally indolent, decompressive surgery should be considered for the patient with definite or progressive neurologic symptoms in order to prevent further deterioration. In addition, IHSP can present as an osteolytic lesion. Differential diagnosis with neoplastic disease, including giant cell tumor, is important.

The Feasibility and Safety of Herbal Medication on Short Stature (성장치료를 위한 한약투여의 임상적 효과 및 안전성 평가)

  • Cheong, Jeong-Ook;Yang, Tae-Kyu;Koo, Bon-Hong;Lee, Sea-Yun
    • The Journal of Internal Korean Medicine
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    • v.22 no.4
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    • pp.513-517
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    • 2001
  • Objective : Recently many studies of herbal medication to promote growth have been implemented. The purpose of this study was to identify the feasibility and safety of herbal medication on short stature. Methods : 143 patients(87 males, 56 Females)who visited with short stature at Kangnam CHA Oriental Hospital From February 1999 to January 2000 and were treated during 6 months, were available for this study. We treated with 5 herbal medications.(Soeumin hyangbujapalmultang-gagambang, Soyangin yukmijihwangtang-gagambang, Taeumin chungsimyunjatang-gagambang, Boa-tang, Boikyangwi tang) At the begining of the treatment and after 6 months treatment, We measured height, weight and body mass index(BMI). And we investigated changes of aspartate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN), alkaline phosphatase(ALP), creatinine. Results: The distribution of ages was from 5 years old to 17 years old. After herbal treatment, mean height, mean weight, mean BMI and mean percentile grade increased $138.5{\pm}15.6$ to $141.9{\pm}15.1$, from $36.9{\pm}13.2$ to $38.9{\pm}13.2$, from $18.5{\pm}3.29$ to $18.7{\pm}3.21$, from $3.2{\pm}1.2$ to $3.4{\pm}1.2$. The contents of AST, ALT, BUN, ALP and Creatinine were not showed any significant change. Conclusions : In the results We recognized Short stature was showed prominent feasibility and safety of herbal medication. Herbal Medication in patients with short stature will improve height velocity without liver and kidney function disorders.

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