• Tunnel and Underground Space
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• v.31 no.6
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• pp.494-507
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• 2021

With the increasing use of TBM, research has recently been conducted in Korea to analyze TBM data with machine learning techniques to predict the ground in front of TBM, predict the exchange cycle of disk cutters, and predict the advance rate of TBM. In this study, classification prediction of rock characteristics of slurry shield TBM sites was made by combining traditional rock classification techniques and machine learning techniques widely used in various fields with machine data during TBM excavation. The items of rock characteristic classification criteria were set as RQD, uniaxial compression strength, and elastic wave speed, and the rock conditions for each item were classified into three classes: class 0 (good), 1 (normal), and 2 (poor), and machine learning was performed on six class algorithms. As a result, the ensemble model showed good performance, and the LigthtGBM model, which showed excellent results in learning speed as well as learning performance, was found to be optimal in the target site ground. Using the classification model for the three rock characteristics set in this study, it is believed that it will be possible to provide rock conditions for sections where ground information is not provided, which will help during excavation work.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.1
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• pp.109-128
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• 2022

The precise inspection for safety and diagnosis (PISD) of tunnel has been conducted by the special act on safety control of public structures. However, the present assessment for the segmental lining of TBM tunnel has limitation such as: NDTs for integrity, segmental configuration for field inspection, and consideration for jacking system. Even if the number of TBM tunnel is less than 1% of enrolled facility in FMS, more attention to maintenance should be necessary due to its usage such as multi-use facility and national important facility. Compared to NATM tunnel, excavated by drilling and blasting and then installed lining by cast-in-place within 6~12 m, TBM tunnel is cut out ground by disk and cutter-bit and then assembled 7 pieces of precast segment, 1.2~1.4 m wide. Different features of design, construction, and maintenance should be considered to be more exact evaluation of TBM tunnel. The characteristics of defect is categorized and analyzed with 11 operational TBM tunnels in domestic subway. To be more comprehend various particular defects, foreign studies have been also adapted. Crack and leakage are categorized in 7 patterns. Breakage/spalling and corrosion are also grouped into 3 patterns. Patterned defects or damages are fed back in design, construction, and are useful guidelines for maintenance stage in future.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.4
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• pp.265-272
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• 2022

The emergence and dissemination of carbapenemase-producing Enterobacteriaceae (CPE), particularly the Klebsiella pneumoniae carbapenemase-2 (KPC-2) producing Klebsiella pneumoniae, has been rapidly increasing worldwide and is becoming a serious public health threat. Since the epidemiology and characteristics of these KPC-2-producing K. pneumoniae vary according to the region and period under consideration, this study investigated the prevalence of carbapenemases and the epidemiological relationship of 78 carbapenem-resistant K. pneumoniae (CRKP) isolated from a tertiary hospital in Daejeon, from March 2017 to December 2020. The antimicrobial susceptibility tests were identified using the disk-diffusion method. PCR and DNA sequencing were used to determine the carbapenemase genes. In addition, molecular epidemiology was performed by multilocus sequence typing (MLST). Among the 78 CRKP isolates, 35 isolates (44.9%) were carbapenemase-producing K. pneumoniae (CPKP) and the major carbapenemase type was KPC-2 (30 isolates, 85.7%). The New Delhi metallo-enzyme-1 (NDM-1) and NDM-5 were identified in 4 isolates (11.4%) and 1 isolate (2.9%), respectively. Multilocus sequence typing (MLST) analysis showed 10 sequence types (STs) and the most prevalent ST was ST307 (51.4%, 18/35). All the ST307 isolates were KPC-2-producing K. pneumoniae and were multidrug-resistant (MDR). In addition, ST307 has gradually emerged during a four-year period. These findings indicate that continuous monitoring and proper infection control are needed to prevent the spread of KPC-2-producing K. pneumoniae ST307.

• Journal of the Korean Geotechnical Society
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• v.25 no.5
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• pp.75-86
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• 2009

Salt, one of the most common soluble materials in engineering soil, may have an effect on mechanical behaviors of soils under its cementation process. In order to investigate this natural phenomenon, non-soluble material by using glass beads is mixed with salt electrolyte and cemented by using oven to evaporate water. Three different sizes of glass bead particles, 0.26, 0.5, and 1.29 mm, with different salt concentration, 0, 0.1, 0.2, 0.5, 1.0, and 2.0M, are explored by using P- and S-waves, excited by bender elements and piezo disk elemets, respectively. The velocities of the P-wave and S-wave of the particulate medium cemented by salt show three stages with the degree of saturation: 1) S-wave velocities increase while P-wave velocities reduce with degree of saturation changing from 100% to 90%; 2) Both velocities are stable with degree of saturation varying from 90% to 10%; 3) The velocities change enormously when the specimens are nearly dry with degree of saturation from 10% to 0%. Besides, the resonance frequencies of S-wave show similar stages to the S-wave velocities. This study demonstrates meaningful trends of elastic wave characteristics of geo-materials according to the cementation of dissolved salt.

• Journal of the Korean Geotechnical Society
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• v.25 no.12
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• pp.5-12
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• 2009

As rock bolts become one of the main support systems in tunnels and underground structures, the integrity of the rock bolts affects the safety of these structures. The purpose of this study is the evaluation of rock bolt integrity using wavelet transforms of the guided ultrasonic waves by using transmission test in the field. After several rock bolts with various defect ratios are embedded into a large scale concrete block and rock mass, guided waves are generated by a piezo disk element and measured by an acoustic emission (AE) sensor. The captured signals are analyzed in the time-frequency domain using the wavelet transform based on a Gabor wavelet. Peak values in the time-frequency domain represent the interval of travel time of each echo. The energy velocities of the guided waves increase with an increase in the defect ratio. The suitable curing time for the evergy velocity analysis is proposed by the laboratory test, and in-situ tests are performed in two tunnelling sites to verify the applicability of rock bolt integrity tests performed after proposed curing time. This study proves that time-frequency domain analysis is an effective tool for the evaluation of the rock bolt integrity.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.2C
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• pp.85-93
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• 2010

The shear stiffness has become an important design parameter to understand the soil behavior. In particular, the elastic moduli and void ratio has been considered as important parameters for the design of the geotechnical structures. The objective of this paper is the development of the penetration type Field Velocity and Resistivity Probe (FVRP) which is able to assess the elastic moduli and void ratio based on the elastic wave velocities and electrical resistivity. The elastic waves including the compressional and shear wave are measured by piezo disk elements and bender elements. And the electrical resistivity is measured by the resistivity probe, which is manufactured and installed at the tip of the FVRP. The penetration tests are carried out in calibration chamber and field. In the laboratory calibration chamber test, after the sand-clay slurry mixtures are prepared and consolidated. The FVRP is progressively penetrated and the data are measured at each 1 cm. The field experiment is also carried out in the southern part of Korea Peninsular. Data gathering is performed in the depth of 6~20 m at each 10 cm. The elastic moduli and void ratio are estimated based on the analytical and empirical solutions by using the elastic wave velocities and electrical resistivity measured in the chamber and field. The void ratios based on the elastic wave velocities and the electrical resistivity are similar to the volume based void ratio. This study suggests that the FVRP, which evaluates the elastic wave velocities and the electrical resistivity, may be a useful instrument for assessing the elastic moduli and void ratio in soft soils.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5B
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• pp.497-502
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• 2009

The wastewater treatment by photocatalyst decomposes pollutants directly in water, and it is easy to decompose indecomposable organics and inorganic. and Especially, it has an advantage that there is no secondary production of pollutants. However, there will be many problems which are generated depending on the type of photocatalyst. The type of rotating photocatalyst minimizes previous problems, and advanced oxidation processes is possible by the application of rotating disc method. The consideration of the characteristics about various designs and operation factors is needed for the application of rotating photocatalyst system. In this study, rotating photocatalyst was manufactured for rotating disc method by fixing of $TiO_2$. The operation factors were derived for the wastewater treatment by the reaction of rotating photocatalyst. The contained quantity of $TiO_2$ was limited about 70%. The more the contained quantity of $TiO_2$ was increased, the more the treatment rate was continually increased. The optimum rotating photocatalyst was R4, and the contained quantity of $TiO_2$ was 36.8%. The more the exposed amount of UV is increased, the more the decomposition effect of TCODcr was continually increased. However, the adequate strength of light source must be determined by the consideration of economical efficiency. The more the speed of rotating photocatalyst is increased, the more treatment efficiency was increased. When UV lamp was not submerged in reactor, the wastewater treatment was efficient in the order of the depth of water 50%, 30%, 10%, 70%, 100%. This study is a basic research for the development of a system which treats organics in solar light.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.4
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• pp.125-133
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• 2023

Purpose : This study aimed to analyze the antibacterial activity of Liriope platyphylla ethanol extract (LPEE) against Streptococcus mutans and Porphyromonas gingivalis and to validate its potential for the prevention and treatment of dental caries, gingivitis, and periodontal disease. Methods : To verify the antibacterial effect of L. pulsatilla ethanolic extract (LPEE) against S. mutans and P. gingivalis, the disk diffusion method was used to determine the inhibition zones at concentrations of 50, 100, 200, and 300 mg/㎖. To determine the minimum inhibition concentration (MIC), the final dose of LPEE was .2, .4, .8, 1.6, 2.5, and 5.0 mg/㎖, and the minimum bactericidal concentration (MBC) was determined based on the MIC results. To confirm the growth inhibitory effect of LPEE on both pathogens, the absorbance was measured at 600 nm after each incubation for 0, 3, 6, 12, and 24 hr at concentrations of .8, 1.6, 2.5, and 5.0 mg/㎖. Results : The cytotoxicity of LPEE was evaluated and the cell viability was more than 70 % at 400 mg/㎖. Therefore, concentrations of 50, 100, 200, and 300 mg/㎖ were used in this study. The antimicrobial effect against S. mutans was seen at 100 mg/㎖ and grew in a concentration-dependent manner, while P. gingivalis was effective at 50 mg/㎖ with the dose dependency. The MIC was .8 mg/㎖ for both strains, and the MBC was 1.6 mg/㎖ with the same results. The growth inhibitory effect of LPEE on S. mutans and P. gingivalis was observed, even at low concentrations. Conclusion : The antibacterial effect of LPEE was evaluated through the analysis of MIC, MBC, and growth inhibition effect on S. mutans and P. gingivalis, which suggests LPEE might have the possibility of utilization as a preventive and therapeutic composition for oral diseases.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.633-640
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• 2023

With the recent development of static and dynamic modulated brachytherapy methods in brachytherapy, which use radiation shielding to modulate the dose distribution to deliver the dose, the amount of parameters and data required for dose calculation in inverse treatment planning and treatment plan optimization algorithms suitable for new directional beam intensity modulated brachytherapy is increasing. Although intensity-modulated brachytherapy enables accurate dose delivery of radiation, the increased amount of parameters and data increases the elapsed time required for dose calculation. In this study, a GPU-based CUDA-accelerated dose calculation algorithm was constructed to reduce the increase in dose calculation elapsed time. The acceleration of the calculation process was achieved by parallelizing the calculation of the system matrix of the volume of interest and the dose calculation. The developed algorithms were all performed in the same computing environment with an Intel (3.7 GHz, 6-core) CPU and a single NVIDIA GTX 1080ti graphics card, and the dose calculation time was evaluated by measuring only the dose calculation time, excluding the additional time required for loading data from disk and preprocessing operations. The results showed that the accelerated algorithm reduced the dose calculation time by about 30 times compared to the CPU-only calculation. The accelerated dose calculation algorithm can be expected to speed up treatment planning when new treatment plans need to be created to account for daily variations in applicator movement, such as in adaptive radiotherapy, or when dose calculation needs to account for changing parameters, such as in dynamically modulated brachytherapy.

• Journal of Life Science
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• v.34 no.6
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• pp.393-398
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• 2024

The purpose of this study was to verify the antifungal properties of various herbal medicines belonging to the Ranunculaceae family and to find an extraction method effective in inhibiting fungal growth. When antifungal activity was measured in a liquid medium with extracts obtained by either hot water extraction or organic solvent extraction of the herbal medicines Clematis apiifolia, Coptis chinensis, and Pusatilla chinensis, effective results were obtained from the chloroform extract. In addition, fungal growth inhibition experiments were performed on unicellular fungi, Candida albicans, Candida tropicalis, and Candida lusitaniae, and on filamentous fungi, such as Pythium ultimum, Aspergillus fumigatus, and Fusarium oxysporum, using disk diffusion experiments on solid media. It was confirmed that P. chinensis extract has excellent antifungal properties against Candida spp. and C. apiifolia extract against filamentous mold. Finally, GC-MS analysis was performed to explore the useful antifungal substances present in the extract. As a result of the study, thurbergenone from C. apiifolia and 16-hydroxycleroda-3, 13(14)-dien-15, 16-olide (16-HCDO) from C. chinensis were confirmed as antifungal candidates. In conclusion, it was confirmed that C. apiifolia, C. chinensis, and P. chinensis have antifungal activity against various fungi, and in GC-MS analysis, all herbal medicines were confirmed to have different antifungal candidates. These results indicate that the Ranunculaceae family has evolved in several directions for fungal resistance traits.